Exploring <i>RNF213</i> in Ischemic Stroke and Moyamoya Disease: From Cellular Models to Clinical Insights by Benjamin Y. Q. Tan, Charlene H. P. Kok, Megan B. J. Ng, Shaun Loong, Eric Jou, Leonard L. L. Yeo, Weiping Han, Christopher D. Anderson, Chiea Chuen Khor, Poh San Lai

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Anti-Inflammatory Effect Fraction of Bletilla striata and Its Protective Effect on LPS-Induced Acute Lung Injury by Chunchun Zhang, Dandan Ning, Jieli Pan, Cheng Chen, Chengxian Gao, Zhishan Ding, Fusheng Jiang, Meiya Li

“…Meanwhile, the main anti-inflammation-contributing ingredients and possible molecular mechanism of anti-inflammatory activity in EFBS were verified by component-knockout method combined with LPS-induced RAW264.7 cell model. The EFBS mainly consisted of coelonin (15.88%), batatasin III (32.49%), 3′-O-methylbatatasin III (6.96%), and 3-hydroxy-5-methoxy bibenzyl (2.51%). …”
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Ferric Carboxymaltose in the Management of Iron Deficiency Anemia in Pregnancy: A Subgroup Analysis of a Multicenter Real-World Study Involving 1191 Pregnant Women by Prakash Trivedi, S. Chitra, Suma Natarajan, Vandana Amin, Shilpi Sud, Priti Vyas, Meenakshi Singla, Ajinkya Rodge, Onkar C. Swami

“…Similarly, there was a significant increase in red blood cell count, hematocrit, mean corpuscular volume, and mean corpuscular hemoglobin (P<0.001 for all). …”
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Parent-of-origin effects on nuclear chromatin organization and behavior in a Drosophila model for Williams–Beuren Syndrome by A. V. Medvedeva, E. V. Tokmatcheva, A. N. Kaminskaya, S. A. Vasileva, E. A. Nikitina, A. V. Zhuravlev, G. A. Zakharov, O. G. Zatsepina, E. V. Savvateeva-Popova

“…Prognosis of neuropsychiatric disorders in progeny requires consideration of individual (1) parent-of-origin effects (POEs) relying on (2) the nerve cell nuclear 3D chromatin architecture and (3) impact of parent-specific miRNAs. …”
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The transcriptional response to yellow and wilt disease, caused by race 6 of Fusarium oxysporum f. sp. Ciceris in two contrasting chickpea cultivars by Aliakbar Faramarzpour, Sara Dezhsetan, Hamid Hassaneian Khoshro, Raheleh Mirdar Mansuri, Hamid Reza Pouralibaba, Zahra-Sadat Shobbar

“…., CaMYBs, CaGLK, CaERFs, CaZAT11-like, and CaNAC6) and cell wall integrity (e.g., CaPGI2-like, CaEXLs, CaCSLD and CaCYP73A100-like). …”
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Factor V H1299r (Hr2) Heterozygosity: A Risk Factor For Recurrent Implantation Failure Particularly In Non-Carriers For Factor V Leiden Mutation-A Case-Control Study by A. Seval Ozgu-Erdinc, Pınar Gulsen Coban, Nafiye Yilmaz, Zuhal Candemir, Saynur Yilmaz, Salim Erkaya

“…Study Design: A total of 279 women were recruited in this case-control study. 229 women with a history of recurrent implantation failure and 50 fertile control with no history of pregnancy losses were screened for eight specific gene mutations, regarding factor V G1691A gene (FV Leiden), FV HR2, factor II prothrombin G20210A, factor XIII V34L, PAI-1 4G/5G, MTHFR C677T, MTHFR A1298C and A3 haplotype of the endothelial cell protein C receptor gene. Results: Recurrent implantation failure group displayed a significantly higher prevalence of FV HR2 heterozygosity than fertile controls while the frequency of FV Leiden mutation was comparable between groups (p=0.011; p=0.619). …”
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Antiallodynic Effects of Cannabinoid Receptor 2 (CB2R) Agonists on Retrovirus Infection-Induced Neuropathic Pain by Wen S. Sheng, Priyanka Chauhan, Shuxian Hu, Sujata Prasad, James R. Lokensgard

“…Infection-induced macrophage activation and T-cell infiltration into the DRG and LSC were observed at 12 wk p.i., but this neuroinflammation was not affected by treatment with any CB2R agonist. …”
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Benefits of Virgin Coconut Oil in Diet to Colossoma macropomum (Cuvier, 1818) by Márcia Valéria Silva do Couto, Natalino da Costa Sousa, Higo Andrade Abe, Joel Artur Rodrigues Dias, Carlos Alberto Martins Cordeiro, Peterson Emmanuel Guimarães Paixão, Thays Brito Reis Santos, Fernanda dos Santos Cunha, Juliana Oliveira Meneses, Ricardo Marques Nogueira Filho, Carol Nunes Costa Bomfim, Cláucia Aparecida Honorato, Bruno Trindade Cardoso, Rodrigo Yudi Fujimoto

“…At end of experiment, the fish were subjected to bacterial challenge and blood analysis (glucose, lactate, plasmatic protein, and red cell blood). Fish fed 0%, 100% of VCO and lauric acid presented lower growth than fish fed 50% of virgin coconut oil (VCO) which presents the highest biomass (929.8±80.6a) and weight gain (15.4±4.3a) (p<0.05). …”
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Sex differences in the time trends of sepsis biomarkers following polytrauma by Cédric Niggli, Philipp Vetter, Jan Hambrecht, Hans-Christoph Pape, Ladislav Mica

“…This study examined the time-dependent behavior of C-reactive protein (CRP), procalcitonin (PCT), and white blood cell count (WBC) in male and female polytrauma patients to evaluate their predictive value for sepsis. …”
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Comparative Analysis of the Safety and Functional Outcomes of Anterior versus Retropupillary Iris-Claw IOL Fixation by Paolo Mora, Giacomo Calzetti, Stefania Favilla, Matteo Forlini, Salvatore Tedesco, Purva Date, Viola Tagliavini, Arturo Carta, Rino Frisina, Emilio Pedrotti, Stefano Gandolfi

“…The following parameters were compared between the groups: best-corrected distance visual acuity (BCDVA), spherical and cylindrical refractive error, endothelial cell density (ECD), central macular thickness (CMT), and percentage and type of postoperative complications. …”
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Knowledge and attitude among Egyptian medical students regarding the role of human papillomavirus vaccine in prevention of oropharyngeal cancer: a questionnaire-based observational... by Mohammed. N. Abdelaziz, Abdullah Hefnawy, Hajer Azzam, Omar Reisha, Omar Hamdy

“…Abstract Squamous cell carcinomas in several anatomical sites are caused by human papillomaviruses (HPV), and oncogenic double-stranded DNA viruses. …”
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Impaired fracture healing is associated with callus chondro-osseous junction abnormalities in periostin-null and osteopontin-null mice by Marc Teitelbaum, Marc Teitelbaum, Maya D. Culbertson, Charlene Wetterstrand, J. Patrick O’Connor, J. Patrick O’Connor

“…Null mutation of either the periostin (Postn) gene or the osteopontin (Spp1) gene can impair bone fracture healing. However, the cell and molecular pathways affected by loss of POSTN or SPP1 which lead to impaired fracture healing are not well understood. …”
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Synthesis and antitumor activity of some novel thiophene, pyrimidine, coumarin, pyrazole and pyridine derivatives by Albratty Mohammed, El-Sharkawy Karam Ahmed, Alam Shamsher

“…Some of these compounds showed promising inhibitory effects on three different cell lines. However, fused pyrimidine acetonitrile derivatives 6a and 6b exerted the highest inhibitory effect, comparable to that of doxorubicin.…”
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First Report on Microbial-Derived Polydeoxyribonucleotide: A Sustainable and Enhanced Alternative to Salmon-Based Polydeoxyribonucleotide by Doobyeong Chae, Sae-Woong Oh, Yoon-Seo Choi, Dae-Jung Kang, Chun-Woong Park, Jongsung Lee, Won-Sang Seo

“…In wound-healing assays, L-PDRN demonstrated superior efficacy in promoting cell migration and wound closure, even under inflammatory conditions induced by tumor necrosis factor (TNF-α). …”
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Curcumin nanoparticles alleviate brain mitochondrial dysfunction and cellular senescence in γ-irradiated rats by Omnia A. Moselhy, Nahed Abdel-Aziz, Azza El-bahkery, Said S. Moselhy, Ehab A. Ibrahim

“…Abstract Despite the diverse applications of γ radiation in radiotherapy, industrial processes, and sterilization, it causes hazardous effects on living organisms, such as cellular senescence, persistent cell cycle arrest, and mitochondrial dysfunction. …”
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Enhancing postharvest quality of bananas: comparative study on the use ZnO and Ag2O nanoparticles and ZnO/Ag2O composites by Noluthando Noxolo Aruwajoye, Isaac Adeyemi Sanusi, Gabriel Sanjo Aruwajoye, Asanda Mditshwa, Samson Zeray Tesfay

“…Remarkably, the Ag2O + ZnO composite formulation showed the most significant positive effects on total acidity, pH, and stomatal cell integrity toward improving banana quality. This study highlights the potential of ZnO/Ag2O composites as effective postharvest treatments to enhance banana quality and extend shelf life, providing a promising approach to reduce postharvest losses and ensure fruit quality during storage and transportation.…”
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HACE1 protects against myocardial ischemia–reperfusion injury via inhibition of mitochondrial fission in mice by Bang-Xia Liu, Juan Zheng, Zhan-Wei Tang, Lei Gao, Meng Wang, Ying Sun, Chen Chen, Heng-Chen Yao

“…Conclusion Collectively, our data show that myocardial I/RI is associated with HACE1 downregulation and Drp1 activation, causing cardiomyocytes to undergo cell death. Therefore, HACE1 could be a promising therapeutic target for the treatment of myocardial I/RI.…”
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THE DEVELOPMENT OF SCIENCE AND THE FATE OF A SCIENTIST (FOLLOWING GENETICS) by Jonas Rubikas

“…The beginners and the levels are as follows: 1) G. Mendel, 1865, "The Cell–The Feature"; 2) T. H. Morgan, 1911, "The Chromosome–The Feature"; 3) O. …”
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Prognostic factors for head and neck cancer of unknown primary including the impact of human papilloma virus infection by Lars Axelsson, Jan Nyman, Hedda Haugen-Cange, Mogens Bove, Leif Johansson, Shahin De Lara, Anikó Kovács, Eva Hammerlid

“…The medical records were reviewed, and only patients with squamous cell carcinoma or undifferentiated carcinoma treated with curative intent were included. …”
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Heterogeneity in Fluorescence-Stained Sperm Membrane Patterns and Their Dynamic Changes Towards Fertilization in Mice by Momoka Hirai, Satoshi Kishigami

“…Methods: Sperm were collected from the cauda epididymis or testis of Institute of Cancer Research (ICR) male mice and stained with MemBright dye (commercial name: MemGlow™-560, MG-560), a fluorogenic live-cell membrane probe. Staining was performed either before, during, or after incubation for capacitation. …”
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