Melanoma Mimicking Malignant Peripheral Nerve Sheath Tumor with Spread to the Cerebellopontine Angle: Utility of Next-Generation Sequencing in Diagnosis by Katie Fox Hanson, Paul Birinyi, Ronald Walker, Constantine Raptis, Rebecca Chernock, Jeroen Coppens, Katherine E. Schwetye

“…Cutaneous spindle cell malignancy is associated with a broad differential diagnosis, particularly in the absence of a known primary melanocytic lesion. …”
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A guide to selecting high-performing antibodies for VAPB (UniProt ID: O95292) for use in western blot, immunoprecipitation, and immunofluorescence [version 1; peer review: 3 approv... by Maryam Fothouhi, Peter S. McPherson, Carl Laflamme, Sara González Bolívar, Riham Ayoubi, Charles Alende, Irina Shlaifer

“…Here we have characterized six VAPB commercial antibodies for western blot, immunoprecipitation, and immunofluorescence using a standardized experimental protocol based on comparing read-outs in knockout cell lines and isogenic parental controls. These studies are part of a larger, collaborative initiative seeking to address antibody reproducibility issues by characterizing commercially available antibodies for human proteins and publishing the results openly as a resource for the scientific community. …”
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Electrophoretic Deposition of Carbon Nanotubes over TiO2 Nanotubes: Evaluation of Surface Properties and Biocompatibility by Jung Eun Park, Il Song Park, Tae Sung Bae, Min Ho Lee

“…Formation of TiO2 nanotubes (TiO2 NTs) on titanium is an interesting surface modification to achieve controlled drug delivery and to promote cell growth. Carbon nanotubes (CNTs) possess excellent chemical durability and mechanical strength. …”
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Staged, Open, No-Ischemia Nephron-Sparing Surgery for Bilateral-Multiple Kidney Tumors in a Patient with Birt-Hogg-Dubé Syndrome by Ahmet Tefekli, Ayşe Deniz Akkaya, Kamil Peker, Terman Gümüş, Metin Vural, Fatin Cezayirli, Ahmet Musaoglu, Tarık Esen

“…The morbidity and mortality of the affected patients is determined by the presence of the kidney tumors, which tend to be multifocal and bilateral, as observed in other hereditary kidney cancer syndromes like von Hippel-Lindau disease, familial leiomyomatosis, and hereditary papillary renal cell carcinoma. Herein, a patient with BHDS, presenting with synchronous bilateral multiple kidney tumors, is reported. …”
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Comprehensive guide for epigenetics and transcriptomics data quality control by Arianna Comendul, Frederique Ruf-Zamojski, Colby T. Ford, Pankaj Agarwal, Elena Zaslavsky, German Nudelman, Manoj Hariharan, Aliza Rubenstein, Hanna Pincas, Venugopalan D. Nair, Adam M. Michaleas, Philip D. Fremont-Smith, Darrell O. Ricke, Stuart C. Sealfon, Christopher W. Woods, Kajal T. Claypool, Rafael Jaimes, III

“…The interrogation of the epigenome and transcriptome cascade requires analyzing disparate datasets from multiple assay types, often at single-cell resolution, derived from the same biospecimen. …”
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A ChIP-Seq Data Analysis Pipeline Based on Bioconductor Packages by Seung-Jin Park, Jong-Hwan Kim, Byung-Ha Yoon, Seon-Young Kim

“…Nowadays, huge volumes of chromatin immunoprecipitation-sequencing (ChIP-Seq) data are generated to increase the knowledge on DNA-protein interactions in the cell, and accordingly, many tools have been developed for ChIP-Seq analysis. …”
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Peroxisome Proliferator-Activated Receptor α Plays an Important Role in the Expression of Monocyte Chemoattractant Protein-1 and Neointimal Hyperplasia after Vascular Injury by Yu Peng, Qiang Li, Lu Zhang, Ming Bai, Zheng Zhang

“…It modulates smooth muscle cell proliferation and inflammatory cytokines in vitro. …”
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Pancytopenia in a Patient with Rendu-Osler-Weber Syndrome and Uncommon Vascular Abnormalities by Nicolò Binello, Antonio Gasbarrini, Eleonora Gaetani

“…The patient underwent coil embolization of the splenic artery aneurysm, followed by rapid and sustained increase of white blood cell and platelet count. Splenic artery aneurysms are extremely uncommon in HHT as only anecdotal cases have been reported to date. …”
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Protective Effects of Chicken Egg Yolk Immunoglobulins (IgYs) against Vibrio vulnificus Infections by Ruizhao Cai, Ning Liu, Penghao Guo, Kang Liao, Mengzhi Li, Junyou Zhu, Shouyi Chen, Lei Chen, Bin Shu, Shaohai Qi

“…IgYs were produced by immunizing egg laying hens with inactivated whole cell bacteria. Peritoneal cytokines, blood’s bacterial load, and survival curves were obtained from both prophylactic and therapeutic mouse models. …”
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Microangiopathic Hemolytic Anemia: A Rare Complication of Acute Pancreatitis by Syedda Ayesha, Masood Muhammad Karim, Maria Ali, Abdul Hadi Shahid, Salman Naseem Adil

“…Microangiopathic hemolytic anemia (MAHA) is a rare subtype of hemolytic anemia characterized by elevated hemolytic markers and red blood cell destruction. Though uncommon, MAHA can occur as a complication of acute pancreatitis because of the associated inflammatory response. …”
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LPS-induced serum TNF production and lethality in mice: effect of L-carnitine and some acyl-derivatives by Vito Ruggiero, Claudio M. D'Urso, Claudio Albertoni, Silvia Campo, Piero Foresta, Edoardo Arrigoni Martelli

“…In this experimental model, C57BL/6 mice received 30 mg/kg LPS (E. cell 055:B5) injected intraperitoneally, while L-carnitine and its derivatives were administered according to different schedules. …”
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Microtubule flexibility, microtubule-based nucleation and ROP pattern co-alignment enhance protoxylem microtubule patterning by Bas Jacobs, Marco Saltini, Jaap Molenaar, Laura Filion, Eva E. Deinum

“…The development of the water transporting xylem tissue in plants involves an intricate interplay of Rho-of-Plants (ROP) proteins and cortical microtubules to generate highly functional secondary cell wall patterns, such as the ringed or spiral patterns in early-developing protoxylem. …”
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Lightweight Photovoltaic Composite Structure on Stratospheric Airships by Xinyun Zhang, Kangwen Sun, Dongdong Xu, Shijun Guo

“…In order to improve the flexibility of the solar cell, we studied the mechanical properties in the different thicknesses of the honeycomb core for LPCS by FEM software and three-point bending test, and we also launched experiments to measure the temperature difference between upper and lower surfaces of the LPCS test samples under different solar radiation flux conditions. …”
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TNPO1-Mediated Nuclear Import of FUBP1 Contributes to Tumor Immune Evasion by Increasing NRP1 Expression in Cervical Cancer by BiKang Yang, Jing Chen, YinCheng Teng

“…In vitro, functional experiments showed that knockdown of FUBP1 inhibited CC cell proliferation and migration. Therefore, FUBP1 plays a prooncogenic function in CC progression. …”
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Anti-inflammatory actions of acupuncture by Freek J. Zijlstra, Ineke van den Berg-de Lange, Frank J. P. M. Huygen, Jan Klein

“…The complex interactions with substance P, the analgesic contribution of β-endorphin and the balance between cell-specific pro-inflammatory and anti-inflammatory cytokines tumour necrosis factor-α and interleukin-10 are discussed.…”
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Aortic Dissection Occurring 18 Months after Successful Endovascular Repair in an Anatomically Difficult Case of Abdominal Aortic Aneurysm by Satoshi Yamamoto, Katsuyuki Hoshina, Yutaka Takazawa, Hiroyuki Okamoto, Kunihiro Shigematsu, Tetsuro Miyata, Toshiaki Watanabe

“…The luminal surface of the stent graft was almost completely covered with a transparent film with an endothelial cell lining, which might reflect the tissue regeneration observed on histological examination. …”
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Recurrent Struma Ovarii Presented with High Levels of Thyroglobulin by Christiana Oikonomou, Nikol Spathari, Stavroula Doumoulaki, Antonella Koutela, Christos Stagkoglou, Dimitris Keramidaris

“…Struma ovarii are rare ovarian tumors, of monodermal germ cell origin, containing predominantly thyroid tissue. …”
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Iron and ferroptosis in kidney disease: molecular and metabolic mechanisms by Wenjie Wang, Jingdi Chen, Liying Zhan, Handong Zou, Lu Wang, Mengmeng Guo, Hang Gao, Jing Xu, Wei Wu

“…Over the past decade, ferroptosis’ role in mediating the development and progression of renal disorders, such as acute kidney injury (renal ischemia-reperfusion injury, drug-induced acute kidney injury, severe acute pancreatitis induced acute kidney injury and sepsis-associated acute kidney injury), chronic kidney disease (diabetic nephropathy, renal fibrosis, autosomal dominant polycystic kidney disease) and renal cell carcinoma, has come into focus. Thus, knowing kidney iron metabolism and ferroptosis regulation may enhance disease therapy. …”
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Successful Treatment of Actinic Keratosis with Kanuka Honey by Saras Mane, Joseph Singer, Andrew Corin, Alex Semprini

“…Actinic keratoses form as rough, scaly plaques on sun-exposed areas; they can be an important step in premalignant progression to squamous cell cancer of the skin. Currently, pharmacological treatments consist of topical immunomodulatory agents with poor side effect profiles. …”
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Bilateral Lower Cervical Bifurcation of the Common Carotid Artery by Lokman Uzun, Numan Kokten, Adem Kilicaslan, Bulent Tasel, M. Tayyar Kalcioglu, Muhammet Tekin

“…Total laryngectomy and right selective neck dissection was performed to the patient with the diagnosis of squamous cell carcinoma of the larynx. During the neck dissection, carotid bifurcation was detected in common border of Level 3 and Level 4 of the neck.…”
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