Synthesis and Biological Evaluation of 2-Hydroxy-3-[(2-aryloxyethyl)amino]propyl 4-[(Alkoxycarbonyl)amino]benzoates by Jan Tengler, Iva Kapustíková, Matúš Peško, Rodney Govender, Stanislava Keltošová, Petr Mokrý, Peter Kollár, Jim O'Mahony, Aidan Coffey, Katarína Král'ová, Josef Jampílek

“…Cytotoxicity assay of effective compounds was performed using the human monocytic leukaemia THP-1 cell line. Compounds with predicted amphiphilic properties were also tested for their effects on the rate of photosynthetic electron transport (PET) in spinach (Spinacia oleracea L.) chloroplasts. …”
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The influence of respiratory infections on Henoch-Schönlein purpura in children by Bili Wang, Wenqing Xiang, Zhouyue Zhu, Hongqiang Shen

“…Results Compared with the control group, children with HSP exhibited a significant increase in urine red blood cell count, urine microalbuminuria, and urine protein/creatinine ratio (P < 0.001). …”
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Conditional KCa3.1-transgene induction in murine skin produces pruritic eczematous dermatitis with severe epidermal hyperplasia and hyperkeratosis. by Javier Lozano-Gerona, Aida Oliván-Viguera, Pablo Delgado-Wicke, Vikrant Singh, Brandon M Brown, Elena Tapia-Casellas, Esther Pueyo, Marta Sofía Valero, Ángel-Luis Garcia-Otín, Pilar Giraldo, Edgar Abarca-Lachen, Joaquín C Surra, Jesús Osada, Kirk L Hamilton, Siba P Raychaudhuri, Miguel Marigil, Ángeles Juarranz, Heike Wulff, Hiroto Miura, Yolanda Gilaberte, Ralf Köhler

“…Here, we explored the consequences of genetically encoded induction of the cell volume-regulating Ca2+-activated KCa3.1 channel (Kcnn4) for murine epidermal homeostasis. …”
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Low‐carbon scheduling model of multi‐virtual power plants based on cooperative game considering failure risks by Chen Wu, Zhinong Wei, Yang Cao, Yiteng Xu, Tiantian Wei, Haiteng Han, Sheng Chen, Haixiang Zang

“…VPP also contains a variety of flexible resources such as demand response (DR), energy storage (ES), and fuel cell (FC). How to achieve efficient energy utilization while reducing carbon emissions and resisting the risk of failure caused by extreme weather has attracted widespread attention. …”
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Incidence and Evaluation of Incidental Abnormal Bone Marrow Signal on Magnetic Resonance Imaging by Gunjan L. Shah, Aaron S. Rosenberg, Jamie Jarboe, Andreas Klein, Furha Cossor

“…With median follow-up of 41 months, 6% of patients were diagnosed with malignancies including multiple myeloma, non-Hodgkins lymphoma, metastatic non-small cell lung cancer, and metastatic adenocarcinoma. …”
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Cannabidiol Rescues Acute Hepatic Toxicity and Seizure Induced by Cocaine by Luciano Rezende Vilela, Lindisley Ferreira Gomides, Bruna Araújo David, Maísa Mota Antunes, Ariane Barros Diniz, Fabrício de Araújo Moreira, Gustavo Batista Menezes

“…Considering the protective role of the endocannabinoid system against cell toxicity, we hypothesized that treatment with an anandamide hydrolysis inhibitor, URB597, or with a phytocannabinoid, cannabidiol (CBD), protects against cocaine toxicity. …”
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SIAE Rare Variants in Juvenile Idiopathic Arthritis and Primary Antibody Deficiencies by Eirini Sevdali, Elena Tsitsami, Maria Tsinti, Evangelia Farmaki, Efimia Papadopoulou-Alataki, Anastasios E. Germenis, Matthaios Speletas

“…Sialic acid acetylesterase (SIAE) deficiency was suggested to lower the levels of ligands for sialic acid-binding immunoglobulin-like receptors, decreasing the threshold for B-cell activation. In humans, studies of rare heterozygous loss-of-function mutations in SIAE gene in common autoimmune diseases, including juvenile idiopathic arthritis (JIA), yielded inconsistent results. …”
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Impaired Healing of a Cutaneous Wound in an Inducible Nitric Oxide Synthase-Knockout Mouse by Takashi Kitano, Hiroshi Yamada, Maki Kida, Yuka Okada, Shizuya Saika, Munehito Yoshida

“…Population of granulation tissue-related cell types, that is, myofibroblasts and macrophages, growth factor expression, and reepithelialization were evaluated. …”
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Mechanisms and Consequences of Dopamine Depletion-Induced Attenuation of the Spinophilin/Neurofilament Medium Interaction by Andrew C. Hiday, Michael C. Edler, Asma B. Salek, Cameron W. Morris, Morrent Thang, Tyler J. Rentz, Kristie L. Rose, Lisa M. Jones, Anthony J. Baucum

“…Specifically, there was a decrease in the association of spinophilin with neurofilament medium (NF-M) in dopamine-depleted striatum. Using a heterologous cell line, we determined that spinophilin binding to NF-M required overexpression of the catalytic subunit of protein kinase A and was decreased by cyclin-dependent protein kinase 5. …”
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Predicting the Onset of Cavitation in Automotive Torque Converters—Part I: Designs with Geometric Similitude by D. L. Robinette, J. M. Schweitzer, D. G. Maddock, C. L. Anderson, J. R. Blough, M. A. Johnson

“…Torque converter operating thresholds for cavitation were determined experimentally with a dynamometer test cell at the stall operating condition using nearfield acoustical measurements. …”
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Multiomics-based assessment of the impact of airflow on diverse plant callus cultures by June-Sik Kim, Muneo Sato, Mikiko Kojima, Muchamad Imam Asrori, Yukiko Uehara-Yamaguchi, Yumiko Takebayashi, Thi Nhung Do, Thi Yen Do, Kieu Oanh Nguyen Thi, Hitoshi Sakakibara, Keiichi Mochida, Shinjiro Ogita, Masami Yokota Hirai

“…Abstract Plant cell culture has multiple applications in biotechnology and horticulture, from plant propagation to the production of high-value biomolecules. …”
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Thermo-mechanical and micro-structural properties of xylanase containing whole wheat bread by G. Ghoshal, U.S. Shivhare, U.C. Banerjee

“…Hemicelluloses are main components of cell walls of cereal grains. Moreover, hemicelluloses are considered as potential sources of mono- and oligosaccharides. …”
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A Lifelong Smoker with Hypopituitarism: Rethinking the Hypothesis of a Tumor in the Hypophysis by Nestoras Mathioudakis, Alfredo Quinones-Hinojosa, Roberto Salvatori, Shehzad Basaria

“…Transsphenoidal resection of the tumor was performed and histopathology revealed small cell carcinoma. The patient received chemotherapy, but died 18 months later due to widespread brain metastases. …”
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Remission Achieved in Refractory Advanced Takayasu Arteritis Using Rituximab by D. Ernst, M. Greer, M. Stoll, D. Meyer-Olson, R. E. Schmidt, T. Witte

“…Given evidence of refractory disease activity on maximal standard therapy, we initiated rituximab, based on recently reported B-cell activity in TA.…”
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Gastric Glomus Tumor: A Rare Cause of Upper Gastrointestinal Bleeding by Yoshinori Handa, Mikihiro Kano, Mayumi Kaneko, Naoki Hirabayashi

“…Because analysis of the possible medical causes remained inconclusive and the risk of rebleeding, laparoscopy-assisted gastric wedge resection was performed after administration of 10 units of red cell concentrate. Histological and immunohistological analysis revealed the tumor to be a gastric glomus tumor. …”
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Oligodendrocyte Injury in Multiple Sclerosis. by Mateo Përgjegji, Klei Bame, Ketrina Ceka, Jera Cenalia , Sibora Bërdica , Teona Bushati

“…Emerging therapeutic strategies, such as targeting metabolic pathways, reducing oxidative stress, and enhancing autophagy, have demonstrated potential in preclinical studies. Furthermore, stem cell therapies are being explored for their ability to regenerate oligodendrocytes and restore myelin integrity. …”
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in vitro evaluation of the efficiency of Artemisia judaica leaf extract on sporulation of Eimeria papillate oocysts and its cytotoxicity by M.A. Esam, N.M. Saleh, A.G. Rewaida, A.Q.H. Waleed, A. Afaf, A.A. Sarah, Al-Q. Saleh

“…Our results revealed that A. judaica has cytotoxic activity against breast and lung cancer cell line with a promising IC50 of 480.3 and 359.2µg/mL, respectively compared to doxorubicin as a standard.…”
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Mitochondrial Fusion Proteins and Human Diseases by Michela Ranieri, Simona Brajkovic, Giulietta Riboldi, Dario Ronchi, Federica Rizzo, Nereo Bresolin, Stefania Corti, Giacomo P. Comi

“…Mitochondria are highly dynamic, complex organelles that continuously alter their shape, ranging between two opposite processes, fission and fusion, in response to several stimuli and the metabolic demands of the cell. Alterations in mitochondrial dynamics due to mutations in proteins involved in the fusion-fission machinery represent an important pathogenic mechanism of human diseases. …”
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The anti-oxidation related bioactive materials for intervertebral disc degeneration regeneration and repair by Yingjie Mai, Siying Wu, Penghui Zhang, Ningning Chen, Jun Wu, Fuxin Wei

“…Consequently, oxidative stress contributes to the degradation of the extracellular matrix (ECM), promotes cell apoptosis, and exacerbates disc tissue damage. …”
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Intranasally administrated fusion-inhibitory lipopeptides block SARS-CoV-2 infection in mice and enable long-term protective immunity by Said Mougari, Valérie Favède, Camilla Predella, Olivier Reynard, Stephanie Durand, Magalie Mazelier, Edoardo Pizzioli, Didier Decimo, Francesca T. Bovier, Lauren M. Lapsley, Candace Castagna, Nicole A. P. Lieberman, Guillaume Noel, Cyrille Mathieu, Bernard Malissen, Thomas Briese, Alexander L. Greninger, Christopher A. Alabi, N. Valerio Dorrello, Stéphane Marot, Anne-Geneviève Marcelin, Ana Zarubica, Anne Moscona, Matteo Porotto, Branka Horvat

“…The lipopeptides block SARS-CoV-2 infection in cell lines and lung-derived organotypic cultures. …”
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