Pembrolizumab, radiotherapy, and an immunomodulatory five-drug cocktail in pretreated patients with persistent, recurrent, or metastatic cervical or endometrial carcinoma: Results... by Emiel A. De Jaeghere, Sandra Tuyaerts, An M. T. Van Nuffel, Ann Belmans, Kris Bogaerts, Regina Baiden-Amissah, Lien Lippens, Peter Vuylsteke, Stéphanie Henry, Xuan Bich Trinh, Peter A. van Dam, Sandrine Aspeslagh, Alex De Caluwé, Eline Naert, Diether Lambrechts, An Hendrix, Olivier De Wever, Koen K. Van de Vijver, Frédéric Amant, Katrien Vandecasteele, Hannelore G. Denys

“…Responders had a significantly higher proportion of peripheral T cells when compared to nonresponders (p = 0.013). …”
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The influencing factors of the erythropoietin resistance index and its association with all-cause mortality in maintenance hemodialysis patients by Xinju Zhao, Liangying Gan, Fan Fan Hou, Xinling Liang, Xiaonong Chen, Yuqing Chen, Zhaohui Ni, Li Zuo

“…Multivariate logistic regression showed that dialysis vintage (OR 0.957, 95% CI: 0.929–0.986), white blood cells (OR 0.900, 95% CI: 0.844–0.960), high flux dialyzer use (OR 0.866, 95% CI: 0.755–0.993), body mass index (OR 0.860, 95% CI: 0.828–0.892), males (OR 0.708, 95% CI: 0.625–0.801), and albumin (OR 0.512, 95% CI: 0.389–0.673) had a negative association with high ERI baseline (all p < 0.05). …”
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Gain-of-function ANXA11 mutation cause late-onset ALS with aberrant protein aggregation, neuroinflammation and autophagy impairment by Qing Liu, Ye Sun, Baodong He, Haodong Chen, Lijing Wang, Gaojie Wang, Kang Zhang, Ximeng Zhao, Xinzhe Zhang, Dongchao Shen, Xue Zhang, Liying Cui

“…Pathological analysis revealed early abnormal aggregates in spinal cord motor neurons, cortical neurons, and muscle cells of homozygous mice. From 2 months of age, we observed mislocalized ANXA11 aggregates, SQSTM1/p62-positive inclusions, and cytoplasmic TDP-43 mislocalization, which intensified with disease progression. …”
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Effects of Renal Denervation via Renal Artery Adventitial Cryoablation on Atrial Fibrillation and Cardiac Neural Remodeling by Wei Wang, Zhaolei Jiang, Rongxin Lu, Hao Liu, Nan Ma, Jie Cai, Min Tang, Ju Mei

“…LRDN significantly increased the percentage of TH-negative ganglionic cells and decreased the density of TH-positive nerves in the LSG (P<0.001). …”
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JinQi Jiangtang Tablet Regulates Gut Microbiota and Improve Insulin Sensitivity in Type 2 Diabetes Mice by Ying Cao, Guowang Yao, Yuanyuan Sheng, Li Yang, Zixuan Wang, Zhen Yang, Pengwei Zhuang, Yanjun Zhang

“…Gut mucosal barrier function experiment showed that the level of D-LA was obviously decreased in JQJT tablet-treated groups compared with the model group and the number of goblet cells was significantly increased by JQJT tablet treatment. …”
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Correlation between Neutrophil Gelatinase Associated with Lipocaline and Beta-2 Microglobulin with Other Renal Markers in Iraqi Patients with Multiple Myeloma by Inas Nazeeh Abed, Usama Salman Al-timari, Hiba Abid Al-Hussein hassan, Abbas Thamer Dwayyikh

“…The bone marrow is a spongy tissue in the middle of some bones that creates the body's blood cells. The current study is designed to find the correlation between Neutrophil gelatinase-associated lipocalin and ß2-Microglobulin with other renal markers among patients with multiple myeloma and healthy people. …”
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Effects of Fermented Pomegranate Peel Polyphenols on the Growth Performance, Immune Response, Hepatopancreatic Health, and Disease Resistance in White Shrimp (Litopenaeus vannamei) by Zhoulin Yu, Guangye Liu, Sijie Li, Yucong Hong, Shuyan Zhao, Meng Zhou, Xiaohong Tan

“…Additionally, increasing the addition level of FPPP resulted in a more compact hepatosomal arrangement of the shrimp’s hepatopancreas, a more visible star-shaped lumen structure, and a significantly higher number of B cells. Finally, the cumulative SR of shrimp in FPPP groups was significantly higher than that in FP0 group after 7 days of infection with Vibrio alginolyticus (p<0.05). …”
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Retinoprotective therapy of glaucoma by A.S. Makarova

“…</p> <p> <b>Keywords</b>: glaucoma, systemic blood pressure, peptide preparation, retinal ganglion cells, neuroprotection, retinoprotection. </p> <p> <b>For citation:</b> Makarova A.S. …”
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PKC及蛋白酪氨酸磷酸化信号通路对血管平滑肌细胞表型转化过程中容积调节性氯通道的作用

“…【目的】 比较蛋白激酶C (PKC)及蛋白酪氨酸磷酸化信号通路对大鼠股动脉平滑肌细胞(femoral artery smooth muscle cells, FASMC) 和股静脉平滑肌细胞(FVSMC)上容积调节性氯通道的调节作用的差异,同时观察这一调节作用在动静脉平滑肌细胞表型转化过程中的变化?…”
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Vaskulitis pada Lupus Eritematosus Sistemik by Zikry Aulia Hidayat, Raveinal Raveinal

“…In dermis underneath, was distributed inflammation cells perivascular, with lymphocyte and numerous PMN leukocyte. …”
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The growth and physiological responses of tambaqui Colossoma macropomum fed on the high dose of clove oil-supplemented diet by Andi Tiara Eka Diana Puteri, Dedi Jusadi, Sri Nuryati

“…The observation of fish liver histology showed that hepatocyte cells in the treatment of 100 mg clove oil become smaller and dense compared with 0 mg clove oil treatment. …”
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Comprehensive safety evaluation of isatuximab in multiple myeloma using disproportionality analysis of FAERS and meta-analysis of randomized controlled trials by Muhammed Favas Karimbanathottathil, Beema T Yoosuf, M Mamatha, Dipika Bansal

“…Abstract Isatuximab, an anti-CD38 monoclonal antibody, has been shown to induce apoptosis in multiple myeloma (MM) cells and is effective in both relapsed/refractory and newly diagnosed MM cases. …”
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Identification of Immune-Related lncRNA Pairs and Construction and Validation of a New Prognostic Signature of Colon Cancer by Minxian Xu, Qing Li, Jianfang Zhang, Hui Xie

“…Then, the signature was evaluated by clinicopathological features, tumor-infiltrating immune cells, checkpoint-related biomarkers, targeted therapy, and chemotherapy. …”
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Gastrointestinal absorption and its regulation of hawthorn leaves flavonoids by Junwei Chow, Xiaolei Yang, Jiarong Hu, Qiuxia Yu, Yu Zhong, Xinyi Hu, Jingru Liang, Chenyang Zhu, Shiwei Yan, Longzhou Li, Haiyang Liu, Tiandian Wang, Zihan Wang, Long Gao, Guo Ma

“…Apparent permeability coefficient (P app) of five flavonoids were (2.18 ± 0.15) ×10−7~(3.83 ± 0.22) ×10−7 cm·sec−1 across the Caco-2 cells. GLV, RHV, VIT and RUT demonstrated similar and poor absorption in rat stomach (absorption percentage per hour (A), (1.78 ± 0.14 ~ 5.69 ± 0.51)%·h−1) and small intestine (absorption rate ( $$\:{k}_{a}^{app}$$ , (0.012 ± 0.006 ~ 0.055 ± 0.003) h−1), extent (A, (1.28 ± 0.14 ~ 2.82 ± 0.19)% ·h−1) and potential (P app, (0.31 ± 0.05 ~ 1.41 ± 0.08)×10−7 cm·sec−1)), while HP showed relatively better absorption (P app, (2.55 ± 0.15 ~ 4.27 ± 0.36)×10−7 cm·sec−1) in rat small intestine. …”
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In-Situ Electrospinning Dressings Loaded with Kaempferol for Reducing MMP9 to Promote Diabetic Ulcer Healing by Li J, Meng H, Guo W, Zhou L, Wu S, Gao G, Liu Q, You D, Qu W

“…Then, the in vitro biocompatibility of the dressings was evaluated using NIH3T3 cells. The in vivo wound healing efficacy of the dressings was analyzed in the diabetic wound model rats. …”
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Role of Inhibin B and Ratio of Luteinizing: Follicle-Stimulating Hormones in Phenotyping Polycystic Ovarian Syndrome by Zainab G. Falh, Basil O. Saleh, Afraa M. Al Naddawi, Ghada Mohammed

“… Background: Polycystic ovary syndrome is among the leading causes of fertility-related problems and menstrual irregularities in women of reproductive age. The granulosa cells of the developing pre-antral and antral follicles produce inhibin B, which triggers chemical responses in the ovaries. …”
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Association of CSF soluble TREM1 levels with hippocampal atrophy in cognitively impaired older adults by Hao Shu, Gangyu Ding, Xiaona Xu, Xuerong Huang, Ruqian He

“…BackgroundRecent studies have shown that cerebrospinal fluid (CSF) levels of soluble triggering receptor expressed on myeloid cells 1 (sTREM1) are elevated in individuals with Alzheimer’s disease (AD), though the relationship between CSF sTREM1 and hippocampal atrophy remains to be elucidated. …”
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Rice blast incidence and morphological variation of Magnaporthe oryzae, Cav. in Ebonyi State, Nigeria by Buliaminu Adeniyi Yekini, Olaitan Chinenye Okechukwu, Clement Gboyega Afolabi

“…The twenty-two isolates, identified as Magnaporthe oryzae (Mo), grown on potato dextrose agar showed various differences in their cultural and morphological characters such as colony colour, margin, pigmentation, surface texture, shapes, septate and cells. Pathogenicity study revealed the five isolates Mo-03, Mo-05, Mo-06, Mo-10 and Mo-17 where more virulent than others. …”
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Systematic review on the compliance of WHO guidelines in the management of patients with advanced HIV disease in Africa: The case of cryptococcal antigen screening. by Zuhura Mbwana Ally, Jackline Vicent Mbishi, Mariam Salim Mbwana, Hafidha Mhando Bakari, Swalehe Mustafa Salim, Zarin Nudar Rodoshi, Muhidin Ibrahim Hundisa, Rebecca Mesfin Sileshi, Biruk Demisse Ayalew, Rahma Musoke, Lynn Moshi, Yousef Elias Fakhoury, Haji Mbwana Ally, Habib Omari Ramadhani

“…CrAg uptake was defined as percentage of eligible people (CD4 ≤ 200 cells/mm3 or WHO stage III/IV) who received cryptococcal antigen testing. …”
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Effects of dietary bile acid on the growth performance, intestinal health, blood biochemistry, and antioxidative response of Nile tilapia (Oreochromus niloticus) fed high-fat diets by Mahmoud A.O. Dawood, Sameh El-Dahan, Samy Elsaadawy, Ahmed E. Noreldin, Hani Sewilam

“…The HF diet without BA supplementation revealed massive hepatic steatosis pancreatic vascular congestion and a high necrotic pancreatic cells number. While supplementing BA in HF diets enhanced pancreatic architecture and decreased necrotic hepatocytes. …”
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