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21621
Aspects of improving metrological characteristics of a sensor based on palladium nanoparticles for methionine determination
Published 2025-01-01“…All the synthesized nanoparticles have a cubic face-centered crystal cell. The composition of the micelles depends on the reducing properties of the reagents used. …”
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21622
Association between Circulating Ectodysplasin A and Diabetic Kidney Disease
Published 2023-01-01“…Insulin resistance and pancreatic cell function were assessed by HOMA. Results. Circulating EDA concentration was significantly increased in T2DM patients and increased with the degree of albuminuria. …”
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21623
Potential of Peroxisome Proliferator-Activated Receptor Gamma Antagonist Compounds as Therapeutic Agents for a Wide Range of Cancer Types
Published 2008-01-01“…In addition, PPARγ antagonists, such as T0070907 and GW9662, have exhibited antiproliferative effects on a broad range of hematopoietic and epithelial cell lines, usually with greater potency than agonists. …”
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21624
Halodule uninervis extract facilitates the green synthesis of gold nanoparticles with anticancer activity
Published 2025-02-01“…The produced AuNPs exhibited anticancer activity against several human cancer cell lines, highlighting their potential efficacy as anticancer therapeutic agents. …”
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21625
Evaluating the Factors Affecting COVID-19 Patients’ Mortality in Arak in 2020
Published 2022-01-01“…There was a significant relationship in terms of blood pressure, age, oxygen saturation, tachycardia, tachypnea, the interval between the onset of symptoms and hospitalization, diabetes mellitus, lung disease, cardiovascular disease, history of opium abuse, C-reactive protein, white blood cell, lymphocytes, hemoglobin, creatinine elevation, elevated liver enzyme, creatine phosphokinase, lactate dehydrogenase, ferritin, D-dimer, troponin, prothrombin time, international normalized ratio, intensive care unit admission days, arrhythmia, sepsis, acute respiratory distress syndrome, acute kidney injury (AKI), and the type of antiviral and antibiotic therapy between the two groups of patients. …”
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21626
Safety and effectiveness of an herbal decoction (modified Saengmaeksan) in hypertensive patients: Protocol for a real-world prospective observational study.
Published 2025-01-01“…<h4>Discussion</h4>Modified Saengmaeksan has shown potential for lowering blood pressure in clinical settings, supported by animal and cell studies. However, human studies are scarce. …”
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21627
Socio-demographic disparities in global trends of lip and oral cavity neoplasms from 1990 to 2021
Published 2025-02-01“…Abstract Oral cancer, the 13th most common globally, is primarily squamous cell carcinoma linked to tobacco, alcohol, and HPV. …”
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21628
Structure-guided identification of mitogen-activated protein kinase-1 inhibitors towards anticancer therapeutics.
Published 2025-01-01“…This pathway plays a crucial role in various cellular processes, including cell proliferation, differentiation, adhesion, migration, and survival. …”
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21629
Canonization of graphs during transistor circuits decompilation
Published 2022-09-01“…The proposed methods are implemented in C++ as a part of a transistor circuit decompilation program for the case without predetermined cell library. The proposed method of canonization of labeled graphs is used: to recognize topologically equivalent subcircuits among functionally equivalent subcircuits that implement logical elements; to split the set of subcircuits not recognized as logical elements into classes of topologically equivalent ones; to verify the results of extraction of the hierarchical circuit at the transistor-logic level relative to the flat circuit at the transistor level.Conclusion. …”
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21630
A plant-derived biostimulant Aminolom Enzimatico® application stimulates chlorophyll content, electrolyte leakage, stomata density and root yield of radishes under salinity stress
Published 2025-01-01“…Therefore, the study aimed to determine how applying a foliar plant-derived biostimulant (Aminolom Enzimatico® 24%) affects the growth (leaf area, biomass weight, root diameter, root fresh weight, and water-soluble dry matter), physiology (chlorophyll content, electrolyte leakage, cell membrane stability, and relative water content), and stomata of the lower and upper parts of leaves in radish plants (Raphanus sativus L.) under salinity stress. …”
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21631
Current understanding of antimicrobial resistance mechanisms in bacteria (analytical review)
Published 2022-03-01“…Mechanisms of acquired resistance are described: antibiotic modification or degradation; active removal of an antimicrobial from a bacterial cell – efflux (draining out); sequestration; target modification (bypass). …”
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21632
Comparative Genome Characterization of a Petroleum-Degrading Bacillus subtilis Strain DM2
Published 2019-01-01“…Comparative analysis showed that the genome of strain DM2 encodes some strain-specific proteins in comparison with B. subtilis subsp. subtilis str. 168, such as carboxymuconolactone decarboxylase family protein, gfo/Idh/MocA family oxidoreductases, GlsB/YeaQ/YmgE family stress response membrane protein, HlyC/CorC family transporters, LLM class flavin-dependent oxidoreductase, and LPXTG cell wall anchor domain-containing protein. Most of the common strain-specific proteins in DM2 and MJ01 strains, or proteins unique to DM2 strain, are involved in the pathways related to stress response, signaling, and hydrocarbon degradation. …”
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21633
Effect of Allicin and Artesunate Combination Treatment on Experimental Mice Infected with Plasmodium berghei
Published 2022-01-01“…For combination, allicin and ART showed a synergistic effect at the combination doses of ED50, ED50 1/2, and ED50 1/4 with significantly (p<0.01) prevented reduction of packed cell volume, bodyweight loss, rapid dropping of rectal temperature, and markedly prolonged mean survival time, compared with the untreated control and single treatment. …”
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21634
Homology Modeling and Expression of Recombinant NS5-RdRp Based on the Indonesian Local Strain of Dengue Virus for Anti-Dengue Drug Development
Published 2024-09-01“…The isolated NS5-RdRp gene from the local strain was then inserted into the pET28a(+) plasmid and transformed into E. coli BL21(DE3) as the host cell. Recombinant NS5-RdRp was predominantly found in the insoluble fraction with a molecular weight of 72 kDa. …”
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21635
Head and Neck Schwannomas: A Surgical Challenge—A Series of 5 Cases
Published 2018-01-01“…They originate from any nerve covered with schwann cell sheath. Schwannomas constitute 25–45% of tumors of the head and neck. …”
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21636
No Contribution of GAD-65 and IA-2 Autoantibodies around Time of Diagnosis to the Increasing Incidence of Juvenile Type 1 Diabetes: A 9-Year Nationwide Danish Study
Published 2016-01-01“…Our key objective was to examine whether increased levels of autoantibodies against the β-cell autoantigens glutamic acid decarboxylase (isoform 65) (GADA) and insulinoma associated antigen-2A (IA-2A) mirrored the 3.4% annual increase in incidence of T1D. …”
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21637
The Natural History and Predictors for Intervention in Patients with Small Renal Mass Undergoing Active Surveillance
Published 2015-01-01“…Eight of the 54 (15%) masses which grew in size underwent a nephron-sparing surgery, of which two were oncocytomas and six were renal cell carcinoma. Growth rate and mass diameter on diagnosis were significantly greater in the group of patients who underwent a surgery. …”
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21638
Hepatitis in Disseminated Bacillus Calmette-Guérin Infection
Published 2000-01-01“…Local immunotherapy with an attenuated live strain of Mycobacterium bovis, bacillus Calmette-Guérin (BCG), is an effective and frequently used treatment for in situ transitional cell carcinoma (TCC) of the bladder. Success rates are high, and serious side effects are infrequent but can affect every organ system. …”
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21639
Targeting ferroptosis in prostate cancer management: molecular mechanisms, multidisciplinary strategies and translational perspectives
Published 2025-02-01“…Ferroptosis is a new form of regulatory cell death caused by iron-dependent lipid peroxidation, which has a dual role in PCa evolution and treatment due to the multi-omics cascade of interactions among pathways and environmental stimuli. …”
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21640
Integrative genetics and multiomics analysis reveal mechanisms and therapeutic targets in vitiligo highlighting JAK STAT pathway regulation of CTSS
Published 2025-01-01“…Microarray and single-cell RNA-seq data showed differential expression of CTSS and STAT1/3 in vitiligo patients’ blood and skin lesions. …”
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