Seasonal Pattern of Endo-β-Mannanase Activity During Germination of <i>Jeffersonia dubia</i>, Exhibiting Morphophysiological Dormancy by Young Hyun Kwon, Seung Youn Lee, Yong Ha Rhie

“…Erosion of the endosperm cell wall was observed in the lateral regions surrounding the embryo, whereas the micropylar endosperm showed no obvious signs of collapse or damage. …”
Get full text

Effects of Gamma Irradiation on the Properties of Hydroxyapatite-Collagen-Chitosan-Mg-ZnO Scaffolds for Bone Tissue Engineering by Tusher -Al-Arafat, Shawon Ahmed, Polash Chandra Karmakar, Umme Salma Zohora, Naznin Akhtar, S. M. Asaduzzaman

“…Moreover, the irradiated and nonirradiated scaffolds were biocompatible and noncytotoxic toward the Vero cell line which ensured their suitability for use in vivo. …”
Get full text

Oxidative stress and inflammation in hemodialysis: a comparison of patients with or without advanced nonalcoholic fatty liver disease (NAFLD) by Vanja Kalacun, Robert Ekart, Sebastjan Bevc, Pavel Skok, Radovan Hojs, Nina Vodošek Hojs

“…There was no significant difference in high-sensitivity C-reactive protein (hs-CRP), and vascular cell adhesion molecule 1 (VCAM-1) between groups. …”
Get full text

EFFECTS OF MODERATELY VIRULENT AFRICAN SWINE FEVER VIRUS ON INTERLEUKIN-10 PRODUCTION by A. S. Pershin, I. V. Shevchenko, A. S. Igolkin, Ye. V. Aronova, N. N. Vlasova

“…For this, 12 piglets were experimentally infected intramuscularly with a continuous cell culture-adapted ASFV isolate Vero25 at a dose of 10 HAdU per animal followed by control infection of surviving animals with the reference virus isolate Arm 07 at a dose of 1,000 HAdU per animal. …”
Get full text

Multigene Panel Testing in Turkish Hereditary Cancer Syndrome Patients by Esra ARSLAN ATES, Ayberk TURKYILMAZ, Ceren ALAVANDA, Ozlem YILDIRIM, Ahmet Ilter GUNEY

“…Objective: Hereditary cancer syndromes (HCSs) are a heterogenous group of disorders caused by germline pathogenic variations in various genes that function in cell growth and proliferation. This study aimed to describe the germline variations in patients with hereditary cancer using multigene panels. …”
Get full text

Review of the potential of bioactive compounds in seaweed to reduce histamine formation in fish and fish products by Muhammad Maskur, Asep Awaludin Prihanto, Muhamad Firdaus, Rovina Kobun, Rahmi Nurdiani

“…The bioactive compounds considered, such as flavonoids, alkaloids, terpenes, and phenolic acids, exhibit their antibacterial effects through various mechanisms, including the inhibition of DNA and RNA synthesis, disruption of cytoplasmic and cell membranes, and inhibition of enzymes by reacting with sulfhydryl groups on proteins. …”
Get full text

Mycobacterium spp. exposure, childhood vaccinations, and early childhood brain and CNS cancers by Samer Singh, Rakesh K. Singh

“…However, interestingly, prevailing tuberculin immunoreactivity, a surrogate for the existence of heterologous cell-mediated immunity resulting from exposure to Mycobacterium spp., including Bacille Calmette-Guérin (BCG) vaccination, for these populations, is found consistently negatively correlated with the BCNS cancer incidence in 0-4Y-olds for countries mandating neonatal BCG vaccination [r(24): -0.7226, p-value:&lt;0.0001]. …”
Get full text

Site-selective photo-crosslinking for the characterisation of transient ubiquitin-like protein-protein interactions. by Zac Sandy, Zijuan Wang, Deepak Behera, Benjamin M Foster, Finlay A Martin, Kira Brüninghoff, Kathleen M Cain, Wolfgang Dörner, Maria Jose Cabello-Lobato, Josep V Forment, Matthew J Cliff, Igor Larrosa, Perdita Barran, Duncan L Smith, Henning D Mootz, Christine K Schmidt

“…Taken together, the approach opens the possibility of characterising previously undetected protein-protein interactions, with the potential of elucidating molecular mechanisms behind the most complex and poorly understood processes in the cell.…”
Get full text

E-Selectin/AAV Gene Therapy Promotes Myogenesis and Skeletal Muscle Recovery in a Mouse Hindlimb Ischemia Model by Antoine J. Ribieras, Yulexi Y. Ortiz, Yan Li, Nga T. Le, Carlos T. Huerta, Francesca A. Voza, Hongwei Shao, Roberto I. Vazquez-Padron, Zhao-Jun Liu, Omaida C. Velazquez

“…E-selectin is an adhesion molecule that mediates cell recruitment during neovascularization. Therapeutic priming of ischemic limb tissues with intramuscular E-selectin gene therapy promotes angiogenesis and reduces tissue loss in a murine hindlimb gangrene model. …”
Get full text

Efficacy and safety of immunotherapy in locally advanced or metastatic pulmonary lymphoepithelioma-like carcinoma: a multicenter retrospective study by Xiongwen Yang, Yi Xiao, Yubin Zhou, Hao Hu, Huiyin Deng, Jian Huang, Maoli Liang, Zihao Yuan, Longyan Dong, Shaohong Huang

“…Background: Pulmonary lymphoepithelioma-like carcinoma (pLELC) is a rare subtype of non-small-cell lung cancer that predominantly affects younger, non-smoking individuals in southern and southeast Asia, where Epstein–Barr virus (EBV) prevalence is high. …”
Get full text

Weakly Supervised Nuclei Segmentation with Point-Guided Attention and Self-Supervised Pseudo-Labeling by Yapeng Mo, Lijiang Chen, Lingfeng Zhang, Qi Zhao

“…Despite great progress, two challenges hinder the performance of weakly supervised nuclei segmentation methods: (1) The stable and effective segmentation of adjacent cell nuclei remains an unresolved challenge. (2) Existing approaches rely solely on initial pseudo-labels generated from point annotations for training, and inaccurate labels may lead the model to assimilate a considerable amount of noise information, thereby diminishing performance. …”
Get full text

Zoonotic Babesia: A scoping review of the global evidence. by Kaitlin M Young, Tricia Corrin, Barbara Wilhelm, Carl Uhland, Judy Greig, Mariola Mascarenhas, Lisa A Waddell

“…Articles described a variety of study designs used to study babesiosis in humans and/or zoonotic Babesia species in vectors, animal hosts, and in vitro cell cultures. Topics of study included: pathogenesis (680 articles), epidemiology (480), parasite characterization (243), diagnostic test accuracy (98), mitigation (94), treatment (65), transmission (54), surveillance (29), economic analysis (7), and societal knowledge (1). …”
Get full text

Incorporation of recombinant proteins into extracellular vesicles by Lactococcus cremoris by Tina Vida Plavec, Kristina Žagar Soderžnik, Giulia Della Pelle, Špela Zupančič, Robert Vidmar, Aleš Berlec

“…In contrast to mammalian cell-derived EVs, the study of EVs from bacteria, particularly Gram-positive bacteria, received less research attention. …”
Get full text

Carbon Monoxide Poisoning with Neurological, Ocular, and Myocardial Damage: A Case Report by Duc Nguyen, Sinh Nguyen, Anh Lam

“…CO has a high affinity with hemoglobin because it reduces oxygen transport causing tissue hypoxia, lactic acidosis, and cell death.Case report: A 32-year-old female patient entered Poison Control Center of Bach Mai Hospital, Ha Noi, Vietnam, because of decreased consciousness, loss of vision in the right eye. …”
Get full text

Eastern equine encephalitis virus: Pathogenesis, immune response, and clinical manifestations by Bhumika Parashar, Rishabha Malviya, Sathvik Belagodu Sridhar, Tarun Wadhwa, Sirajunisa Talath, Javedh Shareef

Get full text

Influence of Fasting Plasma Glucose Level on Admission of COVID-19 Patients: A Retrospective Study by Yingying Zhao, Huichun Xing

“…We found that elevated FPG levels were correlated with longer duration of SARS-CoV-2 RNA positivity, classification of COVID-19, imaging changes of chest CT, inflammation-related biomarkers, and CD8+ T cell number in COVID-19 patients. In a logistic regression model, after adjusting for gender and age, COVID-19 patients with elevated FPG were more likely to had longer duration of SARS-CoV-2 RNA positivity than those with normal FPG levels (OR 3.053 [95% CI 1.343, 6.936]). …”
Get full text

Monacolin K as a Natural Alternative for Synthetic Statins by Julia Kozakiewicz, Aleksandra Okońska, Michał Ziemba, Kamil Kościelecki, Agnieszka Kalisz, Magdalena Krakowiak, Aleksandra Kaczmarek

“…Monacolin K has many pleiotropic effects like anti-inflammatory and anti-cancer mechanisms by inhibiting  cancer cell proliferation and stimulating apoptosis. It should be emphasized that the long-term safety of regular use of these preparations has not been fully documented. …”
Get full text

Prognostic Value of TRPM7 Expression and Factor XIIIa-Expressing Tumor-Associated Macrophages in Gastric Cancer by Muhammet Calik, Ilknur Calik, Gokhan Artas, Ibrahim Hanifi Ozercan

“…TRPM7 is known to play a key role in tumor progression by regulating cellular proliferation, migration, and invasion in various cancer cell lines. However, there are no comprehensive clinical studies about the effect of TRPM7 expression on gastric cancer (GC) prognosis. …”
Get full text

Learning-induced sensory plasticity of mouse olfactory epithelium by A. V. Romashchenko, Р. Е. Kireeva, M. В. Sharapova, Т. A. Zapara, A. S. Ratushnyak

“…In our experiment, associative learning led to changes in the patterns of OE cell activation in response to orange oil in comparison with the control group and animals that were given odor without reinforcement. …”
Get full text

STICI: Split-Transformer with integrated convolutions for genotype imputation by Mohammad Erfan Mowlaei, Chong Li, Oveis Jamialahmadi, Raquel Dias, Junjie Chen, Benyamin Jamialahmadi, Timothy Richard Rebbeck, Vincenzo Carnevale, Sudhir Kumar, Xinghua Shi

Get full text