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7621
Synthesis of pyranopyrazolo N-glycoside and pyrazolopyranopyrimidine C-glycoside derivatives as promising antitumor and antimicrobial agents
Published 2015-09-01“…As a part of systematic investigation of the synthesis and biological activities of pyrazole analogues linked to various heterocyclic systems, a new series of pyrazolo-N-glycoside derivatives, pyrazolopyranopyrimidine and C-glycoside of pyrazolopyranotriazolo-pyrimidine derivatives was synthesized through the reaction of the key intermediate 6-amino-3-methyl-4-(substituted-phenyl)-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile (3a,b) with different reagents. …”
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7622
Experimental Investigation on E-Waste Concrete Using Mineral Admixtures
Published 2024-01-01“…Our research aims to understand how both the amount of e-waste and the specific mineral admixtures used influence the final properties of the concrete. We systematically replaced the fine aggregate with e-waste at varying percentages (0%, 10%, 20%, and 30%) and meticulously analyzed the resulting effects. …”
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7623
Heberferón®’s economic feasibility in patients with high-grade brain tumors without therapeutic options
Published 2024-07-01“…The effectiveness parameter for each of the comparators was obtained by doing a systematic search in Medline (Pubmed) and Cochrane.<br /><strong>Results:</strong> Heberferón® was less expensive for each month of life saved in relation to the rest of the medications.…”
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7624
Parametric Estimation of Directional Wave Spectra from Moored FPSO Motion Data Using Optimized Artificial Neural Networks
Published 2025-01-01“…Artificial neural networks (ANNs), trained and optimized through hyperparameter tuning and feature selection, are employed to estimate wave parameters including the significant wave height, peak period, main wave direction, enhancement parameter, and directional-spreading factor. A systematic correlation analysis ensures that informative input features are retained, while extensive sensitivity tests confirm that richer input sets notably improve predictive accuracy. …”
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7625
Aflatoxin B1 impairs the growth and development of chicken PGCs through oxidative stress and mitochondrial dysfunction
Published 2025-01-01“…Primordial germ cells (PGCs) in chickens, as ancestral cells of gametes, are essential for genetic transmission, yet the impact and mechanisms of aflatoxins on them remain elusive. This study systematically investigated the effects of aflatoxin B1 (AFB1) on chicken PGCs and their potential mechanisms using an in vitro culture model. …”
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7626
A deep learning approach for early prediction of breast cancer neoadjuvant chemotherapy response on multistage bimodal ultrasound images
Published 2025-01-01“…Abstract Neoadjuvant chemotherapy (NAC) is a systemic and systematic chemotherapy regimen for breast cancer patients before surgery. …”
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7627
Detecting and measuring Microplastic pollution in Al Hoceima City's harbor, northern Morocco
Published 2025-06-01“…In December 2023, surface water and sediment samples were systematically collected using manta nets and core samplers. …”
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7628
Eye Gaze and Dominance, Cues for Online Communication with Strangers
Published 2022-12-01“…Analysis of the data revealed no systematic differences between males and females.…”
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7629
Influence of Time of Mission on Correct Diagnosis by the Prehospital Emergency Physician: A Retrospective Study
Published 2019-01-01“…Over a period of 12 months, all patient care reports of the emergency medical services in Bad Belzig were examined. By systematically comparing the prehospital suspected diagnosis to the discharge diagnosis, the DM was determined after careful examination of the entire course of each patient’s case, blinded to time of mission. …”
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7630
Nerve Blockage Attenuates Postoperative Inflammation in Hippocampus of Young Rat Model with Surgical Trauma
Published 2015-01-01“…It is hypothesized that central nervous system inflammation induced by systematic inflammation due to surgical trauma plays a critical role in postoperative cognitive dysfunction. …”
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7631
Nonlinear compressive reduced basis approximation for PDE’s
Published 2023-09-01“…Then, we discuss a systematic approach for achieving better performance via a nonlinear reconstruction from the first coordinates of a linear reduced model approximation, thus allowing us to stay in the same “classical” framework of projection-based model reduction. …”
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7632
Rapid Quantitative Analysis of Forest Biomass Using Fourier Transform Infrared Spectroscopy and Partial Least Squares Regression
Published 2016-01-01“…Furthermore, it provides a complete and systematic characterization of this heterogeneous raw material.…”
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7633
A review of Psoralea corylifolia L.: a valuable plant with profound biological significance
Published 2025-01-01“…Furthermore, bibliometric analysis was used to systematically analyze the research hotspots and trends in PCL, which have never been addressed in previous reviews of PCL. …”
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7634
Designer topological-single-atom catalysts with site-specific selectivity
Published 2025-01-01“…This study establishes T-SACs as a promising class of catalysts, offering a systematic framework to address catalytic challenges by defining site characteristics. …”
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7635
Quality of Chatbot Responses to the Most Popular Questions Regarding Erectile Dysfunction
Published 2024-07-01“…ChatGPT was able to answer all the questions systematically, whereas Gemini could not answer two questions. …”
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7636
One Single Amino Acid for Estimation the Content of Total Free Amino Acids in Qingkailing Injection Using High-Performance Liquid Chromatography-Diode Array Detection
Published 2014-01-01“…Particularly, the calculation methods and the robustness of relative correction factors (RCFs) were investigated systematically. No statistically significant difference between these two quantification methods of One for M and classic regression equation was found by the t-test (P = 95%, P>0.05). …”
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7637
Precursor sticking coefficient determination from indented deposits fabricated by electron beam induced deposition
Published 2025-01-01“…An important requirement in this regard is to have access to a methodology that can be used to systematically determine the values for the set of precursor parameters needed for this model. …”
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7638
Children's Use of Electronic Games: Choices of Game Mode and Challenge Levels
Published 2010-01-01“…The purpose of this study was to examine children's electronic game use during conditions in which they had free access to selecting interactive and seated screen-based versions of electronic games and during the interactive versions had free choice in making adjustments to the activity intensity. Methods. We systematically observed 60 Hong Kong primary school children during two 60-minute game sessions while simultaneously recording their game mode choices and physical activity levels using SOFIT (System for Observing Fitness Instruction Time). …”
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7639
Legislation on the Protection of Personal Data: Uncertainty vs Specification
Published 2023-09-01“…They are related to the unification of quantitative characteristics of local acts regulating the personal data processing; systematization of approaches to the interpretation of the personal data as a concept; as well as the interpretation of the characteristics of the personal data subject consent to their processing supplemented by the latest legislative innovations, etc. …”
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7640
Evaluation of the combined toxicity of compound pollutants of azole fungicides to Raphidocelis subcapitata
Published 2025-01-01“…In order to investigate the combined toxicity of compound contaminated azole fungicides on alage. Systematic investigation of Difenoconazole, Penconazole, Metconazole, Tetraconazole, Flutriafol, Fuberidazole, Triflumizole, Terrazole, HyMexazol, 9 azole fungicides as the components of the mixture. …”
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