Stress-Driven Production of γ-Aminobutyric Acid Using Non-Conventional Yeast Strains <i>Kluyveromyces marxianus</i> JMY140K and <i>Metschnikowia reukaufii</i> JMY075 by Ting-Ting Fan, Chao Chen, Du-Wen Zeng, Feng-Lou Wang, Zhao-Xian Xu, Ming-Jie Jin, Yue Zou, Jun Li, Xin-Qing Zhao

“…The culture filtrate of <i>K. marxianus</i> JMY140K also showed promising activities in human skin cells. In addition, <i>K. marxianus</i> JMY140K could also produce GABA using rice straw hydrolysate, which indicated that it has the potential to produce GABA using renewable biomass. …”
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Bio-Recycling Hazelnut Shells to Improve Antioxidant Properties of <i>Lentinus tigrinus</i> Sporophore by Anthea Desiderio, Mariana C. Pedrosa, Sandrina A. Heleno, Marcio Carocho, Daniele B. Rodrigues, Simone Buratti, Irene Soffientini, Daniela Ratto, Elena Savino, Paola Rossi

“…Biological analyses demonstrated that the Lt1_HS extract has higher anti-peroxidant activity (IC₅₀ 0.77 ± 0.01 mg/mL) compared to Lt1_S (IC₅₀ 1.36 ± 0.01 mg/mL) and reduces the accumulation of reactive oxygen species in HaCaT cells by 80%. However, the specific bioactive compounds responsible for these antioxidant effects are still unclear, and further analysis will be conducted. …”
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Foxtail millet supplementation improves glucose metabolism and gut microbiota in rats with high-fat diet/streptozotocin-induced diabetes by Xin Ren, Linxuan Wang, Zenglong Chen, Min Zhang, Dianzhi Hou, Yong Xue, Xianmin Diao, Ruihai Liu, Qun Shen

“…However, FM supplementation could not effectively repair damage to β-cells over a short period of time. In addition, 4 weeks of 48% FM supplementation siginificantly increased the relative abundance of Bifidobacterium and concentration of butyrate, suggesting that the hypoglycemic effects of FM supplementation might be partially mediated by gut microbiota. …”
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Carbamazepine-Mediated Adverse Drug Reactions: CBZ-10,11-epoxide but Not Carbamazepine Induces the Alteration of Peptides Presented by HLA-B∗15:02 by Gwendolin S. Simper, Gia-Gia T. Hò, Alexander A. Celik, Trevor Huyton, Joachim Kuhn, Heike Kunze-Schumacher, Rainer Blasczyk, Christina Bade-Döding

“…Genetically engineered human B-lymphoblastoid cells expressing soluble HLA-B∗15:02 molecules were treated with the drug or its metabolite. …”
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In vitro study of resveratrol as an antioxidant for boar semen preservation: A systematic review by Ragil Angga Prastiya, Trilas Sardjito, Amung Logam Saputro, Sari Yanti Hayanti, Nining Haryuni, Samira Musa Sasi

“…RVT’s antioxidative properties effectively reduced reactive oxygen species and prevented oxidative stress-related damage to sperm cells. Conclusion: The addition of resveratrol to semen extenders enhances the preservation of boar sperm by mitigating oxidative damage, potentially increasing the success rate of AI in the swine industry. …”
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Effects of Copper on Euglena sp. Local Strains and Remediation Capabilities by Witia Ardipeni, Eko Agus Suyono, Nugroho Dewayanto, Na’imatul Mufida, Tia Erfianti, Ria Amelia, Dedy Kurnianto

“…The parameters observed in the study were growth (number of cells and biomass), photosynthetic pigment content (chlorophyll a, chlorophyll b, carotenoid total), Superoxide dismutase enzyme of Euglena sp. as well as the effectiveness of Euglena sp. in copper remediation. …”
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The Developing Progress of Australian Cellular Agriculture in 2023—2024 by TAN Hong-zhuo, FANG Zhong-xiang, YI Cui-ping

“…We have also introduced 3 main technology challenges that Australia agriculture is facing: culture medium for cells, achieving desired taste and texture, and access to infrastructure. …”
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Decursinol angelate relieves inflammatory bowel disease by inhibiting the ROS/TXNIP/NLRP3 pathway and pyroptosis by Yudi Wang, Yudi Wang, Jiamin Wang, Yonghu Chen, Xuezheng Li, Xuezheng Li, Zhe Jiang, Zhe Jiang

“…Enzyme-linked immunosorbent assay (ELISA) was performed to detect the expression levels of pro-inflammatory cytokines in mouse serum, Western blot was performed to detect the expression of TXNIP/NLRP3 pathway tight junction (TJ) proteins in colon tissues and cells, and immunohistochemistry, immunofluorescence and immunohistochemistry, immunofluorescence and qRT-PCR were used to validate the proteins related to this signaling pathway. …”
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Bronchiolitis Severity Affects Blood Count and Inflammatory Marker Levels: A Real-Life Experience by Antonella Gambadauro, Salvatore Mollica, Emanuela Rosa, Federica Xerra, Alessandra Li Pomi, Mariella Valenzise, Maria Francesca Messina, Agata Vitale, Eloisa Gitto, Malgorzata Wasniewska, Giuseppina Zirilli, Sara Manti

“…Prolonged LOS (≥6 days) was associated with high values of total white blood cells, lymphocytes, and eosinophils. Only three inflammatory indexes (PLR, MLR, and PNR) showed a significant association with one outcome (prolonged LOS). …”
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Temporally and Spatially Controlled Age-Related Prostate Cancer Model in Mice by Sen Liu, Keyi Shen, Zixuan Li, Seleste Rivero, Qiuyang Zhang

“…Unlike Pb-Cre knock-in models (which are spatially but not temporally controlled), the expression of Cre is activated to knock out Pten from the mice&#39;s prostate epithelial cells once injected. The viral delivery procedures strictly control the location and time of Pten knockout. …”
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Genome assembly of <i>Vitis rotundifolia</i> Michx. using third-generation sequencing (Oxford Nanopore Technologies) by M. M. Agakhanov, E. A. Grigoreva, E. K. Potokina, P. S. Ulianich, Y. V. Ukhatova

“…‘Dixie’ was sequenced using two MinION flow cells (R9.4.1).…”
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The role of neutrophilia in hyperlactatemia, blood acidosis, impaired oxygen transport, and mortality outcome in critically ill COVID-19 patients by Basma A. Yasseen, Aya A. Elkhodiry, Hajar El-sayed, Mona Zidan, Azza G. Kamel, Mohamed A. Badawy, Marwa S. Hamza, Riem M. El-Messiery, Mohamed El Ansary, Engy A. Abdel-Rahman, Engy A. Abdel-Rahman, Sameh S. Ali

“…Metabolic analysis of different blood cells revealed increased glycolytic activity only when considering the total number of neutrophils.ConclusionThis indicates the role of neutrophilia in hyperlactatemia and lung damage, subsequently contributing to mortality outcomes in severe SARS-CoV-2 infection.…”
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Towards a Rational Design of an Asymptomatic Clinical Herpes Vaccine: The Old, the New, and the Unknown by Aziz Alami Chentoufi, Elizabeth Kritzer, David M. Yu, Anthony B. Nesburn, Lbachir BenMohamed

“…We recently discovered several discrete sets of HSV-1 symptomatic and asymptomatic epitopes recognized by CD4+ and CD8+ T cells from seropositive symptomatic versus asymptomatic individuals. …”
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Biphasic biomimetic scaffolds based on a regionally decalcified bone framework and pre-chondrogenic microspheres for osteochondral defect repair by Zhuo Liang, Qingqing Pan, Fei Xue, Jingdi Zhang, Zhenlin Fan, Weiyun Wang, Xueqiang Guo, Zhuang Qian, Yaping Shen, Wenjuan Song, Lei Wang, Guangdong Zhou, Yong He, Wenjie Ren

“…In vitro studies have shown that axitinib-modified cartilage layers significantly inhibit the VEGF expression of pre-chondrogenic cells, while decalcified bone powder from the bone layer significantly promotes the ossification of PCMs. …”
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Analysis of Several PLA2 mRNA in Human Meningiomas by Yves Denizot, Rafael De Armas, Karine Durand, Sandrine Robert, Jean-Jacques Moreau, François Caire, Nicolas Weinbreck, François Labrousse

“…However no difference was found for PLA2 transcript amounts in relation to the tumor grade, the subtype of meningiomas, the presence of inflammatory infiltrated cells, of an associated edema, mitosis, brain invasion, vascularisation or necrosis. …”
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High‐Performance Pure Water‐Fed Anion Exchange Membrane Water Electrolysis with Patterned Membrane via Mechanical Stress and Hydration‐Mediated Patterning Technique by Yeonjae Lee, Sungjun Kim, Yoseph Shin, Yeram Shin, Seongmin Shin, Sanghyeok Lee, Minseop So, Tae‐Ho Kim, Sehkyu Park, Jang Yong Lee, Segeun Jang

“…Furthermore, the scalability of the technique was demonstrated through successful fabrication and operation of large‐area cells. These findings highlight the potential of this patterning method to advance AEMWE technology, enabling practical applications under pure water‐fed conditions.…”
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Plant Mediated Green Synthesis and Antiviral Activity of Gold and Copper Nanoparticles using Malva parviflora L. Leaf Extract by Seyedeh Raana Charghani, Saadat Rastegarzadeh, Parzhak Zoufan, Seyedeh Elham Rezatofighi

“…The antiviral activity of the compounds was evaluated by measuring the viability of the infected cells by a 3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide (MTT) assay. …”
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Differences in Transcriptional Activation by the Two Allelic (L162V Polymorphic) Variants of PPARα after Omega-3 Fatty Acids Treatment by Iwona Rudkowska, Mélanie Verreault, Olivier Barbier, Marie-Claude Vohl

“…To examine the functional difference of the two allelic variants on receptor activity, transient co-transfections were performed in human hepatoma HepG2 cells activated with EPA, DHA and EPA:DHA mixtures. …”
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The Mechanisms of the Regulation of Immune Response in Patients with Comorbidity of Chronic Obstructive Pulmonary Disease and Asthma by Elena P. Kalinina, Yulia K. Denisenko, Tatyana I. Vitkina, Elena G. Lobanova, Tatyana P. Novgorodtseva, Marina V. Antonyuk, Tatyana A. Gvozdenko, Vera V. Knyshova, Anna V. Nazarenko

“…The specific features in comorbid COPD and asthma were lymphocytosis, increased absolute count of T-helper cells, increased cytotoxic T-lymphocytes in relative and absolute count, increased relative and absolute numbers of B-lymphocytes, and high levels of total IgE. …”
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Advanced surgical techniques and considerations in carotid body tumor management: insights from a cohort study by Farooq Ahmad Ganie, Masarat-ul Gani, Hakeem Zubair Ashraf, Shahbaz Bashir, Iqra Nazir Naqash, Mudasir Hamid Bhat, Shadab Maqsood, Altaf Hussain Mir, Mohd Iqbal Dar

“…These neoplasms originate from the aggregation of chemoreceptor cells in the cervical area, stemming from the neural crest during embryonic development. …”
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