Synergistic effects of alginate oligosaccharide and cyanidin-3-O-glucoside on the amelioration of intestinal barrier function in mice by Jie Li, Yuanjie Guo, Liyuan Ma, Yixiang Liu, Chao Zou, Huiying Kuang, Bing Han, Yingliang Xiao, Yanbo Wang

“…Emerging evidence shows that dietary oligosaccharides are important prebiotics that can improve intestinal flora, while dietary polyphenols can act directly on intestinal cells. However, information about their synergistic effects on gut health is still limited. …”
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Update on the Progress of Musashi-2 in Malignant Tumors by Yiting Niu, Tao Zhou, Yanjun Li

“…Since the discovery of the Musashi (MSI) protein, its ability to affect the mitosis of Drosophila progenitor cells has garnered significant interest among scientists. …”
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Erythrocyte Shape Abnormalities, Membrane Oxidative Damage, and β-Actin Alterations: An Unrecognized Triad in Classical Autism by Lucia Ciccoli, Claudio De Felice, Eugenio Paccagnini, Silvia Leoncini, Alessandra Pecorelli, Cinzia Signorini, Giuseppe Belmonte, Roberto Guerranti, Alessio Cortelazzo, Mariangela Gentile, Gloria Zollo, Thierry Durand, Giuseppe Valacchi, Marcello Rossi, Joussef Hayek

“…Autism spectrum disorders (ASDs) are a complex group of neurodevelopment disorders steadily rising in frequency and treatment refractory, where the search for biological markers is of paramount importance. Although red blood cells (RBCs) membrane lipidomics and rheological variables have been reported to be altered, with some suggestions indicating an increased lipid peroxidation in the erythrocyte membrane, to date no information exists on how the oxidative membrane damage may affect cytoskeletal membrane proteins and, ultimately, RBCs shape in autism. …”
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A ketogenic diet regulates microglial activation to treat drug addiction by Jie Ji, Yi Tang

“…Many studies have shown that psychoactive substances may act directly on immune cells, altering their function and inducing the production of various inflammatory mediators. …”
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The deleterious effects of CDK4/6 inhibition on renal recovery post-acute kidney injury by Shanshan Zhou, Rouzhang Peng, Yanting Shen, Liuwei Huang, Suying Han, Jun Wang, Jie Guo

“…Furthermore, dasatinib (D) plus quercetin (Q) were used to eliminate senescent cells in ischemic AKI murine model and Palb was administered post the treatment of D + Q. …”
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Genetic Risk Prediction for Normal-Karyotype Acute Myeloid Leukemia Using Whole-Exome Sequencing by Seong Gu Heo, Eun Pyo Hong, Ji Wan Park

“…We searched for somatic mutations from 10 pairs of tumor and normal cells by using a highly efficient and reliable analysis workflow for whole-exome sequencing data and performed association tests between the NK-AML and somatic mutations. …”
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Monoclonal anti-CD38 therapy in human myeloma: retrospects and prospects by Alberto L. Horenstein, Angelo C. Faini, Angelo C. Faini, Fabio Morandi, Erika Ortolan, Paola Storti, Nicola Giuliani, Nicola Giuliani, Paul G. Richardson, Fabio Malavasi, Fabio Malavasi

“…By gaining a deeper understanding of interactions between therapeutic antibodies, myeloma cells, and the tumor microenvironment (TME), it is hoped that previously unrecognized vulnerabilities within the disease may be revealed, paving the way to more effective treatment strategies.…”
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Radiological images of an advanced invasive carcinoma with mucinous aspects: A case report by Chiara Adriana Pistolese, MD, PhD, Francesca Di Giuliano, MD, PhD, Martina Cerocchi, MD, Maria Volpe, MD, Martina Cerasi Dellanea, MD, Flavia Briganti, MD, Paola Elda Gigliotti, MD, Carolina Goffredo, MD, Lucia Giudice, MD, Diletta Caccia, MD, Francesca Servadei, MD, Adriano De Majo, MD, PhD, Marco Materazzo, MD, Giorgio Pistilli, MD, Gianluca Vanni, MD, PhD, Valeria Liberto, MD

“…Mucinous carcinoma is characterized by clusters of epithelial tumour cells suspended in pools of extracellular mucin and is further divided in 2 subgroups, pure and mixed. …”
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Synthesis, DNA-Binding, Anticancer Evaluation, and Molecular Docking Studies of Bishomoleptic and Trisheteroleptic Ru-Diimine Complexes Bearing 2-(2-Pyridyl)-quinoxaline by Sofia Balou, Athanasios Zarkadoulas, Maria Koukouvitaki, Luciano Marchiò, Eleni K. Efthimiadou, Christiana A. Mitsopoulou

“…MTT experiments revealed that both complexes induce apoptosis of MCF-7 (breast cancer) cells in low concentrations. Confocal microscopy indicated that 2 localizes in the nucleus and internalizes more efficiently in MCF-7 than in HEK-293.…”
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A Proof-of-Concept for Safety Evaluation of Inhalation Exposure to Known Respiratory Irritants Using In Vitro and In Silico Methods by Nikaeta Sadekar, Holger Peter Behrsing, Tanja Hansen, Vivek Patel, Hazel Paulo, Alex Rae, Detlef Ritter, Katharina Schwarz, Anne Marie Api

“…Three in vitro systems, representing the upper (MucilAir™—nasal epithelial tissue) and lower (A549 cells and human precision-cut lung slices) human respiratory regions, were exposed to six respiratory irritants. …”
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ROS-Mediated NLRP3 Inflammasome Activity Is Essential for Burn-Induced Acute Lung Injury by Shichao Han, Weixia Cai, Xuekang Yang, Yanhui Jia, Zhao Zheng, Hongtao Wang, Jun Li, Yan Li, Jianxin Gao, Lei Fan, Dahai Hu

“…The use of ROS scavenger N-acetylcysteine (NAC) partially reversed NLRP3 inflammasome activity in cells exposed to burn serum. These results indicate that the NLRP3 inflammasome plays an essential role in burn-induced ALI and that burn-induced NLRP3 inflammasome activity is a partly ROS-dependent process. …”
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A two-scale computational homogenization approach for elastoplastic truss-based lattice structures by Hooman Danesh, Lisamarie Heußen, Francisco J. Montáns, Stefanie Reese, Tim Brepols

“…The framework is applied to three types of stretching-dominated lattice topologies, including triangular, X-braced, and X-Plus-braced unit cells. The macroscopic structure is represented as a two-dimensional continuum, while the microscale lattice is modeled as a network of truss elements, significantly reducing computational cost. …”
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Lepidium sativum Seed Extract-Mediated Synthesis of Zinc Oxide Nanoparticles: Structural, Morphological, Optical, Hemolysis, and Antibacterial Studies by Adnan Alnehia, Annas Al-Sharabi, Abdel-Basit Al-Odayni, A. H. Al-Hammadi, Fares H. AL-Ostoot, Waseem Sharaf Saeed, Naaser A. Y. Abduh, Ali Alrahlah

“…The hemolysis assay showed no potential harm due to ZnO NPs toward red blood cells if utilized in low doses. As a result, it could be concluded that the reported biogenic method for synthesizing ZnO NPs is promising, resulting in hemocompatible NPs and comparable bactericidal agents.…”
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Low Concentrations of Corticosterone Exert Stimulatory Effects on Macrophage Function in a Manner Dependent on Glucocorticoid Receptors by He-Jiang Zhong, Hai-Yan Wang, Ce Yang, Jian-Yun Zhou, Jian-Xin Jiang

“…Endogenous glucocorticoids (GCs) have both stimulatory and suppressive effects on immune cells depending on the concentration. However, the mechanisms underlying the stimulatory effects of GCs remain elusive. …”
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Atypical Lipomatous Tumor/Well-Differentiated Liposarcoma with Intramuscular Lipoma-Like Component of the Thigh by Chairat Burusapat, Nuttadon Wongprakob, Nutthapong Wanichjaroen, Chatchai Pruksapong, Kantang Satayasoontorn

“…Atypical lipomatous tumor/well-differentiated liposarcoma (ALT/WDLPS) is a locally aggressive mesenchymal neoplasm composed either entirely or partly of an adipocytic proliferation showing at least focal nuclear atypia in both adipocytes and stromal cells. ALT most frequently occurs in deep soft tissue of proximal extremities (thigh and buttock) and usually presents as a deep-seated, painless mass that can slowly attain a very large size, which is one of the most common sarcomas of extremity. …”
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IL-17 and IL-22 in Cerebrospinal Fluid and Plasma Are Elevated in Guillain-Barré Syndrome by Shujuan Li, Ming Yu, Haifeng Li, Hongliang Zhang, Yanfang Jiang

“…Meanwhile, the elevated levels of these two cytokines in plasma suggest the activation of Th17 and Th22 cells in the systemic immune response of GBS. Our data provide preliminary evidence that GBS is associated with high levels of IL-17 and IL-22 in CSF and plasma. …”
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Curcumin-enhanced NIR-II-responsive gold nanobipyramids for targeted HSP 90 inhibition by Zhenying Diao, Youcheng Liang, Yong Liu, Dou Zhang, Long Qiu, Jianbo Sun, Qiaoyou Lu, Yanlei Liu, Daxiang Cui, Ting Yin

“…Meanwhile, Cur served as chemotherapeutic agents to induce apoptosis in tumor cells. In vivo photoacoustic imaging-guided, GNBs-Cur achieved effective tumor elimination through mild-photothermal chemotherapy without systemic toxicity. …”
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Chrysoeriol ameliorates hyperglycemia by regulating the carbohydrate metabolic enzymes in streptozotocin-induced diabetic rats by Baskaran Krishnan, Abirami Ramu Ganesan, Ravindran Balasubramani, Dinh Duc Nguyen, Soon Woong Chang, Shaoyun Wang, Jianbo Xiao, Balamuralikrishnan Balasubramanian

“…The histopathological study confirmed that renewal of the beta cells of pancreatic of chrysoeriol and glibenclamide treated rats. …”
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Positron Emission Tomography—Computer Tomography Scan Used as a Monitoring Tool Following Cellular Therapy in Cerebral Palsy and Mental Retardation—A Case Report by Alok Sharma, Hemangi Sane, Amruta Paranjape, Nandini Gokulchandran, Pooja Kulkarni, Anjana Nagrajan, Prerna Badhe

“…He was treated with cellular therapy of Autologous Bone Marrow Derived Mono-Nuclear Cells (MNCs) transplantation followed by multidisciplinary rehabilitation. …”
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The Serum S100B Level as a Biomarker of Enteroglial Activation in Patients with Ulcerative Colitis by Asuman Celikbilek, Mehmet Celikbilek, Seda Sabah, Nermin Tanık, Elif Borekci, Serkan Dogan, Yavuz Akin, Suleyman Baldane, Kemal Deniz, Neziha Yilmaz, Omer Ozbakir, Mehmet Yucesoy

“…Recent studies have demonstrated that enteric glial cells (EGC) participate in the homeostasis of the gastrointestinal tract. …”
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