Entretien avec Claude Yersin, Alain Libolt et Christian Cloarec by Jean-Michel Déprats

“…Quatre mises en scène seront ainsi évoquées au cours de ces deux journées, soit dans l’ordre chronologique : la mise en scène en langue anglaise de Stéphane Braunschweig créée au cinquantième Festival Officiel d’Édimbourg en 1997 reprise en tournée notamment en France au Théâtre des Amandiers de Nanterre, la mise en scène en langue française de Claude Yersin créée à Angers en 1998 au Nouveau Théâtre d’Angers (Centre Dramatique National) reprise à Paris au Théâtre de l’Est Parisien, celle en langue française toujours de Jacques Nichet au Théâtre National de Toulouse en 2002, et celle, en français également, de Jean-Yves Ruf à la Maison de la Culture de Bobigny en 2008.…”
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Development of a Car Battery Monitoring System. by Dusabimana Abel

“…The BMS performs these tasks by integrating one or more of the functions, such as protecting the cell, controlling the charge, determining the state of charge (SOC), the state of health (SOH), and the remaining useful life (RUL) of the battery, cell balancing, as well as monitoring and storing historical data.The purpose of battery level monitoring system is to measure and monitor the fundamental parameters of a rechargeable battery. …”
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Endobronchial Infection and Bacterial Lymphadenitis by Gemella morbillorum Leading to Airway Perforation and a Bronchopleural Fistula by Kaitlin N. DePrez, John Ferguson

“…Conclusion: In cases of severe mediastinal adenopathy in a young patient, bacterial lymphadenitis should be considered in the differential diagnosis with lymphoma, germ cell tumor, granulomatosis with polyangiitis, sarcoidosis, histoplasmosis, and inflammatory myofibroblastic tumor.…”
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Elucidating metabolite and pH variations in stroke through guanidino, amine and amide CEST MRI: A comparative multi-field study at 9.4T and 3T by Kexin Wang, Licheng Ju, Guanda Qiao, Yajie Liang, Yihan Wu, Chengyan Chu, Joshua Rogers, Yuguo Li, Suyi Cao, Valina L. Dawson, Ted M Dawson, Piotr Walczak, Jiadi Xu

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The Utility of Thiopurine Methyltransferase Enzyme Testing in Inflammatory Bowel Disease by Laura Chisick, Curtis Oleschuk, Charles N Bernstein

“…OBJECTIVE: To assess the levels of red blood cell thiopurine methyltransferase (TPMT) in subjects with inflammatory bowel disease (IBD) and to determine how these levels impacted thiopurine dosing and leukopenia over the first six months of therapy.…”
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Neoadjuvant atezolizumab + chemotherapy for resectable NSCLC: 3-year clinical update of phase II clinical trial results and translational findings by Benjamin Izar, Justin F Gainor, Mark M Awad, Codruta Chiuzan, Anjali Saqi, Catherine A Shu, Katja Schulze, Brian S Henick, Naiyer A Rizvi, Samyukta Mallick, Yohanna Georgis, Peter D Koch, Stephanie Izard, Robert F Garofano, Cheryl V Wong, Jessica Grindheim, Joshua R Sonett, Alison M Taylor

“…Introduction Neoadjuvant chemoimmunotherapy has achieved overall survival (OS) benefit for patients with resectable non-small cell lung cancer (NSCLC). Here, we present outcomes after 3 years of follow-up from the first reported study of neoadjuvant atezolizumab+chemotherapy.Methods This open-label, multicenter single-arm investigator-initiated phase II study conducted at three US hospitals tested up to four cycles of atezolizumab, carboplatin, and nab-paclitaxel prior to surgery. …”
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An antibody cocktail targeting two different CD73 epitopes enhances enzyme inhibition and tumor control by Jin-Gen Xu, Shi Chen, Yang He, Xi Zhu, Yanting Wang, Zhifeng Ye, Jin Chuan Zhou, Xuanhui Wu, Lei Zhang, Xiaochen Ren, Huifeng Jia, Haijia Yu, Xiaoyue Wei, Yujie Feng, Xiaofang Chen, Xiaopei Cui, Xianfei Pan, Shaojie Wang, Simin Xia, Hongjie Shang, Yueqing Pu, Wei Xu, Haidong Li, Qian Chen, Zeyu Chen, Manfu Wang, Xiaodong Yan, Hui Shi, Mingwei Li, Yisui Xia, Roberto Bellelli, Shunli Dong, Jun He, Jun Huang, Chen-Leng Cai, Xiangyang Zhu, Yifan Zhan, Li Wan

“…The cocktail not only harnesses the advantages of its parental mAbs in enzyme inhibition but also shows a significantly greater capability of promoting T cell proliferation in vitro. Structural analyses show that HB0045 effectively locks the CD73 dimer in a “partially open” non-active conformation through a double lock mechanism. …”
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Effects of methotrexate upon inflammatory parameters induced by carrageenan in the mouse model of pleurisy by Eduardo Monguilhott Dalmarco, Tânia Silvia Fröde, Yara Santos Medeiros

“…Background: The model of pleurisy induced by carrageenan exhibits a biphasic response (4 and 48 h) and permits the quantification of exudate, cell migration and certain enzymes such as myeloperoxidase (MPO) and adenosine-deaminase (ADA) that are markers of activated leukocytes.…”
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Sepsis due to Erysipelothrix rhusiopathiae in a Patient with Chronic Lymphocytic Leukemia Associated with Bronchopneumonia due to PSeudomonas aeruginosa And Escherichia coli: A Cas... by Victoria Bîrlutiu

“…INTRODUCTION: The present report describes a case of sepsis due to Erysipelothrix rhusiopathiae in a patient with B-cell chronic lymphocytic leukemia with no animal exposure, associated with concomitant bronchopneumonia due to Pseudomonas aeruginosa and Escherichia coli.…”
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Bacterial Meningitis in the Absence of Cerebrospinal Fluid Pleocytosis: A Case Report and Review of the Literature by Ryota Hase, Naoto Hosokawa, Makito Yaegashi, Kiyoharu Muranaka

“…Elevation of cerebrospinal fluid (CSF) cell count is a key sign in the diagnosis of bacterial meningitis. …”
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Current developments in personalized treatment strategies for elderly acute myelogenous leukemia patients by Xueting Hou, Jizhang Bao

“…Acute myelogenous leukemia(AML) is a life-threatening hematologic malignancy that predominantly affects the elderly.Currently, chemotherapy and hematopoietic stem cell transplantation are the primary treatment modalities for AML, though their clinical application is limited in older patients.Recent years have seen the development of novel molecular targeted therapies, such as isocitrate dehydrogenase 1/2 (IDH1/2) and Feline macrophage stimulator-like tyrosine kinase 3 (FLT3) inhibitors, as well as individualized approaches like chimeric antigen receptor T-cell (CAR-T) therapy.However, due to patient heterogeneity and drug resistance, treatment outcomes for elderly AML remain unsatisfactory, underscoring the need for more precise and safer individualized treatment strategies.The combination of chemotherapy with novel targeted or immunotherapies shows promise as a future treatment direction.This research reviews the latest advances in the treatment of elderly AML, with a focus on achieving more individualized and safer therapeutic approaches.…”
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Role of copper homeostasis and cuproptosis in heart failure pathogenesis: implications for therapeutic strategies by Zhichao Liu, Yongkang Gan, Zhen Shen, Siqi Cai, Xizhen Wang, Yong Li, Xiaofeng Li, Huanjie Fu, Jinhong Chen, Ningcen Li

“…Recently, a new type of copper-dependent cell death known as cuproptosis has drawn increasing attention to the impact of copper dyshomeostasis on HF. …”
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Clinical forms of 5 cases of circumcised penile cancer in immunocompetent subjects in Abidjan (Ivory Coast) by Evrard Kouame Yao, Abraham Hognou Yao, Donafologo Daouda Yeo, Tawakaltu Adebayo, Michel Tuo, Freddy Junior Zouan, Noel Coulibaly

“…The last case was a metastatic squamous cell carcinoma of the penis in a 68-year-old patient. …”
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The Clinical Understaging of Recurrent Glottic Carcinoma after Radiation Failure by Moustafa Mourad, Sami P. Moubayed, Ilya Likhterov, Mark Urken

“…Recurrent glottic squamous cell carcinomas following radiation therapy for early staged tumors are oftentime early staged tumors. …”
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RETRACTED ARTICLE: Functionalized graphene oxide nanosheets with folic acid and silk fibroin as a novel nanobiocomposite for biomedical applications by Reza Eivazzadeh-Keihan, Farkhondeh Alimirzaloo, Hooman Aghamirza Moghim Aliabadi, Ehsan Bahojb Noruzi, Ali Reza Akbarzadeh, Ali Maleki, Hamid Madanchi, Mohammad Mahdavi

“…The cell viability percentages were 96.67, 96.35 and 97.23% for 24, 48, and 72 h, respectively, and its hemolytic effect was less than 10%. …”
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Vaginal Microbial Environment Skews Macrophage Polarization and Contributes to Cervical Cancer Development by Guannan Zhou, Fangyue Zhou, Yuanyuan Gu, Menglei Zhang, Ganrong Zhang, Fang Shen, Keqin Hua, Jingxin Ding

“…Functional assays, including cell proliferation assay, tube formation assay, and immunofluorescence staining, revealed the effect of Peptostreptococcus anaerobius-treated macrophages on cell proliferation and the angiogenesis process. …”
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Perspectives in HPV Secondary Screening and Personalized Therapy Basing on Our Understanding of HPV-Related Carcinogenesis Pathways by Aleksander Celewicz, Marta Celewicz, Michał Michalczyk, Rafał Rzepka

“…This review follows HPV-related changes in infected cell biology to point what potential markers and targets for therapy are in option when dealing with HPV-related diseases.…”
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Therapeutic effects of epigallocatechin and epigallocatechin gallate on the allergic reaction of αs1-casein sensitized mice by Qianqian Zhang, Xiaofeng Yu, Linghan Tian, Yanjun Cong, Linfeng Li

“…The results showed that both EGC and EGCG significantly reduced levels of mast cell protease, histamine, specific IgE antibodies, and Th2 cytokines in allergic mice. …”
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Advanced Role of Neutrophils in Common Respiratory Diseases by Jinping Liu, Zhiqiang Pang, Guoqiang Wang, Xuewa Guan, Keyong Fang, Ziyan Wang, Fang Wang

“…They participate in the clearance of exogenous pathogens and endogenous cell debris and play an essential role in the pathogenesis of many respiratory diseases. …”
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Malignant Transformation Six Months after Removal of Intracranial Epidermoid Cyst: A Case Report by Fayçal Lakhdar, El Mehdi Hakkou, Rachid Gana, Rachid My Maaqili, Fouad Bellakhdar

“…We report a case of squamous cell carcinoma arising in the cerebellopontine angle. …”
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