TockyPrep: data preprocessing methods for flow cytometric fluorescent timer analysis by Masahiro Ono

“…Abstract Background: Fluorescent Timer proteins, which display time-dependent changes in their emission spectra, are invaluable for analyzing the temporal dynamics of cellular events at the single-cell level. We previously developed the Timer-of-cell-kinetics-and-activity (Tocky) tools, utilizing a specific Timer protein, Fast-FT, to monitor temporal changes in cellular activities. …”
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Phenotyping of Leukocytes and Leukocyte-Derived Extracellular Vesicles by Lotte Hatting Pugholm, Rikke Bæk, Evo Kristina Lindersson Søndergaard, Anne Louise Schacht Revenfeld, Malene Møller Jørgensen, Kim Varming

“…The majority of the lineage-specific markers used for identification of the parent cell types could not be detected on EVs released from monocultures of the associated cell types. …”
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Electric field stimulation directs target-specific axon regeneration and partial restoration of vision after optic nerve crush injury. by Timothy Kim, Ege Iseri, Micalla G Peng, Sasha Medvidovic, Timothy Silliman, Pooyan Pahlavan, Gengle Niu, Connie Huang, Anahit Simonyan, Javad Pahnahad, Petcy Yao, Phillip Lam, Vahini Garimella, Mahnaz Shahidi, Michael S Bienkowski, Darrin J Lee, Biju Thomas, Gianluca Lazzi, Kimberly K Gokoffski

“…Our work suggests that exogenous electric field application can override cell-intrinsic and cell-extrinsic barriers to axon regeneration, and that electrical stimulation performed with specific ACB waveforms may be an effective strategy for directing anatomical and functional restoration after CNS injury.…”
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Differences between Infected and Noninfected Patients with Acute Alcoholic Hepatitis by GY Minuk, A Cohen, V Thompson

“…These results suggest that the extent and timing of peak abnormalities in body temperature, white blood cell count and serum bilirubin level may be of value in distinguishing patients with alcoholic hepatitis with bacterial infections from patients with alcoholic hepatitis alone.…”
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Neurotoxic Dorsal CA1 Lesions versus 4 VO Ischaemic Lesions: Behavioural Comparisons by J. A. Nunn, J. A. Gray, H. Hodges

“…Anterograde amnesia, a common consequence of transient cerebral ischaemia, has been attributed to cell loss in the hippocampal CA1 subfield. However, variable, widespread damage outside hippocampal CA1 can also occur following ischaemia. …”
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IL-32: A Novel Pluripotent Inflammatory Interleukin, towards Gastric Inflammation, Gastric Cancer, and Chronic Rhino Sinusitis by Muhammad Babar Khawar, Muddasir Hassan Abbasi, Nadeem Sheikh

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Phospholipase A2 Mediates Apolipoprotein-Independent Uptake of Chylomicron Remnant-Like Particles by Human Macrophages by Mariarosaria Napolitano, Howard S. Kruth, Elena Bravo

“…The role of lipases, including lipoprotein lipase, cholesteryl ester hydrolase, and secretory (sPLA2) and cytosolic phospholipase A2, was studied using [3H]TG-labelled CRLPw/o. Total cell radioactivity after incubation with [3H]TG CRLPw/o was reduced by 15–30% by inhibitors of lipoprotein lipase and cholesteryl ester hydrolase and by about 45% by inhibitors of sPLA2 and cytosolic PLA2 . …”
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Development of a half-meter scale Traveling-Wave (TW) SRF cavity by Furuta Fumio, Kazakov Sergey, Khabiboulline Timergali, McGee Kellen, Ng Trista, Yakovlev Vyacheslav

“…It consists of a 7-cell structure and a power feedback waveguide (WG) loop with new RF configurations to control TW resonance. …”
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Neutrophil-to-lymphocyte ratio and short-term mortality in patients having anti-MDA5-positive dermatomyositis with interstitial lung disease: a retrospective study by Hongxia Xin, Ping He, Bin Xi, Zhaojun Wang, Han Wang, Faxuan Wang, Zhanbing Ma, Jing Xue, Yuanyuan Jia, Hourong Cai, Bi Chen, Juan Chen

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Multiomic characterization, immunological and prognostic potential of SMAD3 in pan-cancer and validation in LIHC by Tao Zhou, Dan Dan Zhang, Jiejing jin, Jinyang Xie, Jianhua Yu, Chao Zhu, Rong Wan

“…Single-cell sequencing results elucidated the pan-cancer single-cell expression landscape of SMAD3. …”
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Cyclin E1/CDK2 activation defines a key vulnerability to WEE1 kinase inhibition in gynecological cancers by Daehwan Kim, Heekyung Chung, Wen Liu, Kangjin Jeong, Tugba Y. Ozmen, Furkan Ozmen, Matthew J. Rames, Sangyub Kim, Xiao Guo, Nathan Jameson, Petrus R. de Jong, Steven Yea, Laurie Harford, Jiali Li, Cara A. Mathews, Deborah B. Doroshow, Vincent J. Charles, Doris Kim, Kimberlee Fischer, Ahmed A. Samatar, Adrian Jubb, Kevin D. Bunker, Kimberly Blackwell, Fiona Simpkins, Funda Meric-Bernstam, Gordon B. Mills, Olivier Harismendy, Jianhui Ma, Mark R. Lackner

“…Abstract Upregulation of Cyclin E1 and subsequent activation of CDK2 accelerates cell cycle progression from G1 to S phase and is a common oncogenic driver in gynecological malignancies. …”
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Identification of Associations with Dermatologic Diseases through a Focused GWAS of the UK Biobank by Jason C. Klein, Ruchika Mahapatra, Gary C. Hon, Richard C. Wang

“…We perform a focused analysis of the UK Biobank for 13 dermatologic conditions, including malignant melanoma, melanoma in situ, squamous cell carcinoma, basal cell carcinoma, actinic keratosis, seborrheic keratosis, psoriasis, lichen planus, systemic lupus erythematosus, hyperhidrosis, pilonidal cyst, sebaceous cyst, and lipoma. …”
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Hybrid Technique of Lamellar Keratoplasty (DMEK-S) by Pavel Studeny, Deli Sivekova, Katerina Liehneova, Magdalena Vokrojova, Pavel Kuchynka

“…The outcome measures studied were visual acuity and endothelial cell density. Results: The rate of endothelial cell loss caused by surgery was 43.8%. …”
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Dominant spoilage bacteria in crayfish alleviate ultrasonic stress through mechanosensitive channels but could not prevent the process of membrane destruction by Zechuan Dai, Lingyun Meng, Sai Wang, Jiao Li, Xiangzhao Mao

“…The results showed compromised cell membrane, decreased membrane fluidity, hyperpolarized membrane potential, and disrupted succinate-coenzyme Q reductase. …”
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The Role of Connexin-43 in the Inflammatory Process: A New Potential Therapy to Influence Keratitis by Chu-Yang Xu, Wen-Song Zhang, Hong Zhang, Yan Cao, Hong-Yan Zhou

“…Some ions and small molecules are exchanged from cell to cell or cell to extracellular space to affect the process of inflammation via GJ. …”
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Synergistic effects of platelet-rich fibrin and photobiomodulation on bone regeneration in MC3T3-E1 Preosteoblasts by Ling-Hung Chou, Tzu-Sen Yang, Pei-Chun Wong, Ying-Chun Chen

“…Background: Platelet-rich fibrin (PRF) and Photobiomodulation (PBM) are established methods for promoting bone healing. PRF enhances cell proliferation and migration due to its rich concentration of growth factors, while PBM stimulates tissue repair through mitochondrial activation. …”
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Phytochemical and Antibacterial Investigations of the Extracts and Fractions from the Stem Bark of Hymenaea stigonocarpa Mart. ex Hayne and Effect on Ultrastructure of Staphylococc... by Gustavo Santiago Dimech, Luiz Alberto Lira Soares, Magda Assunção Ferreira, Anne Gabrielle Vasconcelos de Oliveira, Maria da Conceição Carvalho, Eulália Azevedo Ximenes

“…Presence of the thick cell wall, undulating outer layer, abnormal septa, and leakage of the cytoplasmic contents and absence of cell wall and cell lyses were the main alterations observed on Staphylococcus aureus ATCC 33591 after treatment with the Hymenaea stigonocarpa hydroalcoholic extract. …”
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Proteomic Technology “Lens” for Epithelial-Mesenchymal Transition Process Identification in Oncology by Monica Neagu, Carolina Constantin, Marinela Bostan, Constantin Caruntu, Simona Rebeca Ignat, Sorina Dinescu, Marieta Costache

“…Proteomics has brought besides standard EMT markers (e.g., cell-cell adhesion proteins and transcription factors) other future potential markers for improving diagnosis, monitoring evolution, and developing new therapy targets. …”
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Inhibition of AKT enhances chemotherapy efficacy and synergistically interacts with targeting of the Inhibitor of apoptosis proteins in oesophageal adenocarcinoma by Leanne Stevenson, Lauren Cairns, Xiaodun Li, Sriganesh Jammula, Harriet Taylor, Rosalie Douglas, Niamh McCabe, Gerald Gavory, Xavier Jacq, Rebecca C. Fitzgerald, Richard D. Kennedy, Timothy Harrison, Richard C. Turkington

“…Combined AKT and IAP inhibition synergistically enhanced OAC cell death and successfully re-sensitized ALM301 and chemotherapy resistant cell lines. …”
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Enhanced Performance of New Scaling-Free CORDIC for Memory-Based Fast Fourier Transform Architecture by C. Paramasivam, Sandeep Singh Chauhan, Veerpratap Meena, A. Sreejagathi, B. A. V. N. Hasini, K. L. K. Kishore, T. V. N. G. Vamsikrishna, M. Durga Ananta Sai, Abdessamad Didi

“…Further, a memory-based FFT architecture is designed using a new CORDIC cell. In the FFT architecture, the CORDIC cell performs all the multiplication of twiddle factor. …”
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