Encapsulated human islets in alginate fiber maintain long-term functionality by Junko Nishida, Takahiro Tsuno, Shigeharu G. Yabe, Tatsuya Kin, Satsuki Fukuda, Fujie Takeda, Jun Shirakawa, Hitoshi Okochi

“…Encapsulated islets maintained C-peptide and glucagon secretion for more than 75 days in 5 cases; in two cases, their secretion was also successfully detected even on day 180. α- and β-cell composition and β-cell survival in islets were unaltered in the fiber after 75 or 180 days of culture. …”
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Comparative 3D ultrastructure of Plasmodium falciparum gametocytes by Felix Evers, Rona Roverts, Cas Boshoven, Mariska Kea-te Lindert, Julie M. J. Verhoef, Nico Sommerdijk, Robert E. Sinden, Anat Akiva, Taco W. A. Kooij

“…We also provide evidence for a gametocyte-specific cytostome, or cell mouth. Furthermore, we generate the first 3D reconstructions of the parasite’s endoplasmic reticulum (ER) and Golgi apparatus as well as gametocyte-induced extraparasitic structures in the infected red blood cell. …”
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Lymphocytes as an Indicator for Initial Kidney Function: A Single Center Analysis of Outcome after Alemtuzumab or Basiliximab Induction by Annemarie Weissenbacher, Theresa Hautz, Michael Kimelman, Rupert Oberhuber, Hanno Ulmer, Claudia Bösmüller, Manuel Maglione, Stefan Schneeberger

“…Alemtuzumab, an anti-CD52 T-cell and B-cell depleting monoclonal antibody, is established for induction therapy in renal transplantation (KTx). …”
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Q Fever: Current State of Knowledge and Perspectives of Research of a Neglected Zoonosis by Sarah Rebecca Porter, Guy Czaplicki, Jacques Mainil, Raphaël Guattéo, Claude Saegerman

“…Vaccination with inactive whole-cell bacteria has been performed and proved effective in humans and animals. …”
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The homeobox family gene signature predicts the prognosis of osteosarcoma and correlates with immune invasion by Wenda Liu, Kezhou Xia, Xinghan Huang, Zhun Wei, Zicheng Wei, Weichun Guo

“…Notably, HOXA1 overexpression suppressed osteosarcoma cell proliferation, migration, invasion, and tumor growth. …”
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Production of Palmitoleic and Linoleic Acid in Oleaginous and Nonoleaginous Yeast Biomass by Irena Kolouchová, Olga Maťátková, Karel Sigler, Jan Masák, Tomáš Řezanka

“…All yeast strains displayed high (70–90%) content of unsaturated fatty acids in total cell lipids. The content of dietary fatty acids of interest, namely, palmitoleic acid and linoleic acid, reached in Kluyveromyces and Trichosporon strains over 50% of total fatty acids and the highest yield, over 280 mg per g of dry cell weight of these fatty acids, was observed in Trichosporon with ammonium sulfate as nitrogen source at C/N ratio 70.…”
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De Novo Transcriptome Assembly and Differential Gene Expression Profiling of Three Capra hircus Skin Types during Anagen of the Hair Growth Cycle by Teng Xu, Xudong Guo, Hui Wang, Xiaoyuan Du, Xiaoyu Gao, Dongjun Liu

“…These genes mainly enriched in the functional cluster associated with cell cycle and cell division. The large contig catalogue as well as the genes which were differentially expressed in different skin types provide valuable candidates for further characterization of gene functions.…”
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High Throughput Approaches to Unravel the Mechanism of Action of a New Vanadium-Based Compound against Trypanosoma cruzi by M. Florencia Mosquillo, Pablo Smircich, Analía Lima, Sergio A. Gehrke, Gonzalo Scalese, Ignacio Machado, Dinorah Gambino, Beatriz Garat, Leticia Pérez-Díaz

“…We found a good IC50 value, (3.76 ± 0.08) μM, on CL Brener epimastigotes. The analysis of cell death mechanism allowed us to rule out the implication of a mechanism based on early apoptosis or necrosis. …”
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Clinicopathological, Histopathological, and Immunohistochemical Analysis of Mandibular Fibrosarcoma in a DSH Cat: A Case Report by Mahmood Ahmadi‐hamedani, Hamid Reza Moslemi, Sahar Ghaffari Khaligh, Mehdi Sedghi, Kimia Sattari

“…Before any therapeutic intervention, a cell blood count (CBC) test and FNA cytology were conducted. …”
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Preparation and Bioactivity Properties of a Novel Composite Membrane of Fructose Mediated β-Tricalcium Pyrophosphate/(Polyethylene Glycol/Chitosan) for Guided Tissue Regeneration by Jian-Wen Wang, Min-Hsiung Hon, Yi-Ming Kuo, Mei-Hui Chung

“…Cytotoxicity assay demonstrates that the composite membranes were nontoxic and had very good cell compatibility. Most importantly, the release of calcium ions and glucosamine from the composite membranes was proved to increase the cell proliferation of NIH3T3. …”
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L-Arginine Intake Effect on Adenine Nucleotide Metabolism in Rat Parenchymal and Reproductive Tissues by G. Kocic, J. Nikolic, T. Jevtovic-Stoimenov, D. Sokolovic, H. Kocic, T. Cvetkovic, D. Pavlovic, A. Cencic, D. Stojanovic

“…L-arginine is conditionally essetcial amino acid, required for normal cell growth, protein synthesis, ammonia detoxification, tissue growth and general performance, proposed in the treatment of men sterility and prevention of male impotence. …”
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Alterations in Monocyte CD16 in Association with Diabetes Complications by Danqing Min, Belinda Brooks, Jencia Wong, Robert Salomon, Wensheng Bao, Brian Harrisberg, Stephen M. Twigg, Dennis K. Yue, Susan V. McLennan

“…Monocytes express many cell surface markers indicative of their inflammatory and activation status. …”
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3D Segmentation and Visualization of Skin Vasculature Using Line-Field Confocal Optical Coherence Tomography by Oliver Mayer, Hanna Wirsching, Sophia Schlingmann, Julia Welzel, Sandra Schuh

“…The study’s results highlight the ability to visualize serpiginous, corkscrew-like, and irregular vessels across various skin cancers, including melanoma, squamous cell carcinoma, and basal cell carcinoma. These visualizations provide insights into vessel morphology, spatial arrangements, and blood flow patterns, which are crucial for assessing tumor growth and potential therapeutic responses. …”
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Multifaceted Assessment of Chronic Gastritis: A Study of Correlations between Serological, Endoscopic, and Histological Diagnostics by Toshitatsu Takao, Takeshi Ishikawa, Takashi Ando, Madoka Takao, Tsuguhiro Matsumoto, Yutaka Isozaki, Mika Okita, Yasuyuki Nagao, Hirokazu Oyamada, Keiichi Yokoyama, Atsushi Tatebe, Kazuhiko Uchiyama, Osamu Handa, Tomohisa Takagi, Nobuaki Yagi, Satoshi Kokura, Yuji Naito, Toshikazu Yoshikawa

“…Pepsinogen I/II ratio showed a significant correlation to the extent of mononuclear cell infiltration of the gastric corpus. When histological gastritis was divided, on the basis of the distribution of mononuclear cell infiltration, into gastritis limited to the antrum and corpus gastritis, these types were distinguished with high accuracy using a pepsinogen I/II ratio of 3 as the cutoff. …”
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A Comparative Genomic Study in Schizophrenic and in Bipolar Disorder Patients, Based on Microarray Expression Profiling Meta-Analysis by Marianthi Logotheti, Olga Papadodima, Nikolaos Venizelos, Aristotelis Chatziioannou, Fragiskos Kolisis

“…The aim of the study was to perform and interpret the results of a comparative genomic profiling study in schizophrenic patients as well as in healthy controls and in patients with bipolar disorder and try to relate and integrate our results with an aberrant amino acid transport through cell membranes. In particular we have focused on genes and mechanisms involved in amino acid transport through cell membranes from whole genome expression profiling data. …”
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Transforming Growth Factor Beta Family: Insight into the Role of Growth Factors in Regulation of Fracture Healing Biology and Potential Clinical Applications by Łukasz A. Poniatowski, Piotr Wojdasiewicz, Robert Gasik, Dariusz Szukiewicz

“…This process is a cascade of local and systemic phenomena spread over time, involving whole cell lineages and various cytokines and growth factors. …”
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Evaluation of the Cytotoxicity of Satureja spicigera and Its Main Compounds by Ahmad Reza Gohari, Seyed Nasser Ostad, Fahimeh Moradi-Afrapoli, Maryam Malmir, Shohreh Tavajohi, Hassan Akbari, Soodabeh Saeidnia

“…Other compounds did not show significant inhibition of the cell growth.…”
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Salmonella enteridis Septic Arthritis: A Report of Two Cases by Esat Uygur, Krishna Reddy, Feyza Ünlü Özkan, Salih Söylemez, Özlem Aydin, Serkan Şenol

“…It must be particularly kept in mind as an etiologic factor for the acute arthritis of a patient with sickle cell anemia and systemic lupus erythematosus. Clinicians should be cautious that the white blood cell count in synovial fluid can be under 50.000/mm3 in immune compromised individuals with septic arthritis. …”
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Unraveling the Anti-Cancer Mechanisms of Antibiotics: Current Insights, Controversies, and Future Perspectives by Nikolaos Nektarios Karamanolis, Dimitris Kounatidis, Natalia G. Vallianou, Krystalia Dimitriou, Eleni Tsaroucha, Georgios Tsioulos, Ioanna A. Anastasiou, Evangelos Mavrothalassitis, Irene Karampela, Maria Dalamaga

“…These mechanisms include the induction of apoptosis and cell cycle arrest, generation of reactive oxygen species, and inhibition of key regulators of cell proliferation and migration. …”
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Stryphnodendron adstringens have a modulatory effect on inflammatory cytokines markers of in vitro activated macrophages by Ivana Beatrice Mânica da Cruz, Cibele Ferreira Teixeira, Neida Luiza Pellenz, Moisés Henrique Mastella, Verônica Farina Azzolin, Euler Esteves Ribeiro, Fernanda Barbisan

“…This will be achieved using an in vitro protocol with the commercial macrophage cell line RAW 264.7. Methods: The macrophage inflammatory response was induced by the natural antigen phytohemagglutinin (PHA), with and without supplementation of different concentrations of S. adstringens extract. …”
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