Identification of Genes Regulating Gene Targeting by a High-Throughput Screening Approach by Fabien Delacôte, Christophe Perez, Valérie Guyot, Catherine Mikonio, Pierrick Potrel, Jean-Pierre Cabaniols, Christophe Delenda, Frédéric Pâques, Philippe Duchateau

“…However, there is still room for improvement, as even nuclease-induced HGT may vary in efficiency as a function of the nuclease, target site, and cell type considered. We have developed a high-throughput screening assay for the identification of factors stimulating meganuclease-induced HGT. …”
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DNA-encoded dynamic hydrogels for 3D bioprinted cartilage organoids by Ziyu Chen, Hao Zhang, Jingtao Huang, Weizong Weng, Zhen Geng, Mengmeng Li, Jiacan Su

“…This endows the hydrogels with viscoelasticity, printability, cell recognition, and stimuli responsiveness. This paper elaborates on strategies to encode bioink via DNA, emphasizing the regulation of predictable dynamic properties and the resulting interactions with cell behavior. …”
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Nutrition in patients with traumatic brain injury: Nutrition in patients with TBI by Stojanović Milena, Janković Radmilo, Ranđelović Milica, Vasilijić Milena, Nikolić Aleksandar, Radeka Jovan

“…After the initial injury, a cascade of events at the cellular and molecular level, including cell swelling, changes in cell membrane permeability, influx of immune or inflammatory mediators, and release of excitatory neurotransmitters result in so-called "secondary" brain damage. …”
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Propofol Reduces Lipopolysaccharide-Induced, NADPH Oxidase (NOX2) Mediated TNF-α and IL-6 Production in Macrophages by Tao Meng, Jingya Yu, Zhen Lei, Jianbo Wu, Shuqin Wang, Qiyu Bo, Xinyu Zhang, Zhiyong Ma, Jingui Yu

“…In present study, we used murine macrophage cell line RAW264.7 pretreated with propofol and stimulated with LPS. …”
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Syndecan-1 as a Mediator of Bacteria-Enterocyte Interactions by Michelle Henry-Stanley, Carol L. Wells

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НЕСКОЛЬКО СЛОВ О К.Н. ГРИНБЕРГЕ

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Nephrotic Syndrome Associated with Lung Cancer: A Rare Case of Malignancy Associated with AA Amyloidosis by Victor Gueutin, Anne-Lyse Langlois, Nathalie Shehwaro, Ryme Elharraqui, Philippe Rouvier, Hassane Izzedine

“…Although the association between renal cell carcinoma and systemic AA amyloidosis has been established, the evidence linking pulmonary cancer to AA amyloidosis is scarce. …”
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A Spherically Symmetric Model for the Tumor Growth by Saeed M. Ali, Ashfaque H. Bokhari, M. Yousuf, F. D. Zaman

“…The nonlinear tumor equation in spherical coordinates assuming that both the diffusivity and the killing rate are functions of concentration of tumor cell is studied. A complete classification with regard to the diffusivity and net killing rate is obtained using Lie symmetry analysis. …”
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An in vitro assessment of ionizing radiation impact on the efficacy of radiotherapy for breast cancer by Girgin Merve, Akat Ayberk, Akgül Büşra, Nalbant Nilgül, Karaçetin Didem, Abamor Emrah Şefik, Uğurel Osman Mutluhan, Turgut-Balik Dilek

“…It is possible to reduce the side effects of this effective treatment method and increase the chance of success by elucidating the responses it creates at the molecular level in the cell. This study aims to investigate of the molecular effects of therapeutic ionizing radiation on breast cancer, which is the most prevalent cancer type.…”
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Laser induced desorption and ablation: mechanism of metal removal from an Al-Cu-Fe alloy and a quasicrystal of the same composition by Mauro Satta, Haichen Liu, Xianglei Mao, Giuliano Moretti, Richard E. Russo, Anna Giardini, Aldo Mele

“…Their structures reduce to a single repeating unit like that of the unit cell of a crystal. The quasi-unitcell is representative of a cluster like structure where electrons cannot move with freedom as in metals. …”
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Prostate Cancer in a Male with Holt-Oram Syndrome: First Clinical Association of the TBX5 Mutation by Noel J. Aherne, Guhan Rangaswamy, Pierre Thirion

“…TBX5 is part of the T-box gene family and is thought to upregulate tumour cell proliferation and metastasis when mutated. We report the first clinical case of prostate cancer in an individual with Holt Oram syndrome.…”
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Corneal Cross-linking for Keratoconus: Exploring the Issues Regarding Accelerated Protocols and Thin Corneas by Farhad Hafezi

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Nonalcoholic Fatty Liver Disease: Its Mechanisms and Complications by Abdelfattah El Ouaamari, Kaori Minehira

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MINERALOGY OF THE VORONTSOVSKOE GOLD DEPOSIT (NORTHERN URALS). PART 2: NATIVE ELEMENTS, SULFIDES, ARSENIDES, TELLURIDES by A.V. Kasatkin, S.Yu. Stepanov, M.V. Tsyganko, R. Škoda, F. Nestola, J. Plášil, E. Makovicky, A.A. Agakhanov, R.S. Palamarchuk

“…The paper reports on native elements, sulfides, arsenides and tellurides discovered at the deposit, their chemical compositions, as well as unit-cell parameters and optical properties of some minerals. …”
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Complete Disappearance of Lung Abnormalities on High-Resolution Computed Tomography: A Case of Histiocytosis X by Sergio Negrin-Dastis, Dominique Butenda, Jacques Dorzee, Jacques Fastrez, Jean-Paul d’Odémont

“…A case of pulmonary Langerhans cell histiocytosis, proved by both lung high-resolution computed tomography and lung biopsy, is described. …”
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Discovering CRISPR-Cas system with self-processing pre-crRNA capability by foundation models by Wenhui Li, Xianyue Jiang, Wuke Wang, Liya Hou, Runze Cai, Yongqian Li, Qiuxi Gu, Qinchang Chen, Peixiang Ma, Jin Tang, Menghao Guo, Guohui Chuai, Xingxu Huang, Jun Zhang, Qi Liu

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Development and validation of a nomogram to predict survival in septic patients with heart failure in the intensive care unit by Tong Tong, Yikun Guo, Qingqing Wang, Xiaoning Sun, Ziyi Sun, Yuhan Yang, Xiaoxiao Zhang, Kuiwu Yao

“…A nomogram model was developed to predict short-term survival probabilities, using 13 variables: age, pneumonia, endotracheal intubation, mechanical ventilation, potassium (K), anion gap (AG), lactate (Lac), activated partial thromboplastin time (APTT), white blood cell count (WBC), red cell distribution width (RDW), hemoglobin-to-red cell distribution width ratio (HRR), Sequential Organ Failure Assessment (SOFA) score, and Charlson Comorbidity Index (CCI). …”
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Potential toxic elements in surface water of Mokosh Beel, Gazipur, Bangladesh: Ecological and human health risk assessment for recreational users by Md. Shahriar Mahmud, M. Safiur Rahman, S.A. Dina, M. Rifat Nasher, Tasrina R. Choudhury, Bilkis A. Begum, Abdus Samad

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Artificial intelligence-driven identification and mechanistic exploration of synergistic anti-breast cancer compound combinations from Prunella vulgaris L.-Taraxacum mongolicum Han... by Chunlai Feng, Jiaxi Cheng, Mengqiu Sun, Chunxue Qiao, Qiuqi Feng, Naying Fang, Yingying Ge, Mengjie Rui

“…The bioinformatics analysis revealed that these compounds could regulate tumor-related pathways synergistically, inhibiting tumor cell growth, inducing cell apoptosis, and blocking cell cycle progression. …”
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Microplastics: A threat to Fetoplacental unit and Reproductive systems by Abass Toba Anifowoshe, Md Noor Akhtar, Abisola Majeed, Asem Sanjit Singh, Toyyibah Funmilayo Ismail, Upendra Nongthomba

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