The Increased Circulating Plasma Levels of Vascular Endothelial Growth Factor in Patients with Type 1 Diabetes Do Not Correlate to Metabolic Control by Kailash Singh, Stellan Sandler, Daniel Espes

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Regulation of Metabolic Disease-Associated Inflammation by Nutrient Sensors by Alex S. Yamashita, Thiago Belchior, Fábio S. Lira, Nicolette C. Bishop, Barbara Wessner, José C. Rosa, William T. Festuccia

“…Visceral obesity is frequently associated with the development of type 2 diabetes (T2D), a highly prevalent chronic disease that features insulin resistance and pancreatic β-cell dysfunction as important hallmarks. Recent evidence indicates that the chronic, low-grade inflammation commonly associated with visceral obesity plays a major role connecting the excessive visceral fat deposition with the development of insulin resistance and pancreatic β-cell dysfunction. …”
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A Review of Routine Laboratory Biomarkers for the Detection of Severe COVID-19 Disease by Keynaz Keykavousi, Fahimeh Nourbakhsh, Nooshin Abdollahpour, Farzaneh Fazeli, Alireza Sedaghat, Vahid Soheili, Amirhossein Sahebkar

“…Once the coronavirus enters the cell, it triggers additional events via different signaling pathways. …”
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Intestinal Adenocarcinoma Arising from a Mature Cystic Teratoma by King Man Wan, Forough Foroughi, Rajni Bansal, Martin K. Oehler

“…Mature cystic teratomas are the most common ovarian germ cell tumour and account for 10–20% of all ovarian neoplasms. …”
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Performance Evaluation of Energy Efficiency in Dense Heterogeneous Wireless Network by Hengzhi Zhang, Zhongyuan Zhao, Fudong Yang, Yong Li

“…In dense heterogeneous wireless network, the large-scale small cell deployment can substantially increase not only the complexity of the interference environment but also the network energy consumption. …”
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CAC scheme with imperfect power control in broadband CDMA networks by GAO Yong-hui1, ZHANG Dan-dan2

“…Putting forward the CAC schemes with imperfect power control for multimedia traffic would be great signifi-cant.The system capacity with imperfect power control and the other-cell to intra-cell interference factor was analyzed.And then considering the voice/video/data multimedia traffic scenario,a novel QoS（quality of service） based on CAC scheme was proposed.The simulation results show that the system capacity is heavily affected by the imperfect power control,and the proposed scheme can guarantee the QoS for different traffic efficiently,and improves the resource utility significantly.…”
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Impaired inflammatory resolution with severe SARS-CoV-2 infection in leptin knock out obese hamster by Ren-Di Jiang, Yun-Zhe Luo, Hao-Feng Lin, Xiao-Shuang Zheng, Wen-Tao Zeng, Mei-Qin Liu, Hao-Hao Deng, Qi Wang, Ya-Na Lai, Ying Chen, Zi-Shuo Guo, Ya Zeng, Qian-Chun Gong, Chen Qiu, Mei Dong, Xi Wang, Zi-Yi Wang, Li-Na Ji, Pan-Pan Hou, Qian Li, Xu-Rui Shen, Bei Li, Yun Gao, Ai-Hua Zhang, Ting-Ting Jiang, Ai-Min Shi, Peng Zhou, Xin-Hua Lin, Zi-Qing Deng, Jian-Min Li, Zheng-Li Shi

“…This model exhibits robust viral replication, severe lung lesions, pronounced clinical symptoms, and fatal infection, mirroring severe COVID-19 in patients with obesity. Using single-cell transcriptomics on lung tissues pre- and post-infection, we found that monocyte-derived alveolar macrophages (MD-AM) play a key role in lung hyper-inflammation, including two unique MD-AM cell fate branches specific to Leptin−/− hamsters. …”
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A tribute to François Gros, a founding father of molecular biology: Foreword by Buckingham, Margaret, Yaniv, Moshe

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Uplink capacity analysis of two-hop-relay CDMA cellular systems by LU Wei-feng1, WU Meng2

“…Based on the two-hop-relay CDMA cellular systems,two kinds of out-of-band relaying methods were pro-posed to improve the conventional CDMA cellular systems.Then by analyzing the interference power of the non-relaying CDMA cellular systems,the overall interference power to own and neighbor cell could be obtained with using these two relaying methods.Finally,based on a symmetrical cell model,the uplink capacity of two-hop-relay CDMA cellular sys-tems was analyzed by mathematical calculating,and the impact of these two relaying methods on system’s performance was discussed.…”
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Transferrin Disassociates TCR from CD3 Signaling Apparatus to Promote Metastasis by Ruomei Cheng, Xiaopeng Tang, Qiyu Zhao, Yuming Wang, Wenlin Chen, Gan Wang, Chenxi Wang, James Mwangi, Qiumin Lu, Dawit Adisu Tadese, Xudong Zhao, Caiwen Ou, Ren Lai

“…Immune recognition and activation by the peptide-laden major histocompatibility complex–T cell receptor (TCR)–CD3 complex is essential for anti-tumor immunity. …”
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Molecular dynamics model of mechanophore sensors for biological force measurement by Sumit Mittal, Rongsheng E. Wang, Robert Ros, Alison E. Ondrus, Abhishek Singharoy

“…Cellular forces regulate an untold spectrum of living processes, such as cell migration, gene expression, and ion conduction. …”
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Hydrogen Supplementation of Preservation Solution Improves Viability of Osteochondral Grafts by Takuya Yamada, Kentaro Uchida, Kenji Onuma, Jun Kuzuno, Masanobu Ujihira, Gen Inoue, Bunpei Sato, Ryosuke Kurokawa, Rina Sakai, Masashi Takaso

“…Typically, OCTs collected during the disease-screening period are preserved at 4°C; however, the gradual reduction in cell viability during cold preservation adversely affects transplantation outcomes. …”
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Low dimensionality of phenotypic space as an emergent property of coordinated teams in biological regulatory networks by Kishore Hari, Pradyumna Harlapur, Aashna Saxena, Kushal Haldar, Aishwarya Girish, Tanisha Malpani, Herbert Levine, Mohit Kumar Jolly

“…Summary: Cell-fate decisions involve coordinated genome-wide expression changes, typically leading to a limited number of phenotypes. …”
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Metabolic Syndrome and Triple-Negative Breast Cancer: A New Paradigm by Andrew A. Davis, Virginia G. Kaklamani

“…Specifically, increased leptin and decreased adiponectin levels disrupt homeostatic signaling pathways involved in cell proliferation, survival, cell-cycle regulation, and angiogenesis. …”
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Progress Research in the Immune-Actinopathies and Pathogenic Genes by MA Shiyun, ZHOU Lina, AN Yunfei, ZHAO Xiaodong

“…The mutations also affect the cytoskeleton and pseudopod formation; then they further affect the functions of immune cell, resulting in cell deformation, motility, phagocytosis, and adhesion. …”
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Resource Allocation for Vertical Sectorization in LTE-Advanced Systems by Lei Song, Mugen Peng, Yan Li

“…Compared with the conventional 2D MIMO scenarios, cell average throughput of the whole system can be improved by vertical sectorization. …”
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Il-6 signaling exacerbates hallmarks of chronic tendon disease by stimulating reparative fibroblasts by Tino Stauber, Greta Moschini, Amro A Hussien, Patrick Klaus Jaeger, Katrien De Bock, Jess G Snedeker

“…In this work, we screen cell signaling pathways in human tendinopathies and find positively enriched IL-6/JAK/STAT signaling alongside signatures of cell populations typically activated by IL-6 in other tissues. …”
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Application of in vitro and in vivo models in the study of food allergy by Jianjian Huang, Changjun Liu, Yanbo Wang, Chong Wang, Menghua Xie, Yi Qian, Linglin Fu

“…In this paper, we reviewed the common food allergy cell models including mast cell, basophil granulocyte and basophil, as well as the animal models of BALB/c mouse, C3H/HeJ mouse, and BN rat. …”
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Primary Lymphoma of the Liver: A Case Report and Review by Franzjosef Schweiger, Rowen Shinder, Sheldon Rubin

“…Biopsy confirmed that the tumour was of the diffuse large cell type and was of apparent T-cell origin. The diagnosis of these rare tumours is suggested by the presence of a hepatic mass without lymphadenopathy, splenomegaly or bone marrow involvement, as well as normal carcinoembryonic antigen and alpha-fetoprotein levels. …”
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PIDDosome Expression and the Role of Caspase-2 Activation for Chemotherapy-Induced Apoptosis in RCCs by Sebastian Heikaus, Igor Pejin, Helmut Erich Gabbert, Uwe Ramp, Csaba Mahotka

“…We, therefore, investigated their expression in renal cell carcinomas (RCCs) of the clear cell type in vivo and analysed the role of caspase-2 in chemotherapy-induced apoptosis in RCCs in vitro.…”
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