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21341
The infectivity of virus particles from Wolbachia-infected Drosophila
Published 2025-01-01“…Whilst the mechanisms behind Wolbachia-mediated viral blocking are not fully characterised, it was recently shown that viruses grown in the presence of Wolbachia in some Dipteran cell cultures are less infectious than those grown in the absence of Wolbachia. …”
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21342
Conversion of Low-Flow Priapism to High-Flow State Using T-Shunt with Tunneling
Published 2017-01-01“…Case 1 was a 33-year-old male with sickle cell anemia and case 2 was a 24-year-old male with idiopathic thrombocytopenic purpura. …”
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21343
Heavy Metal Stress and Some Mechanisms of Plant Defense Response
Published 2015-01-01“…AM can effectively immobilize HMs and reduce their uptake by host plants via binding metal ions to hyphal cell wall and excreting several extracellular biomolecules. …”
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21344
Phenoxybenzamine in Complex Regional Pain Syndrome: Potential Role and Novel Mechanisms
Published 2013-01-01“…Also, a recent study identified phenoxybenzamine as a potential intervention for pain mediation from its effects on gene expression in human cell lines; on this basis, it was tested and found to be capable of reducing pain behavior in a classical animal model of chronic pain.…”
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21345
Febuxostat Improves Uric Acid Levels and Renal Function in Patients with Chronic Kidney Disease and Hyperuricemia: A Meta-Analysis
Published 2022-01-01“…Uric acid nephropathy, also known as hyperuricemia nephropathy or gouty nephropathy, is characterized by uric acid crystal deposition and inflammatory cell infiltration. Herein, we aimed to demonstrate the role of febuxostat on uric acid levels and renal function in patients with chronic kidney disease and hyperuricemia. …”
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21346
Cryo-EM structure of Sudan ebolavirus glycoprotein complexed with its human endosomal receptor NPC1
Published 2025-02-01“…These findings advance our understanding of ebolavirus cell entry, tissue tropism, and host range.…”
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21347
ACE2 : S1 RBD Interaction-Targeted Peptides and Small Molecules as Potential COVID-19 Therapeutics
Published 2021-01-01“…SARS-CoV-2 initiates invasion of the human target cell through direct contact between the receptor-binding domain of its Spike protein and its cellular receptor, angiotensin-converting enzyme-2 (ACE2). …”
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21348
Theoretical understanding of water splitting by analyzing nanocatalyst photoabsorption spectra
Published 2025-02-01“…In a photoelectrochemical cell used for water splitting, the surface states of optically and chemically dominant species affect the catalysts’ performance. …”
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21349
Novel 4-aminoquinazoline derivatives as new leads for anticancer drug discovery
Published 2015-09-01“…All the newly synthesized compounds were evaluated for in vitro cytotoxic activity against the breast cancer cell line MCF-7. Seven of the novel compounds exhibited higher activity than the reference drug doxorubicin. …”
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21350
Infantile (congenital) anaplastic intracranial solitary fibrous tumor/hemangiopericytoma—A case report with brief literature review
Published 2023-07-01“…The microscopy revealed a spindle cell tumor arranged in a patternless pattern with variable cellularity, increased mitosis, and areas of coagulative necrosis. …”
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21351
Negative Ion Beam Emittance Calculations
Published 2020-03-01“…The aim of the paper was to study changes of produced beam quality (described by its emittance and brightness) with the geometry of the extraction system as well as extraction voltage.A two-dimensional Particle-in-Cell (PIC) method based code was applied to model Hions and electrons extraction from the ion source plasma chamber through the opening with bevelled surface. …”
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21352
Identifying key genes in cancer networks using persistent homology
Published 2025-01-01“…We integrate mutation data from six cancer types and three biological functions: DNA Repair, Chromatin Organization, and Programmed Cell Death. We systematically evaluated the impact of gene removal on topological voids ( $$\beta _2$$ structures) within the Cancer Consensus Networks. …”
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21353
Enterovirus-like particles encapsidate RNA and exhibit decreased stability due to lack of maturation.
Published 2025-02-01“…In contrast to prior studies and prevailing hypotheses, we show that insect-cell produced enterovirus VLPs include encapsidated RNA fragments with viral protein coding sequences. …”
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21354
Solu: a cloud platform for real-time genomic pathogen surveillance
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21355
C-Peptide Levels Predict the Effectiveness of Dipeptidyl Peptidase-4 Inhibitor Therapy
Published 2016-01-01“…Our study demonstrates that in patients having inadequate glycemic control, the addition of a DPP-4 inhibitor as a second oral agent to metformin monotherapy provides better glycemic control, protects β-cell reserves, and does not cause weight gain. These effects depend on baseline C-peptide levels.…”
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21356
Non-Traditional Management of the Neurogenic Bladder: Tissue Engineering and Neuromodulation
Published 2007-01-01“…Advances in the fields of nanotechnology and stem cell biology have further enhanced these tissue engineering technologies. …”
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21357
E. coli Sepsis: Red Flag for Colon Carcinoma—A Case Report and Review of the Literature
Published 2017-01-01“…E. coli strains B2 and D produce cyclomodulin toxins as part of their virulence, which interferes with the cell cycle regulation, promoting chromosomal instability, and increasing susceptibility to cancer. …”
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21358
Survival Analysis by Penalized Regression and Matrix Factorization
Published 2013-01-01“…We tried L1- (lasso), L2- (ridge), and L1-L2 combined (elastic net) penalized regression for diffuse large B-cell lymphoma (DLBCL) patients' microarray data and found that L1-L2 combined method predicts survival best with the smallest logrank P value. …”
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21359
Robert Creeley’s Refusals
Published 2014-01-01“…D’une manière analogue à celle de William Carlos Williams, dont il admirait l’écriture, Creeley pense par l’entremise de ses poèmes : « Je crois en une poésie déterminée par le langage qui la compose », déclare-t-il en 1960. …”
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21360
Concurrent Stenoocclusive Disease of Intracranial and Extracranial Arteries in a Patient with Polycythemia Vera
Published 2012-01-01“…The pathophysiology of moyamoya remains obscure, but hematologic disorders, notably sickle-cell anemia, have been associated in some cases. …”
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