Think twice: how single-cell suspensions from solid tissues for single-cell transcriptomics are well prepared by Meng-Meng Qu, Yan-Mei Jiao, Haijuan Wang

“…The preparation of a high-quality single-cell suspension from solid tissues is a critical step prior to single-cell RNA sequencing. …”
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APMAT analysis reveals the association between CD8 T cell receptors, cognate antigen, and T cell phenotype and persistence by Jingyi Xie, Daniel G. Chen, William Chour, Rachel H. Ng, Rongyu Zhang, Dan Yuan, Jongchan Choi, Michaela McKasson, Pamela Troisch, Brett Smith, Lesley Jones, Andrew Webster, Yusuf Rasheed, Sarah Li, Rick Edmark, Sunga Hong, Kim M. Murray, Jennifer K. Logue, Nicholas M. Franko, Christopher G. Lausted, Brian Piening, Heather Algren, Julie Wallick, Andrew T. Magis, Kino Watanabe, Phil Mease, Philip D. Greenberg, Helen Chu, Jason D. Goldman, Yapeng Su, James R. Heath

“…Abstract Elucidating the relationships between a class I peptide antigen, a CD8 T cell receptor (TCR) specific to that antigen, and the T cell phenotype that emerges following antigen stimulation, remains a mostly unsolved problem, largely due to the lack of large data sets that can be mined to resolve such relationships. …”
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Three-Dimensional Shapes and Cell Deformability of Rat Red Blood Cells during and after Asphyxial Cardiac Arrest by Hui Jai Lee, SangYun Lee, HyunJoo Park, YongKeun Park, Jonghwan Shin

“…In particular, rheological changes in red blood cells (RBCs) have been observed during and after ischemic-reperfusion injury. …”
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Breast Diffuse Large B-cell Lymphoma, Activated B-cell like Subtype: A Case Report by Sneha Samir Babaria, Jinalben Shaileshbhai Patel

“…Most PBL cases are of the B-cell type, accounting for up to 50% of all PBL. Diffuse Large B-cell Lymphoma (DLBCL) of the breast is a rare subtype of NHL, with a common age of presentation in females being 50-60 years. …”
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Genomics Analysis of Metabolic Pathways of Human Stem Cell-Derived Microglia-Like Cells and the Integrated Cortical Spheroids by Julie Bejoy, Xuegang Yuan, Liqing Song, Thien Hua, Richard Jeske, Sébastien Sart, Qing-Xiang Amy Sang, Yan Li

“…Stem Cells International…”
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Hyperoxia shows duration-dependent effects on the lengths of cell cycle phases in fetal cortical neural stem cells by Jennifer Lanto, Monika Maria Nicole Vehlken, Valeriia Abramenko, Alexander Storch, Alexander Storch, Franz Markert

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Different Chondrogenic Potential among Human Induced Pluripotent Stem Cells from Diverse Origin Primary Cells by Yeri Alice Rim, Yoojun Nam, Narae Park, Hyerin Jung, Yeonsue Jang, Jennifer Lee, Ji Hyeon Ju

“…Stem Cells International…”
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Identification of the Immune Cell Infiltration Landscape in Head and Neck Squamous Cell Carcinoma (HNSC) for the Exploration of Immunotherapy and Prognosis by Chunli Huang, Jifeng Liu

“…It is generally believed that the majority of head and neck cancers develop in the mucosal epithelial cells of the mouth, pharynx, and larynx, which is collectively known as head and neck squamous cell carcinoma (HNSC). …”
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Two Faces of Protein Kinase Cδ: The Contrasting Roles of PKCδ in Cell Survival and Cell Death by Alakananda Basu, Deepanwita Pal

“…Protein kinase Cδ (PKCδ) is a member of the PKC family that plays a critical role in the regulation of various cellular processes, including cell proliferation, cell death, and tumor promotion. …”
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Single-cell RNA-seq analysis reveals microenvironmental infiltration of myeloid cells and pancreatic prognostic markers in PDAC by Yanying Fan, Lili Wu, Xinyu Qiu, Han Shi, Longhang Wu, Juan Lin, Jie Lin, Tianhong Teng

“…Abstract Background Pancreatic ductal adenocarcinoma (PDAC) has a heterogeneous make-up of myeloid cells that influences the therapeutic response and prognosis. …”
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Osteopontin Expression in the Brain Triggers Localized Inflammation and Cell Death When Immune Cells Are Activated by Pertussis Toxin by Maria Cecilia Garibaldi Marcondes, Ryan Ojakian, Nikki Bortell, Claudia Flynn, Bruno Conti, Howard S. Fox

“…However, the role of OPN in inflammation is still controversial, since it can both prevent cell death and induce the migration of potentially damaging inflammatory cells. …”
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Patient-matched tumours, plasma, and cell lines reveal tumour microenvironment- and cell culture-specific microRNAs by Latasha Ludwig, Emma N. Vanderboon, Heather Treleaven, R. Darren Wood, Courtney R. Schott, Geoffrey A. Wood

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Correction: CD4 T cell contact drives macrophage cell cycle G0-G1 transition by Petra Mlcochova, Na Zhao, Omar Shabana, Roman Fischer, Ravindra K. Gupta

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IL-33 Protects Mice against DSS-Induced Chronic Colitis by Increasing Both Regulatory B Cell and Regulatory T Cell Responses as Well as Decreasing Th17 Cell Response by Jun-feng Zhu, Ying Xu, Jian Zhao, Xue Li, Xinrui Meng, Tian-qi Wang, Ben-yao Zou, Peng-yan Zhao, Qi Liu, Chang-long Lu, Fang-liang Zheng, Hong-sheng Liu

“…Previously, we have reported that IL-33 functioned as a protective modulator in dextran sulfate sodium- (DSS-) induced chronic colitis by suppressing Th17 cell response in colon lamina propria and IL-33 induced both regulatory B cells (Bregs) and regulatory T cells (Tregs) in mesenteric lymph nodes (MLNs) of mice with DSS-induced acute colitis. …”
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A Case Study in Process Improvement to Minimize Delays from Obtaining Blood for Red Cell Exchange for a Patient with Sickle Cell Disease and Multiple Red Blood Cell Alloantibodies by Damodaran Narayanan, Noreen B. Hogan, Karen A. Schaser, Patricia Ruegsegger, William Nicholas Rose

“…The process of procuring several units of red blood cells for red cell exchange can sometimes take several hours to days, especially for patients with multiple clinically significant red cell alloantibodies. …”
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Editorial: Community series in BCR signaling and B cell activation, volume 2 by Wenxia Song, Tae Jin Kim, Tae Jin Kim, Wanli Liu, Wanli Liu

Subjects: “…B cell…”
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Large-scale screening of HIV-1 T-cell epitopes restricted by 12 prevalent HLA-A allotypes in Northeast Asia and universal detection of HIV-1-specific CD8+ T cells by Yan Ding, Jialai Yan, Ling Huang, Jinhong Yu, Yandan Wu, Chuanlai Shen, Anning Fang

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Comparison of human-induced pluripotent stem cell-derived macrophages with peripheral blood-derived macrophages using single-cell genomics by ZHANG Yutong, HOU Guojun, SHEN Nan

Subjects: “…induced pluripotent stem cell (ipsc)…”
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PTEN suppresses renal cell carcinoma proliferation and migration via inhibition of the PI3K/AKT pathway by Xu Xu, Yuan-Yue Tang, Xiaohong Liang, Wen Luo, Dong-Mei Jiang, Jie Chen

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Primary central nervous system lymphoma: Comprehension of cell-of-origin subtypes by Shruti Rao, Sridhar Epari, Tanuja M. Shet, Sumeet Gujral, Hasmukh Jain, Bhausaheb Bagal, Manju Senagar, Prakash Shetty, Aliasgar Moiyadi, Jayant Sastri Goda, Tejpal Gupta

Subjects: “…activated b-cell…”
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