Fish-derived hepcidins in cancer treatment: a scoping review by Wan-Atirah Azemin, Syarifah Ab Rashid, Noraini Philip, Abdul Manaf Ali, Mohd Shahir Shamsir

“…Tilapia-derived hepcidins demonstrated notable anticancer properties, including concentration-dependent effects, selective cytotoxicity against cancer cells, and potential enhancement of conventional chemotherapy efficacy through mechanisms involving reactive oxygen species production and mitochondrial apoptosis pathways. …”
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Neuraminidase-mediated enhancement of Streptococcus pneumoniae colonization is associated with altered mucus characteristics and distribution by Matthew T. Montgomery, Mila Ortigoza, Cynthia Loomis, Jeffrey N. Weiser

“…Mucus exposed to NA showed increased localization within goblet cells and lining the glycocalyx. By contrast, NA-naïve mucus was more likely to be observed sloughing away from the epithelial surface. …”
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Tissue-specific effects of benzo[a]pyrene and DDT on microRNA expression profile in female rats by D. S. Ushakov, T. S. Kalinina, A. S. Dorozhkova, V. Y. Ovchinnikov, L. F. Gulyaeva

“…In part, such disorders can be mediated by the activation of nuclear receptors, resulting in the activation of protein coding gene expression and microRNAs involved in malignant transformation of cells. Therefore, the aim of this study was to investigate the chain of events “xenobiotic administration – receptor activation – up-regulating microRNA expression – down-regulation target genes expression” as one of the key factors in the chemically-induced carcinogenesis. …”
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Separable roles of the DNA damage response kinase Mec1ATR and its activator Rad24RAD17 during meiotic recombination. by Margaret R Crawford, Jon A Harper, Tim J Cooper, Marie-Claude Marsolier-Kergoat, Bertrand Llorente, Matthew J Neale

“…Despite these differences, complex multi-chromatid events initiated by closely spaced DSBs-rare in wild-type cells-occur more frequently in the absence of either Rad24 or Mec1, suggesting a loss of spatial regulation at the level of DSB formation in both. …”
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Analyzing exosomal miRNA profiles in tetralogy of fallot fetuses’ amniotic fluid by Hainan Yang, Yadan Li, Qiuyue Chen, Shangqing Li, Yiru Yang, Guorong Lyu

“…Further investigation using mouse embryonal carcinoma P19 cells revealed that miR-10a-5p overexpression inhibited cardiomyogenic differentiation, as evidenced by the suppression of cardiomyocyte marker genes like TBX5. …”
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Molecular genetic basis of epidermolysis bullosa by Yu. Yu. Kotalevskaya, V. A. Stepanov

“…Genetic mutations cause dysfunction of cellular structures, differentiation, proliferation and apoptosis of cells, leading to mechanical instability of the skin. …”
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Exosomes and microRNAs as mediators of the exercise by Haoyuan Li, Guifang Liu, Bing Wang, Mohammad Reza Momeni

“…These molecules play main roles in important processes such as the growth of skeletal muscle and heart muscle cells, the creation of mitochondria, the development of the vascular system, and the regulation of metabolism. …”
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Effects of organic amendment on some soil physicochemical characteristics and vegetative properties of Zea mays in wetland soils of the Niger Delta impacted with crude oil by Francis E. Egobueze, Josiah M. Ayotamuno, Chukwujindu M. A. Iwegbue, Chibogwu Eze, Reuben N. Okparanma

“…For each soil type, 48 treatment cells and 1 control containing 1 kg of soil each were spiked with crude oil at concentrations ranging from 50 to 200 g kgâ1, representing 5â20% (m/m) contamination levels, respectively. …”
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High-intensity focused ultrasound: an innovative approach for micro-manipulation of demineralized dentine by Sheetal Maria Rajan, Barsha Shrestha, Amr Fawzy

“…Furthermore, HIFU promoted the proliferation of dental pulp stem cells (n = 3/group) while maintaining the associated temperature-rise within the physiological tolerance. …”
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Identification and characterization of CONSTANS-like (COL) gene family in upland cotton (Gossypium hirsutum L.). by Darun Cai, Hui Liu, Na Sang, Xianzhong Huang

“…Tissue-specific expression showed that 42 GhCOL genes may function as tissue-specific regulators in different cells or organs. We cloned and sequenced the 14 GhCOL genes in Group I related to flowering induction to study their diurnal expression pattern, and found that their expression showed distinct circadian regulation. …”
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Transcriptional induction of the IMD signaling pathway and associated antibacterial activity in the digestive tract of cat fleas (Ctenocephalides felis) by Katie Weber, Dhruva Karnik, Lisa D. Brown

“…To combat foodborne illness, insect midgut epithelial cells are armed with efficient microbial recognition and control systems, such as the immune deficiency (IMD) pathway that regulates the expression of antimicrobial peptides (AMPs). …”
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A rare case of double pituitary prolactinomas: the diagnostic application of intraoperative ultrasonography and DNA methylation markers by Jared C. Reese, Thomas M. Zervos, Jack Rock, Abeer Tabbarah, Houtan Noushmehr, Grayson Herrgott, Ana Valeria Castro

“…In tissue specimens, PT-specific markers distinguished T1 from NT tissue, while T2, primarily nontumor cells, clustered with NT specimens. In liquid biopsies, these markers differentiated between T and NT cohorts. …”
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A review on mechanisms of action of bioactive peptides against glucose intolerance and insulin resistance by Forough Jahandideh, Jianping Wu

“…The recent discoveries of pathways and target cells in the management of glucose and energy metabolism have opened up new opportunities for identification of novel bioactive peptides on enhancing adipocyte differentiation and insulin signaling, glucose uptake, cholecystokinin receptor expression and activation, as well as insulin mimetics and incretin stimulants. …”
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Glucose-6-phosphate dehydrogenase deficiency with coinherited Gaucher disease: A rare association by Nupur Parakh, Kusha Sharma, Sunita Sharma, Priti Chatterjee, Varinder Singh

“…Peripheral smear showed predominantly microcytic hypochromic anemia with moderate degree of anisocytosis, many nucleated red blood cells, few schistocytes, polychromatophils and corrected reticulocyte count 7.89%. …”
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Proteomic characterization of molecular mechanisms of paraquat-induced lung injury in a mouse model by Yu Qing Zhou, Jin Jin Peng, Li Ping Shan, Wei Liu

“…Conclusions PQ-induced ALI depends on over-activation of immune responses by damaged alveolar/endothelial cells, and the complement/coagulation cascade pathway plays a key role during this process. …”
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MicroRNA-221 protects myocardial contractility in myocardial ischemia/reperfusion injury through phospholamban. by Hongyu Li, Jimiao Qiu, Chang Liu, Guobing Yu, Danyu Wu, Yichun Chu, Kai Wang

“…Changes in the structural integrity of the mouse heart were identified with HE and MASSON staining, while TUNEL staining was used to evaluate the TUNEL-positive cells of cardiomyocytes. Changes in myocardium calcium concentration were detected with reagent kits and the targeting interaction between miRNA 221 and PLB was evaluated using a luciferase reporter assay.…”
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Extracellular CIRP Upregulates Proinflammatory Cytokine Expression via the NF-kappaB and ERK1/2 Signaling Pathways in Psoriatic Keratinocytes by Xiu Zhang, Shengbang Wang, Wei Wang, Liumei Song, Shuo Feng, Jingping Wang, Tong Kang, Peiwen Yang, Ning Wang, Pengju Yang, Ruimin Bai, Yongping Shao, Yan Zheng

“…Our data show that eCIRP expression was increased in the sera of psoriasis patients and imiquimod- (IMQ-) induced psoriatic mice and cells stimulated with proinflammatory cytokines (IL-1α, IL-17A, IL-22, oncostatin M, and TNF-α; mix M5). …”
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Two Cases of Severe Hypertension in JAK2 Mutation-Positive Myeloproliferative Neoplasms by Raunak Rao, Spoorthy Kulkarni, Ian B. Wilkinson

“…Myeloproliferative neoplasms are a heterogeneous group of disorders resulting from the abnormal proliferation of one or more terminal myeloid cells—established complications include thrombosis and haemorrhagic events; however, there is limited evidence to suggest an association with arterial hypertension. …”
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Exosome-Associated Gene Signature for Predicting the Prognosis of Ovarian Cancer Patients by Zihan Zhu, Rui Geng, Yixin Zhang, Jinhui Liu, Jianling Bai

“…We discovered that resting dendritic cells and stromal scores were upregulated in patients with high risk in the TCGA and Gene Expression Omnibus (GEO) cohorts. …”
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Essential Factors in Predicting the Need for Angio-Embolization in the Acute Treatment of Pelvic Fracture with Hemorrhage by Seok-Won Yang, Hee-Gon Park, Sung-Hyun Kim, Sung-Hyun Yoon, Seung-Gwan Park

“…Patient variables included sex, initial hemoglobin concentration, initial systolic blood pressure, transfused packed red blood cells within 24 hours, Injury Severity Score (ISS), mortality rate, length of hospital stay, and time to angio-embolization. …”
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