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23981
The Role of Inflammatory Cytokines and lncRNAs in the Pathogenesis of Atherosclerosis and Other Inflammatory Diseases: Focus on Sarcoidosis and Alzheimer’s Disease
Published 2025-01-01“…Description of the State of Knowledge Inflammatory cytokines, including interleukin-1β (IL-1β), tumor necrosis factor-α (TNF-α), and interleukin-6 (IL-6), orchestrate immune responses that exacerbate endothelial dysfunction, foam cell formation, and plaque instability. Concurrently, lncRNAs regulate gene expression through transcriptional and post-transcriptional mechanisms, influencing cellular processes such as macrophage polarization and smooth muscle cell proliferation. …”
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23982
Effect of Carboxymethyl chitosan-sodium alginate hydrogel loaded with Astragalus membranaceus-Panax notoginseng on wound healing in rats
Published 2025-01-01“…Skin wound healing is a complex physiological process that involves many different cell types and signaling molecules. In traditional Chinese medicine, A. membranaceus and Panax notoginseng are commonly used together for the treatment of wound injury for their significant efficacy. …”
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23983
Factors Associated with Road Accidents among Brazilian Motorcycle Couriers
Published 2012-01-01“…Young age (18 to 24 years compared to ≥25 years, odds ratio [OR]=1.77) speeding (OR=1.48), and use of cell phones while driving (OR=1.43) were factors independently associated with reports of accidents. …”
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23984
Ligand-Based Pharmacophore Modeling and Virtual Screening of RAD9 Inhibitors
Published 2013-01-01“…Human RAD9 is a key cell-cycle checkpoint protein that participates in DNA repair, activation of multiple cell cycle phase checkpoints, and apoptosis. …”
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23985
Acinetobacter baumannii Lipopolysaccharide Influences Adipokine Expression in 3T3-L1 Adipocytes
Published 2017-01-01“…We tested the effect of increasing concentrations of A. baumannii-derived LPS (10, 100, or 1000 ng/mL) on the 3T3-L1 adipocyte cell line. Exposure to LPS was found to increase the expression of several adipokines (e.g., MIP-2, MCP-1, TNF-α, IL-6, lipocalin-2, and FABP4) in 3T3-L1 adipocytes and significantly reduced the expression of leptin and adiponectin. …”
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23986
Development of a high-performance pseudocapacitive composite via electroless deposition of silver nanoparticles on micro-sized silicon
Published 2024-12-01“…Raman spectroscopy confirmed the formation of silver and silicon oxides. In a three-cell configuration, the low equivalent series resistance and charge transfer resistance indicated that Ag served as the conductive channel for charge transfer. …”
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23987
Automated Long-Term Monitoring of Parallel Microfluidic Operations Applying a Machine Vision-Assisted Positioning Method
Published 2014-01-01“…As microfluidics has been applied extensively in many cell and biochemical applications, monitoring the related processes is an important requirement. …”
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23988
Iron(ing) out parkinsonisms: The interplay of proteinopathy and ferroptosis in Parkinson's disease and tau-related parkinsonisms
Published 2025-02-01“…Thus, we explore the current findings relating to the relationship of parkinsonism proteinopathy (α-synuclein in PD, and tau in PSP/CBD) paralleled to a specific form of cell death, ferroptosis. Ferroptosis is characterised by iron-induced lipid peroxidation and several markers of this pathway have been identified to control intracellular iron fluctuations. …”
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23989
The Peroxisome Proliferator-Activated Receptor Gamma System Regulates Ultraviolet B-Induced Prostaglandin E2 Production in Human Epidermal Keratinocytes
Published 2010-01-01“…However, in several epithelial cell lines, ultraviolet B (UVB) has been shown to induce the nonenzymatic production of oxidized phospholipids that act as PPARγ agonists. …”
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23990
The Application of Hyaluronic Acid-Based Hydrogels in Bone and Cartilage Tissue Engineering
Published 2019-01-01“…Hyaluronic acid hydrogels have many advantages, such as promoting cell adhesion and proliferation and wound healing. …”
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23991
Layered energy equalization structure for series battery pack based on multiple optimal matching
Published 2025-04-01“…In addition, a fuzzy controller that can dynamically adjust the equalization current with the state parameter of the cell as the input condition is designed to optimize the equalization efficiency. …”
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23992
Efficacy of Larimichthys crocea TASOR protein-derived peptide FAM286 against Staphylococcus aureus
Published 2025-01-01“…The FAM286 could increase the permeability and disrupt the integrity of cell membranes. The cell showed aggregation phenomenon and entered the apoptosis stage. …”
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23993
Green hydrothermal synthesis of nickel and zinc-doped nickel ferrite nanoparticles using Dalbergiella welwitschii extracts and their biological studies
Published 2025-01-01“…The nanoparticles had high drug loading capacity (<10 %), promising cytotoxic activity against MCF-7 breast cancer cell lines and α-glucosidase inhibitory activities ranging between 5.6 and 13.4 μM comparable to standard drug acarbose (9.8 μM), respectively. …”
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23994
Microglial NLRP3-gasdermin D activation impairs blood-brain barrier integrity through interleukin-1β-independent neutrophil chemotaxis upon peripheral inflammation in mice
Published 2025-01-01“…Repeated intraperitoneal lipopolysaccharide administration causes NLRP3-dependent BBB permeabilization and myeloid cell infiltration into the brain. Using a mouse model with cell-specific hyperactivation of NLRP3, we identify microglial NLRP3 activation as essential for peripheral inflammation-induced BBB disruption. …”
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23995
A novel lncRNA AC112721.1 promotes the progression of triple-negative breast cancer by directly binding to THBS1 and regulating miR-491-5p/C2CD2L axis
Published 2024-12-01“…Loss- and gain-of-function experiments revealed that AC112721.1 significantly promoted cell proliferation and migration, suppressed cell apoptosis in vitro and inhibited tumorigenesis in vivo. …”
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23996
Uncoupling Protein 2 Increases Susceptibility to Lipopolysaccharide-Induced Acute Lung Injury in Mice
Published 2016-01-01“…On the other hand, LPS-induced alveolar epithelial cell death and inflammation were attenuated by genipin. …”
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23997
Developing an On‐Resin Synthesis of α‐Galactosylceramide‐Peptide Conjugate Vaccines
Published 2025-01-01“…Abstract The covalent attachment of peptide antigens to the NKT cell agonist, α‐galactosylceramide (αGalCer), generates self‐adjuvanting vaccines that prevent and/or eliminate disease in animal models of cancer and infectious disease. …”
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23998
A 3D-Printed Spherical Dual-Circular Polarized Luneburg Lens Antenna for Ku-Band
Published 2025-01-01“…To achieve the polarization conversion, the symmetry of the unit cell is disrupted. A 100 mm diameter lens is designed to operate at 12.6-17.1 GHz, fed by a low-profile dual-polarized magneto-electric dipole antenna. …”
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23999
Immobilization Technologies in Probiotic Food Production
Published 2013-01-01“…Subsequently, immobilization/encapsulation applications in the food industry aiming at the prolongation of cell viability are described together with an evaluation of their potential future impact, which is also highlighted and assessed.…”
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24000
Characterization of avian adenovirus FAdV-4/6/2009 isolate RABIES
Published 2018-04-01“…The virus was isolated in chicken Leghorn male hepatoma cell culture that exhibited cytopathogenic effect and identified as avian type С adenovirus by PCR followed by sequencing of hexon gene fragment. …”
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