Des langues en littérature. Aperçu et apport d'un florilège hétéroglossique by Rémy Porquier

“…Une partie de ces textes soulèvent deux questions : celle de la représentation écrite des interactions orales exolingues et celle de leur traduction. …”
Get full text

TLRs, Alcohol, HCV, and Tumorigenesis by Keigo Machida

“…Recent studies of HCC have centered on cancer-initiating stem cell (CSC), including detection of CSC in cancer, identification of CSC markers, and isolation of CSC from human HCC cell lines. …”
Get full text

Expression of WW Domain-Containing Oxidoreductase WOX1 in Human Nervous System Tumors by Ming-Fu Chiang, Shur-Tzu Chen, Chen-Peng Lo, Chun-I Sze, Nan-Shan Chang, Yu-Jen Chen

Get full text

Homogeneous magnetic flux in Rydberg lattices by J. Eix, R. Bai, T. Lahaye, A. Browaeys, H. P. Büchler, S. Weber

“…Remarkably, the total flux within a magnetic unit cell directly depends on the ratio of the number of lattice sites to ancilla atoms, making it topologically protected to small changes in the positions of the atoms. …”
Get full text

CRLH Transmission Lines for Telecommunications: Fast and Effective Modeling by Juanjuan Gao, Guizhen Lu

“…The parameter extraction procedure is provided and validated by T-type unit cell model. The responses of distributed prototype and extracted equivalent LC circuit model are in good agreement. …”
Get full text

Role of Neutrophil Apoptosis in the Resolution of Inflammation by Driss El Kebir, János G. Filep

Get full text

Hepatitis B and Hepatitis C Viral Infections in Patients with Chronic Lymphocytic Leukemia by Gerald Y Minuk, Betty Lerner, Spencer B Gibson, James B Johnston, Julia Uhanova, Anton Andonov, Jun Wu

Get full text

Adhered macrophages as an additional marker of cardiomyocyte injury in biopsies of patients with dilated cardiomyopathy by Warmusz Oliwia, Badziński Arkadiusz, Reichman-Warmusz Edyta, Dudek Damian, Wojnicz Romuald

Get full text

Role of PPAR𝛼 in Hepatic Carbohydrate Metabolism by Annelies Peeters, Myriam Baes

Get full text

Immune Checkpoint Inhibitor Therapy for Bone Metastases: Specific Microenvironment and Current Situation by Chang Liu, Miao Wang, Changli Xu, Bo Li, Juxiang Chen, Jianchun Chen, Zhiwei Wang

“…On this basis, we expounded the clinical application of immune checkpoint inhibitors for bone metastasis of common tumors, including non-small-cell lung cancer, renal cell carcinoma, prostate cancer, melanoma, and breast cancer. …”
Get full text

Anatomical, functional, and blood-born predictors of severity of brachycephalic obstructive airway syndrome severity in French Bulldogs by Claudia Schmid, Claudia Schmid, Claudia Schmid, Aline R. Steiner, Léonie Spielhofer, Léonie Spielhofer, Meltem Galfetti, Meltem Galfetti, Nikki Rentsch, Nikolay Bogdanov, Johannes Vogel, Regina Hofmann-Lehmann, Regina Hofmann-Lehmann, Sonja Hartnack, Georgy Astakhov, Reinhard Furrer, Anna Bogdanova, Anna Bogdanova, Iris Margaret Reichler

Get full text

Case report: JAK inhibitor treatment of immune dysregulation symptoms in a patient with PTPN2 deficiency by Anna Roppelt, Ulyana Markina, Irina Beloglazova, Irina Beloglazova, Vasily Parshin, Dmitry Kanner, Dmitry Pershin, Mariia Fadeeva, Elena Raykina, Maxim Aleksenko, Alexander Karaulov, Mariana Lysenko, Mariana Lysenko, Daria Fomina, Daria Fomina, Daria Fomina

“…The gene encodes a ubiquitous non-receptor T-cell protein tyrosine phosphatase that exerts a negative feedback on the JAK–STAT pathway. …”
Get full text

An integrative analysis of ASCL1 in breast cancer and inhibition of ASCL1 increases paclitaxel sensitivity by activating ferroptosis via the CREB1/GPX4 axis by Xiaolu Yang, Xiaolu Yang, Yilun Li, Yilun Li, Yaqi Peng, Yuan Chang, Binglu He, Binglu He, Tianqi Zhang, Tianqi Zhang, Shiyu Zhang, Cuizhi Geng, Yunjiang Liu, Xiaolong Li, Jun Hao, Li Ma

“…Notably, inhibition of ASCL1 increased BC cell sensitivity to paclitaxel both in vitro and in vivo. …”
Get full text

Therapeutic benefit of the dual ALK/FAK inhibitor ESK440 in ALK-driven neuroblastoma by Seema Chugh, Jean C. Tien, Jennifer Hon, Carson Kenum, Rahul Mannan, Yunhui Cheng, Chi Chiang Li, Zainab I. Taher, Andrew D. Delekta, Pushpinder Singh Bawa, Ingrid J. Apel, Stephanie J. Miner, Xuhong Cao, Rohit Mehra, Saravana M. Dhanasekaran, Yuanyuan Qiao, Rajen Mody, Arul M. Chinnaiyan

“…ESK440 potently inhibited proliferation of NB cell lines, with increased sensitivity in cell lines harboring ALK aberrations. …”
Get full text

Insights into the mechanisms of serplulimab: a distinctive anti-PD-1 monoclonal antibody, in combination with a TIGIT or LAG3 inhibitor in preclinical tumor immunotherapy studies by Yizhou Zhang, Ruicheng Wei, Ge Song, Xinyi Yang, Mengli Zhang, Wei Liu, Aiying Xiong, Xuehan Zhang, Qianhao Li, Wan-Jen Yang, Chencheng Han, Rui Liu, Chen Hu, Qingyu Wang, Jun Zhu, Yongqiang Shan

“…Mechanistically, the serplulimab combination effectively reduces tumor microenvironment Treg cell populations, augments effector and memory T cell populations, and more potently modulates genes associated with diverse facets of the immune system, surpassing the effects of the pembrolizumab combination. …”
Get full text

Clinical impact of [18F]FDG-PET/CT in ARI0002h treatment, a CAR-T against BCMA for relapsed/refractory multiple myeloma by Inés Zugasti, Marta Tormo-Ratera, Aina Oliver-Caldés, Juan Carlos Soler-Perromat, Verónica González-Calle, David F. Moreno, Valentín Cabañas, Nieves López-Muñoz, Álvaro Bartolomé-Solanas, Marta Español-Rego, Juan Luis Reguera-Ortega, Laura Rosiñol, Lucía López-Corral, Natalia Tovar, Luis Gerardo Rodríguez-Lobato, Rosa Maria Alvarez Perez, Sara Varea, Eulàlia Olesti, Adolfo Gomez-Grande, Laura Frutos, Pilar Tamayo, Manel Juan, José M. Moraleda, Álvaro Urbano-Ispizua, E. Azucena González-Navarro, Joaquín Martínez-López, Maria-Victoria Mateos, Xavier Tomás, Xavier Setoain, Carlos Fernández de Larrea

“…This study included 63 patients with relapsed/refractory MM treated either in the CARTBCMA-HCB-01 clinical trial (ARI0002h; academic B-cell maturation antigen [BCMA]–targeted CAR T-cell therapy) or in compassionate use. …”
Get full text

Blue rings in trees and shrubs as indicators of early and late summer cooling events at the northern treeline by Agata Buchwal, Agata Buchwal, Pawel Matulewski, Ylva Sjöberg, Alma Piermattei, Alma Piermattei, Alan Crivellaro, Alan Crivellaro, Angela Balzano, Maks Merela, Luka Krže, Katarina Čufar, Alexander V. Kirdyanov, Alexander V. Kirdyanov, Tatiana Bebchuk, Tito Arosio, Ulf Büntgen, Ulf Büntgen, Ulf Büntgen

“…Also, after 1902 BR, Pinus trees exclusively showed no recovery in the mean cell wall thickness in the following year. Our study provides the first evidence for different impacts of early versus late growing season cooling on cell wall lignification in trees and shrubs at the northern treeline. …”
Get full text

Beneficial Effects of Resveratrol-Mediated Inhibition of the mTOR Pathway in Spinal Cord Injury by Jingying Zhou, Xue Huo, Benson O. A. Botchway, Luyao Xu, Xiaofang Meng, Songou Zhang, Xuehong Liu

“…Resveratrol has the potential of regulating cell growth, proliferation, metabolism, and angiogenesis through the mTOR signaling pathway. …”
Get full text

Advances in the understanding and therapeutic manipulation of cancer immune responsiveness: a Society for Immunotherapy of Cancer (SITC) review by Francesco M Marincola, Alessandra Cesano, Yana G Najjar, Davide Bedognetti, Marco Ruella, Sarah Warren, Christine Spencer, Elad Ziv, Tomas Kirchhoff, Jennifer McQuade, Tullia C Bruno, Jakob Nikolas Kather, Allison Betof Warner, Christian Hammer, Alberto Carturan, Ryan Augustin, Rhine Shen, Winson S Ho, Rongze O Lu, Luigi Barrea, Violena Pietrobon, Laura Soldati

“…Cancer immunotherapy—including immune checkpoint inhibition (ICI) and adoptive cell therapy (ACT)—has become a standard, potentially curative treatment for a subset of advanced solid and liquid tumors. …”
Get full text

Manifestation of plasmablastic lymphoma in the oral cavity: Report of two cases and literature review by Letícia da Silva Soares Gomes, Caroline Alfaia Silva, André Luiz Carvalho Barreiros, Patrick Rocha Osborne, Jeconias Câmara, Tiago Novaes Pinheiro, Christina Shiang, José Augusto Andrade Godoy Bezerra, Naíza Menezes Medeiros Abrahim, Luciana Botinelly Mendonça Fujimoto

“…Plasmablastic lymphoma (PBL) is a rare and aggressive non- Hodgkin 's B-cell lymphoma initially reported in patients with the HIV virus with a predilection for the oral cavity. …”
Get full text