Severe Myositis, Myocarditis, and Myasthenia Gravis with Elevated Anti-Striated Muscle Antibody following Single Dose of Ipilimumab-Nivolumab Therapy in a Patient with Metastatic M... by Mahdieh Fazel, Patrick M. Jedlowski

“…Immune checkpoint inhibitors targeting programmed cell death protein 1 and cytotoxic T-lymphocyte associated protein 4 have improved survival in patients with metastatic melanoma, especially in combination (i.e., ipilimumab-nivolumab). …”
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Effect of Addition of Taurine on the Liquid Storage (5°C) of Mithun (Bos frontalis) Semen by P. Perumal, Kezhavituo Vupru, C. Rajkhowa

“…It was concluded that the possible protective effects of taurine on sperm parameters are from enhancing the function of antioxidant enzymes, preventing efflux of cholesterol from cell membranes and decreased MDA production.…”
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Cloning, Characterization and Expression Pattern of the Ovarian Cytochrome P450 Cyp19a1aGene in Gonadal Developmental Period of Cobaltcap Silverside Hypoatherina tsurugae by Dilip Kumar Bej

“…The upregulation of the cyp19a1a transcription factor is required for granulosa cell differentiation and ovarian maintenance. 1630 bp of cyp19a1 mRNA transcript of Hypoatherina tsurugae was cloned and sequenced. …”
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Effects of D128N Mutation on OsSERK2 in Xa21-Mediated Immune Complex: An In Silico Study by Raghib Ishraq Alvy, M. H. M. Mubassir, Mohd Firdaus Abdul-Wahab, Salehhuddin Hamdan

“…Receptor-like kinases (RLKs) are plant proteins that form signaling circuits to transduce information through the plant cell membrane to the nucleus and activate processes that direct growth, development, stress response, and disease resistance. …”
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Persistently increased post-stress activity of paraventricular thalamic neurons is essential for the emergence of stress-induced alterations in behaviour. by Anna Jász, László Biró, Zsolt Buday, Bálint Király, Orsolya Szalárdy, Krisztina Horváth, Gergely Komlósi, Róbert Bódizs, Krisztina J Kovács, Marco A Diana, Balázs Hangya, László Acsády

“…Activation of the key forebrain targets (basolateral amygdala, prelimbic cortex, and nucleus accumbens) that mediate defensive behaviour has also been reduced by this post-stress inhibition. Reduction of PVT/CR+ cell activity 5 days later remained still effective in ameliorating stress-induced changes in spontaneous behaviour. …”
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Taxonomy and Polyphasic Characterization of Alkaline Amylase Producing Marine Actinomycete Streptomyces rochei BTSS 1001 by Aparna Acharyabhatta, Siva Kumar Kandula, Ramana Terli

“…The presence of iso-C15 : 0, anteiso-C15 : 0, iso-C16 : 0, and anteiso-C17 : 0 as the major cellular fatty acids, LL-diaminopimelic acid as the characteristic cell wall component, and menaquinones MK-9H(6) and MK-9H(8) as the major isoprenoid quinones is attributed to the strain BTSS 1001 belonging to the genus Streptomyces. …”
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Periodic Catatonia Marked by Hypercortisolemia and Exacerbated by the Menses: A Case Report and Literature Review by Samantha Zwiebel, Alejandro G. Villasante-Tejanos, Jose de Leon

“…Through 4 catatonic episodes (one lasting 17 months) there were menstrual exacerbations of catatonia and increases in 4 biological variables: (1) creatine kinase (CK) up to 4,920 U/L, (2) lactate dehydrogenase (LDH) up to 424 U/L, (3) late afternoon cortisol levels up to 28.0 mcg/dL, and (4) white blood cell (WBC) counts up to 24,200/mm3 with neutrophilia without infections. …”
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Standing at Cultural Crossroads: Erskine Nicol’s Representations of Ireland by Amélie Dochy

“…Ces déviations témoignent de nouvelles influences sur le travail du peintre, qui sont celles des traditions anglaises ou irlandaises. Cette analyse montre donc en quoi le travail du peintre se trouve au carrefour de multiples influences culturelles.…”
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Role of Stat3 in Skin Carcinogenesis: Insights Gained from Relevant Mouse Models by Everardo Macias, Dharanija Rao, John DiGiovanni

“…Stat3 plays critical roles in various biological activities including cell proliferation, migration, and survival. Studies using keratinocyte-specific Stat3-deficient mice have revealed that Stat3 plays an important role in skin homeostasis including keratinocyte migration, wound healing, and hair follicle growth. …”
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Mitochondrial DNA: A New Predictor of Diabetic Kidney Disease by Yajing Huang, Jingwei Chi, Fanxiang Wei, Yue Zhou, Yihai Cao, Yangang Wang

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The spatial buildup of nonlinear compression in the cochlea by Kostas Kondylidis, Kostas Kondylidis, Anna Vavakou, Anna Vavakou, Marcel van der Heijden

“…In the mammalian cochlea, the transduction from vibrations to inner hair cell receptor currents is preceded by a stage of mechanical pre-processing that involves a rapid, strongly nonlinear compression. …”
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Advocating the use of risk-based online single submission (OSS) to MSMES in Sukabumi district by Alfhi Fusvita Cahya, Hardi Warsono, Kismartini Kismartini

“…However, there are still things that need to be optimized because of the obstacles encountered, including the lack of coordination and socialization between the agency and business actors, inadequate internet network in the hinterland, not all of them have computers or Android-based cell phones for can access OSS, central and regional policies are not yet fully integrated, server down occurs frequently, and OSS upgrades are still frequently carried out. …”
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Correction: Rakhshandeh et al. Protective Effect of <i>Portulaca oleracea</i> on Streptozotocin-Induced Type I Diabetes-Associated Reproductive System Dysfunction and Inflammation.... by Hassan Rakhshandeh, Hamed Rajabi Khasevan, Anella Saviano, Mohammad Reza Mahdinezhad, Vafa Baradaran Rahimi, Sajjad Ehtiati, Leila Etemad, Alireza Ebrahimzadeh-bideskan, Francesco Maione, Vahid Reza Askari

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Circulating Endothelial Microparticles: A Key Hallmark of Atherosclerosis Progression by Keshav Raj Paudel, Nisha Panth, Dong-Wook Kim

“…The prominent MPs present in blood are endothelial microparticles (EMPs) described as complex submicron (0.1 to 1.0 μm) vesicles like structure, released in response to endothelium cell activation or apoptosis. EMPs possess both physiological and pathological effects and may promote oxidative stress and vascular inflammation. …”
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Causal role of ischemic heart disease in ovarian cancer subtypes by Jianhai Chen, Huabin He, Ling Gao

“…No associations were observed for serous, mucinous, or clear cell ovarian cancers. Sensitivity analyses confirmed robust findings. …”
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Impaired Inflammatory Response to LPS in Type 2 Diabetes Mellitus by Lusine Khondkaryan, Sona Margaryan, David Poghosyan, Gayane Manukyan

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Machine Learning and Medical Data: Predicting ICU Mortality and Re-admission Risks by Runia Roy, Ulya Bayram

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With great power, comes great responsibility: the importance of broadly measuring Fc-mediated effector function early in the antibody development process by Silvia Crescioli, Shashi Jatiani, Lenny Moise

“…Given the breadth of effector functions antibodies can deploy and the close interplay between the antibody Fab and Fc functional domains, it is important to conduct a comprehensive evaluation of Fc-mediated functions using an array of antigen-specific biophysical and cell-mediated functional assays. Here, we review antibody and Fc receptor properties that influence Fc effector functions and discuss their implications on development of safe and efficacious antibody therapeutics.…”
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Design, Synthesis and Potential Anti-Proliferative Activity of Some Novel 4-Aminoquinoline Derivatives by Ghorab Mostafa M., Al-Said Mansour S., Arafa Reem K.

“…All the newly synthesized comounds were tested for in vitro antiproliferative activity against the MCF-7 breast cancer cell line. Seventeen of the novel compounds showed higher activity than the reference drug doxorubicin. …”
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Influence of Starkeya novella on Mechanical and Microstructural Properties of Cement Mortars by Onesmus Mulwa Munyao, Joseph Karanja Thiong’o, Jackson Muthengia Wachira, Daniel Karanja Mutitu, Romano Mwirichia

“…Bacterial solution of 1.0 × 107 cell/mL concentration was used as either mix water, curing media, or both. …”
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