The Role of Gut Microbiota in Tumor Immunotherapy by Miao Wu, Jiawei Bai, Chengtai Ma, Jie Wei, Xianjin Du

“…Some bacteria help fight tumors by activating immunity, while some bacteria mediate immunosuppression to help cancer cells escape from the immune system. More and more studies have revealed that the effects and complications of tumor immunotherapy are related to the composition of the gut microbiota. …”
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USING THE METHODS OF SYSTEMS BIOLOGY FOR PREDICTING PERSPECTIVE TARGET GENES TO SELECT C3 AND C4 CEREALS FOR OXIDATIVE STRESS RESISTANCE by A. V. Doroshkov, A. V. Bobrovskikh

“…Reactive oxygen species (ROS) are some of the most damaging factors for living systems. Cells produce ROS during normal metabolism reactions, but ROS production increases under stressful conditions. …”
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Study of miRNA Based Gene Regulation, Involved in Solid Cancer, by the Assistance of Argonaute Protein by Surya Narayan Rath, Debasrita Das, V Badireenath Konkimalla, Sukanta Kumar Pradhan

“…Solid tumor is generally observed in tissues of epithelial or endothelial cells of lung, breast, prostate, pancreases, colorectal, stomach, and bladder, where several genes transcription is regulated by the microRNAs (miRNAs). …”
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The Role of Intraarterial Chemotherapy in the Management of Retinoblastoma by Aleksandra Pekacka

“…Future advances require a further in-depth understanding of unique genetics of retinoblastoma and complex interactions between tumour cells and their microenvironment.…”
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Breast Cancer Prediction: A Fusion of Genetic Algorithm, Chemical Reaction Optimization, and Machine Learning Techniques by Md. Rafiqul Islam, Md. Shahidul Islam, Saikat Majumder

“…Uncontrolled growth and division of breast cells lead to the formation of tumors, marking the onset of breast cancer. …”
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GC-MS Analysis of phytochemical compounds from Javan olive leaves (Olea javanica) extract and bioactivity screening of antidiabetes through in silico approach by Lailatus Fitri, Ayu Dewi Wulandari, Tri Sumaryono, Nur Fatimah Azzahra Haibaturrahma, Bunga Nanda Agustina, Muhammad Badrut Tamam

“…The Glucokinase (HGKA) enzyme, which is mainly found in the liver and pancreatic beta cells, is involved in maintaining blood glucose homeostasis. …”
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Anti-Inflammatory and Antimicrobial Effects of Herbal Formulation Called Apo-Taat Using Extended-Spectrum ß-Lactamase-Producing Escherichia coli Isolates by Thanakan Kitnithiprapha, Sumalee Panthong, Intouch Sakpakdeejaroen, Sumalee Kondo

“…Effects of herbal extracts on nitric oxide, IL-6, and TNF-α were investigated in RAW 264.7 cells. Results were that Apo-taat extract showed MIC values against ESBL-E. coli in the range of 0.625 to 2.5 mg/mL. …”
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Dynamics in the activity of peroxidase and its isoforms in leaves of different apple cultivars by A. E. Mishko, E. O. Lutskiy

“…Drought and heat lead to an oxidative stress, as reactive oxygen species are produced in plant cells. Plants respond to oxidative damage by activating antioxidant enzymes, such as superoxide dismutase, catalase, and various peroxidases. …”
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Hyperhomocysteinemia-induced VCID results in visual deficits, reduced neuroinflammation and vascular alterations in the retina by Erica M. Weekman, Colin B. Rogers, Tiffany L. Sudduth, Donna M. Wilcock

“…Using our model of hyperhomocysteinemia-induced cSVD, we aimed to identify the effects of cSVD on visual sensitivity and cognition, retinal glial and vascular cells, and neuroinflammatory and cardiovascular gene expression changes. …”
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Deep CNN ResNet-18 based model with attention and transfer learning for Alzheimer's disease detection by Sofia Biju Francis, Sofia Biju Francis, Jai Prakash Verma

“…Alzheimer's disease leads to a rapid and irreversible decline in cognitive abilities by damaging memory cells.MethodsA ResNet-18-based system is proposed, integrating Depth Convolution with a Squeeze and Excitation (SE) block to minimize tuning parameters. …”
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Macrofilaricidal Activity, Acute and Biochemical Effects of Three Lichen Species Found on Mount Cameroon by Thierry Roland Kang, Jerome Nyhalah Dinga, Ayuk Elizabeth Orock, Elvis Monya, Moses Njutain Ngemenya

“…Toxicity of highly active extracts was investigated on monkey kidney epithelial (LLCMK2) cells and in BALB/c mice (2000 mg/kg body weight) including effects on liver enzymes. …”
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Ticam2 ablation facilitates monocyte exhaustion recovery after sepsis by Blake A. Caldwell, Susanti Ie, Amy Lucas, Liwu Li

“…To determine the impact of TICAM2 ablation on innate epigenetic memory in sepsis, we measured genome-wide DNA methylation in bone marrow monocytes and found that Ticam2 -/- cells exhibit a unique profile of altered methylation at CEBPE binding sites and regulatory features for key immune genes such as Dmkn and Btg1. …”
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Hsp90 mutants with distinct defects provide novel insights into cochaperone regulation of the folding cycle. by Rebecca Mercier, Danielle Yama, Paul LaPointe, Jill L Johnson

“…Overexpression or deletion of HCH1 had dramatically opposing effects on the growth of cells expressing different mutants, with a phenotypic shift coinciding with formation of the closed conformation. …”
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Urbane Erinnerungsorte als „villes-mirages“ in schwedischen Reiseberichten der 1990er Jahre by Thomas Mohnike

“…La confrontation de ces observations avec les résultats de recherches sur la mémoire collective comme celles de Pierre Nora ou Jan et Aleida Assmann, incite à se demander dans quelle mesure la recherche d’une continuité effaçant les discontinuités entre hier et aujourd’hui, est un aspect constitutif des lieux de mémoire collective ; ou si, au contraire, la rupture avec le passé irrémédiablement révolu n’est pas décisive pour la structuration de la mémoire collective. …”
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Role of CTCF protein in regulating FMR1 locus transcription. by Stella Lanni, Martina Goracci, Loredana Borrelli, Giorgia Mancano, Pietro Chiurazzi, Umberto Moscato, Fabrizio Ferrè, Manuela Helmer-Citterich, Elisabetta Tabolacci, Giovanni Neri

“…Antisense RNA, like sense transcript, is upregulated in UFM and absent in FXS cells and its splicing is correlated to that of the FMR1-mRNA. …”
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Why Does Pnemococcus Kill? by Yves Bergeron, Michel G Bergeron

“…These steps involve the successive recruitment of polymorphonuclear neutrophils (PMNs). monocytes and lymphocytes; the pulmonary and/or systemic release of inflammatoty mediators that characterize the prebacteremic and bacteremic phases of infection; and the participation of parenchymal cells in the host response. Although the kinetics of cytokines differ considerably from blood to lung tissue to alveoli, and blood levels do not correlate to tissue levels, the kinetics of tumour necrosis factor (TNF) and interleukin-6 in blood, as well as TNF and nitric oxide in bronchoalveolar lavage (BAL) fluid are good indicators of the evolution of the disease. …”
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DREDGING IMPACT ON THE LAKE MANZHEROK (REPUBLIC OF ALTAY) HYDRO/ BIOLOGICAL AND SANITARY/MICRO/BIOLOGICAL CHARACTERISTICS by Dmitry M. Bezmaternykh, Vladimir V. Kirillov, Nadezhda I. Yermolaeva, Laura M. Kipryanova, Lyubov V. Yanygina, Elena Y. Mitrofanova, Olga N. Vdovina, Anton V. Kotovschikov, Evgeniya Y. Zarubina

“…The aquatic communities demonstrated low indicators of development, phytoplankton – 26 taxons, abundance did not exceed 1.3·103 thousand cells/m3, biomass did not exceed 64.0·10-3 mg/m3. …”

Ustilago maydis Trf2 ensures genome stability by antagonizing Blm-mediated telomere recombination: Fine-tuning DNA repair factor activity at telomeres through opposing regulations. by Shahrez Syed, Sarah Aloe, Jeanette H Sutherland, William K Holloman, Neal F Lue

“…We found that deletion of tay1 partially suppresses the telomere aberration of Trf2-depleted cells. Our results thus point to opposing regulation of Blm helicase by telomere proteins as a strategy for optimizing both telomere maintenance and protection. …”
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Optogenetic screening of MCT1 activity implicates a cluster of non-steroidal anti-inflammatory drugs (NSAIDs) as inhibitors of lactate transport. by Scott A Wegner, Hahn Kim, José L Avalos

“…Lactate transport plays a crucial role in the metabolism, microenvironment, and survival of cancer cells. However, current drugs targeting either MCT1 or MCT4, which traditionally mediate lactate import or efflux respectively, show limited efficacy beyond in vitro models. …”
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Kounis Syndrome Secondary to Medicine-Induced Hypersensitivity by Parackrama Karunathilake, Udaya Ralapanawa, Thilak Jayalath, Shamali Abeyagunawardena

“…Kounis syndrome is mediated by mast cells that interact with macrophages and T-lymphocytes, causing degranulation and inflammation with cytokine release. …”
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