HMGB-1 as a Novel Predictor of Disease Severity and Prognosis in Patients with Hemorrhagic Fever with Renal Syndrome by Hong Du, Jing Li, Haitao Yu, Jianqi Lian, Ye Zhang, Ying Zhang, Xuefan Bai, Pingzhong Wang

“…The levels of white blood cells (WBC), platelets (PLT), hematocrit (HCT), albumin (ALB), blood urea nitrogen (BUN), serum creatinine (Scr), and uric acid (UA) were routinely tested in the same time frame. …”
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Neurobehavioral plasticity in the rodent gustatory system induced by regular consumption of a low-calorie sweetener during adolescence by Clare M. Mathes, Sarah J. Terrill, Juan P. Taborda-Bejarano, Sandrine Chometton, Mallory J. Witt, Gaurikka Mendiratta, Emily G. Gilman, Delenn R. Hartswick, Bo M. Anderson, Lindsey A. Schier

“…Ace-K exposure also led to a significant reduction in dopamine-producing cells of the ventral tegmental area. The collective findings reveal that LCS intake early in life alters the taste-brain axis and the behavioral responsiveness to both positive and negative tastants that are important determinants of dietary preferences.…”
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Sustainable utilization of bovine adipose tissue derivatives as robust antimicrobial agents against Methicillin-resistant Staphylococcus aureus by Muhammed Abdelhameed Ismael Alcici, Salma Waheed Abdelhaleem, Karima Mogahed Fahim, Neveen Mohamed Saleh, Heba Saeed Farag

“…In this study, the use of mechanically isolated mature adipose cells (MIMACs) and their lysate (Adipolysate) as a new sustainable antimicrobial agent was assessed against Methicillin-resistant Staphylococcus aureus (MRSA). …”
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<i>Garcinia brasiliensis</i> Leaves Extracts Inhibit the Development of Ascitic and Solid Ehrlich Tumors by Lucas Sylvestre Silva, Eduardo Cavallini, Rafael André da Silva, Monielle Sant’Ana, Ariane Harumi Yoshikawa, Thiago Salomão, Bianca Huang, Paula Craice, Luiz Philipe de Souza Ferreira, Heitor Pedro Della Matta, Cristiane Damas Gil, Maria de Lourdes Gomes Pereira, Ana Paula Girol

“…Furthermore, both treatments were effective in inhibiting tumor growth in EA and ES by modulating the levels of interleukin (IL)-6 and tumor necrosis factor (TNF)-α, decreasing mast cells numbers and inducing apoptosis. <b>Conclusions</b>: This research indicates that both CE and EAF from <i>G. brasiliensis</i> leaves have potential antitumor effects with low cytotoxicity.…”
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Structural Characteristics and Inhibiting Oxidative Stress of Nine-steaming-nine-processing Polygonatum Kingianum Coll.et Hemsl Polysaccharides by LIU Yu-bin, CHEN Chang-an, SU Yi-lin, LUO Zhen, YAN Jin, LI Pan, DU Bing

“…In vitro cellular experiments showed that NPKP significantly reduced reactive oxygen species (ROS) levels in HepG2 cells. It also upregulated antioxidant enzymes, including superoxide dismutase (SOD), catalase (CAT), and glutathione (GSH), alleviating oxidative stress induced by free fatty acids. …”
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Lumbar Ureteral Stenosis due to Endometriosis: Our Experience and Review of the Literature by Salvatore Butticè, Antonio Simone Laganà, Valeria Barresi, Antonino Inferrera, Giuseppe Mucciardi, Antonina Di Benedetto, Carmela Emanuela D'Amico, Carlo Magno

“…Immunohistochemical test of the glandular epithelium showed positivity for estrogen and progesterone receptors and moreover stromal cells were positive for CD10. The finding suggested a very rare diagnosis of isolated lumbar ureteral endometriosis.…”
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Intercellular communication is crucial in the regulation of healthy aging via exosomes by Huifang Sun, Tengyuan Xia, Shuting Ma, Tao Lv, Yuhong Li

“…The hallmarks of aging encompass a variety of molecular categories (genomic, telomeric, and epigenetic), organelles (proteostasis, autophagy, and mitochondria), cellular components (including stem cells), systems (such as intercellular communication and chronic inflammation), and environmental factors (dysbiosis and nutrient sensing). …”
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Nanotechnology-assisted cryopreservation of ovine semen: evaluation of Thymus vulgaris essential oil as a natural antioxidant by Samia Khnissi, Rania Maaloul, Hela Chalouati, Laura Mara, Dorra Aouadi, Basma Adouani, Maria Dattena, Ikram Khémiri, Sami Fattouch

“…The quality of the semen diluted in the prepared media after preservation at 4°C and 15°C was examined by measuring the two parameters indicative of semen quality: semen motility and progressivity refer to the ability of ram sperm cells to move actively and efficiently, which is crucial for successful fertilization. …”
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Th1 and Th2 cytokine profile in patients with early onset periodontitis and their healthy siblings by Jiřina Bártová, Zuzana Krátká-Opatrná, Jarmila Procházková, Otakar Krejsa, Jana Dušková, Lubor Mrklas, Helena Tlaskalová, Božena Cukrowská

“…Peripheral blood mononuclear cells (PBMC) were isolated and cultivated for 24 h and 7 days with PWM, A. a. or Escherichia coli. …”
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The Impact of Oxford Nanopore Technologies Based Methodologies on the Genome Sequencing and Assembly of Romanian Strains of <i>Drosophila suzukii</i> by Attila Cristian Ratiu, Adrian Ionascu, Nicoleta Denisa Constantin

“…Methods: We implemented both MinION and Flongle flow-cells and tested the impact of various basecalling models and assembly strategies on the quality of the sought-after representative genome assemblies. …”
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Drosophila ubiquitin-specific peptidase 14 stabilizes the PERIOD protein by regulating a ubiquitin ligase SLIMB by So Who Kang, Jung-Eun Park, Soonhyuck Ok, Minhui Um, Hyeonjeong Son, Seunghee Byun, Nayoung Park, Su Jin Lee, Thị Xuân Thùy Trần, Gyeongmin Kim, Jeonghun Yeom, Kyunggon Kim, Eun Young Kim, Min-Ji Kang

“…We find that overexpression of USP14 in clock cells reduces PER protein levels without altering its mRNA levels whereas USP14 knockdown increases PER protein levels, suggesting that USP14 regulates PER post-translationally. …”
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Effect of 3-hydrazinylquinoxaline-2-thiol hydrogel on skin wound healing process in diabetic rats by Jehan Barakat Alamre, Huda Alkreathy, Ahmed S. Ali, Abdelbagi Alfadil, Sahar S. Alghamdi

“…The healing effect was additionally evaluated by the inhibition of the inflammatory response of interleukin (IL)—1β interleukin (IL)—6, tumor necrosis factor (TNF-α) and nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) with a marked improvement of the transforming growth factor beta (TGFβ-1), antioxidant markers and collagen-1. …”
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Commercially Supplied Amine-Modified siRNAs May Require Ultrafiltration prior to Conjugation with Amine-Reactive Compounds by Shannen Lau, Bim Graham, Ben J. Boyd, Colin W. Pouton, Paul J. White

“…Conjugation of siRNA to macromolecules such as serum albumin has multiple potential benefits, including enhanced extravasation via albumin-mediated transcytosis across endothelial cells and reduced renal clearance. In attempting to conjugate siRNA to albumin, we used commercially sourced amine-modified siRNA and reacted it with the heterobifunctional linker succinimidyl 4-[N-maleimidomethyl]cyclohexane-1-carboxylate (SMCC) to introduce a maleimide group suitable for conjugation to the thiol group of the surface-exposed cysteine residue (Cys 34) within albumin. …”
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Investigating charge dynamics at lead halide perovskite single crystal surfaces by Birgit Kammlander, Alberto García-Fernández, Sebastian Svanström, Erika Giangrisostomi, Ruslan Ovsyannikov, Håkan Rensmo, Ute B Cappel

“…To further develop lead halide perovskites for their application in solar cells, understanding the material’s fundamental behavior under illumination is necessary. …”
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Novel Mechanisms Modulating Palmitate-Induced Inflammatory Factors in Hypertrophied 3T3-L1 Adipocytes by AMPK by Naru Morita, Toshio Hosaka, Atsuko Kitahara, Toshitaka Murashima, Hirohisa Onuma, Yoshikazu Sumitani, Kazuto Takahashi, Toshiaki Tanaka, Takuma Kondo, Hitoshi Ishida

“…Results. Palmitate-preloaded cells exhibited significant increase in MCP-1 release and triglyceride (TG) deposition. …”
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Interleukin-18 Increases TLR4 and Mannose Receptor Expression and Modulates Cytokine Production in Human Monocytes by Luciane Alarcão Dias-Melicio, Reginaldo Keller Fernandes, Daniela Ramos Rodrigues, Marjorie Assis Golim, Angela Maria Victoriano Campos Soares

“…However, IL-18 was unable to induce neither IL-12 nor IL-15 production by these cells. Taken together, these results show an important role of IL-18 on the early phase of inflammatory response by promoting the expression of some pattern recognition receptors (PRRs) that are important during the microbe recognition phase and by inducing some important cytokines such as TNF-α and IL-10.…”
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Chemical test and cellular bioactivities and flavor enhancer properties of mung bean protein via glycation reaction by Srisukpachin Nuttakarn, Tabtimmai Lueacha, Sedtananun Saranya, Laohakunjit Natta, Sonklin Chanikan

“…MRP exhibited non-toxic in Vero cells at 10 mg/mL and it significantly suppressed nitric oxide (NO) release to 18.62 µM with non-toxicity in the murine macrophage; RAW 264.7 at a concentration of 1 mg/mL.…”
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AbaComplex Enhances Mitochondrial Biogenesis and Adipose Tissue Browning: Implications for Obesity and Glucose Regulation by Serena Sagliocchi, Elisabetta Schiano, Lucia Acampora, Fortuna Iannuzzo, Annunziata Gaetana Cicatiello, Caterina Miro, Annarita Nappi, Federica Restolfer, Mariano Stornaiuolo, Stefano Zarrilli, Fabrizia Guerra, Gian Carlo Tenore, Monica Dentice, Ettore Novellino

“…The browning of WAT, whereby white fat cells acquire characteristics of brown adipose tissue (BAT) with enhanced thermogenic capacity, represents a promising strategy to enhance metabolic health. …”
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Regulation of Stress-Induced Immunosuppression in the Context of Neuroendocrine, Cytokine, and Cellular Processes by Evgenii Balakin, Ksenia Yurku, Mark Ivanov, Alexander Izotov, Valeriya Nakhod, Vasiliy Pustovoyt

“…A significant portion of the data confirms that the activation of the hypothalamic–pituitary–adrenal (HPA) axis and subsequent elevation of cortisol levels exert substantial immunosuppressive effects on immune cells, particularly macrophages and lymphocytes, leading to the suppression of innate and adaptive immune responses. …”
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Health Status of Spiny Lobster Panulirus homarus with Sub-Mersible Net Cage System in the Different Depths at Kepulauan Seribu, DKI Jakarta by Dinamella Wahjuningrum, Irzal Effendi, Yani Hadiroseyani, Tatag Budiardi, Iis Diatin, Mia Setiawati, Yuni Puji Hastuti, Agus Oman Sudrajat, Yonvitner, Sri Nuryati, Putri Utami

“…Based on the above observations, the depth does not affect the immune response, there is no visible damage to the cells and tissues of the lobster hepatopancreas. …”
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