The Roles of FOXO1 in Periodontal Homeostasis and Disease by Liang Ren, Jing Yang, Jun Wang, Xuedong Zhou, Chengcheng Liu

“…The transcription factor forkhead box protein O1 (FOXO1) is a key regulator of a number of cellular processes, including cell survival and differentiation, immune status, reactive oxygen species (ROS) scavenging, and apoptosis. …”
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Green Route for Efficient Synthesis of Novel Amino Acid Schiff Bases as Potent Antibacterial and Antifungal Agents and Evaluation of Cytotoxic Effects by Harshita Sachdeva, Rekha Saroj, Sarita Khaturia, Diksha Dwivedi, Om Prakash Chauhan

“…Compounds have also been evaluated for cytotoxic effects against human colon cancer cell line Colo205.…”
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Potentiating intratumoral therapy with immune checkpoint inhibitors: shifting the paradigm of multimodality therapeutics by B.E. Nelson, A. Naing, S. Fu, R.A. Sheth, R. Murthy, S. Piha-Paul

“…The tumor microenvironment plays a critical role in immunotherapy resistance, characterized by immune cell composition, regulatory factors, and tumor mutational burden. …”
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Pressure-anisotropy-mediated Helical Dynamo in Turbulent Collisionless Plasmas by Z. H. Zhao, W. Q. Yuan, L. X. Li, X. W. Zhu, X. X. Jin, S. P. Zhu, X. T. He, B. Qiao

“…By means of theoretical modeling that includes indispensable kinetic effects and fully kinetic particle-in-cell simulation that contains sufficient scale separation, we self-consistently show that the collisionless large-scale dynamo is quite efficient and the system-scale coherent fields can be generated from kinetic-scale seeds under a turbulent helical drive. …”
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Early Posttransplant Isolated v1 Lesion Does Not Need to Be Treated and Does Not Lead to Increased Fibrosis by Irfan Moinuddin, Bijin Thajudeen, Amy Sussman, Machaiah Madhrira, Erika Bracamonte, Mordecai Popovtzer, Pradeep V. Kadambi

“…Although it is suggested that most cases of isolated v1 lesions will respond to corticosteroids or T cell depleting therapies, some cases will improve with conservative management. …”
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Chemical tools to define and manipulate interferon-inducible Ubl protease USP18 by Griffin J. Davis, Anthony O. Omole, Yejin Jung, Wioletta Rut, Ronald Holewinski, Kiall F. Suazo, Hong-Rae Kim, Mo Yang, Thorkell Andresson, Marcin Drag, Euna Yoo

“…We further demonstrate that USP18 ABPs can be utilized to profile differential activities of USP18 in lung cancer cell lines, providing a strategy that will help define the activity-related landscape of USP18 in different disease states and unravel important (de)ISGylation-dependent biological processes.…”
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Competing Endogenous RNA: The Key to Posttranscriptional Regulation by Rituparno Sen, Suman Ghosal, Shaoli Das, Subrata Balti, Jayprokas Chakrabarti

“…This brief review focuses on the molecular mechanism of ceRNA as part of the complex post-transcriptional regulatory circuit in cell and the impact of ceRNAs in development and disease.…”
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Recent advances in L-Asparaginase enzyme production and formulation development for acrylamide reduction during food processing by Arindam Jana, Soumyajit Biswas, Ritu Ghosh, Rahul Modak

“…L-asparagine is an essential amino acid for cell growth and common constituent of all the proteins. …”
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Consequences of Hyperoxia and the Toxicity of Oxygen in the Lung by William J. Mach, Amanda R. Thimmesch, J. Thomas Pierce, Janet D. Pierce

“…Activated alveolar capillary endothelium is characterized by increased adhesiveness causing accumulation of cell populations such as neutrophils, which are a source of ROS. …”
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Receptor for Advanced Glycation End Products and Its Involvement in Inflammatory Diseases by Yaw Kuang Chuah, Rusliza Basir, Herni Talib, Tung Hing Tie, Norshariza Nordin

“…These effects endow RAGE with the role in the signal transduction from pathogen substrates to cell activation during the onset and perpetuation of inflammation. …”
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Peroxisome Proliferator-Activated Receptors in Female Reproduction and Fertility by Maurizio Vitti, Giovanna Di Emidio, Michela Di Carlo, Gaspare Carta, Andrea Antonosante, Paolo Giovanni Artini, Annamaria Cimini, Carla Tatone, Elisabetta Benedetti

“…PPARs act as ligand activated transcription factors and regulate metabolic processes such as lipid and glucose metabolism, energy homeostasis, inflammation, and cell proliferation and differentiation. All PPARs isotypes are expressed along the hypothalamic-pituitary-gonadal axis and are strictly involved in reproductive functions. …”
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Natural Products for Cancer Therapy: A Review of Their Mechanism of Actions and Toxicity in the Past Decade by Yasir Osman Ali Abdalla, Bavani Subramaniam, Shaik Nyamathulla, Noorasyikin Shamsuddin, Norhafiza M. Arshad, Kein Seong Mun, Khalijah Awang, Noor Hasima Nagoor

“…Besides, critical analysis of their molecular targets and underlying mechanisms on multiple cancer cell lines, an in-depth probe of their toxicological screening on rodent models is outlined as well to observe the prevalence of their toxicity towards host. …”
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Protonation and Photocatalytic Activity of the Rb2La2Ti3O10 Layered Oxide in the Reaction of Hydrogen Production by Ivan A. Rodionov, Iuliia P. Sokolova, Oleg I. Silyukov, Alena A. Burovikhina, Sergey A. Fateev, Irina A. Zvereva

“…Each of these phase transformations is accompanied not only by the contraction of the interlayer distance but also by the displacement of adjacent perovskite layers by 1/2 of the cell parameter which results in the change in the space group. …”
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A Case of Pulmonary Sarcoma with Significant Extension into the Right Lung by Yoshiaki Inoue, Yotaro Izumi, Kenjiro Sakaki, Keiko Abe, Teruaki Oka, Jun-Ichi Tamaru, Ato Sugiyama, Kohei Aoki, Hiroki Fukuda, Masatoshi Gika, Kazuhito Imanaka, Mitsuo Nakayama

“…Biopsy of this lesion supported suspicions of sarcoma or spindle cell carcinoma. Contrast-enhanced CT showed that the mass extended to and obstructed the right main pulmonary artery. …”
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Polarization-Insensitive, High-Efficiency Metasurface with Wide Reception Angle for Energy Harvesting Applications by Abdulrahman Ahmed Ghaleb Amer, Nurmiza Othman, Mohammed M. Bait-Suwailamn, Syarfa Zahirah Sapuan, Ali Ahmed Ali Salem, Adeb Salh

“…To validate the design, a 5 × 5-unit cell array of the MS structure was fabricated and experimentally tested, demonstrating excellent agreement between simulation and measurement results. …”
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Electroimpedance Spectroscopy for the Measurement of the Dielectric Properties of Sodium Chloride Solutions at Different Glucose Concentrations by Stefano Sbrignadello, Andrea Tura, Paolo Ravazzani

“…The sodium chloride solution (either saline physiological solution) was chosen since it has similarities to blood but no cell components, which may be confounding factors in this study. …”
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Application of Monoclonal Antibodies against Bioactive Natural Products: Eastern Blotting and Preparation of Knockout Extract by Hiroyuki Tanaka, Osamu Morinaga, Takuhiro Uto, Shunsuke Fuji, Frederick Asare Aboagye, Nguyen Huu Tung, Xiao Wei Li, Waraporn Putalun, Yukihiro Shoyama

“…The immunoaffinity concentration of glycyrrhizin was determined by immunoaffinity column conjugated with antiglycyrrhizin MAb resulting in the glycyrrhizin-knockout extract, which was determined by the synergic effect with glycyrrhizin on NO production using the cell line.…”
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A Rare Presentation of Lymphoma of the Cervix with Cross-Sectional Imaging Correlation by Brinda Rao Korivi, Corey T. Jensen, Madhavi Patnana, Keyur P. Patel, Tharakeswara K. Bathala

“…A 43-year-old asymptomatic female with a history of dual hit blastic B-cell lymphoma/leukemia in complete remission presented with an incidental cervical mass, which was initially felt to represent a cervical fibroid on computed tomography (CT). …”
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Role of 3-mercaptopyruvate sulfurtransferase in cancer: Molecular mechanisms and therapeutic perspectives by Ka Zhang, Yi-Wen Zhu, Ao-Qi Tang, Ze-Tao Zhou, Yi-Lun Yang, Zi-Hui Liu, Yan Li, Xiao-Yi Liang, Zhi-Fen Feng, Jun Wang, Tong Jiang, Qi-Ying Jiang, Dong-Dong Wu

“…Alternation of H2S level has been widely demonstrated to induce an array of disturbances in important cancer cell signaling pathways. As a result, the effects of H2S-catalyzing enzymes in cancers also attract widspread attention. 3-mercaptopyruvate sulfurtransferase (3-MST) is privileged to be one of them. …”
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NIR-activated catechol-functionalized nanodiamond nanofibers for accelerating on-demand MRSA and E. coli biofilm eradication by Hyeonseo Park, Tejal V. Patil, Jieun Lee, Hojin Kim, Seong-Jun Cho, Ki-Taek Lim

“…Additionally, the catechol groups in PDA provided strong cell adhesion and high biocompatibility on the nanofiber surface. …”
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