Anti-Biofilm Effect of Ampicillin-Loaded Poly (Lactic-co-glycolic Acid) Nanoparticles Conjugated with Lysostaphin on Methicillin-Resistant Staphylococcus aureus by Elahe Norouzi, Seyed Mostafa Hosseini, Babak Asghari, Reza Mahjoub, Ehsan Nazarzadeh Zare, Mohammad-Ali Shahbazi, Fereshte Kalhori, Mohammad Reza Arabestani

“…The toxicity test findings revealed that the synthesized nanodrug had no toxic effects on the cells. Given the excellent efficacy of the nanomedicine carrier established in the present study, applying this technology to combat hospital-acquired infections caused by Staphylococcus bacteria could yield significant benefits in managing staphylococcal infections.…”
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Deficiency of MicroRNA-23-27-24 Clusters Exhibits the Impairment of Myelination in the Central Nervous System by Yuji Tsuchikawa, Naosuke Kamei, Yohei Sanada, Toshio Nakamae, Takahiro Harada, Kazunori Imaizumi, Takayuki Akimoto, Shigeru Miyaki, Nobuo Adachi

“…Although differentiation of oligodendrocyte progenitor cells to oligodendrocytes was not inhibited in the knockout mice, the percentage of oligodendrocytes expressing myelin basic protein was significantly lower in 4-week-old knockout mice than that in wild-type mice. …”
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The subcompartmented oxphosomic model of the phosphorylating system organization in mitochondria by I. V. Ukolova

“…The oxidative phosphorylation (OXPHOS) system of mitochondria supports all the vitally important energyconsuming processes in eukaryotic cells, providing them with energy in the form of ATP. …”
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TiO2 Nanocoatings with Controllable Crystal Type and Nanoscale Topography on Zirconia Implants to Accelerate Bone Formation by Nan Li, Zhichao Liu, Guanqi Liu, Zhi Wang, Xianwei Guo, Chuanbin Guo, Jianmin Han

“…In addition, in vitro cytocompatibility and osteogenic potential performance of the coatings were evaluated by human bone marrow mesenchymal stem cells (hBMSCs), and in vivo osseointegration performance was assessed in a rat femoral condyle model. …”
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Lipotoxicity and metabolic disorders at obesity by V. T. Ivashkin, M. V. Mayevskaya

“…In this aspect it is necessary to focus on glitazones (PPARs ligands), metformin among pharmacological substances, which has no influence on insulin secretion, however it has a lot of extrapancreatic effects by which it reduces increased concentrations of glucose in blood, improves tissue sensitivity to insulin and, thus, increases uptake of glucose by liver and muscles cells. In 2009 results of clinical and experimental researches which show significant efficacy of ursodeoxycholic acid at a dose of 30 mg/kg in treatment of non-alcoholic steatohepatitis and major therapeutic potential of silibinin and silibinin/phosphatidylcholine complex at non-alcoholic fatty liver disease were submitted.…”
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Neuroprotective Effects of Collagen-Glycosaminoglycan Matrix Implantation following Surgical Brain Injury by Jia-Hui Chen, Wei-Cherng Hsu, Kuo-Feng Huang, Chih-Huang Hung

“…Proinflammatory (tumor necrosis factor-alpha (TNF-α), interleukin-6 (IL-6), and NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells)) and anti-inflammatory (IL-10 and granulocyte-macrophage colony-stimulating factor (GMCSF)) cytokine expression was evaluated by enzyme-linked immunosorbent assays. …”
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Interference in Macrophage Balance (M1/M2): The Mechanism of Action Responsible for the Anti-Inflammatory Effect of a Fluorophenyl-Substituted Imidazole by Julia Salvan da Rosa, Eduarda Talita Bramorski Mohr, Tainá Larissa Lubschinski, Guilherme Nicácio Vieira, Thais Andreia Rossa, Marcus Mandolesi Sá, Eduardo Monguilhott Dalmarco

“…Recently, an alternative has been presented by researchers to solve this problem: The immunomodulation of cells closely related to inflammation. Hence, macrophages, a critical key in both innate and acquired immunity, have been presented as an alternative target for the development of new medicines. …”
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Anatomy, ploidy level, and essential oil composition of <i>Hyssopus officinalis</i> ʻNikitskiy Beliyʼ <i>in vitro</i> and <i>ex situ</i> by I. V. Bulavin, N. N. Ivanova, N. N. Miroshnichenko, N. M. Saplev, S. A. Feskov

“…The analysis of the ploidy level and relative DNA content in the nuclei isolated from the leaf tissue cells of the microshoots ex vitro after adaptation revealed no changes compared to the ex situ leaf parameters. …”
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Enzyme-Aided Treatment of Fruit Juice: A Review by Liew Phing Pui, Lejaniya Abdul Kalam Saleena

“…Enzymatic treatment is a common method of fruit juice production that facilitates juice extraction from plant cells. The choice of enzyme depends on the fruit composition. …”
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Multiple Primary Angiosarcomas of the Colon by Sonja Radić, Mario Zovak, Anita Galović Marić, Stjepan Baturina, Monica Stephany Kirigin, Božo Krušlin

“…Microscopically, the tumors were composed of solid sheets of spindle and epithelioid neoplastic cells with prominent nucleoli and numerous mitotic figures and immunohistochemically positive for ERG, CD31, CD34, vimentin, and CD117, while negative for CK7, CK20, CD20, CD3, CD45, TTF-1, PAN-CK, ALK, Mpox, S-100, and DOG1, leading to the final diagnosis of multiple colonic angiosarcomas. …”
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Salivary Fractalkine Differentiating Periodontitis from Periodontally Healthy Subjects by Omer Mohammed Harbood, Raghad Fadhil Abbas

“…Accordingly, the proliferation, adhesion, and migration of inflammatory cells are all affected by it. In light of this, the present study attempts to address the following questions: (1) Is the salivary level of fractalkine and its receptor associated with periodontitis patients with different severities? …”
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La bibliothèque dans Le Silence de la mer, un espace symbolique by Nathalie Gibert-Joly

“…Si on ne l’a pas lu, on en connaît du moins l’histoire, celle d’un officier allemand Werner von Ebrennac qu’un oncle et sa nièce sont obligés d’accueillir dans leur maison. …”
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Leucine Modulates Mitochondrial Biogenesis and SIRT1-AMPK Signaling in C2C12 Myotubes by Chunzi Liang, Benjamin J. Curry, Patricia L. Brown, Michael B. Zemel

“…Previous studies from this laboratory demonstrate that dietary leucine protects against high fat diet-induced mitochondrial impairments and stimulates mitochondrial biogenesis and energy partitioning from adipocytes to muscle cells through SIRT1-mediated mechanisms. Moreover, β-hydroxy-β-methyl butyrate (HMB), a metabolite of leucine, has been reported to activate AMPK synergistically with resveratrol in C2C12 myotubes. …”
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Exercise promotes peripheral glycolysis in skeletal muscle through miR-204 induction via the HIF-1α pathway by Sang R. Lee, Kang Joo Jeong, Moeka Mukae, Jinhee Lee, Eui-Ju Hong

“…Treatment with a miR-204 mimic in C2C12 cells significantly enhanced the glycolysis rate and the mRNA expression of glycolytic enzymes. …”
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Le projecteur Dow au Planétarium de Montréal by Marc-Olivier Cloutier

“…Il a donc fallu que Marc-Oliver Cloutier se fie entièrement au discours du musée et à ses choix concernant l’objet pour identifier la fonction du projecteur. Or, celle-ci a évolué avec le temps. Aujourd’hui placé au centre des regards, sur un piédestal qui supporte sa masse, il s’est mué en objet de curiosité. …”
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Inhibitory Effect on the Tyrosinase Activity and Low Cytotoxicity of Monounsaturated Long-Chain Chelating Fatty Ester by ANTONIO SERGIO C. CARVALHO, TATIANA N. PEDROSA, HERONILDES A. DANTAS FILHO, RAQUEL C. MONTENEGRO, EMERSON S. LIMA, MARNE C. DE VASCONCELLOS, ALBERDAN S. SANTOS

“…Finally, the assay with the series showed no hemolytic activity (EC50> 250 μg mL-1), and not cytotoxic to B16F10, ACP-02, and human dermal fibroblast cells at 100 µM and showed no hemolytic potential at the concentration of IC50 250 µM.…”
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Genetics and pathophysiology of low-renin arterial hypertension by A. L. Markel

“…These syndromes include cases of sporadically occurring somatic mutations in the cells of the adrenal cortex, which begin to produce aldosterone in increased amounts. …”
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Evaluation of Phytochemical Content and the Antioxidant and Antiproliferative Potentials of Leaf Layers of Cabbage Subjected to Hot Air and Freeze-Drying by Do Manh Cuong, Hee Young Kim, Meran Keshawa Ediriweera, Somi Kim Cho

“…Compared to other leaf layers, P1 exhibited high antiproliferative efficacy against pancreatic, breast, and gastric cancer cells. P1 also showed excellent DPPH·(EC 50–4.208 ± 0.033 and 4.611 ± 0.053 mg/mL for hot air and freeze-dried samples, respectively) and ABTS· (2.422 ± 0.068 and 2.224 ± 0.070 mg/mL for hot air and freeze-dried samples, respectively) radical-scavenging effects. …”
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Proton magnetic resonance spectroscopy of neurometabo­lites in the hippocampi of aggressive and tame male rats by R. G. Gulevich, A. E. Akulov, S. G. Shikhevich, R. V. Kozhemyakina, I. Z. Plyusnina

“…In contrast, the elevated proportion of glutamine in aggressive rats vs. tame rats may be indicative of (1) a metabolic disturbance in the glutamate–glutamine cycle, which links neural and glial cells, and (2) decrease in the activity of glutaminase, the enzyme converting glutamine to glutamate (GABA precursor). …”
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Assumer le retrait : pratiques et représentations de la sobriété des jeunes ni aux études ni en emploi au Québec by Quentin Guatieri

“…Cet article s’appuie sur une enquête effectuée dans le cadre d’une thèse doctorale en sociologie soutenue en décembre 2022. Celle-ci portait sur le rapport au travail, à la méritocratie, et à la réussite des jeunes ni aux études, ni en emploi, ni en formation (catégorisés comme NEET) au Québec. …”
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