Interference cancelation for high-density fifth-generation relaying network using stochastic geometrical approach by MHD Nour Hindia, Faizan Qamar, Talib Abbas, Kaharudin Dimyati, Mohamad Sofian Abu Talip, Iraj Sadegh Amiri

“…In order to resolve the issue of coverage limitation for the future fifth-generation network, deploying a relay node within a cell is one of the most capable and cost-effective solution, which not only enhances the coverage but also improves the spectral efficiency. …”
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Enhancing early lung cancer detection with MobileNet: A comprehensive transfer learning approach by Raquel Ochoa-Ornelas, Alberto Gudiño-Ochoa, Julio Alberto García-Rodríguez, Sofia Uribe-Toscano

“…This study investigates the application of MobileNetV2, a state-of-the-art, lightweight convolutional neural network, for the accurate classification of lung adenocarcinoma (LAC), benign lung tissue (BLT), and lung squamous cell carcinoma (LUSC). To enhance the model’s generalization capabilities, we augmented the widely used LC25000 dataset with additional histopathological images sourced from the National Cancer Institute. …”
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Metformin Inhibits Mouse Islet Insulin Secretion and Alters Intracellular Calcium in a Concentration-Dependent and Duration-Dependent Manner near the Circulating Range by Lindor Gelin, Jiewen Li, Kathryn L. Corbin, Ishrat Jahan, Craig S. Nunemaker

“…With 1 mM metformin, islets showed severe impairments in calcium handling, inhibition of insulin secretion, and increased cell death. No stimulatory effects of metformin were observed for any experimental endpoint. …”
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Dexmedetomidine Inhibits Voltage-Gated Sodium Channels via α2-Adrenoceptors in Trigeminal Ganglion Neurons by Sang-Taek Im, Youn Yi Jo, Gayoung Han, Hyun Jung Jo, Yong Ho Kim, Chul-Kyu Park

“…Two types of voltage-gated sodium channels, Nav1.7 and Nav1.8, as well as α2-adrenoceptors are expressed in primary sensory neurons of the trigeminal ganglion (TG). Using whole-cell patch-clamp recordings, we investigated the effects of dexmedetomidine on voltage-gated sodium channel currents (INa) via α2-adrenoceptors in dissociated, small-sized TG neurons. …”
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Icaritin Provokes Serum Thrombopoietin and Downregulates Thrombopoietin/MPL of the Bone Marrow in a Mouse Model of Immune Thrombocytopenia by Ke Zhang, Zhenfeng Dai, Runzhe Liu, Fang Tian, Xi Liu, Yi Sun, Xin Zhao, Xiaoping Pu

“…Icaritin promotes platelet production and regulates T cell polarization, but its mechanism is not clear. …”
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Thyme Essential Oil as a Potential Tool Against Common and Re-Emerging Foodborne Pathogens: Biocidal Effect on Bacterial Membrane Permeability by Martina Di Rosario, Leonardo Continisio, Giuseppe Mantova, Francesca Carraturo, Elena Scaglione, Daniela Sateriale, Giuseppina Forgione, Chiara Pagliuca, Caterina Pagliarulo, Roberta Colicchio, Mariateresa Vitiello, Paola Salvatore

“…Additionally, Thy-EO exerted rapid bactericidal kinetics characterized by the disruption of bacterial cell membrane integrity over time. Results highlight Thy-EO’s potential as an alternative antimicrobial agent, demonstrating that treatment with Thy-EO significantly and irreversibly affects the growth of the tested foodborne pathogens.…”
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Clinical Manifest X-Linked Recessive Adrenoleukodystrophy in a Female by Gyda Hlin Skuladottir Jack, Karolina Malm-Willadsen, Anja Frederiksen, Dorte Glintborg, Marianne Andersen

“…The intracellular accumulation of VLCFA leads to demyelination in the central nervous system (CNS) and cell destruction in the adrenal glands. ALD primarily affects males; however, females may develop milder symptoms that may be difficult to recognize. …”
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Robotic Partial Nephrectomy with the Da Vinci Xi by George J. S. Kallingal, Sanjaya Swain, Fadi Darwiche, Sanoj Punnen, Murugesan Manoharan, Mark L. Gonzalgo, Dipen J. Parekh

“…Mean ischemia time was 17.5 minutes and estimated blood loss was 120 mLs. 12 of 15 patients had renal cell carcinoma. Two patients had oncocytoma and one had benign cystic disease. …”
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GB18-06, a nanobody targeting GDF15, effectively alleviates weight loss and restores physical function in cachexia models by Yu Huang, Jinyong Wang, Xiling Wei, Hui Zhang, Wei Shang, Xiangling Zhang, Lanjiao Zhai, Xi Chen, Huiming Li, Suofu Qin

“…Growth differentiation factor 15 (GDF15) can suppress appetite and regulate energy balance through binding to glial cell-derived neurotrophic factor receptor alpha-like (GFRAL). …”
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Variation of the Side Chain Branch Position Leads to Vastly Improved Molecular Weight and OPV Performance in 4,8-dialkoxybenzo[1,2-b:4,5-b′]dithiophene/2,1,3-benzothiadiazole Copol... by Robert C. Coffin, Christopher M. MacNeill, Eric D. Peterson, Jeremy W. Ward, Jack W. Owen, Claire A. McLellan, Gregory M. Smith, Ronald E. Noftle, Oana D. Jurchescu, David L. Carroll

“…The hole mobility as determined by thin film transistor (TFT) measurements is improved from ~1×10−6 cm2/Vs for P1 and P2 to 7×10−4 cm2/Vs for P3, while solar cell power conversion efficiency in increased to 2.91% for P3 relative to 0.31% and 0.19% for P1 and P2, respectively.…”
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Puerarin Suppress Apoptosis of Human Osteoblasts via ERK Signaling Pathway by Ling-juan Liu, Li-qun Liu, Tao Bo, Shi-jun Li, Zhen Zhu, Rong-rong Cui, Ding-an Mao

“…In this study, we detected the function of puerarin on serum-free-induced cell apoptosis using ELISA and TUNEL arrays and then found that the mortality of hOBs was significantly decreased after exposure to 10−10–10−6 M puerarin and reached the maximal antiapoptotic effect at the concentration of 10−8 M. …”
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Piperine Alleviates Doxorubicin-Induced Cardiotoxicity via Activating PPAR-γ in Mice by Jie Yan, Si-Chi Xu, Chun-Yan Kong, Xiao-Yang Zhou, Zhou-Yan Bian, Ling Yan, Qi-Zhu Tang

“…Piperine also improved cell viability, and reduced oxidative damage and inflammatory factors in cardiomyocytes. …”
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Drug Repositioning for Gynecologic Tumors: A New Therapeutic Strategy for Cancer by Kouji Banno, Miho Iida, Megumi Yanokura, Haruko Irie, Kenta Masuda, Yusuke Kobayashi, Eiichiro Tominaga, Daisuke Aoki

“…For example, PPAR ligands may be effective against ovarian cancer, since PPAR activation eliminates COX-2 expression, arrests the cell cycle, and induces apoptosis. Metformin, an antidiabetic drug, is effective for endometrial cancer through inhibition of the PI3K-Akt-mTOR pathway by activating LKB1-AMPK and reduction of insulin and insulin-like growth factor-1 due to AMPK activation. …”
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Polypeptide Globular Adiponectin Ameliorates Hypoxia/Reoxygenation-Induced Cardiomyocyte Injury by Inhibiting Both Apoptosis and Necroptosis by Kaiyi Zhu, Jia Guo, Xiaoxue Yu, Que Wang, Chao Yan, Quan Qiu, Weiqing Tang, Xiuqing Huang, Hongna Mu, Lin Dou, Yunfei Bian, Qinghua Han, Tao Shen, Jian Li, Chuanshi Xiao

“…We found that globular adiponectin treatment attenuated cardiomyocyte injury as indicated by increased cell viability and reduced lactate dehydrogenase release following hypoxia/reoxygenation. …”
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Lipid metabolic reprogramming and associated ferroptosis in osteosarcoma: From molecular mechanisms to potential targets by Zhiyang Yin, Guanlu Shen, Minjie Fan, Pengfei Zheng

“…Ferroptosis is an iron-dependent form of programmed cell death associated with lipid peroxidation. This review provides an in-depth analysis of the complex relationship between lipid metabolic reprogramming and associated ferroptosis in OS from the perspective of metabolic enzymes and metabolites. …”
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Pretreatment of Small-for-Size Grafts In Vivo by γ-Aminobutyric Acid Receptor Regulation against Oxidative Stress-Induced Injury in Rat Split Orthotopic Liver Transplantation by Tomohide Hori, Shinji Uemoto, Lindsay B. Walden, Feng Chen, Ann-Marie T. Baine, Toshiyuki Hata, Justin H. Nguyen

“…GABAR regulation appeared to reduce DNA damage via the ATM/H2AX pathway and to promote cell survival via the PI3K/Akt pathway. Conclusions. …”
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Brain-Specific SNAP-25 Deletion Leads to Elevated Extracellular Glutamate Level and Schizophrenia-Like Behavior in Mice by Hua Yang, Mengjie Zhang, Jiahao Shi, Yunhe Zhou, Zhipeng Wan, Yicheng Wang, Yinghan Wan, Jun Li, Zhugang Wang, Jian Fei

“…Compared with Ctrls, SNAP-25 was dramatically reduced by about 60% both in cytoplasm and in membrane fractions of cerebral cortex of cKOs, while the other two core members of SNARE complex: Syntaxin-1 (increased ~80%) and Vamp2 (increased ~96%) were significantly increased in cell membrane part. Riluzole, a glutamate release inhibitor, significantly attenuated the locomotor hyperactivity deficits in cKO mice. …”
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<i>Cordyceps militaris</i>-Derived Bioactive Gels: Therapeutic and Anti-Aging Applications in Dermatology by Trung Quang Nguyen, Thinh Van Pham, Yusuf Andriana, Minh Ngoc Truong

“…These compounds exhibit multiple bioactivities, including apoptosis induction, cell cycle arrest, and anti-inflammatory effects, which have been shown to be particularly effective against melanoma and other skin cancers. …”
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Prevalence of Malaria and TB Coinfection at a National Tuberculosis Treatment Centre in Uganda by Joseph Baruch Baluku, Sylvia Nassozi, Brian Gyagenda, Margret Namanda, Irene Andia-Biraro, William Worodria, Pauline Byakika-Kibwika

“…Blood samples were tested for malaria blood smear, rapid malaria diagnostic test (RDT), complete blood count, haematological film analysis, HIV serology, and CD4+ and CD8+ cell counts. Malaria was defined as either a positive blood smear or RDT. …”
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Determination of Polyphenol Components of Korean Prostrate Spurge (Euphorbia supina) by Using Liquid Chromatography—Tandem Mass Spectrometry: Overall Contribution to Antioxidant Ac... by Yi Song, Sung Woo Jeong, Won Sup Lee, Semin Park, Yun-Hi Kim, Gon-Sup Kim, Soo Jung Lee, Jong Sung Jin, Chi-Yeon Kim, Ji Eun Lee, Se Yun Ok, Ki-Min Bark, Sung Chul Shin

“…The antioxidant activities of the flavonoids were evaluated in terms of 1,1-diphenyl-2-picrylhydrazyl and 2,2′-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) radical cation-scavenging activity, and the reducing power showed a dose-dependent increase. Cell viability was effectively suppressed at polyphenol mixture concentrations >250 mg/L.…”
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