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23521
Novel position reconstruction methods for highly granular electromagnetic calorimeters
Published 2024-01-01“…We find that lwk-means is unable to effectively use calorimeter transverse cell sizes smaller than 2 mm. New reconstruction methods for highly granular designs are developed. …”
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23522
The influence of infectious diseases on population genetics
Published 2006-04-01“…Motivated by the known influenceof sickle-cell anemia on the morbidity and mortality ofmalaria-infected humans, we study the effect of malaria on the genetic composition of a host (human) population where sickle-cell anemia is prevalent and malaria is endemic. …”
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23523
A Study of Epstein-Barr Virus BRLF1 Activity in a Drosophila Model System
Published 2012-01-01“…BRLF1 and BZLF1 function as transcription factors for viral transcription and are also potent modifiers of host cell activity. Here we have used our model systems to identify host cell genes whose proteins modulate BRLF1 and BZLF1 functions. …”
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23524
Diversity in the Regulation of Autophagy and Mitophagy: Lessons from Parkinson's Disease
Published 2011-01-01“…Complete clearance of mitochondria can be observed during normal maturation of certain mammalian cell types, and during certain forms of neuronal cell death. …”
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23525
Dynamic Crushing Analysis of Hexagonal-Kagome Combined Honeycomb with Negative Poisson’s Ratio
Published 2022-01-01“…In this study, a novel design was proposed by combining various cell elements to obtain better crashworthiness, providing a new concept to promote the development of lightweight materials.…”
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23526
Desmoplastic reaction in the microenvironment of head and neck and other solid tumors: the therapeutic barrier
Published 2025-02-01“…Head and neck squamous cell carcinoma (HNSCC) remains a challenge due to limited prognostic biomarkers and therapeutic options. …”
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23527
Inhibitory Effects of Antimicrobial Peptides on Lipopolysaccharide-Induced Inflammation
Published 2015-01-01“…On the one hand, AMPs can readily penetrate the cell wall barrier by neutralizing LPS to remove Gram-negative bacteria that can lead to infection. …”
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23528
A Review on the Application of PD-1 Blockade in EBV-Associated Nasopharyngeal Carcinoma Immunotherapy
Published 2022-01-01“…Immune checkpoint blockade therapy targeting the programmed cell death-1 (PD-1) and programmed cell death ligand-1 (PD-L 1) receptors have shown efficacy in early phase I clinical trials, with ongoing phase III clinical trials. …”
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23529
L’intercompréhension : un nouveau souffle pour les langues romanes minoritaires et pour les dialectes ?
Published 2016-06-01“…Une démarche qui pourrait inclure des langues mineures et régionales de la même famille, afin d’exploiter les richesses de celles-ci et leur donner une forme de légitimité. …”
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23530
Genetic Factors in Animal Models of Intestinal Inflammation
Published 1995-01-01“…Inbred Lewis rats challenged by purified bacterial cell wall polymers, indomethacin or small bowel bacterial overgrowth develop chronic granulomatous intestinal inflammation with fibrosis and extraintestinal manifestations, whereas Fischer (major histocompatibility complex identical to Lewis) and Buffalo rats identically stimulated demonstrate only self-limited enterocolitis with no chronic inflammation, fibrosis, granulomas or extraintestinal inflammation. …”
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23531
Neoadjuvant anti-PD-1-based immunotherapy: evolving a new standard of care
Published 2025-01-01“…Neoadjuvant (presurgical) anti-programmed cell death protein-1 (PD-1)-based immunotherapy as a new approach to cancer treatment has been developing on an accelerated trajectory since the seminal clinical trial results from studies in lung cancer and melanoma were published in 2018. …”
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23532
Prolonged Pediatric Extracorporeal Membrane Oxygenation Support with Cardiopulmonary Failure in Juvenile Myelomonocytic Leukemia
Published 2020-01-01“…However, these patients are at increased risk for early death secondary to pulmonary complications due to leukostasis, direct pulmonary infiltration with WBC, and systemic inflammatory response syndrome following malignant cell lysis. Despite the high risk of complications, ECMO support must be discussed as part of management, providing better outcome in this group of patients.…”
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23533
Midas- oder: Die Auferstehung des Fleisches von Wolfgang Jeschke
Published 2014-12-01“…Midas oder: Die Auferstehung des Fleisches de Wolfgang Jeschke a obtenu le Prix Kurd-Lasswitz dans deux catégories, celle du meilleur roman de science-fiction et, sur le même thème, celle de la meilleure pièce radiophonique : le roman fut récompensé en 1990 ; en 1992, c’est Hermann Motschach qui fut distingué pour sa pièce éponyme. …”
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23534
Autologous Cord Blood Therapy for Infantile Cerebral Palsy: From Bench to Bedside
Published 2014-01-01“…This review will focus on recent developments in cell therapy for infantile cerebral palsy by transplantation of autologous umbilical cord blood. …”
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23535
Candida Biofilms and the Host: Models and New Concepts for Eradication
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23536
Glutamate Receptors in Neuroinflammatory Demyelinating Disease
Published 2006-01-01“…The condition predominantly affects young adults and is characterised by immunological and inflammatory changes in the periphery and CNS that contribute to neurovascular disruption, haemopoietic cell invasion of target tissues, and demyelination of nerve fibres which culminate in neurological deficits that relapse and remit or are progressive. …”
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23537
PPAR𝜸 and Oxidative Stress: Con(𝜷) Catenating NRF2 and FOXO
Published 2012-01-01“…Recent experimental pieces of evidence demonstrate that PPARγ is implicated in the oxidative stress response, an imbalance between antithetic prooxidation and antioxidation forces that may lead the cell to apoptotic or necrotic death. In this delicate and intricate game of equilibrium, PPARγ stands out as a central player devoted to the quenching and containment of the damage and to foster cell survival. …”
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23538
Mimicking Myelodysplastic Syndrome: Importance of Differential Diagnosis
Published 2021-01-01“…Copper deficiency is a rare nutritional deficiency with hematological manifestations that mimic those found in myelodysplastic syndrome, a hematological malignancy incurable without allogeneic hematopoietic stem cell transplantation. Bone marrow biopsy findings and peripheral blood counts are oftentimes insufficient to differentiate the two conditions. …”
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23539
Feedback bit allocation in distributed antenna array systems
Published 2020-11-01“…In a frequency division duplex communication system,precoding at the base station usually requires terminal feedback channel state information.In a distributed array system,the channel conditions between the terminal and different access nodes in the cell are different because multiple access nodes are arranged at different locations in the cell.When the resources for feedback channel state information are limited,the allocation method of feedback bit needs to be optimized to improve the overall performance of the system.In a multi-user distributed array system,an access node selection method based on distance threshold was adopted.Based on this method,the quantization characteristics of the random vector quantization codebook and the Taylor expansion method were used to derive the system quantization capacity loss,and then an approximate expression was given.Based on this expression,a feedback bit allocation method was proposed.Compared with other allocation methods,the method of this paper was more universal because it did not limit the number of access nodes selected by the user.The simulation results show that the strategy proposed is superior to the traditional equal-bit allocation scheme and can obtain better performance when the feedback resources are limited.…”
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23540
Influencing immunity: role of extracellular vesicles in tumor immune checkpoint dynamics
Published 2024-11-01“…Extracellular vesicles (EVs), which are pivotal mediators of cell–cell communication, have been extensively studied and found to play key roles in the functionality of ICPs. …”
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