The prevalence of hypermobile Ehlers–Danlos syndrome at a gender-affirming primary care clinic by Theo Stein, Shannon Collins, Joshua St. Louis

“…Within the sample of patients with hypermobile Ehlers–Danlos syndrome, 81.4% were found to have diagnoses of anxiety, depression, or attention deficit hyperactivity disorder, 50.8% had a history of migraines or dysautonomia, 39.0% had a history of gastroesophageal reflux disease, irritable bowel syndrome, nausea, diarrhea, or gastroparesis, 16.9% had history of mast cell activation disorder, 32.2% had postural orthostatic tachycardia syndrome, 30.5% had dysmenorrhea, 83.1% reported chronic pain, and 44.1% reported chronic fatigue. …”
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Network pharmacology combined with experimental verification for exploring the potential mechanism of phellodendrine against depression by Lili Hu, Na Wu, Jue Wang, Donghui Cai

“…The mitochondrial DNA (mtDNA) copy number, inflammatory cytokines and pathway-related mRNA expressions in PC12 cell were determined via quantitative PCR (qPCR) and enzyme-linked immunosorbent assay to verify our finding. …”
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Extending Integration: Interventions Supporting Communication and Collaboration Between Patients with Neurological Diseases, Their Informal Caregivers and Healthcare Staff – a Scop... by Eskil Degsell, Lina Al-Adili, Petter Gustavsson, Mats Brommels, Petra Dannapfel

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Teeth Structure Analysis of Primary Teeth in Children with Congenital Heart Disease (Ventricular Septal Defect) in Erbil City by Huda Raad Mahdi, Omed Ikram Shihab

“…The number of odontoblast cell layers between groups was significantly higher in group I (7.32±33.28, and 3.807±11.94) respectively(P<0.0001). …”
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The Importance of C4d in Biopsies of Kidney Transplant Recipients by Rosana Rosa Miranda Corrêa, Juliana Reis Machado, Marcos Vinícius da Silva, Fernanda Rodrigues Helmo, Camila Souza Oliveira Guimarães, Laura Penna Rocha, Ana Carolina Guimarães Faleiros, Marlene Antônia dos Reis

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Injectable Self-Assembling Procyanidin Nanospheres for Effective Osteoarthritis Treatment by Li G, He F, Feng J, Xu G, Wu C, Qiao Y, Liu Y, Chen H, Du P, Wang J

“…Current treatment methods primarily rely on analgesics or anti-inflammatory drugs to alleviate symptoms but fail to achieve the desired therapeutic outcome.Methods: To better realize therapeutic effects of OA, procyanidins (PAs), as a type of plant flavonoids with strong antioxidant and anti-inflammatory activities, were designed to self-assembly with well-dispersible Pluronic F127 (PF127) through the hydrogen-bond interaction to present an injectable, biocompatibility PA nanospheres.Results: These nanospheres significantly increased the cell viability in mouse L929 fibroblasts and ADTC5 chondrocytes compared with unassembled PAs. …”
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Fluctuations Driven by Multicomponent Pickup Ion Distributions in the Outer Heliosheath by Ameneh Mousavi, Vadim Roytershteyn, Federico Fraternale, Nikolai Pogorelov

“…Moreover, several 1D and 2D hybrid simulations with different numbers of particles per cell are performed to examine the impact of numerical noise on PUI scattering. …”
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Naturally russeted and wound russeted skins of mango (cv. ‘Apple’) show no differences in anatomy, chemical composition or gene expression by Jannis Straube, Thomas O. Athoo, Viktoria Zeisler-Diehl, Kiran Suresh, Lukas Schreiber, Moritz Knoche

“…Wound-induced periderms had more cell layers and a higher mass than natural periderms. …”
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Inflamm-Aging Is Associated with Lower Plasma PTX3 Concentrations and an Impaired Capacity of PBMCs to Express hTERT following LPS Stimulation by Aaron L. Slusher, Tiffany M. Zúñiga, Edmund O. Acevedo

“…Age-related elevations in proinflammatory cytokines, known as inflamm-aging, are associated with shorter immune cell telomere lengths. Purpose. This study examined the relationship of plasma PTX3 concentrations, a biomarker of appropriate immune function, with telomere length in 15 middle-aged (40-64 years) and 15 young adults (20-31 years). …”
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The Fate of the Tumor in the Hands of Microenvironment: Role of TAMs and mTOR Pathway by Danilo Figueiredo Soave, Marina Pacheco Miguel, Fernanda Dias Tomé, Liliana Borges de Menezes, Patrícia Resende Alo Nagib, Mara Rúbia Nunes Celes

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Role of Serum Amyloid A as a Biomarker for Predicting the Severity and Prognosis of COVID-19 by Amal A. Abbas, Asma Alghamdi, Sonia Mezghani, Mourad Ben Ayed, Ahmed M. Alamori, Ghazi A. Alghamdi, Wail Bajhmom, Hanan Wajeeh, Salma S. Almutairi, Wafaa M. Radwan

“…Dynamic shifts in SAA, C-reactive protein (CRP), white blood cell (WBC), lymphocytes, neutrophils, biochemical markers, and disease progression were examined. …”
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A Polymer-Binder-Free Approach to Creating Functional LiFePO₄ Cathodes by Organic Ionic Plastic Crystal-Derived Ion-Conductive Binders by Daniela M. Josepetti, Maria Forsyth, Patrick C. Howlett, Hiroyuki Ueda

“…Preliminary battery tests with a limited Li⁺ source demonstrated the feasibility of full-cell operation without using the lithium-metal anode. …”
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The value of increasing sequencing depth for noninvasive prenatal screening for whole chromosomal aneuploidy by Dongmei Wang, Fangfang Guo, Yaping Hou, Haishan Peng, Tingting Hu, Jiexia Yang

“…This study recruited a cohort of 59,800 singleton pregnancies from Guangdong Women and Children Hospital between January 2015 and December 2020, including 48,018 cases of NIPT and 11,782 cases of expanded NIPT. Cell-free DNA from plasma samples was sequenced at a sequencing depth of 0.15X for NIPT and 0.4X for expanded NIPT. …”
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Serum Glucose-Dependent Insulinotropic Polypeptide (GIP) and Glucagon-Like Peptide-1 (GLP-1) in association with the Risk of Gestational Diabetes: A Prospective Case-Control Study by Maryam Mosavat, Siti Zawiah Omar, Sajad Jamalpour, Peng Chiong Tan

“…In the postpuerperium, when there is a drop in β-cell function, participants with previous GDM (pGDM) presented lower GLP-1 (in both GDM subgroups) and lower GIP in GDM-diet subgroup compared to controls. …”
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Best practices in the management of thyroid dysfunction induced by immune checkpoint inhibitors by Ichiro Yamauchi, Daisuke Yabe

“…There is evidence that overt thyroid irAEs are associated with good prognosis, at least in non-small cell lung cancer. Although the clinical features have been well clarified, the management strategies require further refinement. …”
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Corneal Safety and Stability in Cases of Small Incision Lenticule Extraction with Collagen Cross-Linking (SMILE Xtra) by Ihab Mohamed Osman, Hany Ahmed Helaly, Mohsen Abou Shousha, Amir AbouSamra, Islam Ahmed

“…Outcome data were recorded including uncorrected distance visual acuity and corrected distance visual acuity (UDVA and CDVA), manifest refraction spherical equivalent (MRSE), central corneal thickness, average keratometry, endothelial cell density, corneal resistance factor (CRF), and corneal densitometry. …”
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Molecular genetic bases of seed resistance to oxidative stress during storage by N. A. Shvachko, E. K. Khlestkina

“…The data on the destructive effect of free radicals towards plant cell macromolecules are analyzed, and the ways to eliminate excessive ROS in plants, the most important of which is the glutathioneascorbate pathway, are discussed. …”
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Definition of a Novel Cuproptosis-Relevant lncRNA Signature for Uncovering Distinct Survival, Genomic Alterations, and Treatment Implications in Lung Adenocarcinoma by Zhuning Wang, Junqiao Yao, Tengyu Dong, Xing Niu

“…Cuproptosis is a newly discovered copper-independent cell death modality, and limited evidence suggests the critical implications in human cancers. …”
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Anti-constitutional activities and cover organisations of national-socialist movement in Klaipėda region in 1935-1937 by Mindaugas Valiukevičius

“…Around 1000 block and cell leaders remained free and carried on with their activities. …”
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The Unforeseen Diagnosis: Hyperparathyroidism-Jaw Tumour Syndrome Case Report and Review of the Literature by Maxim Barnett, Farhan Ahmed, Radu Mihai, Asha Rattan, Malik Asif Humayun

“…Hyperparathyroidism-jaw tumour syndrome is one such autosomal dominant familial disorder, characterised by a mutation in the cell division cycle 73 (CDC73; also known as HRPT-2) tumour suppressor gene. …”
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