The Management of Classical Hodgkin's Lymphoma: Past, Present, and Future by S. E. Richardson, C. McNamara

“…Even in relapse, CHL patients can be salvaged with high dose chemotherapy and autologous haematopoietic stem cell transplantation (ASCT). Challenges remain, however, in finding new strategies to manage the small number of patients who continue to relapse or progress. …”
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Vastly different energy landscapes of the membrane insertions of monomeric gasdermin D and A3 by Viktoria Korn, Kristyna Pluhackova

“…Abstract Gasdermin D and gasdermin A3 belong to the same family of pore-forming proteins and executors of pyroptosis, a form of programmed cell death. To unveil the process of their pore formation, we examine the energy landscapes upon insertion of the gasdermin D and A3 monomers into a lipid bilayer by extensive atomistic molecular dynamics simulations. …”
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Energy Saving in Data Processing and Communication Systems by Giuseppe Iazeolla, Alessandra Pieroni

“…Dp systems are also used in the government of Tlc systems, which, besides requiring Dp electrical power, also require Tlc-specific power, both for mobile networks (with their cell-phone towers and associated subsystems: base stations, subscriber stations, switching nodes, etc.) and for wired networks (with their routers, gateways, switches, etc.). …”
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Retroperitoneal Lymph Node Dissection as Primary Treatment for Metastatic Seminoma by Brian Hu, Siamak Daneshmand

“…Retroperitoneal lymph node dissection (RPLND) is a standard treatment for nonseminomatous germ cell tumors (NSGCT) that has minimal long-term morbidity. …”
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How to Quantify Nosema Spores Infection Rate in a Honey Bee Colony by Ashley N. Mortensen, Cameron Jack, Meghan McConnell, Liana Teigen, Jamie Ellis

“… Nosema are single-celled fungal parasites that infect various animal hosts. …”
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Genetics of Cerebral Vasospasm by Travis R. Ladner, Scott L. Zuckerman, J Mocco

“…It is thought that an inflammatory cascade initiated by extravasated blood products precipitates CV, disrupting vascular smooth muscle cell function of major cerebral arteries, leading to vasoconstriction. …”
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Iron Loading and Overloading due to Ineffective Erythropoiesis by Toshihiko Tanno, Jeffery L. Miller

“…Erythropoiesis describes the hematopoietic process of cell proliferation and differentiation that results in the production of mature circulating erythrocytes. …”
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Chemical Speciation of Thorium in Marine Biogenic Particulate Matter by Katsumi Hirose

“…Our findings suggest that the SOL in PM is a nonmetal-specific chelator originating from the cell surface of microorganisms.…”
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New Brightener for Zn-Fe Alloy Plating from Sulphate Bath by B. M. Praveen, T. V. Venkatesha

“…Zn-Fe alloy electrodeposition was carried out in the presence of condensation product 2-{[(1E)-(3,4-dimethoxyphenyl)methylidene]amino}-3-hydroxypropanoic acid formed between veratraldehyde and serine in acid sulphate bath. Hull cell was used for optimizing the operating parameters and bath constituents. …”
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Systemic and Local CC Chemokines Production in a Murine Model of <emph>Listeria monocytogenes</emph> Infection

“…The ratio of brain-to-serum concentration of monocyte chemoattractant protein 1 (MCP-1) remained the same as in the control animals, while it was lower in the infected mice, both in the case MIP-1<mml:math> <mml:mi>&#x03B1;</mml:mi> </mml:math> and in the case of regulated on activation, normal T cell expressed and secreted (RANTES). This is in correlation with slight inflammatory infiltrates found in the brain tissue early in infection.…”
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Palmitoylation as a Functional Regulator of Neurotransmitter Receptors by Vladimir S. Naumenko, Evgeni Ponimaskin

“…From the functional point of view, palmitoylation affects a wide span of neurotransmitter receptors activities including their trafficking, sorting, stability, residence lifetime at the cell surface, endocytosis, recycling, and synaptic clustering. …”
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Design and Development of Biosensors for the Detection of Heavy Metal Toxicity by Graziella L. Turdean

“…A panel of examples of biosensors: enzyme-, DNA-, imuno-, whole-cell-based biosensors were systematised depending on the reaction type, transduction signal, or analytical performances. …”
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An Apparent Achilles Heel of the NFL: Have Achilles Tendon Injuries Significantly Increased to Unacceptably High Incidence Levels in the NFL and if so, why? A Clinical Insight by Timothy E Hewett, Chad D Lavender, Andrew L Schaver

“…Many if not most of us watched in utter disbelief and horror last September 11th as Aaron Rogers, the newly acquired $75 million dollar quarterback with the New York Jets just 4 snaps into the new season, suffered an Achilles Tendon ruptures (ATR) in his inaugural game on nationally televised Monday Night Football with his new and excited team and demanding fanbase. With cell phones in hand, we watched as our X apps lit up with claims of an excess of ATRs in the NFL in recent years and much of the blame placed on the new rubberized turf surfaces in place in most of the NFL stadiums. …”
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Role of PPARα in the Control of Torpor through FGF21-NPY Pathway: From Circadian Clock to Seasonal Change in Mammals by Norio Ishida

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Mediating Roles of PPARs in the Effects of Environmental Chemicals on Sex Steroids by Qiansheng Huang, Qionghua Chen

“…Their interactions with three types of PPARs are classified by various data from transcript profiles, PPRE reporter in cell line, in silico docking, and gene silencing. …”
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State of the art and new directions using DNA and other molecular markers in forensic entomology by David Haymer

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Temozolomide-Induced Myelodysplasia by Ethan A. Natelson, David Pyatt

“…TMZ is an orally active imidazotetrazine which methylates guanine residues in DNA, ultimately causing single and double-strand DNA breaks leading to apoptotic cell death. TMZ does not chemically cross-link DNA and is considered a nonclassical alkylating agent, similar in structure and activity to dacarbazine. …”
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PROTAC technology for prostate cancer treatment by Zhen Wang, Dingpeng Zhang, Hiroyuki Inuzuka, Wenyi Wei

“…The metastatic spread of PrCa is the primary cause of mortality, causing cancer cell dissemination to distant sites, such as bones, the pelvis, and various visceral organs. …”
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One-Pot Synthesis of Novel Furochromone and Oxazocine Derivatives as Promising Antitumor Agents with Their Molecular Docking Studies by Rita M. Borik

“…The obtained derivatives of novel furochromone and oxazocine derivatives were evaluated as promising antitumor agents against panel of two human cell lines, hepatocellular carcinoma (HEPG2) and breast carcinoma (MCF7). …”
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Prediction of Matrix Failure in Fibre Reinforced Polymer Composites by J. Wang, W. K. Chiu

“…For failure of typical neat resin, significant improvement of prediction accuracy compared with measured material data is demonstrated. For a unit cell with a fibre and surrounding matrix with typical material properties, a FEM analysis indicates a significant improvement in prediction accuracy in the pure shear load case and a marginal improvement in the biaxial tensile load case. …”
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