Novel ZAP-70-Related Immunodeficiency Presenting with Epstein–Barr Virus Lymphoproliferative Disorder and Hemophagocytic Lymphohistiocytosis by Moriah Forster, Timothy Moran, Anne Beaven, Timothy Voorhees

“…Zeta-chain-associated protein kinase 70 (ZAP-70) plays an integral role in the T-cell antigenic receptor complex. A deficiency of this kinase leads to a phenotype of severe combined immunodeficiency, while hypomorphic mutations of the kinase lead to more mild immunodeficiency phenotypes. …”
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Supramolecular Arrangement in Styphnic Acid and Naphthalene-1,4-diol (1 : 1) through a Novel Synthetic Rote for Styphnic Acid by Moamen S. Refat, Hossam A. Saad, Mohamed Y. El-Sayed, Abdel Majid A. Adam, Okan Zafer Yeşilel, Murat Taş

“…The compound crystallizes in the orthorhombic system in space group Pnma and cell parameters a=6.6712(2), b=16.8267(7), c=13.6450(5) Å and V=1531.71(10) Å3, and Z=4. …”
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Bilateral Gonadal Cysts and Late Diagnosis of Androgen Insensitivity Syndrome Treated by Laparoscopic Gonadectomy by D. Tourlakis, J. Schnabel, N. Fersis

“…A smaller cyst of the right adnexa revealed immature testis tissue with Leydig-cell hyperplasia. After karyotype and hormonal examinations, laparoscopic gonadectomy was performed. …”
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Clonal reproduction by seed of a cultivated hybrid plant: a new perspective for small-scale rice growers by Vernet, Aurore, Meynard, Donaldo, Guiderdoni, Emmanuel

“…Here, we have introduced synthetic apomixis in hybrid rice to produce a high (95–100%) frequency of clonal seeds, via the inactivation of three meiotic genes—resulting in unreduced, non-recombined gametes—and the addition of an egg cell parthenogenesis trigger. The genotype and phenotype, including grain quality, of the F1 hybrid are reproduced identically in the clonal apomictic progenies. …”
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New Insight for the Diagnosis of Gastrointestinal Acute Graft-versus-Host Disease by Florent Malard, Mohamad Mohty

“…Allogeneic stem cell transplantation (allo-SCT) is a curative therapy for different life-threatening malignant and nonmalignant hematologic disorders. …”
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Corneal crossed links: a new alternative in the treatment of ectasia by Maygret Alberro Hernández, Janet González Sotero, Haymy Caridad Casanueva Cabezas, Eduardo Rojas Álvarez

“…Density of endothelial cell and transparency of the cornea and crystallin remain unchanged. …”
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Identification of new ClpC1-NTD binders for Mycobacterium tuberculosis drug development by Katharina Weinhäupl, Louis Meuret, Sandy Desrat, Fanny Roussy, Nelly Morellet, Sandra Beaupierre, Catherine Guillou, Carine van Heijenoort, Olga Abian, Sonia Vega, Ian Wolf, Tatos Akopian, Olga Krandor, Eric Rubin, Adrian Velazquez-Campoy, Diego Gauto, Hugo Fraga

“…Recent studies have shown that several natural product antibiotics targeting the unfoldase N-terminal domain can impair MtbClpC1 function resulting in cell death. While the pharmacological properties of these natural product antibiotics prevent their use in the clinic, similar molecules binding to the same binding pockets can result in new drugs against Mtb. …”
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Flavonoid-membrane Interactions: A Protective Role of Flavonoids at the Membrane Surface? by Patricia I. Oteiza, Alejandra G. Erlejman, Sandra V. Verstraeten, Carl L. Keen, César G. Fraga

“…In this paper, we address the important, although not fully understood, capacity of flavonoids to interact with cell membranes. The interactions of polyphenols with bilayers include: (a) the partition of the more non-polar compounds in the hydrophobic interior of the membrane, and (b) the formation of hydrogen bonds between the polar head groups of lipids and the more hydrophilic flavonoids at the membrane interface. …”
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NIKOLAI KONSTANTINOVICH KOL’TSOV, THE AUTHOR OF THE TEMPLATE-DIRECTED SYNTHESIS CONCEPT AND FOUNDER OF EXPERIMENTAL BIOLOGY IN RUSSIA by N. N. Yurchenko, O. V. Trapezov, I. K. Zakharov

“…For four decades Koltsov was working on one major problem, cell organization. His studies were in line with trends in global biology. …”
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A New Case of dic(1;15)(p11;p11) in AML M1: Apropos of a Case and a Review of the Literature by Deniz Gören Şahin, Beyhan Durak, Eren Gündüz, Sevilhan Artan, Olga Meltem Akay

“…Acute myelogenous leukemia (AML) develops as the consequence of a series of genetic changes in a hematopoietic precursor cell. Specific cytogenetic abnormalities have been identified by karyotype analysis in AML. …”
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Macroscopic Model and Simulation Analysis of Air Traffic Flow in Airport Terminal Area by Honghai Zhang, Yan Xu, Lei Yang, Hao Liu

“…Methods in this work combine mathematical derivation and simulation analysis. Based on cell transmission model the macroscopic models of arrival and departure air traffic flow in terminal area are established. …”
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A Role for PPARβ/δ in Tumor Stroma and Tumorigenesis by Rolf Müller, Martin Kömhoff, Jeffrey M. Peters, Sabine Müller-Brüsselbach

“…Recent evidence suggests that stromal PPARβ/δ regulates tumor endothelial cell proliferation and promotes differentiation leading to the properly orchestrated events required for tumor blood vessel formation. …”
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Long non-coding RNA linc00152 acting as a promising oncogene in cancer progression by Danbi Seo, Dain Kim, Wanyeon Kim

“…Recently, linc00152 (an lncRNA) was identified as a potent oncogene in various cancer types, and shown to be involved in cancer cell proliferation, invasiveness, and motility by sponging tumor-suppressive microRNAs acting as a competing endogenous RNA, binding to gene promoters acting as a transcriptional regulator, and binding to functional proteins. …”
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Mitochondrial Dysfunction in Parkinson's Disease by P. C. Keane, M. Kurzawa, P. G. Blain, C. M. Morris

“…This paper aims to illustrate the considerable body of evidence linking mitochondrial dysfunction with neuronal cell death in the substantia nigra pars compacta (SNpc) of PD patients and to highlight the important need for further research in this area.…”
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Necrotizing Liver Granuloma/Abscess and Constrictive Aspergillosis Pericarditis with Central Nervous System Involvement: Different Remarkable Phenotypes in Different Chronic Granul... by Sanem Eren Akarcan, Neslihan Karaca, Guzide Aksu, Halil Bozkaya, Mehmet Fatih Ayik, Yasemin Ozdemir Sahan, Mehmet Arda Kilinc, Zafer Dokumcu, Cenk Eraslan, Emre Divarci, Hudaver Alper, Necil Kutukculer

“…The devastating course of disease regardless of the mutation emphasizes the importance of early diagnosis and intervention of hematopoietic stem cell transplantation as soon as possible in children with CGD.…”
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Inverse design of high-NA metalens for maskless lithography by Chung Haejun, Zhang Feng, Li Hao, Miller Owen D., Smith Henry I.

“…First, we derive a computational upper bound for a unit-cell-based axisymmetric metalens. Then, we demonstrate a fabrication-compatible inverse-designed metalens with 85.50% transmission normalized focusing efficiency at 0.6 numerical aperture at 405 nm wavelength; a higher efficiency than a theoretical gradient index lens design (79.98%). …”
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Overview of the evaluation of the destructive effect of procarbazine on the ovarian reserve in the apoptotic, inflammatory, and oxidative pathways by Kezban Kartlasmis, Ayse Nur Cakir Gungor, Yurdun Kuyucu, Samet Kara

“…Procarbazine has a detrimental impact on ovarian reserve by directly targeting the oocyte or indirectly through somatic cell destruction. Evidence gathered thus far indicates that procarbazine’s mode of action in the ovaries may involve apoptosis, inflammation, and oxidative stress. …”
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Hybrid Natural and Forced Active Balancing Control of Battery Packs State of Charge Based on Partnership for a New Generation of Vehicles by Yewen Wei, Shuailong Dai, Jiayu Wang, Zhifei Shan, Jie Min

“…Battery packs are widely used in electric vehicles, and their state-of-charge is one of the essential issues that affect the performances, whilst the balance between parallel and series cell of the battery pack always has an obvious effect. …”
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Synaptic Remodeling in the Dentate Gyrus, CA3, CA1, Subiculum, and Entorhinal Cortex of Mice: Effects of Deprived Rearing and Voluntary Running by Andrea T. U. Schaefers, Keren Grafen, Gertraud Teuchert-Noodt, York Winter

“…Hippocampal cell proliferation is strongly increased and synaptic turnover decreased after rearing under social and physical deprivation in gerbils (Meriones unguiculatus). …”
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Two-plasmon-decay instability stimulated by dual laser beams in inertial confinement fusion by C.-W. Lian, Y. Ji, R. Yan, J. Li, L.-F. Wang, Y.-K. Ding, J. Zheng

“…In this paper, TPD collectively driven by dual laser beams consisting of a normal-incidence laser beam (Beam-N) and a large-angle-incidence laser beam (Beam-L) is investigated via particle-in-cell simulations. It is found that significant TPD growth can develop in this regime at previously unexpected low laser intensities if the intensity of Beam-L exceeds the large-angle-incidence threshold. …”
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