Glutathione S-transferase polymorphism in ethnic groups living in Eastern Siberia by E. V. Belyaeva, O. A. Yershova, T. A. Astahova, O. V. Bugun

“…The role of glutathione S-transferase for the life of the cell and the entire organism is related to their participation in the processes of detoxification of xenobiotics and antioxidant protection. …”
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Butein Inhibits Oxidative Stress Injury in Rats with Chronic Heart Failure via ERK/Nrf2 Signaling by Peng Liu, Quanli Pan

“…Hematoxylin and eosin (H&E) staining was used to observe the myocardial cell morphology. The effect of butein on the extracellular signal-regulated kinase (ERK)/nuclear factor-E2 p45-related factor (Nrf2) signaling was confirmed by Western blot analysis. …”
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Golden Tandem of Photothermal Ablation and Simultaneous Anti-Inflammation in One Nanoparticle for Activated Macrophage-Targeted Atherosclerosis Treatment by Lu Y, Wang Y, Li Y, Li Y, Jiang YW, Li J

“…The preparation and characterization of GSNPD, their cellular toxicity, photothermal conversion and targeted ablation efficiency, anti-inflammation and ROS scavenging effect, as well as the inhibition of foam cell formation were studied in vitro.Results: The experimental results showed that the fabricated GSNPD NPs displayed positive effects on anti-atherosclerosis by pro-inflammatory macrophages ablation, NO production and ROS scavenging.Discussion: GSNPD NPs were designed to effectively and accurately ablate pro-inflammatory macrophages by recognizing and targeting to SR-A overexpressed on the activated macrophages of arterial plaques via PTT, and simultaneous inhibit the PTT-induced inflammation through the laser-activated NO release in situ. …”
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The impact of PD-L1 polymorphisms on the efficacy of immune checkpoint inhibitors depends on the tumor proportion score: a retrospective study by Keiichiro Suminaga, Takashi Nomizo, Hironori Yoshida, Hiroaki Ozasa

“…Method Patients treated with immune checkpoint inhibitor monotherapy for non-small cell lung cancer at Kyoto University Hospital until January 2023, with TPS data and biological specimens available for SNP measurement, were eligible for this study. …”
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Lessons from SARS-CoV, MERS-CoV, and SARS-CoV-2 Infections: What We Know So Far by Radi Taha Alsafi

“…Therefore, this review summarizes the state-of-the-art information and compares the similarities and dissimilarities between SARS-CoV, MERS-CoV, and SARS-CoV-2, in terms of their evolution trait, genome organization, host cell entry mechanisms, tissue infectivity tropisms, transmission routes and contagiousness, and the clinical characteristics, laboratory features, and immunological abnormalities of their related illnesses. …”
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Cholestatic Hepatocellular Injury with Azathioprine: A Case Report and Review of the Mechanisms of Hepatotoxicity by Joseph Romagnuolo, DC Sadowski, E Lalor, L Jewell, ABR Thomson

“…The cases reported to date can be grouped into three syndromes: hypersensitivity; idiosyncratic cholestatic reaction; and presumed endothelial cell injury with resultant raised portal pressures, veno-occlusive disease or peliosis hepatis. …”
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Identification of Suitable Natural Inhibitor against Influenza A (H1N1) Neuraminidase Protein by Molecular Docking by Maheswata Sahoo, Lingaraja Jena, Surya Narayan Rath, Satish Kumar

“…It is responsible for sialic acid cleavage from glycans of the infected cell. We employed amino acid sequence of H1N1 NA to predict the tertiary structure using Phyre2 server and validated using ProCheck, ProSA, ProQ, and ERRAT server. …”
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Spectral Investigation and In Vitro Antibacterial Evaluation of NiII and CuII Complexes of Schiff Base Derived from Amoxicillin and α-Formylthiophene (αft) by Narendra Kumar Chaudhary, Parashuram Mishra

“…The structure optimization by molecular mechanics (MM) force field calculation through ArgusLab 4.0.1 version software also supports the concerned geometry of the complexes. The cell dimensions as suggested by XRPD study, a (6.753 Å), b (13.904 Å), c (20.122 Å), α (142.76°), β (106.580°), and γ (72.4343°) for CuII and a (24.2547 Å), b (6.6371 Å), c (5.5047 Å) (α = β = γ = 90°) for NiII complexes, are in good agreement with their triclinic and orthorhombic crystal systems. …”
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Evaluation of Antidiabetic Properties of the Leaves Extract of Ficus vallis-choudae Delile in a Model of Type 2 Diabetes Induced by High-Fat Diet and Streptozotocin by Kilenma Kolefer, David Miaffo, Roger Ponka

“…In addition, it dramatically reduced body mass, body mass index (BMI), atherogenic index (AI), coronary heart risk index (CRI), and abdominal fat and increased homeostatic model assessment of β-cell function (HOMA-β), high-density lipoprotein cholesterol (HDL-c) levels, and cardioprotective index (CI). …”
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Prevalence of Esophageal Eosinophilia, Eosinophilic Esophagitis, and Lymphocytic Gastritis in Children with Celiac Disease: A Saudi Tertiary Center Experience by Meshari A. Alaifan, Ammar Khayat, Rana Y. Bokhary, Abdulhameed Ibrahim, Yagoub Bin-Taleb, Bakr H. Alhussaini, Omar I. Saadah

“…The esophageal biopsy results reported were basal cell hyperplasia in 24 patients (32.9%), esophageal eosinophilia in 23 patients (31.5%), and EoE in 3 patients (4.1%). …”
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Unveiling the Hidden Burden: Estimating All-Cause Mortality Risk in Older Individuals with Type 2 Diabetes by Dikang Pan, Hui Wang, Sensen Wu, Jingyu Wang, Yachan Ning, Jianming Guo, Cong Wang, Yongquan Gu

“…The final model includes four independent predictors: age, gender, estimated glomerular filtration rate, and white blood cell count. The C-index values for the training and validation cohorts were 0.748 and 0.762, respectively. …”
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Immunotherapy in the Treatment of Metastatic Melanoma: Current Knowledge and Future Directions by Massimo Ralli, Andrea Botticelli, Irene Claudia Visconti, Diletta Angeletti, Marco Fiore, Paolo Marchetti, Alessandro Lambiase, Marco de Vincentiis, Antonio Greco

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ИССЛЕДОВАНИЯ ВЛИЯНИЯ ТЕРМИЧЕСКИХ ОБРАБОТОК НА ПОКАЗАТЕЛИ КАЧЕСТВА ИГРИСТЫХ ВИН by Татьяна Александровна Дроздова, Наталья Михайловна Агеева, Максим Витальевич Поспелов

“…This value was achieved due to the breakdown of protein structures of the yeast cell and increased activity of hydrolytic enzymes, which contributed to an increase in the concentration of amine nitrogen from 157.5 to 161.0 mg/dm3, which are surfactants. …”
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Prevalence, Severity, and Determinant Factors of Anemia among Pregnant Women in South Sudanese Refugees, Pugnido, Western Ethiopia by Aklilu Alemayehu, Lealem Gedefaw, Tilahun Yemane, Yaregal Asres

“…Complete blood count was done using CELL-DYN 1800 (Abbott USA). Blood smear and fecal specimen were examined for hemoparasite and intestinal parasite, respectively. …”
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Exploring the Effect of Mechanical Damage on the Water State in Blueberries Using Low-Field Nuclear Magnetic Resonance Spectroscopy by LUO Zixuan, JIANG Fengli, WU Peijing, SONG Ping, DING Keke

“…The results demonstrated a significant impact of injury on the water state and distribution of blueberries. Notably, the cell wall water content A21 decreased, whereas the cytoplasm water content A22 increased over time post-damage. …”
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Reproduction of Local Strong Wind Area Induced in the Downstream of Small-Scale Terrain by Computational Fluid Dynamic (CFD) Approach by Takanori Uchida, Keiji Araki

“…It was clarified that in order to simulate the air flow characteristic of the separated flow originating from the small-scale terrain (at an altitude of approximately 180 m) targeted in the present research, approximately 10 m of spatial resolution of computational cell in the horizontal direction is required. In addition, the effect of stable stratification on the flow was also examined. …”
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Shear Bond Strength of Colored and Sandblasted Zirconia to Ceramic Veneers Fabricated by the Pressing and Layering Techniques: An In Vitro Study by Mahsa Abbasi, Behnaz Ebadian, Negin Aminianpour

“…The specimens underwent 10,000 thermal cycles between 5 and 55°C, and their biaxial SBS was measured in an electromechanical universal test machine (0.5 mm/min with 2.5 kN load cell). The failure mode was also assessed under a stereomicroscope. …”
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Exploring Unique Extracellular Vesicles Associated Signatures: Prognostic Insights, Immune Microenvironment Dynamics, and Therapeutic Responses in Pancreatic Adenocarcinoma by Kai Nan, Ming Zhang, Zilong Geng, Yuankai Zhang, Lin Liu, Zhi Yang, Peng Xu

“…Conversely, heightened expression of TRHED-AS1 was associated with compromised immune cell infiltration and diminished responsiveness to immunotherapy. …”
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The Haematological Effects of Oleanolic Acid in Streptozotocin-Induced Diabetic Rats: Effects on Selected Markers by Charity M. Baloyi, A. Khathi, Ntethelelo H. Sibiya, Phikelelani S. Ngubane

“…The reduction of blood glucose concentration, HbA1c, and improved EPO concentrations was further associated with a notable increase in red blood cell (RBC) count and other RBC indices. We also observed an increase in the antioxidant status of the RBCs with a concomitant decrease in oxidative stress. …”
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Bax/Bcl-2 Expression Ratio Analysis of Rat Ovary Vitrified with Date Juice Concentrate as a Natural Extracellular Cryoprotectant by Aisyah Safrina, Nova Anita, Ahmad Aulia Jusuf, Rahimi Syaidah, Huriyah Adani Saoemi

“…Based on that, it is necessary to use an appropriate cryoprotectant to protect the preserved cell. Aims: This study aimed to identify the potential use of date juice concentrate (DJC) as a natural extracellular cryoprotectant to suppress the rate of apoptosis after vitrification. …”
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