Serum Soluble Interleukin-2 Receptor Does Not Differentiate Complex Regional Pain Syndrome from Other Pain Conditions in a Tertiary Referral Setting by K. D. Bharwani, M. Dirckx, D. L. Stronks, W. A. Dik, F. J. P. M. Huygen

“…Previously, we showed that serum soluble interleukin-2 receptor (sIL-2R) levels, a marker for T-cell activation, were higher in complex regional pain syndrome (CRPS) patients than in healthy controls, suggesting pathogenic T-cell activation in CRPS. …”
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A new signature associated with anoikis predicts the outcome and immune infiltration in nasopharyngeal carcinoma by Yonglin Luo, Wenyang Wei, Yaxuan Huang, Jun Li, Weiling Qin, Quanxiang Hao, Jiemei Ye, Zhe Zhang, Yushan Liang, Xue Xiao, Yonglin Cai

“…Finally, the lower mRNA and protein expression of RBL2 were validated in NPC cell lines and tissues. Conclusions Our ARGs-based signature model shows promising results in predicting the prognosis of NPC patients and might be associated with immune cell infiltration.…”
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Elucidating epigenetic landscape of gastric premalignant lesions through genome‐wide mapping of 5‐hydroxymethylcytosines: A 12‐year median follow‐up study by Zhongguang Luo, Wenshuai Li, Wanwei Zheng, Yixiang Shi, Maolin Ye, Xiangyu Guo, Kaiyi Fu, Changsheng Yan, Bowen Wang, Bin Lv, Shaocong Mo, Hongyang Zhang, Jun Zhang, Chuan He, Feifei Luo, Wei Zhang, Jie Liu

“…Results We identified 213 differentially modified gene bodies, primarily concentrated in pathways related to cell division, cell cycle, energy metabolism, inflammation and tumourigenesis. …”
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Rationale and design of APOLLO: a personalized rehAbilitation PrOgram in aLLOgeneic bone marrow transplantation by Edith Pituskin, Stephen Foulkes, Rachel J. Skow, Thomas McMurtry, Calvin Kruger, Janet E. Bates, Daena Lamoureux, Joseph Brandwein, Elena Lieuw, Cynthia Wu, Nancy Zhu, Peng Wang, Daniel Sawler, Minakshi Taparia, Marlene Hamilton, Tiffany Comfort-Riddle, Tara Meyer, Gabor T. Gyenes, Ian Paterson, Carla M. Prado, Mark J. Haykowsky, Justin G. Greiner, Margaret L. McNeely, Puneeta Tandon, Richard B. Thompson

“…Abstract Background Hematopoietic stem cell transplantation (HSCT) is a common therapy for many hematologic malignancies. …”
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Differentially expressed microRNAs in pre-transplant lung biopsies target immune checkpoint proteins and can predict primary graft dysfunction in lung transplantation by Vitale Miceli, Pia Ferrigno, Claudio Centi, Claudia Carcione, Gioacchin Iannolo, Valentina Agnese, Giovanna Lo Iacono, Rosa Liotta, Pier Giulio Conaldi, Massimo Pinzani, Lavinia De Monte, Alessandro Bertani

“…Although PGD is attributed to ischemia-reperfusion injury (IRI), immune responses, primarily T cell-mediated, may play a pivotal role in its pathogenesis. …”
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Proteomic and serologic assessments of responses to mRNA-1273 and BNT162b2 vaccines in human recipient sera by Thomas E. Hickey, Uma Mudunuri, Heidi A. Hempel, Troy J. Kemp, Nancy V. Roche, Keyur Talsania, Brian A. Sellers, James M. Cherry, Ligia A. Pinto

“…Thirty markers that contributed most to the model were associated with complement cascade and activation; IL-17, TNFR pro-apoptotic, and PI3K signaling; and cell cycle progression.DiscussionThese results demonstrate the utility of proteomics to evaluate correlates or predictors of serological responses to SARS-CoV-2 vaccination.…”
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Identification of common and specific fibrosis-related genes in three common chronic kidney diseases by Zhangning Fu, Xiaodong Geng, Chao Liu, Wanjun Shen, Zheyi Dong, Guannan Sun, Guangyan Cai, Xiangmei Chen, Quan Hong

“…Quantitative real-time PCR (qRT-PCR) was performed to validate the expression of the selected genes.Results Protein tyrosine phosphatase receptor type C (PTPRC), intercellular cell adhesion molecule-1 (ICAM1), vascular cell adhesion molecule-1 (VCAM1), interleukin 10 receptor alpha (IL10RA) and CC chemokine receptor 2 (CCR2) were identified as the potential common genes for kidney fibrosis in different types of CKD, while peroxisome proliferator-activated receptor alpha (PPARA), lactate oxidase (LOX), secreted phosphoprotein 1 (SPP1) were identified as the specific fibrosis-associated genes for DN, IgAN and MN respectively. qRT-PCR demonstrated that the expression levels of these selected genes were consistent with the NanoString analysis.Conclusions There were both commonalities and differences in the mechanisms of fibrosis in different types of CKD, the commonalities might be used as the common therapeutic targets for kidney fibrosis in CKD, while the differences might be used as the diagnostic markers for DN, IgAN and MN respectively. …”
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New evidence on the nephrotoxicity of fine particulate matter: Potential toxic components from different emission sources by Fu-Jen Cheng, Chien-Er Huang, Pei-Shih Chen, Yu-Lun Tseng, Chung-Shin Yuan, Ching-Shu Lai

“…PM2.5 water extracts from both sites induced inflammatory cytokine upregulation in the lungs and kidneys, and inflammatory cell infiltration, antioxidant activity downregulation, and elevated levels of kidney injury molecule 1 in the kidneys. …”
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Vitamin K‐dependent gamma‐carboxyglutamic acid protein 1 promotes pancreatic ductal adenocarcinoma progression through stabilizing oncoprotein KRAS and tyrosine kinase receptor EGF... by Zheng Wu, Qing Ye, Shan Zhang, Li‐Peng Hu, Xiao‐Qi Wang, Lin‐Li Yao, Lei Zhu, Shu‐Yu Xiao, Zong‐Hao Duan, Xue‐Li Zhang, Shu‐Heng Jiang, Zhi‐Gang Zhang, De‐Jun Liu, Dong‐Xue Li, Xiao‐Mei Yang

“…PRRG1 knockdown reduced PDAC cell proliferation, anchorage‐independent growth in vitro, and tumor growth in vivo. …”
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Peptide-based vaccine targeting IL17A attenuates experimental spondyloarthritis in HLA-B27 transgenic rats by Tetsuya Tomita, Hiromi Rakugi, Hiroki Hayashi, Ryuichi Morishita, Jiao Sun, Yuka Yanagida, Shota Yoshida, Satoshi Baba, Akiko Tenma, Masayoshi Toyoura, Sotaro Kawabata, Takako Ehara, Ryoko Asaki, Makoto Sakaguchi, Hideki Tomioka, Munehisa Shimamura, Hironori Nakagami

“…The ELISpot assay showed that the IL17A peptide-based vaccine did not elicit any IL17A-reactive T cell responses. IL17A vaccine tends to mitigate, but not significant, in SpA treatment model. …”
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Physicochemical and Textural Characterization of Perchlorated and Persulphated Titania by Nabawaya A. Moussa

“…ClO − 2 and S 2 O 2- 8 , resulted in an increase in the volume of the unit cell mainly due to an increase in the c 0 value of the tetragonal crystal lattice. …”
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The Influence and Legacy of the Shepherding Movement on the Current Neo-Pentecostal Movement in South Africa by Kelebogile T. Resane

“…These leaders aimed to provide meaning and order through house churches and cell groups to address the spiritual maturity of the Charismatic believers. …”
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Glutamine Supplementation in Sick Children: Is It Beneficial? by Elise Mok, Régis Hankard

“…This includes premature infants, infants with gastrointestinal disease, children with Crohn's disease, short bowel syndrome, malnutrition/diarrhea, cancer, severe burns/trauma, Duchenne muscular dystrophy, sickle cell anemia, cystic fibrosis, and type 1 diabetes. …”
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Advances in personalized gastroenterology and hepatology 2016 by E. Blum Hubert

“…Molecular and cell biology have resulted in major advances in our understanding of disease pathogenesis as well as in novel strategies for the diagnosis, therapy and prevention of human diseases. …”
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Formation and Evolution of Cellular Structures in Wedge-Induced Oblique Detonations by Chengxuan Yu, Zhenye Luan, Hua Jin, Yue Huang, Yancheng You

“…For the same degree of overdrive, numerical simulations reveal that the characteristic cell size of an oblique detonation is almost the same as that of a normal detonation.…”
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Heat Shock Proteins in Tendinopathy: Novel Molecular Regulators by Neal L. Millar, George A. C. Murrell

“…Heat shock proteins, also called damage-associated molecular patterns (DAMPs), are rapidly released following nonprogrammed cell death, are key effectors of the innate immune system, and critically restore homeostasis by promoting the reconstruction of the effected tissue. …”
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Unraveling the redox code to improve physiological research in human health and disease by Josh Thorley

“…While historically seen as harmful, ROS at low concentrations are now recognized as key regulators of cell signaling. A balance between ROS and antioxidants, known as redox balance, is crucial, and deviations can lead to oxidative stress. …”
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Perfluorocarbon Nanoparticles: Evolution of a Multimodality and Multifunctional Imaging Agent by Patrick M. Winter

“…In addition to these diagnostic imaging applications, the particles can be engineered to carry highly potent drugs and specifically deposit them into cell populations that display biosignatures of a variety of diseases. …”
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How to Quantify Nosema Spores Infection Rate in a Honey Bee Colony by Ashley N. Mortensen, Cameron Jack, Meghan McConnell, Liana Teigen, Jamie Ellis

“… Nosema are single-celled fungal parasites that infect various animal hosts. …”
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Modeling and Performance Analyses of Hybrid Cellular and Broadcasting Networks by Peter Unger, Thomas Kürner

“…The performance indicators cell load and grade of service are analyzed by using theoretical and realistic scenarios.…”
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