Serum and plasma as a good candidates of body fluids for detection lung cancer by FTIR liquid biopsy by Jolanta Smok-Kalwat, Stanisław Góźdź, Paweł Macek, Zuzanna Kalwat, Maryna Khalavka, Wioletta Rzad, Andrzej Stepulak, Joanna Depciuch

“…Abstract Using Fourier Transform Infrared spectroscopy (FTIR), it is possible to show chemical composition of materials and / or profile chemical changes occurring in tissues, cells, and body fluids during onset and progression of diseases. …”
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Construction of a Novel Necroptosis-Related Signature in Rat DRG for Neuropathic Pain by Liu Y, Hao S, Hao H, Zheng G, Bing J, Kang L, Li J, Zhao H, Hao H

“…Immune infiltration analysis revealed which types of immune cells related to the NRDEGs signature played an important role in the occurrence and development of neuropathic pain. …”
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Could Infectious Agents Play a Role in the Onset of Age-related Macular Degeneration? A Scoping Review by Petra P. Larsen, MD, PhD, Virginie Dinet, PhD, Cécile Delcourt, PhD, Catherine Helmer, MD, PhD, Morgane Linard, MD, PhD

“…Numerous potential pathophysiological mechanisms have been discussed, including (1) an indirect role of infectious agents (i.e. a role of infections located distant from the eye, mainly through their interactions with the immune system) and (2) a direct role of some infectious agents implying potential infection of various cells types within AMD-related tissues. Conclusions: Overall, this review highlights the diversity of possible interactions between infectious agents and AMD and suggests avenues of research to enrich the data currently available, which provide an insufficient level of evidence to conclude whether or not infectious agents are involved in this pathology. …”
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Étude des diarrhées en milieu périurbain à Abidjan par l’approche écosanté by Brama Koné, Mohamed Doumbia, Ibrahima Sy, Kouassi Dongo, Yveline Agbo-Houenou, Pascal Valentin Houenou, Benjamin Fayomi, Bassirou Bonfoh, Marcel Tanner, Guéladio Cissé

“…La tranche d’âge des moins de 5 ans était la plus affectée avec une prévalence de 14 %, suivie de celle des plus de 15 ans (6 %) et enfin des enfants de 5 à 15 ans (3 %).Les principaux facteurs de risques identifiés dans l’avènement des diarrhées sont, entre autres, le lieu de conservation de l’eau de boisson (P-value = 0,02), le récipient de conservation (p-value = 0,03) et le lieu d’installation des latrines dans les ménages (p-value = 0,02). …”
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Klasifikasi Alzheimer Berdasarkan Data Citra MRI Otak Menggunakan Fcm Dan Anfis by Nilna Almumtazah, Muhammad Sahrul Kiromi, Nurissaidah Ulinnuha

“…Abstract Alzheimer's disease is a neurological condition that gradually kills brain cells and can harm the brain permanently. About 50 million people worldwide have Alzheimer's disease or another kind of dementia. …”
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Genetic variation reveals the therapeutic potential of BRSK2 in idiopathic pulmonary fibrosis by Zhe Chen, Mingyang Tang, Nan Wang, Jiangjiang Liu, Xiaoyan Tan, Haitao Ma, Jing Luo, Kai Xie

“…Elevated BRSK2 expression in peripheral blood mononuclear cells correlated with reduced pulmonary function, while increased circulating BRSK2 levels suggested respiratory failure and shorter transplant-free survival in IPF patients. …”
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Comparative effects of different dietary pectin types on growth performance and intestinal health in pearl gentian grouper (Epinephelus fuscoguttatus♀ × E. lanceolatus♂) by Lulu Zhu, Xiaoxue Meng, Xuehan Wang, Jiongting Fan, Beiping Tan, Junming Deng

“…In conclusion, dietary 8 % ALP inclusion increased the relative abundance of beneficial bacteria in the intestine, enhanced the content of mucoprotein 2, suppressed intestinal inflammation, promoted tight junctions in intestinal cells, reduced intestinal permeability, and facilitated nutrient absorption, thereby supporting the growth of pearl gentian grouper, suggesting the potential of ALP as an additive for enhancing growth and gut health in marine fish.…”
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Amazonie vénézuélienne dans Voyage aux régions équinoxiales du Nouveau Continent (1799-1804) d'Alexandre de Humboldt : Nature et Homme  by Maurice Belrose

“…Tous les habitants sont soumis au même climat rude et débilitant, à la toute-puissance de la forêt équatoriale, mais celle-ci n'apparaît pas pour autant comme un « enfer vert ». …”
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Synthesis and characteristics of Fe/Ni/Cr oxide nanoparticles/PLA hybrid composite coatings on Mg–Zn–Ca alloy by Prakash Kumar, Aditya Kudva S, AnilKumar T, Ramesh S, M.R. Ramesh, Ashwini Prabhu, Gajanan Anne

“…Furthermore, cytocompatibility of the PLA hybrid composites on osteoblast cells and apoptosis detection using acridine orange-ethidium bromide. …”
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From Pioneering Discoveries to Innovative Therapies: A Journey Through the History and Advancements of Nanoparticles in Breast Cancer Treatment by Basingab FS, Alshahrani OA, Alansari IH, Almarghalani NA, Alshelali NH, Alsaiary AH, Alharbi N, Zaher KA

“…The advent of nanotechnology has introduced a new era characterized by the development of various nanoparticles, including liposomes, dendrimers, and gold nanoparticles, designed to target cancer cells with remarkable precision. We further described the mechanisms of action for nanoparticles, including passive and active targeting, and reviewed significant breakthroughs and clinical trials that have validated their efficacy. …”
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Aminoguanidine hemisulfate improves mitochondrial autophagy, oxidative stress, and muscle force in Duchenne muscular dystrophy via the AKT/FOXO1 pathway in mdx mice by Shiyue Sun, Tongtong Yu, Joo Young Huh, Yujie Cai, Somy Yoon, Hafiz Muhammad Ahmad Javaid

“…Additionally, AGH reduced apoptosis, shown by fewer TUNEL-positive cells and lower caspase-3 expression. Histological analysis revealed decreased muscle damage and fewer embryonic and neonatal myosin-expressing fibers. …”
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The activity of a herbal medicinal product of Phyllanthus niruri and Silybum marianum powdered extracts (Heptex®) in patients with apparent risk factors for nonalcoholic steatohepa... by Mohamed Kamal Shaker, Mohamed Hassany, Basem Eysa, AbdulMoneim Adel, Ahmed Zidan, Shahnaz Mohamed

“…Some medicinal plants have shown antioxidant and anti-inflammatory effects on liver cells. We aimed to investigate the hepatoprotective effect of Heptex® capsules containing 200 mg of Dukung Anak (a powdered extract from aerial parts of Phyllanthus niruri) and 100 mg of Milk Thistle (a powdered extract from fruits of Silybum marianum) in patients with an apparent risk factor for NASH. …”
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Advanced Glycation End Products Enhance Murine Monocyte Proliferation in Bone Marrow and Prime Them into an Inflammatory Phenotype through MAPK Signaling by Xian Jin, Liang Liu, Yaping Zhang, Yin Xiang, Guizhi Yin, Yi Lu, Ludong Shi, Jian Dong, Chengxing Shen

“…In vivo, AGEs (25 mg/kg i.p. for 7 days) increased proportions of CD115+ monocytes and the inflammatory subset, the CD115+Ly6Chigh cells, in murine bone marrow (flow cytometry analysis (FCM)), and enhanced gene expression of proinflammatory cytokines (IL-1β and TNF-α) but only slightly upregulated mRNA expression of anti-inflammatory cytokine (IL-10) (real-time PCR) in monocytes. …”
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Time to Reconsider the Straddle-Arm Technique: Providing Care for the Conscious Infant who is Choking

“…L'expérience personnelle des deux auteurs en matière de formation tend à démontrer que cette recommandation pourrait ne pas être physiquement réaliste dans un nombre important de cas en fonction des caractéristiques du sauveteur associées à celles du nourrisson. L'objectif de cet article est de présenter les résultats initiaux issus des travaux exploratoires visant à étayer ce point de vue et suggérant la nécessité de poursuivre les travaux afin d’améliorer le caractère universel de cette compétence. …”
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Lutein and inflammation: a comprehensive review of its mechanisms of action by Paradentavida Prathyusha, Geetha Viswanathan, Anjilikal Tomy Tomcy, Ponnamparambil P. Binitha, Smitha V. Bava, Edakkadath R. Sindhu

“…It reduces the risk of coronary artery disease and exerts anti-inflammatory effects on peripheral blood mononuclear cells (PBMCs). Lutein protects against alcohol-induced liver damage by modulating the nuclear factor erythroid 2-related factor 2 (Nrf2)/heme oxygenase-1 (HO-1) signaling pathway. …”
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Biopsy location and tumor-associated macrophages in predicting malignant glioma recurrence using an in-silico model by Pejman Shojaee, Edwin Weinholtz, Nadine S. Schaadt, Friedrich Feuerhake, Haralampos Hatzikirou

“…In particular, we introduced a state-of-the-art spatio-temporal model of tumor-immune interactions, emphasizing the interplay between macrophages and glioma cells. This model serves as a synthetic reality for assessing the predictive value of various features. …”
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ERK1/2 Inhibition Alleviates Diabetic Cardiomyopathy by Suppressing Fatty Acid Metabolism by Erin McLean, Caroline De Roo, Annabel Maag, Megan Coble, Jefferson Cano, Ruijie Liu

“…Methods: ERK1/2 phosphorylation in diabetes was determined both in vitro and in vivo. H9C2 cells were subjected to high glucose, high palmitic acid, or both high glucose and palmitic acid. db/db and streptozotocin (STZ)-induced diabetic mice were analyzed for ERK1/2 phosphorylation levels as well as the effects of U0126 treatment on cardiac remodeling. …”
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Zoning of the reaction of the tissues of the implantation area after prosthetic repair in abdominal hernias in experiment by E. E. Lukoyanychev, S. G. Izmailov, D. A. Evsyukov, V. O. Nikolskij, A. A. Mironov, A. V. Panyushkin

“…The zone adjacent to the implant, with a width of about 50 µm ("the zone of changes in adjacent tissues") significantly differs from the "zone of changes in distant tissues" by a more pronounced inflammatory reaction due to a larger absolute number of lymphocytes (р = 0.019 and fibroblasts (р = 0.017), giant cells of foreign bodies (р < 0.001), larger vascular area (р < 0.001) and extravasations (р = 0.002). …”
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Exploring survival rates in HIV-infected Ethiopian children receiving HAART: a retrospective cohort study by Yimam Getaneh, Yared Dejene, Birhanemeskel T. Adankie, Siti Qamariyah Khairunisa, Dominicus Husada, Kuntaman Kuntaman, Maria Inge Lusida

“…There was a high risk of mortality among female (adjusted HRs (AHRs) (95% CI) =1.35 (1.14 to 1.65)), those with poor adherence (AHR (95% CI) =1.29 (1.13 to 1.35)), CD4 count of ≤200 cells/mm3 (AHR (95% CI) =1.75 (1.33 to 2.30)) and baseline haemoglobin≤12 g/dL (AHR (95% CI) =1.8 (1.66 to 1.98)).Conclusion The significant drop in the survival rate as of the 6th year follow-up and the high loss rate to follow-up call for programme attention. …”
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miR-199a-5p Exacerbated Intestinal Barrier Dysfunction through Inhibiting Surfactant Protein D and Activating NF-κB Pathway in Sepsis by Xianjin Du, Dan Tian, Jie Wei, Chen Yan, Peng Hu, Xu Wu, Wenbin Yang, Zhanyong Zhu

“…Then, we proved that miR-199a-5p was induced in sepsis mice tissues and isolated intestinal epithelial cells. Moreover, miR-199a-5p increased D-lactic acid, DAO, and FD-40 while inhibition of miR-199a-5p exhibited a reversed process. …”
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