Muscle-derived extracellular vesicles mediate crosstalk between skeletal muscle and other organs by Jiajie Jia, Jiajie Jia, Lu Wang, Lu Wang, Yue Zhou, Peng Zhang, Xiaoping Chen

“…Numerous bioactive molecules are secreted by SKM and transported by extracellular vesicles (EVs), a novel class of mediators of communication between cells and organs that contain various types of cargo molecules including lipids, proteins and nucleic acids. …”
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Challenging a Misnomer? The Role of Inflammatory Pathways in Inflammatory Breast Cancer by Riley J. Morrow, Nima Etemadi, Belinda Yeo, Matthias Ernst

“…The role of the tumor microenvironment, through tumor-associated macrophages, infiltrating lymphocytes, and cancer stem cells is also discussed, suggesting that these tumor extrinsic factors may help account for the differences in behavior between inflammatory breast cancer and noninflammatory breast cancer. …”
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Concomitant Treatment with Etanercept and Tacrolimus Synergistically Attenuates Arthritis Progression via Inhibition of Matrix Metalloproteinase-3 Production and Osteoclastogenesis... by Iwao Seki, Miwa Takai-Imamura, Tomomi Kohara-Tanaka, Satoshi Shirae, Minoru Sasano, Hiroaki Matsuno, Hiroyuki Aono

“…The combined treatment exhibited synergistic effects of the two drugs in reducing the serum matrix metalloproteinase-3 level and the number of peripheral CD11bhigh osteoclast precursor cells. Moreover, tacrolimus inhibited the cytokine-induced osteoclast differentiation in synergy with etanercept in an in vitro assay. …”
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Studies on the biological effects of ozone: 8. Effects on the total antioxidant status and on interleukin-8 production by V. Bocci, G. Valacchi, F. Corradeschi, G. Fanetti

“…On the other hand plasma and cells are endowed with a powerful antioxidant system so that a fairly wide range of O3 concentrations between 40 and 80μ g/ml per gram of blood (˜0.83-1.66 mM) are effective but not deleterious. …”
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Fundus Images-Based Detection and Grading of Macular Edema Using Robust Macula Localization by Adeel M. Syed, M. Usman Akram, Tahir Akram, Muhammad Muzammal, Shehzad Khalid, Muazzam Ahmed Khan

“…The fovea contains large concentrations of cone cells and is responsible for sharp, colored vision. …”
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Induced-volatolomics, a new research field in chemical biology by Blochouse, Estelle, Eid, Rony, Cannoni, Elsa, Châtre, Rémi, Geffroy, Claude, Opalinski, Isabelle, Papot, Sébastien, Poinot, Pauline

“…Once activated, VOC-based probes release volatile tracers that inform the biochemical processes arising in cells, liquid and solid biopsies, and even in entire organisms. …”
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Melanoma bone metastasis-induced osteocyte ferroptosis via the HIF1α-HMOX1 axis by Yewei Jia, Rui Li, Yixuan Li, Katerina Kachler, Xianyi Meng, Andreas Gießl, Yi Qin, Fulin Zhang, Ning Liu, Darja Andreev, Georg Schett, Aline Bozec

“…Abstract Osteocytes are the main cells in mineralized bone tissue. Elevated osteocyte apoptosis has been observed in lytic bone lesions of patients with multiple myeloma. …”
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Apolipoprotein C-II Deposition Amyloidosis: A Potential Misdiagnosis as Light Chain Amyloidosis by Sadichhya Lohani, Emily Schuiteman, Lohit Garg, Dhiraj Yadav, Sami Zarouk

“…Bone marrow biopsy revealed minimal involvement with amyloidosis with kappa monotypic plasma cells on flow cytometry. She was started on chemotherapy for light chain amyloidosis. …”
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Programmable Macrophage Vesicle Based Bionic Self‐Adjuvanting Vaccine for Immunization against Monkeypox Virus by Weiqiang Lin, Chenguang Shen, Mengjun Li, Shengchao Ma, Chenxin Liu, Jialin Huang, Zuning Ren, Yuechao Yang, Minghai Zhao, Qiulin Xie, Shuang Guo, Wei Wang, Kaiyuan Wang, Qiang Ma, Yideng Jiang, Judun Zheng, Yuhui Liao

“…Owing to the synergistic properties of bionic vaccine coloaded MV and EV protein in defensing MPV, the activation ratio of antigen‐presenting cells is nearly four times than that of single antigen in the same dose, resulting in stronger immunity in host. …”
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Respiratory Epithelium Lined Cyst of the Maxilla: Differential Diagnosis by C. P. Martinelli-Kläy, S. Chatelain, F. Salvado, T. Lombardi

“…Ciliated and rare mucous cells were also observed. The diagnosis could evoke a surgical ciliated cyst mimicking the radicular cyst but the patient has no previous history of trauma or surgery in the maxillofacial region. …”
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OsSLI1, a Homeodomain Containing Transcription Activator, Involves Abscisic Acid Related Stress Response in Rice (Oryza sativa L.) by Xi Huang, Min Duan, Jiakai Liao, Xi Yuan, Hui Chen, Jiejie Feng, Ji Huang, Hong-Sheng Zhang

“…The OsSLI1-GFP fusion protein was localized in the nucleus of rice protoplast cells and the transcriptional activity of OsSLI1 was confirmed by the yeast hybrid system. …”
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Purine but Not Pyrimidine De Novo Nucleotide Biosynthesis Inhibitors Strongly Enhance the Antiviral Effect of Corresponding Nucleobases Against Dengue Virus by Laurent F. Bonnac, Christine D. Dreis, Madhu Rai, Robert J. Geraghty

“…Antiviral nucleobases are converted in infected cells to their corresponding nucleoside triphosphate active form. …”
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Changes in Angiotensin Receptor Distribution and in Aortic Morphology Are Associated with Blood Pressure Control in Aged Metabolic Syndrome Rats by Verónica Guarner-Lans, Elizabeth Soria-Castro, Rocío Torrico-Lavayen, Araceli Patrón-Soberano, Karla G. Carvajal-Aguilera, Vicente Castrejón-Tellez, María Esther Rubio-Ruiz

“…Electron microscopy images showed premature aging in MS since the increased fibrosis, enlarged endothelium, and invasion of this layer by muscle cells that was present in control 18-month-old aortas were also found in 6-month-old aortas from MS rats. …”
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Spectrum of Cytopathological Causes of Cervical Lymphadenopathy- An Experience at Sahiwal Teaching Hospital by Raees Abbas Lail, Areeba Farooq, Qurrat-ul-Ain Tahir, Sadaf Shafique, Syeda Tooba Fatmi, Abdul Ghaffar

“…The least common cause of cervical lymphadenopathy appeared to be Hodgkin’s lymphoma and malignant cells that appeared in equal ratios. Conclusion: FNAC helped us in determining granulomatous inflammation, most likely Tuberculosis as the most common cause of cervical lymphadenopathy which is consistent with data obtained from most developing countries. …”
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Systematic expression analysis of cysteine‐rich secretory proteins, antigen 5, and pathogenesis‐related 1 protein (CAP) superfamily in Arabidopsis by Megumi Matsuzawa, Takumi Nakayama, Masa H. Sato, Tomoko Hirano

“…In particular, CAP51, CAP52, and CAP53 were specifically expressed in the cortical cells at the lateral root developing regions, suggesting that these genes may function in lateral root development. …”
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Localized molecular chaperone synthesis maintains neuronal dendrite proteostasis by Célia Alecki, Javeria Rizwan, Phuong Le, Suleima Jacob-Tomas, Mario Fernandez Comaduran, Morgane Verbrugghe, Jia Ming Stella Xu, Sandra Minotti, James Lynch, Jeetayu Biswas, Tad Wu, Heather D. Durham, Gene W. Yeo, Maria Vera

“…Stress-mediated HSPA8 mRNA localization to the dendrites is impaired by depleting fused in sarcoma—an amyotrophic lateral sclerosis-related protein—in cultured spinal cord mouse motor neurons or by expressing a pathogenic variant of heterogenous nuclear ribonucleoprotein A2/B1 in neurons derived from human induced pluripotent stem cells. These results reveal a neuronal stress response in which RNA-binding proteins increase the dendritic localization of HSPA8 mRNA to maintain proteostasis and prevent neurodegeneration.…”
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Current status and advances in zinc anodes for rechargeable aqueous zinc-air batteries by Muhammad Afiq Irfan Mohd Shumiri, Abdillah Sani Mohd Najib, Nor Akmal Fadil

“…By integrating the principles of traditional zinc-ion batteries and fuel cells, ZABs offer remarkably high theoretical energy density at lower production cost compared to the current state-of-the-art lithium-ion batteries (LIBs). …”
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Structural characterization and immunostimulatory activity of a water-soluble polysaccharide from abalone (Haliotis discus hannai Ino) muscle by Linfan Shi, Gengxin Hao, Jun Chen, Junling Wang, Wuyin Weng

“…In addition, AMPP was found to possess potent immunostimulatory activity via rising phagocytosis of RAW264.7 cells and promoting secretion of TNF-α.…”
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Disseminated Histoplasmosis as an AIDS-Defining Illness Presenting as Fever of Unknown Origin in an 11-Year-Old Female by Kathryn E. Kalata, Christina Osborne, Amy Willis, Kacey Navarro, Laura Z. Fenton, Christiana Smith

“…Additional testing confirmed the diagnosis of HIV/AIDS with a CD4 count of 52 cells/mm3, complicated by disseminated histoplasmosis. …”
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Topical application of the ethanol extract and the hydroethanolic fraction of ripe Solanum lycocarpum A. St. Hil. fruit improves the healing of excisional wounds by Elisângela Elduina Ferreira, Renan Diniz Ferreira, Milena Santos de Almeida, Renan Araújo Costa, Izabela Caputo Assis Silva, Melissa Grazielle Morais, Karen Helaine Mendes Bertolin, Paula Vieira Teixeira Vidigal, Raquel Alves Costa, Luciana Alves Rodrigues dos Santos Lima, Flávia Carmo Horta Pinto

“…At the end of this period, the animals were euthanized, and the lesions were subjected to histopathological processing and analysis to evaluate macroscopic area of the wound and microscopic analysis by morphometry of the number of leukocytes, mast cells, fibroblasts, re-epithelialization, and matrix deposition. …”
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