Preliminary experimental study on a novel device using biomaterial for shunting fibrotic bleb following Ahmed glaucoma valve surgery in dogs by Songhui Lee, Du-Min Go, Eunji Lee, Dae-Yong Kim, Kangmoon Seo, Seonmi Kang

“…Histological findings indicated that the TBD effectively penetrated the fibrotic membrane surrounding the AGV, with observed mild inflammatory cell infiltration, neovascularization, and myofibroblast differentiation, suggesting filtering bleb formation. …”
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Pathological Characteristics of Primary Bladder Carcinoma Treated at a Tertiary Care Hospital and Changing Demographics of Bladder Cancer in Sri Lanka by S. Sasikumar, K. S. N. Wijayarathna, K. A. M. S. Karunaratne, U. Gobi, A. Pathmeswaran, Anuruddha M. Abeygunasekera

“…It was 5.3% from 1993 to 2000. Pure squamous cell carcinoma was found in 8.1% of patients while primary or de novo carcinoma in situ (not associated with high grade pT1 tumours) was seen in one patient only. …”
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Catalase Biomimetic Sensor Based on Metal by Malikova Nurana Nahmad, Gurbanova Lala Maharram, Ali-Zadeh Nahmad Islam, Nagiev Tofik Murtuza, Shokhzod Ulashov, Kurbanova Shaxnoza

“…The number of different enzymes in a cell is the same as the number of different chemical reactions that occur in it. …”
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Electrosynthesis of ethylene glycol from biomass glycerol by Haoyuan Chi, Zhanpeng Liang, Siyu Kuang, Yaxin Jin, Minglu Li, Tianxiang Yan, Jianlong Lin, Shuangyin Wang, Sheng Zhang, Xinbin Ma

“…We further assemble a zero-gap electrolyzer and demonstrate ethylene glycol electrosynthesis from glycerol to give a decent production rate of 1.32 mmol cm–2 h–1 under a 3.48 V cell voltage. The carbon intensity assessment based on a valid assumption reveals that our strategy may reduce CO2 emissions by over 80 million tons annually compared to conventional fossil fuel routes.…”
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Hypoxia-tropic delivery of nanozymes targeting transferrin receptor 1 for nasopharyngeal carcinoma radiotherapy sensitization by Ruofei Zhang, Yanfang Shen, Xiaoying Zhou, Jianru Li, Hanqing Zhao, Zixia Zhang, Jun Zhao, Hongjun Jin, Shuanshuan Guo, Hui Ding, Guohui Nie, Zhe Zhang, Ying Wang, Xiyun Yan, Kelong Fan

“…In summary, our findings highlight TfR1 as an accessible cell surface target in hypoxic NPC lesions. The nanozyme targeting TfR1 holds promise for enhancing the therapeutic effectiveness of RT in NPC through an in situ oxygen-generation mechanism.…”
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Initial Treatment Modalities in Patients with Newly Diagnosed Primary Lung Cancer in Japan by Qingqing Hu, Kuan-Chih Huang, Ko Nakajo, Yongjing Zhang, Hong Qiu

“…Here, we describe trends in the initial treatment of adults with newly diagnosed primary non-small-cell lung cancer in Japan. This retrospective cohort study used data from JMDC Inc. …”
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Antibacterial and antibiofilm activity of peptide PvGBP2 against pathogenic bacteria that contaminate Auricularia auricular culture bags by Shen Yang, Zijin Yuan, Jude Juventus Aweya, Shanggui Deng, Wuyin Weng, Yueling Zhang, Guangming Liu

“…Transmission electron microscopy (TEM) revealed that PvGBP2 kills bacteria by perforating the cell wall, destroying membrane integrity and resulting in the leakage of intracellular solutes. …”
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Curcumin-Based Nanoparticles: Advancements and Challenges in Tumor Therapy by Hicham Wahnou, Riad El Kebbaj, Bertrand Liagre, Vincent Sol, Youness Limami, Raphaël Emmanuel Duval

“…The mechanisms by which CNPs exert anticancer effects, such as inducing apoptosis, inhibiting cell proliferation, and modulating signaling pathways, are explored in details. …”
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Mendelian randomization analysis reveals genetic evidence for a causal link between inflammatory bowel disease and uterine cervical neoplasms by Chunge Cao, Xiaorui Sun, Xiaohu Chen, Ying Zhang, Chaoyan Yue

“…Patients with IBD and CD require specific attention to prevent cervical squamous cell carcinoma. Further studies to elucidate the underlying mechanisms may reveal new therapeutic targets.…”
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Effects of Replacing Fishmeal with Defatted Black Soldier Fly (Hermetia illucens Linnaeus) Larvae Meal in Japanese Eel (Anguilla japonica) Diet on Growth Performance, Fillet Textur... by I-Pei Kuo, Ching-Shuo Liu, Shuenn-Der Yang, Shih-Hsiang Liang, Yeh-Fang Hu, Fan-Hua Nan

“…Additionally, the intestinal villus length significantly decreased in the R75 group, and the goblet cell densities were significantly lower in the R45, R60, and R75 groups (P<0.05). …”
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Multiple Components of the VHL Tumor Suppressor Complex Are Frequently Affected by DNA Copy Number Loss in Pheochromocytoma by David A. Rowbotham, Katey S. S. Enfield, Victor D. Martinez, Kelsie L. Thu, Emily A. Vucic, Greg L. Stewart, Kevin L. Bennewith, Wan L. Lam

“…Interestingly, we show that VHL-related renal clear cell carcinoma harbored disruption of VHL alone. …”
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Effect of the Carbon Concentration, Blend Concentration, and Renewal Rate in the Growth Kinetic of Chlorella sp. by Adriano Arruda Henrard, Gabriel Martins da Rosa, Luiza Moraes, Michele Greque de Morais, Jorge Alberto Vieira Costa

“…In the semicontinuous cultivation, the microalga is maintained in better concentration of nutrients and the photoinhibition by excessive cell is reduced. Thus, biomass productivity and biocompounds of interest, such as lipid productivity, may be higher than in batch cultivation. …”
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Maternal obesity exacerbates the responsiveness of offspring BALB/c mice to cow’s milk protein-induced food allergy by Jingxin Gao, Tiange Li, Dong Liang, Han Gong, Liang Zhao, Xueying Mao

“…Maternal obesity increased the serum immunoglobulin E and mouse mast cell protease levels, though did not have significant influence on anaphylactic symptom score, core temperature and diarrhea rate of offspring mice after BLG sensitization. …”
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Methylation Status of Vitamin D Receptor Gene Promoter in Benign and Malignant Adrenal Tumors by Catia Pilon, Andrea Rebellato, Riccardo Urbanet, Vincenza Guzzardo, Rocco Cappellesso, Hironobu Sasano, Ambrogio Fassina, Francesco Fallo

“…We previously showed a decreased expression of vitamin D receptor (VDR) mRNA/protein in a small group of adrenocortical carcinoma (ACC) tissues, suggesting the loss of a protective role of VDR against malignant cell growth in this cancer type. Downregulation of VDR gene expression may result from epigenetics events, that is, methylation of cytosine nucleotide of CpG islands in VDR gene promoter. …”
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Autism-Like Behavior and Epigenetic Changes Associated with Autism as Consequences of In Utero Exposure to Environmental Pollutants in a Mouse Model by Denise S. Hill, Robert Cabrera, Deeann Wallis Schultz, Huiping Zhu, Wei Lu, Richard H. Finnell, Bogdan J. Wlodarczyk

“…The Chd7 gene, essential for neural crest cell migration and patterning, was found to be hypomethylated in each experimental animal tested compared to water-treated controls. …”
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Phytomedicine Potential of <i>Oroxylum indicum</i> Root and Its Constituents: Targeting Alzheimer’s Disease by Rattana Summat, Pornthip Waiwut, Supawadee Daodee, Natsajee Nualkaew, Khemjira Phemphunananchai, Puguh Novi Arsito, Yaowared Chulikhit, Orawan Montakantirat, Charinya Khamphukdee, Chantana Boonyarat

“…They inhibited β-amyloid aggregation as measured by the thioflavin T assay and acetylcholinesterase activity using the Ellman method. In cell culture models, <i>O. indicum</i> extract showed an ability to protect neurons from the toxic effects of H₂O₂. …”
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Searching for Biomarkers in Proliferative Diabetic Retinopathy: Amphiregulin and Progranulin by Burak BILGIN, Mete GULER, Hulya CICEK, Selma URFALIOGLU, Gokhan KOKUSARI, Bedia MARANGOZOGLU SAHIN

“…Amphiregulin (AREG) promotes proliferative and regenerative activity and repairs most cell types by binding and activating epidermal growth factor receptors. …”
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Epigenetic Properties of Compounds Contained in Functional Foods Against Cancer by Giulia Casari, Brenda Romaldi, Andrea Scirè, Cristina Minnelli, Daniela Marzioni, Gianna Ferretti, Tatiana Armeni

“…These changes play a critical role in modulating cell function in both healthy and pathological conditions. …”
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A Green Approach to the Production of Hybrid Diindolylmethane-Phenylboronic Acids via a 3MCR: Promising Antineoplasic Molecules by Mónica Zarco Juarez, Joel Omar Martínez, Olivia Noguez Cordova, María Inés Nicolás Vazquez, Teresa Ramírez-Apan, Javier Pérez Flores, René Miranda Ruvalcaba, Gabriel Arturo Arroyo Razo

“…Moreover, the activity of these target molecules was evaluated in the presence of six cancer cell lines (U251 = glia of the central nerve system, PC-3 = prostate, K562 = leukemia, HCT-15 = colon, MCF-7 = breast, and SKLU-1 = lung), which resulted in the meta-regioisomer being the most active. …”
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Progesterone induces meiosis through two obligate co-receptors with PLA2 activity by Nancy Nader, Lama Assaf, Lubna Zarif, Anna Halama, Sharan Yadav, Maya Dib, Nabeel Attarwala, Qiuying Chen, Karsten Suhre, Steven Gross, Khaled Machaca

“…We show using functional assays coupled to unbiased and targeted cell-based lipidomics that ABHD2 possesses a phospholipase A2 (PLA2) activity that requires mPRβ. …”
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