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29761
Graphene-Based Materials for Bone Regeneration in Dentistry: A Systematic Review of In Vitro Applications and Material Comparisons
Published 2025-01-01“…Studies have revealed that the presence of graphene can stimulate the proliferation and differentiation of bone cells, thereby promoting the formation of new bone tissue. …”
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29762
Exploring the association between statins use or HMG-CoA reductase inhibition and migraine: a systematic review and meta-analysis
Published 2025-02-01“…Abstract Background Statins or 3‑hydroxy‑3‑methyl‑glutarylcoenzyme A (HMG‑CoA) reductase inhibitors are medications that act by reducing the cholesterol content of liver cells Moreover, statins have been found to improve endothelial function and reduce vascular wall inflammation. …”
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29763
Classification of Nanomaterial Drug Delivery Systems for Inflammatory Bowel Disease
Published 2025-02-01“…In summary, NDDS enhance the targeted delivery of therapeutic agents to specific cells or tissues, thereby improving drug bioavailability and therapeutic efficacy. …”
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29764
A Peptide Analogue of Selectin Ligands Attenuated Atherosclerosis by Inhibiting Monocyte Activation
Published 2019-01-01“…In this study, we firstly measured the effect of the IELLQAR selectin-binding peptide on the inhibition of binding of selectins to monocytes by flow cytometry, which exhibited a dose-dependent inhibitory effect on the binding of the P-, E-, and L-selectins to monocytes, especially the inhibition of P-selectin binding to human peripheral blood monocytes (PBMCs) (half maximal inhibitory concentration (IC50~5 μM)) and THP-1 cells (IC50~10 μM). Furthermore, IELLQAR inhibited P-selectin-induced activation of CD11b on the surface of monocytes and decreased adhesion of monocytes to the endothelium. …”
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29765
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29766
De quelques enjeux de Rio+20
Published 2012-01-01“…Comment imaginer, alors que les objectifs du Millenium sont loin d’être atteints, que tous ceux qui sont victimes, ici et maintenant, des pires maux qui frappent la planète accepteront facilement que soient « détournés » ces moyens au bénéfice de générations futures, alors que la question qu’ils affrontent est celle de leur survie au quotidien. Vouloir les associer au sauvetage du climat sans satisfaire dès à présent leurs besoins pressants les plus essentiels ne saurait conduire qu’à l’impasse. »Cette question se pose aussi en terme éthique et sous le large vocable de l’adaptation, terme à la mode, tout comme celui de la résilience, actuellement en sciences de l’environnement. …”
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29767
Structural Characterization and Antioxidant Activity in Vivo of Polysaccharides from the Leaves of Hippophae rhamnoides L.
Published 2025-02-01“…The HE staining results indicated that HRLP had protective effect on liver and kidney tissue cells and structure damage in mice. The medium dose group of HRLP could increase the number of gut microbiota species in mice and promote the synthesis of short-chain fatty acids in the body. …”
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29768
Effects of Massive Transfusion Protocol Implementation in Trauma Patients at a Level I Trauma Center
Published 2020-06-01“…Methods From January 2016 to September 2019, the medical records of trauma patients who received at least 10 units of packed red blood cells (PRBC) at Pusan National University Hospital (level I trauma center) were retrospectively reviewed. …”
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29769
Evaluation of maSSS/maSES-PEG2-RM26 for their potential therapeutic use after labeling with Re-188. Could their [99mTc]Tc-labeled counterparts be used to estimate dosimetry?
Published 2025-01-01“…In GRPR expressing PC-3 cells, both [188Re]Re-labeled peptides displayed high cellular uptake (8.5 ± 0.1% and 5 ± 0.3% of added activity, respectively), heavily GRPR-driven, while retaining the radioantagonistic profile with slow internalization rates. …”
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29770
Effect of ethanol extract of nigella sativa L seeds and propofol on BDNF protein level as neuroplasticity and neuroprotection of traumatic brain injury in rats [version 2; peer rev...
Published 2024-09-01“…Nigella Sativa L had a better effect than propofol in repairing damaged neuron cells (neuroplasticity) and increasing BDNF protein levels (neuroprotection) for 7 days of administration in rat traumatic brain injury.…”
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29771
The transcription factor dFOXO controls the expression of insulin pathway genes and lipids content under heat stress in <i>Drosophila melanogaster</i>
Published 2021-09-01“…To identify the properties of interaction of two key IIS pathway components under heat stress in D. melanogaster (the forkhead box O transcription factor (dFOXO) and insulin-like peptide 6 (DILP6), which intermediates the dFOXO signal sent from the fat body to the insulin-producing cells of the brain where DILPs1–5 are synthesized), we analysed the expression of the genes dilp6, dfoxo and insulin-like receptor gene (dInR) in females of strains carrying the hypomorphic mutation dilp641 and hypofunctional mutation foxoBG01018. …”
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29772
Financial and non–financial factors in companies’ adaptation process towards sustainability and sustainable business models
Published 2023-01-01“…The study analyzed 6,864 observations, that is, 96,096 data cells. The data are divided into two groups of variables: financial and non-financial. …”
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29773
A new hybrid distance and similarity based scenario reduction approach for stochastic economic operation of microgrid
Published 2025-03-01“…This stochastic model is aimed at generating the optimum schedules for various dispatchable generating resources such as micro-turbines, fuel cells, utility grid, energy storage devices as per the availability of the various VRE resources to meet the uncertain demand for a day-to-day microgrid operation. …”
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29774
In vitro antiplasmodial activity of six plants against chloroquine-sensitive and resistant strains of Plasmodium falciparum
Published 2025-01-01“…ects (CC50) of the plant extracts against red blood cells were evaluated using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) rapid calorimetric assay technique. …”
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29775
Histopathologic Outcomes of Robotic Radical Prostatectomy
Published 2006-01-01“…A positive margin was reported if cancer cells were found at the inked specimen margin. PSA data were collected every 3 months for the first year, then every 6 months for a year, then yearly. …”
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29776
Assessing the feasibility of using publicly available data sources to identify healthcare data discrepancies and enhance service delivery: a retrospective cross-sectional study of...
Published 2024-04-01“…Criteria for our retrospective cross-sectional study included a LHDIS and recent availability of both DHS and SPA data for data relevance.Results The approach was feasible, with relevant indicators distributed across various QoC categories. However, some cells in the indicator matrix lacked suitable indicators from SPA and DHS data. …”
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29777
Cryptolepine, the Main Alkaloid of the Antimalarial Cryptolepis sanguinolenta (Lindl.) Schlechter, Induces Malformations in Zebrafish Embryos
Published 2019-01-01“…Previous studies on cryptolepine, the antimalarial and cytotoxic alkaloid of Cryptolepis sanguinolenta, showed that it preferentially accumulates in rapidly proliferating cells and melanin-containing tissues. Subsequently, we demonstrated that cryptolepine was toxic to murine embryos in vivo but no signs of teratogenicity. in vivo developmental studies can be confounded by maternal effects. …”
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29778
ANALYSIS OF GENETIC CHARACTERISTICS OF INFLUENZA VIRUS A/CHICKEN/CHELYABINSK/30/2019 H9N2 ISOLATED IN CHELYABINSK OBLAST
Published 2019-12-01“…Most amino acid positions of hemagglutinin (according to H3 subtype sequence numbering) suggest affi nity for the ACA2-3Gal-receptors of avian epithelial cells. Amino acid substitutions were detected at the site within the receptor-binding domain as compared to the A/H9N2 infl uenza virus isolates obtained in Russia in 2018. …”
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29779
Effects of cardiac contractility modulation on autophagy and apoptosis of cardiac myocytes in rabbits with chronic heart failure.
Published 2024-01-01“…The apoptosis rate and the apoptosis of myocardial cells was observed by flow cytometry and TUNEL method.…”
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29780
Interpretable machine learning models for predicting skip metastasis in cN0 papillary thyroid cancer based on clinicopathological and elastography radiomics features
Published 2025-01-01“…BackgroundSkip lymph node metastasis (SLNM) in papillary thyroid cancer (PTC) involves cancer cells bypassing central nodes to directly metastasize to lateral nodes, often undetected by standard preoperative ultrasonography. …”
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