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21541
Uncovering the genetic basis of milk production traits in Mexican Holstein cattle based on individual markers and genomic windows.
Published 2025-01-01“…The objective of this study was to evaluate the proportion of genetic variance explained by single nucleotide polymorphism markers, individually or clustered in 1, 2, and 5 Mb windows, for milk yield, fat yield, protein yield, fat content, protein content, and somatic cell score in Mexican Holstein cattle. The analysis included data from 640,746 lactation records of 358,857 cows born between 1979 and 2019, distributed in 353 herds in 18 states of Mexico. …”
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21542
Modeling of autowave processes in active media with inhomogeneous properties
Published 2023-11-01“…As one of the factors creating heterogeneity of the active distributed environment, the change in the decay coefficient of the activator in its volume is also considered. In this case, each cell of the model is assigned a random value of the specified coefficient, lying in a given interval from the minimum to the maximum value. …”
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21543
Molecular Markers in Upper Urothelial Carcinoma Associated to Balkan Endemic Nephropathy. Aristolochic Acid as the Major Risk Factor of the Worldwide Disease
Published 2009-01-01“…This investigation identifies the p53 pathway as the specific cell cycle marker involved in BEN-associated UUC.…”
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21544
Aquaporin-1-Mediated Effects of Low Level He-Ne Laser Irradiation on Human Erythrocytes
Published 2012-01-01“…Comprehensive morphological parameters of an intact cell such as contact area, perimeter, roundness and erythrocyte elongation index (EEI) were measured to characterize erythrocyte deformability with fast micro multi-channel spectrophotometer. …”
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21545
Development of a broad-spectrum epitope-based vaccine against Streptococcus pneumoniae.
Published 2025-01-01“…Two potential vaccine candidates, CbpA and PspA, were identified, and their B-cell, CTL, and HTL epitopes were predicted and connected with suitable linkers, adjivant and PADRE sequence. …”
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21546
HHV-8-Associated Lymphoproliferative Disorders and Pathogenesis in an HIV-Positive Patient
Published 2019-01-01“…The World Health Organization has recently updated the classification of HHV-8-associated LPDs by introducing HHV-8-positive germinotropic LPD (GLPD) in addition to the previously recognized entities of HHV-8-positive diffuse large B-cell lymphoma, not otherwise specified (DLBCL, NOS), primary effusion lymphoma (PEL), and HHV-8-positive multicentric Castleman’s disease (MCD). …”
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21547
Potency of Garlic Extract Against Koi Herpesvirus (KHV) in Common Carp
Published 2007-07-01“…Hemoglobin concentration, red and white blood cell numbers, and leukocyte number were counted. …”
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21548
Evidence on the Heroin-Mediated Impairment of the Oxidative Status of Erythrocytes
Published 2022-01-01“…Hematological analysis revealed that addicts had a significantly higher red cell distribution width, consistent with the mild anisocytosis and poikilocytosis of erythrocytes. …”
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21549
Consensus guidelines for the management of treatment-naïve chronic lymphocytic leukaemia in Singapore (2024)
Published 2025-01-01“…Due to the superior efficacy of targeted agents (Bruton's tyrosine kinase inhibitors [BTKis] and B-cell lymphoma 2 inhibitors [BCL2is]), sthese are favoured over standard chemotherapy or chemotherapy-immunotherapy, especially for patients with del(17p) or TP53 mutation, and less fit patients. …”
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21550
Transcriptomics profiling of Parkinson’s disease progression subtypes reveals distinctive patterns of gene expression
Published 2025-09-01“…All three subtypes showed a significant modulation of pathways related to the regulation of gene expression, metabolism, and cell signaling. ML revealed that the progression subtype with the worst prognosis can be predicted at baseline with 0.877 AUROC, yet the contribution of gene expression was marginal for the prediction of the subtypes. …”
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21551
The status of when- and where- clauses without an overt antecedent
Published 2009-01-01“…L’existence de tels exemples rend nécessaire de postuler une zone de chevauchement entre la catégorie des interrogatives et celle des relatives libres. Lorsqu’il s’agit de déterminer à quel type de subordonnée on a affaire, il est également essentiel de se demander si cette dernière peut remplir la fonction de complément circonstanciel, en gardant en mémoire le fait que certains circonstants jouent le rôle de repère énonciatif pour l’ensemble d’un énoncé donné. …”
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21552
Modified Gegen Qinlian Decoction Ameliorates DSS-Induced Ulcerative Colitis in Mice by Inhibiting Ferroptosis via Nrf2/GPX4 Pathway
Published 2024-01-01“…Ferroptosis, a form of programmed cell death, is considered a novel target for the treatment of ulcerative colitis (UC). …”
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21553
Design, Synthesis, and Biological Evaluation of Triazolyl- and Triazinyl-Quinazolinediones as Potential Antitumor Agents
Published 2019-01-01“…The antitumor activity of the synthesized compounds was evaluated against two human cell lines: human colon carcinoma HCT116 and human hepatocellular carcinoma HEP-G2. …”
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21554
A Rare Case of Immunotactoid Glomerulopathy Associated with Hodgkin Lymphoma
Published 2021-01-01“…In hematologic malignancies, multiple myeloma and other mature B-cell malignancies are the most common hematologic malignancies, and Hodgkin lymphoma (HL) is extremely rare. …”
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21555
Soft Sensor Modeling Method Based on SPA-GWO-SVR for Marine Protease Fermentation Process
Published 2021-01-01“…Some key variables (such as cell concentration, substrate concentration, and enzyme activity) that directly reflect the fermentation process's quality are difficult to measure in real-time by traditional measurement methods. …”
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21556
The Systematic Analysis of Exercise Mechanism in Human Diseases
Published 2022-01-01“…Then, GSEA analysis revealed that glycosaminoglycan biosynthesis chondroitin sulfate, type II diabetes mellitus, and basal cell carcinoma were related with exercise samples. …”
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21557
Relationship between the ultrasound features of different molecular subtypes of breast cancer and positive PD-1/PD-L1 expression
Published 2025-02-01“…Objectives To analyze differences in programmed cell death protein 1/ligand 1 (PD-1/PD-L1) expression, as well as the relationships between ultrasound/contrast-enhanced ultrasound characteristics and PD-1/PD-L1 expression, among invasive breast cancer molecular subtypes. …”
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21558
Epithelial to Mesenchymal Transition Relevant Subtypes with Distinct Prognosis and Responses to Chemo- or Immunotherapies in Osteosarcoma
Published 2022-01-01“…Immunological features were evaluated through immune cell infiltration, immune checkpoint expression, and activity of cancer immunity cycle. …”
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21559
Electrochemical synthesis and characterization of BaB6 from molten melt
Published 2009-01-01“…DTA/TGA studies were made to determine the eutectic point of the melt and it was found to be around 821oC. The electrolytic cell had a high purity graphite crucible, which served as the electrolyte holding vessel and also as the anode for the electrolysis. …”
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21560
Vanadate reduction by gram-positive fermentative bacteria isolated from deep-sea sediments on the northern Central Indian Ridge.
Published 2025-01-01“…The specific rate of vanadate removal by VROV1 was as high as 2.8 pmol/cell/day, which is comparable to that of metal-reducing bacteria and markedly exceeds that of L. raffinolactis. …”
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