TIGIT inhibitor M6223 as monotherapy or in combination with bintrafusp alfa in patients with advanced solid tumors: a first-in-human, phase 1, dose-escalation trial by Wei Gao, Ping Hu, Aung Naing, Meredith McKean, Anthony Tolcher, Lillian L Siu, Keyvan Tadjalli-Mehr, Anja Victor, Emilia Richter, Marco A F Nogueira Filho, Thomas Kitzing, Stephan Gleicher, Daniel Holland

“…Background M6223 is an intravenous (IV), Fc-competent, fully human, antagonistic, anti-T cell immunoreceptor with immunoglobulin and immunoreceptor tyrosine-based inhibitory motif domains (TIGIT) antibody. …”
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Giardiose et oesophagostomose nodulaire au parc national de Taï : risque zoonotique ? by Roland Wa Yao Kouassi, William Scott McGraw, Bassirou Bonfoh, Julie Brunet, Sylvie Perroteye, Ermanno Candofi, Eliezer Kouakou N’goran

“…Parallèlement, le gène de la TPI a été identifié dans 63 % des selles humaines et 43 % des selles de singes et le gène de la Gdh détecté dans 37 % des selles humaines et 87 % de celles des singes. Par ailleurs, des œufs d’Oesophagostomum ont été observés au microscope dans 10 % des selles humaines et 32 % des prélèvements simiens. …”
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Hubungan Karakteristik Penderita dengan Gambaran Sitopatologi pada Kasus Karsinoma Paru yang Dirawat di RSUP Dr. M. Djamil Padang by Metha Arsilita Hulma, Masrul Basyar, Henny Mulyani

“…Results of univariate analysis showed patients with lung carcinoma mostly are male (71.1%), > 40 years age group (85.2%), background in basic educated people (49.2 %), had occupation contacted carcinogenic compound (53,9%), the greatest frequency was found in patients with severe Brikman Index (49.2%), active smokers (66.4%), and most of cytopathology cell type are adenocarcinoma (47.7 %). Results of bivariate analysis showed there are significant relationship between sex and smoking history with the overview of cytopathology (p=0,022 dan p=0,000). …”
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Comprehensive analysis of full genome sequence and Bd-milRNA/target mRNAs to discover the mechanism of hypovirulence in Botryosphaeria dothidea strains on pear infection with BdCV1... by Wangcheng Hu, Hui Luo, Yuekun Yang, Qiong Wang, Ni Hong, Guoping Wang, Aiming Wang, Liping Wang

“…WEGO analysis revealed involvement of the differentially expressed Bd-milRNA-targeted genes in metabolic process, catalytic activity, cell process and response to stress or stimulus. …”
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Clinicopathological and molecular characteristics of papillary thyroid carcinoma in adolescent and young adult patients by Van Phu Thang Nguyen, Hirokazu Kurohama, Yuko Akazawa, Thi Ngoc Anh Nguyen, Katsuya Matsuda, Yuki Matsuoka, Zhanna Mussazhanova, Kenichi Yokota, Shinya Satoh, Hiroyuki Yamashita, Thi Nhung Nguyen, Yerkerzhan Sailaubekova, Masahiro Nakashima

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Biological Characteristics and Whole-Genome Analysis of a Porcine <i>E. coli</i> Phage by Shenghui Wan, Nana Li, Sajid Habib, Pei Zheng, Yanfang Li, Yan Liang, Yonggang Qu

“…The optimal MOI for phage Psq-1 was 0.1, with a latent period of 25 min, an exponential growth period of 25 min, and a lysis yield of 44.21 PFU/cell. Its activity remains stable at temperatures between 40 °C and 60 °C and from pH 4.0 to pH 13.0. …”
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Polyethylene microplastic exposure adversely affects oocyte quality in human and mouse by Qiaoling Wang, Fengli Chi, Yingdong Liu, Qiurong Chang, Siyu Chen, Pengcheng Kong, Wanli Yang, Wenqiang Liu, Xiaoming Teng, Yan Zhao, Yi Guo

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Correction: Cancer care in German centers of excellence during the first 2 years of the COVID-19 pandemic by Volker Arndt, Daniela Doege, Stefan Fröhling, Peter Albers, Hana Algül, Ralf Bargou, Carsten Bokemeyer, Martin Bornhäuser, Christian H. Brandts, Peter Brossart, Sara Yvonne Brucker, Tim H. Brümmendorf, Hartmut Döhner, Norbert Gattermann, Michael Hallek, Volker Heinemann, Ulrich Keilholz, Thomas Kindler, Cornelia von Levetzow, Florian Lordick, Ulf Peter Neumann, Christoph Peters, Dirk Schadendorf, Stephan Stilgenbauer, Thomas Zander, Daniel Zips, Delia Braun, Thomas Seufferlein, Gerd Nettekoven, Michael Baumann

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Impact of mango peel pectin and Bacillus iranensis on growth, immunity, and gene expression in Nile tilapia (Oreochromis niloticus) by Anisa Rilla Lubis, Nguyen Vu Linh, Khambou Tayyamath, Supreya Wannavijit, Punika Ninyamasiri, Chanagun Chitmanat, Wanaporn Tapingkae, Einar Ringø, Hien Van Doan, Maria Ángeles Esteban

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Growth performance of 7-g Anguilla bicolor bicolor at different density by Eko Harianto, Tatag Budiardi, Agus Oman Sudrajat

“…Blood profile in form of hemoglobin, hematocrit, red blood cell and differential leukocytes showed no significant differences except for the leukocyte parameters with the highest rate was achieved at the stocking density of 4 g/L (2.70±0.001x105 sel/mm3). …”
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Role of Positron Emission Tomography-Computed Tomography Scan in Reaching Definite Diagnosis in Patients With Fever of Unknown Origin and Inflammation of Unknown Origin in Rheumato... by Koreli UY, Torun ES, Adaş M

“…Diagnoses were ankylosing spondylitis (n=4), rheumatoid arthritis (n=1), systemic lupus erythematosus (n=3), giant cell arteritis (n=1), adult onset Still disease (n=1), undifferentiated connective tissue disease (n=1), undifferentiated vasculitis (n=1) and crystal arthropathy (n=1), Hodgkin lymphoma (n=1) and cryptococcosis (n=1). …”
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<i>Bacillus cabrialesii</i> subsp. <i>cabrialesii</i> Strain TE5: A Promising Biological Control Bacterium Against the Causal Agent of Spot Blotch in Wheat by Ixchel Campos-Avelar, Michelle Fabiela García Jaime, Pamela Helué Morales Sandoval, Fannie Isela Parra-Cota, Sergio de los Santos Villalobos

“…Moreover, the antifungal activity of strain TE5 and its cell-free extract (CFE) was evaluated against <i>Bipolaris sorokiniana</i>, an emergent wheat pathogen. …”
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The mediating role of accelerated biological aging in the association between household air pollution from solid cooking fuels and neuropsychiatric disorders by Rui Tang, Haisheng Wu, Ling Jiang, Jie Zhou, Xia Gao, Jiazhen Zheng, Ya-Ping Tang, Mingxi Tang

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A karyomorphological study on Actaea acuminata, A. asiatica, and A. erythrocarpa (Ranunculaceae) by Elizaveta Yu. Mitrenina, Andrey S. Erst, Denis A. Krivenko, Tatiana N. Veklich, Tatiana V. Leonova, Olga A. Chernyagina, Valentin V. Yakubov, Kunli Xiang, Yuan-Yuan Ling, Wei Wang

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Fabrication of Nano-Silver Composite Using Amomum longiligulare Fruit Polysaccharides and Their Biological Activities by Lian Y, Ma N, Cheng Q, Luo M, Xu Z, He F, Zhou X, Zhang Y, Jin D, Kong Y, Wang Y, Wei N

“…The IC50 values of ALP(D)-AgNPs on the MDA-MB-231, HepG2, Caco-2, and C6 cancer cell lines were 14.72 ± 0.23, 8.19 ± 0.65, 22.73 ± 3.01, and 15.77 ± 2.91 μg/mL, respectively.Conclusion: In summary, we have identified a novel material for the green synthesis of silver nanoparticles. …”
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Upper circumpolar deep water influences microbial functional gene composition and diversity along the southern Central Indian Ridge and eastern Southwest Indian Ridge by Sheryl Oliveira Fernandes, Dhiraj Paul, Surya Prakash Lankalapalli, Srinivas Rao Arvapalli, Vidya PJ, John Kurian Palayil

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Otodectes cynotis (Acari: Psoroptidae) infestations in Southern pudus (Pudu puda): In situ and ex situ data of an unexpected host-parasite record by Caroline Wilhelm, Edwin Kniha, Pamela Muñoz, Ángelo Espinoza, Laura Platner, Saskia Dreyer, Lisa Grund, Zoë Tess Lara Lindhorst, Ulrich Gärtner, Julia Walochnik, Anja Taubert, Dominik Fischer, Stephan Hering-Hagenbeck, Carlos Hermosilla, David Ebmer

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Characterization of β-Actin Promoter from Nile Tilapia (Oreochromis niloticus) by . Alimuddin, A. Octavera, O.Z. Arifin, K. Sumantadinata

“…The construct was microinjected into one-cell stage of zebrafish (Danio rerio) embryos to test the tiBP promoter activity. …”
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Cardiovascular disease attenuates the protective effect of folate on global cognitive function in an elderly population: a cross-sectional study by Jianqiang Zhang, Di Yue, Huifeng Zhang

“…However, there is a lack of systematic research on the association of dietary intake of folate and serum, and red blood cell (RBC) folate levels with global cognitive impairment (CoI) in the elderly population. …”
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Korelasi Kadar Hemoglobin dengan Kadar Nitric Oxide pada Preeklamsia dan Kehamilan Normal by Siska Helina, Ariadi , Delmi Sulastri

“…<br />Kata kunci:  hemoglobin, nitric oxide, preeklamsia, kehamilan normal</p><p> </p><p>Abstract <br />Endothelial cell activation or dysfunction becomes a major factor pathogenesis of preeclampsia. …”
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