Crotalaria madurensis flavonol glycosides’ antibacterial activity against Staphylococcus aureus by Hala Sh. Mohammed, Salwa A. Abu El Wafa, Mona H. Ibrahim, Rasha Mohammad Fathy, Noha A. Seif-Eldein

“…Both the plant extract and metabolite 1 significantly reduced the viability and cell count of MRSA at concentrations of 1.0 and 0.5 mg/ml. …”
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WWTR1-AS1 LncRNA as a Novel Potential Diagnostic and Prognostic Biomarker in Breast Cancer by Mohadese Safabakhsh, Sohrab Boozarpour, Kamran Ghaedi, Mina Lashkarboloki, Shaaban Ghalandarayeshi

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The mechanism of enterogenous toxin methylmalonic acid aggravating calcium-phosphorus metabolic disorder in uremic rats by regulating the Wnt/β-catenin pathway by Xing Fan, Jing Li, Yan Gao, Lin Li, Haisong Zhang, Zhaoyu Bi

“…Additionally, rat glomerular podocytes were cultured, with cell viability and apoptosis measured. Results Intestinal flora richness and diversity in UR rats were decreased, along with unbalanced flora structure. …”
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Educating patients about health helps slow the progression of chronic kidney disease in the eastern region of India by Supriya Dasgupta, Reeti Debnath

“…Additionally, a higher prevalence of co-existing conditions such as diabetes mellitus and hypertension was noted among CKD patients, along with documented instances of polycystic kidney disease, obstructive uropathy, and renal cell carcinoma. After educating CKD patients, those who scored 8–10 on compliance exhibited a decrease in creatinine elevation (0.35 mg/dL) among 120 cases from January 2022 to June 2023. …”
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Assessment of The Impact of Apremilast on Levels of IL-17, IL-23, and Lipids in Obese Psoriatic Patient by Haitham M. Saad, Adil A. Noaimi, Halla Gh. Mahmood

“… Background: Psoriasis is an immune-mediated inflammatory disease with unknown aetiology that may be associated with the defect in proliferation and differentiation of the keratinocytes related to inflammatory cell infiltration. According to published reports, it is universal in occurrence; its prevalence in different populations varies from 0.1% to 11.8%. …”
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Molecular Detection and Isolation of Lumpy Skin Disease Virus during an Outbreak in West Hararghe Zone, Eastern Ethiopia by Umer Seid Geletu, Ahmedin Abdurehman Musa, Munera Ahmednur Usmael, Melaku Sombo Keno

“…Skin biopsy samples from 45 animals displaying clinical signs of LSD were inoculated in Vero cell lines because of limited equipment. After three blind passages, all samples developed cytopathic effects (CPEs). …”
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Effects of Traumeel (Tr14) on Exercise-Induced Muscle Damage Response in Healthy Subjects: A Double-Blind RCT by Kerstin Muders, Christian Pilat, Vanessa Deuster, Torsten Frech, Karsten Krüger, Jörn Pons-Kühnemann, Frank-Christoph Mooren

“…The Tr14 group showed a tendentially lower increase of neutrophils (p=0.10), BDNF (p=0.03), stem cell factor (p=0.09), and GM-CSF (p=0.09) to higher levels. …”
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Predictive value of epicardial fat thickness for left ventricular reverse remodeling after radiofrequency ablation in atrial fibrillation patients with left ventricular hypertrophy by Ke Hu, Wenhui Wang, Junping Zhen, Chunsong Kang

“…[Results] A total of 28 patients who did not achieve reverse remodeling were included in the control group, and 22 patients who achieved reverse remodeling were included in the reverse remodeling group.There were significant differences in age, atrial fibrillation classification, duration of atrial fibrillation, left atrial diameter (LAD), left ventricular end-diastolic diameter, left ventricular end-diastolic diameter index (LVEDI), neutrophil to lymphocyte ratio (NLR), high-sensitivity C-reactive protein (hsCRP), platelet distribution width(PDW), red cell distribution width, fibrinogen to albumin ratio (FAR) and EFT between the two groups (P<0.05).Multivariate logistic regression analysis showed that EFT, LAD, LVEDI, NLR, hsCRP, PDW and FAR were independent factors for left ventricular reverse remodeling(P<0.05).The cut-off value of EFT for predicting postoperative left ventricular reverse remodeling was 0.848, sensitivity was 95.5%, specificity was 89.3%, and AUC was 0.937 (95% CI: 0.868-0.983). …”
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Synthesis of Silver and Zinc Oxide Nanoparticles Using Polystichum lentum Extract for the Potential Antibacterial, Antioxidant, and Anticancer Activities by Deepak Kumar Shrestha, Akash Budha Magar, Manisha Bhusal, Rabina Baraili, Ishwor Pathak, Pusp Raj Joshi, Niranjan Parajuli, Khaga Raj Sharma

“…The nanoparticles also exhibit potent cytotoxicity with IC50 of 76.82 ± 1.67 μg/mL against cervical cancer cell lines. Both nanoparticles and aqueous extract were mildly toxic towards the brine shrimp nauplii with the lowest LC50 being 661.80 ± 64.21 μg/mL for the aqueous extract. …”
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Evaluation of Hematocrit in Adults with Dengue by a Laboratory Information System by Duangjai Sahassananda, Vipa Thanachartwet, Putza Chonsawat, Benjamaporn Wongphan, Supat Chamnanchanunt, Manoon Surabotsophon, Varunee Desakorn

“…Linear regression analysis indicated a significant relationship between Hgb and Hct with a coefficient of determination (Pearson’s R2) of 0.92 at red blood cell distribution width (RDW) ≤18, but Pearson’s R2 decreased to 0.78 at RDW >18. …”
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Markers of Anemia in Children with Type 1 Diabetes by Ewa Rusak, Anna Rotarska-Mizera, Piotr Adamczyk, Bogdan Mazur, Joanna Polanska, Agata Chobot

“…T1DM children had significantly higher red cell distribution width (RDW) (13.6 versus 12.6%; p<0.001), hepcidin (0.25 versus 0.12 ng/ml; p<0.001), and vitamin B12 concentrations (459 versus 397 pg/ml; p<0.01) and lower TIBC (59.09 versus 68.15 μmol/l; p<0.001) than in the control group. …”
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Microwave-assisted synthesis and swelling behavior of poly lactic acid (PLA) grafted Cordia dichotoma gum-based hydrogels by Jyoti Sinha, Abubakar Hamisu Mijinyawa, Faisal Islam Chowdhury, Muhd Zu Azhan Yahya, Pramod Kumar Singh, Geeta Durga

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PAROXYSMAL NOCTURNAL HEMOGLOBINURIA (PNH) DENGAN HYPERCOAGULABLE STATE by Fitrach Desfiyanda, Irza Wahid

“…Hal ini disebabkan oleh kelainan seluler karena mutasi somatik pada hematopoetic stem cell yang menyebabkan terjadinya defisiensi berbagai jenis protein yang diperlukan bagi pembentukan glycosylphosphatidylinositol (GPI) anchored, yakni antara lain yang tersering decay accelerating factor (DAF, CD55) dan membrane inhibitor of reactive lysis (MIRL, CD59). …”
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Transcriptomic Analysis of Pathogenicity Genes in Sclerotinia sclerotiorum Affecting Brassica napus by Hengameh Taheri, Mohamad Hamed Ghodoum Parizipour

“…These results demonstrated that S. sclerotiorum modulates some genes involved in disease induction (e.g., cell wall-degrading enzymes, biosynthesis of secondary metabolites & metabolic pathways) to infect its host plant.…”
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Internal transcribed spacer metagenomics data unravelling the core fungal community structure residing the wheat and maize rhizosphereNCBINCBINCBI by Sadia Latif, Rizwana Kousar, Anum Fatima, Naeem Khan, Hina Fatimah

“…Plants are colonized by a vast array of microorganisms that outstrip plant cell densities and genes, thus referred to as plant's second genome or extended genome. …”
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LIM-kinase 1 effects on memory abilities and male courtship song in Drosophila depend on the neuronal type by A. V. Zhuravlev, E. S. Zalomaeva, E. S. Egozova, A. D. Emelin, V. V. Sokurova, E. A. Nikitina, E. V. Savvateeva-Popova

“…At the same time, LIMK1 was observed in cell bodies, such as DAN clusters regulating memory formation in CCSP. …”
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Results of experimental infection of vaccinated and non-vaccinated ducklings with duck hepatitis virus by A. A. Chesnokova, E. V. Ivanova, V. V. Pronin, O. A. Chupina, V. Yu. Fomenko, M. S. Volkov, V. N. Irza

“…Pathomorphological studies carried out post experimental infection indicate that duck hepatitis virus induces pathogenic effect not only in birds’ digestive organs (the liver, in particular) but also causes degenerative changes in central and peripheral immune organs: in cloacal bursa, thymus and third eyelid gland, that may be manifested as deficiency of B- and T-cell immunity and requires further studies. It has been shown that in case of immunization of 3-day-old ducklings, the experimental vaccine induces antibody-mediated immune response, no harmful effect is produced on poultry if a tenfold dose is admin­istered which indicates its safety, and the vaccine ensures protection against infection with a control virulent strain of hepatitis virus.…”
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Identification of key genes associated with oxidative stress in ischemic stroke via bioinformatics integrated analysis by Gaiyan Li, Yu Cheng, Shanshan Ding, Qianyun Zheng, Lanqiong Kuang, Ying Zhang, Ying Zhou

“…Enrichment analysis indicated that the key genes were associated with oxidative stress, reactive oxygen species, lipid and atherosclerosis, and cell migration-related pathways. Then, 6 feature genes (HSPA8, NCF2, FOS, KLF4, THBS1, and HSPA1A) related to OS were identified for IS. …”
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Exploration of the molecular mechanism behind a novel natural genic male-sterile mutation of 1205A in Brassica napus by Lijing Xiao, Jinze Zhang, Shaomin Guo, Hairun Jin, Qingjing Ouyang, Xu Long, Zhongbin Yan, Entang Tian

“…Metabolic fluctuations associated with the fertility gene were observed, particularly in processes related to aborted tapetal programmed cell death (PCD), which may contribute to reduced pollen fertility with abnormal pollen exine. …”
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Outcomes of Six-Dose High-Dose Cytarabine as a Salvage Regimen for Patients with Relapsed/Refractory Acute Myeloid Leukemia by Brandi Anders, Lauren Veltri, Abraham S. Kanate, Alexandra Shillingburg, Nilay Shah, Michael Craig, Aaron Cumpston

“…Relapsed/refractory acute myeloid leukemia (RR-AML) is associated with poor prognosis and long-term disease-free survival requires allogeneic hematopoietic cell transplantation (allo-HCT). Limited data exists, regarding the optimal regimen to obtain remission prior to allo-HCT. …”
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