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21221
Mechanisms of Copper-Induced Autophagy and Links with Human Diseases
Published 2025-01-01“…However, excess intracellular copper can induce cell death due to its potential to catalyze the generation of reactive oxygen species, thus copper homeostasis is strictly regulated. …”
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21222
Application Strategies of Super-Enhancer RNA in Cardiovascular Diseases
Published 2025-01-01“…These regions play a pivotal role in regulating genes involved in cell identity and disease progression. This article reviews the characteristics of seRNAs, their expression patterns, and regulatory mechanisms in the cardiovascular system. …”
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21223
Modern approaches to artificial gene synthesis: aspects of oligonucleotide synthesis, enzymatic assembly, sequence verification and error correction
Published 2018-08-01“…Development of system biology has allowed forming a deeper understanding of the functions and relationship of natural biological models, as well as of the computational models describing processes at the cell and system levels. Combination of these factors has created an opportunity for conscious changes of natural biological systems. …”
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21224
Immunomodulatory Properties of HLA-G in Infectious Diseases
Published 2014-01-01“…The relevance of studies on HLA-G expression lies in the well known inhibitory effect of this molecule on all cell types involved in innate and adaptive immunity, favoring escape from immune control. …”
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21225
Stevens-Johnson Syndrome and Erythema Multiforme Induced by Imiquimod 5% Cream
Published 2025-01-01“… Introduction: Topical imiquimod is a safe and effective treatment for actinic keratoses, superficial basal cell carcinomas and anogenital warts. The treatment is commonly associated with local inflammatory reactions, while systemic side effects are rare and generally mild. …”
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21226
Therapeutic Targeting of Fibroblast Growth Factor Receptors in Gastric Cancer
Published 2015-01-01“…Preclinical studies in animal models suggest that multitargeted tyrosine kinase inhibitors (TKIs), including FGFR inhibitor, suppress tumor cell proliferation and delay tumor progression. Several TKIs are now being evaluated in clinical trials as treatment for metastatic or unresectable GC harboring FGFR2 amplification.…”
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21227
Proteomics of the Dark-Ventral-Patch Sexual Signal in Male Red Deer
Published 2025-01-01“…In this study, we used a shotgun proteomic approach to investigate whether the ventral patch hair retains proteins on its surface that could reveal metabolic and cell-signaling adaptations potentially related to reproductive activity. …”
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21228
An atlas of metabolites driving chemotaxis in prokaryotes
Published 2025-02-01“…Our analysis reveals that (i) not all chemical classes trigger chemotaxis equally, in particular, amino acids and benzenoids are much stronger attractants than carbohydrates; (ii) over one-quarter of attractants tested are not used for growth but solely act as chemotactic signals; (iii) the prokaryote’s origin matters, as terrestrial strains respond to 50% more chemicals than those originating from human or marine biomes; (iv) repellents affect cell behaviour at concentrations 10-fold higher than attractants; (v) the effect of large molecules and the behaviour of bacteria other than Proteobacteria have been largely overlooked. …”
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21229
A Study of Deep Neural Network Controller-Based Power Quality Improvement of Hybrid PV/Wind Systems by Using Smart Inverter
Published 2020-01-01“…In this paper, the photovoltaic cell and wind energy systems are investigated under various weather conditions. …”
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21230
Analysis of crafts (Kriya) creative industries: a case study of policy development in Banten Indonesia
Published 2023-09-01“…The results of the study showing the position of the Craft Industry based on local potential in Banten Province depend on cell 5a (2.04; 2.47) so that the strategy taken is a stable growth (Growth) strategy, namely concentration through horizontal assistance. …”
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21231
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21232
Brain lateralisation feature extraction and ant colony optimisation‐bidirectional LSTM network model for emotion recognition
Published 2022-02-01“…Unlike other LSTM network models, this model improves performance by applying more weight values that are valid for emotion recognition in the current LSTM cell state using past and future biosignal information and combining ACO to find the optimal combination of emotion recognition features among many features. …”
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21233
Stability and Convergence of Nuclear Detonations in White Dwarf Collisions
Published 2025-01-01“…We study the effects of grid resolution and the limiting of temperature, energy generation, and reactants for different stellar masses, separations, magnetic fields, initial compositions, detonation mechanisms, and limiter parameters across a range of cell sizes from 1 to 100 km. Our results set bounds on the parameter space of limiter amplitudes for which both temperature- and energy-limiting procedures yield consistent and monotonically convergent solutions. …”
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21234
Analysis of doxorubicin and fullerenol in rat serum by micellar electrokinetic capillary chromatography
Published 2024-09-01“…The separation was carried out in a capillary (48.5–40 cm to the detector – 50 µm id fused-silica capillary with bubble cell, 150 µm) at an applied voltage of 25 kV and temperature of 25 °C. …”
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21235
Research on the Fast Charging Strategy of Power Lithium-Ion Batteries Based on the High Environmental Temperature in Southeast Asia
Published 2024-12-01“…The maximum charging capacity of the cell is exerted within different SOCs and temperature ranges. …”
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21236
DIFFERENT AMOUNT OF THROMBOCYTES ON BLOOD STORAGE FOR 24 HOURS IN ROOM AND REFRIGERATOR
Published 2019-12-01“…Background: Storage is a pre-analytic part that plays a role in maintaining cell quality functionally. Examination of platelet count is influenced by pre-analytic factors, namely time and temperature since specimen collection so that the specimen storage guidelines are needed to obtain accurate laboratory results. …”
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21237
Blood Plasma of Patients with Parkinson’s Disease Increases Alpha-Synuclein Aggregation and Neurotoxicity
Published 2016-01-01“…Compared with NS plasma, PD plasma added to primary neuron cultures caused more cell death in the presence of extracellular α-syn. …”
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21238
Analysis of Optimal Load Management Using a Stand-Alone Hybrid AC/DC Microgrid System
Published 2023-01-01“…The efficient solution for transmitting power at the lowest energy cost is configuration 1 (solar + fuel cell + battery + wind + diesel generator) which is found to be the optimal solution for supplying energy with 0% unmet load at the least cost of energy, which is at 24.91 Rs/kWh. …”
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21239
Novel IL2RG gene mutation causing primary combined immunodeficiency disease: A case report and literature review
Published 2024-09-01“…Immunological assessment revealed abnormalities in immunoglobulin levels and T-cell distribution, suggesting a potential immune deficiency. …”
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21240
Lipid Membrane Self-Assembly and Synthesis in the Lab by Rapid, Low-Cost Microfluidics Approaches
Published 2023-12-01“…The main uses for liposomes are in drug delivery systems and as animal cell models. From the initial research into lipid membrane science, to the systematic literature review using Web of Science, to refining the project scope, to the description of the method, this project follows the process of developing a method for lipid membrane self-assembly and synthesis in the lab. …”
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