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23081
Role of B7‐H3 in predicting response to neoadjuvant chemotherapy in muscle‐invasive bladder cancer
Published 2024-11-01“…B7‐H3 (CD276), an immune checkpoint overexpressed in various cancers, including urothelial‐cell carcinoma (UCC), has been associated with chemoresistance and poor oncologic outcomes. …”
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23082
Phytochemicals for mitigating the COVID-19 crisis: evidence from pre-clinical and clinical studies
Published 2023-10-01“…These findings suggest that multiple phytochemicals can interfere with virus entry and replication inside the host cell. Many of them can protect from cytokine storm by acting on intracellular signalling pathways in addition to inhibiting virus multiplication. …”
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23083
Analysis of oral cancer carcinogens in repeatedly heated cooking oils
Published 2025-01-01“…The incidence of oral cancer in recent years has been on the rise; ninety percent of the cancers present in the oral cavity are squamous cell carcinoma with multiple major contributing lifestyle factors such well as the presence of the human papilloma virus. …”
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23084
Reduction effect of oral pravastatin on the acute phase response to intravenous zoledronic acid: protocol for a real-world prospective, placebo-controlled trial
Published 2022-07-01“…This process can decrease the accumulation of isopentenyl pyrophosphate to prevent γδT-cell activation and inflammatory factor production, blocking APR occurrence. …”
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23085
The comprehensive assessment of epigenetics changes during skin development
Published 2025-01-01“…However, the minimal erythema dose of UV exposure altered multiple epigenetic effectors regulating extracellular matrix organization, cell-matrix adhesion, innate immune response, mitochondrial function and mRNA processing. …”
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23086
Water-Soluble Vitamins: Hypo- and Hypervitaminosis in Pediatric Population
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23087
Magnitude, Severity, and Associated Factors of Anemia among Under-Five Children Attending Hawassa University Teaching and Referral Hospital, Hawassa, Southern Ethiopia, 2016
Published 2020-01-01“…Venous blood samples were collected and analyzed for hemoglobin determination using a Cell-Dyn 1800 automated analyzer. Stool samples were collected and processed using direct wet mount and formol-ether concentration method to detect intestinal parasites. …”
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23088
Comprehensive analysis of histophysiology, transcriptomics and metabolomics in goslings exposed to gossypol acetate: unraveling hepatotoxic mechanisms
Published 2025-01-01“…Overall, GA-induced hepatotoxicity involves impaired energy production, disrupted lipid metabolism, and abnormal liver focal adhesion, leading to liver cell dysfunction. These findings highlight the vulnerability of mitochondria and critical metabolic pathways, providing insights into the molecular mechanisms of GA toxicity and guiding future studies on mitigating GA-induced liver damage in goslings.…”
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23089
Transcriptomics-based analysis of neurotoxic and reproductive effects in turbot (Scophthalmus maximus) after exposure to tris (2-chloroethyl) phosphate (TCEP)
Published 2025-01-01“…Among these genes, those encoding the components of the electron transport chain presented an initial increase in expression followed by a decrease, indicating that TCEP stress might affect mitochondrial function and lead to cell damage. This finding was also supported by the upregulation of apoptosis-related gene expression. …”
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23090
Phytochemical and toxicological evaluation of aqueous leaf extract of Premna integrifolia L. in male balb/c mice
Published 2025-02-01“…The parameters studied included total reactive oxygen species (ROS) production, apoptosis, cell viability percentage, and cellular morphology. …”
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23091
Clinical Effect and Rotational Stability of TICL in the Treatment of Myopic Astigmatism
Published 2020-01-01“…The uncorrected and best-corrected visual acuity (UCVA and BCVA), astigmatism and spherical equivalent, intraocular pressure, vault, endothelial cell morphometry, and rotation of the TICL axis were assessed at l day, 1 week, 1 month, 3 months, 6 months, and 12 months postoperatively. …”
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23092
Is Lung Disease a Risk Factor for Sudden Cardiac Death? A Comparative Case–Control Histopathological Study
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23093
Primary and tertiary management of ocular surface lesions in HIV-infected patients in Ehlanzeni, Mpumalanga Province
Published 2024-06-01“…Fifty percent had carcinoma-in situ and squamous cell carcinoma of the conjunctiva. Thirty-one (50%) of the patients were lost to follow-up. …”
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23094
A human acellular dermal matrix coated with zinc oxide nanoparticles accelerates tendon repair in patients with hand flexor tendon injuries in zone 5 of the hand
Published 2024-09-01“…Methods: Morphological, mechanical, cell viability, and antibacterial tests were performed to evaluate the physical and biological properties of the fabricated ADM/ZnO-NPs graft. …”
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23095
Valorisation et sauvegarde de l’identité socio-culturelle fang de Guinée Équatoriale et du Gabon dans les romans Herencia de Binendee et le pacte d’Afia
Published 2025-01-01“…Le roman du Gabonais, Maurice Okoumba-Nkoghe, Le pacte d’Afia (2009/2022) jette les bases du féminisme africain tandis que Herencia de Bindendee (2016) de la Guinéo-équatorienne, Trifonia Melibea Obono interroge les mentalités africaines patriarcales en général et celles guinéo-équatoriennes en particulier. À partir d’une approche féministe et sémiologique, la présente étude interroge les mécanismes romanesques des auteurs par lesquels se déploie le fang dans les romans étudiés comme en témoigne, leur titrologie. …”
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23096
Liraglutide Regulates the Kidney and Liver in Diabetic Nephropathy Rats through the miR-34a/SIRT1 Pathway
Published 2021-01-01“…Additionally, the liraglutide-treated DN rats had a clear hepatic structure, a lower degree of steatosis, and mild inflammatory cell infiltration. Conclusion. Liraglutide, through its effect on the miR-34a/SIRT1 pathway, may have a protective role in the kidney and liver of DN rats.…”
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23097
Construction of prokaryotic system for expression of porcine circovirus type 2 ORF-2 gene fragment
Published 2024-03-01“…It was shown that the positivity coefficient of producer strain cell lysates averaged to 4.34 (p < 0.005). The recombinant rCap protein is suitable for serological diagnosis and is also of interest as a vaccine component, which is the goal of our further studies.…”
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23098
Investigation of Coolant Local Hydrodynamics in the Mixed Core of the VVER Reactor
Published 2020-03-01“…The results of the study of the coolant cross flow between fuel assemblies interaction, i.e. between the adjacent TVSA-T and TVSA-T mod.2 fuel assemblies were adopted for practical use in the JSC of “Afrikantov OKB Mechanical Engineering” for assessing the heat engineering reliability of VVER reactor cores; also, they were included in the database for verification of computational hydrodynamics programs (CFD codes) and for detailed cell-based calculation of the reactor core.…”
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23099
Perianal Paget’s Disease: The 17-Year-Experience of a Single Institution in Taiwan
Published 2019-01-01“…Other synchronous or metachronous malignancies included cholangiocarcinoma, urothelial carcinoma, anorectal small-cell carcinoma, and unknown hepatic malignancy. One primary PPD patient died from the metastases of invasive Paget’s disease while 3 secondary PPD patients died from the metastases of CRCs during follow-up. …”
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23100