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22061
Tackling Microbial Resistance and Emerging Pathogens with Next-Generation Antibiotics
Published 2024-08-01“…Mechanisms include increased drug adhesion to bacterial cell walls, generating oxidative stress, and causing mistranslation by detaching ribosomes from tRNA. …”
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22062
The Role of Local and Upstream Colonisation in Determining Stream Periphyton Metacommunity Assemblages
Published 2025-01-01“…Control samples showed 1.5–6 times higher cell densities than plastic‐cover samples, suggesting that local colonisation is very important for biomass accrual. …”
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22063
Bifunctional electrocatalytic performance of MgAlCe-LDH/β-Ni(OH)2/Ni foam in total natural seawater splitting
Published 2025-01-01“…Implementing a two-electrode configuration for the MgAlCe-LDH/β-Ni(OH)2/Ni foam, the total seawater splitting investigation exhibits 1.42 V cell voltage at a current density of 10 mA cm−2 and 25 h long-term stability.…”
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22064
Corneal edema after cataract surgery in diabetic and non-diabetic patients
Published 2024-06-01“…Patients with diabetes mellitus undergoing phacoemulsification cataract surgery face an elevated risk of corneal edema, primarily due to metabolic disturbances that impair endothelial cell function, leading to delayed post-operative recovery. …”
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22065
The role of human leukocyte antigen in HTLV-1 infection and progression to ATLL and HAM/TSP: a systematic review and meta-analysis
Published 2025-01-01“…Abstract Background Human T-cell lymphotropic virus type 1 (HTLV-1) is a retrovirus that leads to lifelong infection and multiple diseases, including HAM/TSP and ATLL. …”
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22066
Expression profiles of long and short RNA s in the cytoplasm and nuclei of growing chicken (Gallus gallus domesticus) oocytes
Published 2015-07-01“…Maternal RNAs accumulated during oocyte maturation are required not only for zygote formation but also for supporting the first embryonic cell divisions until embryo genome activation. Essential stages of transcriptome analysis include adaptation of RNA extraction procedures and characterization of the RNA expression profile. …”
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22067
Modifying non-coding regions of linear DNA vaccines to explore the interplay of expression and inflammation in immunogenicity
Published 2025-12-01“…Here, we explore the effect of altering non-coding 5’ regions, on the immunogenicity of a closed linear DNA platform, Doggybone™ DNA (dbDNATM), produced by a rapid and scalable cell-free method. Using a mouse model, we found that enhancer sequences and DNA targeting sequences (DTS) increased influenza virus hemagglutinin (HA) expression and improved immune responses. …”
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22068
Utilizing MRAMs With Low Resistance and Limited Dynamic Range for Efficient MAC Accelerator
Published 2024-01-01“…Although ultra-dense magnetic memories with multi-bit capability (MLC) were proposed recently, their application in hybrid CMOS-non-volatile memory accelerators is limited due to their low dynamic range (memory window) and high cell currents (ON/OFF-state resistance in ∼kΩ). …”
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22069
Molecular Mechanisms Contributing Bacterial Infections to the Incidence of Various Types of Cancer
Published 2020-01-01“…It has been found that inflammations induced cancer via different mechanisms including induction of cell proliferation and production of high levels of free radicals. …”
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22070
Awardee Summary of 2023 Taiwan Oncology Society Clinical Research Award Recipient: Persistent Endeavors on Research of Digestive Cancers for Three Decades
Published 2024-01-01“…Second, we have made persistent efforts in translational research and clinical trials on early-stage gastric mucosa-associated lymphoid tissue lymphomas (MALTomas), gastric diffuse large B-cell lymphomas, colorectal cancers (CRCs), pancreatic cancers, and immuno-oncology. …”
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22071
Clinical and Morphological Manifestations of Gastritis and Serum Cytokine Levels in Schoolchildren with Familial History of Gastric Cancer
Published 2021-10-01“…In positive history and negative H. pylori tests, the cell immune response regulator IL-18 37 was revealed elevated in histology. …”
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22072
Research on Integrated Control Strategy for Highway Merging Bottlenecks Based on Collaborative Multi-Agent Reinforcement Learning
Published 2025-01-01“…The proposed Factored Multi-Agent Centralized Policy Gradients for Integrated Traffic Control in Dynamic Areas (FM-ITC-Darea) control strategy is simulated and tested on a multi-ramp scenario built on a multi-lane Cell Transmission Model (CTM) simulation platform. …”
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22073
Traffic Risk Assessment Based on Warning Data
Published 2022-01-01“…The data of bus vehicle warnings in Zhenjiang, Jiangsu Province, are employed as an example for validation. The geographic cell of 1 km × 1 km scale is applied as the basic risk assessment unit. …”
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22074
Chloride Ingress in Cement Mortars Exposed to Acidithiobacillus thiooxidans Bacteria
Published 2020-01-01“…Acidithiobacillus thiooxidans bacterial solution of concentration 1.0×107 cell/mL was used to prepare microbial mortar prisms, whereas distilled water was used to prepare the control mortar prisms. …”
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22075
Burden of scabies in a Ghanaian penitentiary.
Published 2024-01-01“…Among males, the median (IQR) number of persons per cell was 115 (56-118) and 7 (7-8) for female prisoners. 79.2% of 96 individuals previously treated in the preceding two months still demonstrated skin manifestations of scabies. …”
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22076
Antigen Delivery Platforms for Next-Generation Coronavirus Vaccines
Published 2024-12-01“…The development of a pan-CoV vaccine offering protection against a wide array of VOCs requires two key elements: (1) identifying protective antigens that are highly conserved between passed, current, and future VOCs; and (2) developing a safe and efficient antigen delivery system for induction of broad-based and long-lasting B- and T-cell immunity. This review will (1) present the current state of antigen delivery platforms involving a multifaceted approach, including bioinformatics, molecular and structural biology, immunology, and advanced computational methods; (2) discuss the challenges facing the development of safe and effective antigen delivery platforms; and (3) highlight the potential of nucleoside-modified mRNA encapsulated in lipid nanoparticles (LNP) as the platform that is well suited to the needs of a next-generation pan-CoV vaccine, such as the ability to induce broad-based immunity and amenable to large-scale manufacturing to safely provide durable protective immunity against current and future Coronavirus threats.…”
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22077
Inferring Tripartite Associations of Vector-Borne Plant Pathogens Using a Next-Generation Sequencing Approach
Published 2025-01-01“…Phytoplasmas are a group of plant-pathogenic, cell-wall-less bacteria vectored primarily by leafhoppers (Hemiptera Cicadellidae), one of the most diverse families of insects. …”
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22078
Exploring RNA-Seq Data Analysis Through Visualization Techniques and Tools: A Systematic Review of Opportunities and Limitations for Clinical Applications
Published 2025-01-01“…We found that 18% of studies have visualization techniques and tools for circular RNA-seq data, 56% for single-cell RNA-seq data, 23% for bulk RNA-seq data, and 3% for long non-coding RNA-seq data. …”
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22079
Microplastic and human health with focus on pediatric well-being: a comprehensive review and call for future studies
Published 2025-01-01“…This study thoroughly summarized how MP exposure in children of all ages causes cell damage and leads to adverse health effects such as cancer. …”
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22080
Beyond periodicity: tailoring Tamm resonances in plasmonic nanohole arrays for multimodal lasing
Published 2025-01-01“…However, these resonances vanish when the hole arrangement shifts from a regular array to a pseudo-periodic random array, which is defined as a collection of holes placed randomly within a periodically repeating square unit cell. These multiple resonances can be attributed to the folding of dispersion lines in a periodically patterned TP cavity. …”
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