Systematic surveillance of SARS-CoV-2 reveals dynamics of variant mutagenesis and transmission in a large urban population by Marie-Ming Aynaud, Lauren Caldwell, Khalid N. Al-Zahrani, Seda Barutcu, Kin Chan, Andreea Obersterescu, Abiodun A. Ogunjimi, Min Jin, Kathleen-Rose Zakoor, Shyam Patel, Ron Padilla, Mark C. C. Jen, Princess Mae Veniegas, Nursrin Dewsi, Filiam Yonathan, Lucy Zhang, Amelia Ayson-Fortunato, Analiza Aquino, Paul Krzyzanowski, Jared Simpson, John Bartlett, Ilinca Lungu, Bradly G. Wouters, James M. Rini, Michael Gekas, Susan Poutanen, Laurence Pelletier, Tony Mazzulli, Jeffrey L. Wrana

“…We previously described C19-SPAR-Seq, a high-throughput, next-generation sequencing platform to detect SARS-CoV-2 that we here deployed to systematically profile variant dynamics of SARS-CoV-2 for over 3 years in a large, North American urban environment (Toronto, Canada). …”
Get full text

Timing of mechanical circulatory support in acute myocardial infarction complicated by cardiogenic shock: A systematic review and meta-analysis by Tanawat Attachaipanich, Suthinee Attachaipanich, Kotchakorn Kaewboot

“…This study aimed to evaluate outcomes of pre-percutaneous coronary intervention (PCI) vs post-PCI MCS insertion in AMI patients with cardiogenic shock. Methods: A systematic search using 4 databases, including PubMed, Embase, Web of Science, and Cochrane CENTRAL, was conducted from inception to October 25, 2024. …”
Get full text

Coffee, including caffeinated and decaffeinated coffee, and the risk of hepatocellular carcinoma: a systematic review and dose–response meta-analysis by Paul Roderick, Peter Clive Hayes, Julie Parkes, Ryan Buchanan, Oliver John Kennedy, Jonathan Andrew Fallowfield

“…Objectives To examine the association between coffee, including caffeinated and decaffeinated coffee, with hepatocellular carcinoma (HCC) and assess the influence of HCC aetiology and pre-existing liver disease.Design We performed a systematic review and meta-analysis. We calculated relative risks (RRs) of HCC according to caffeinated and decaffeinated coffee consumption using a random-effects dose–response meta-analysis. …”
Get full text

Circulating Levels of Glial Cell Line-Derived Neurotrophic Factor (GDNF) in Schizophrenia: a systematic review and meta-analysis by Omran Davarinejad, Saeid Komasi, Mohammad-Taher Moradi, Farzaneh Golmohammadi, Maryam Bahrami, Hamed Esmaeil Lashgarian, Masumeh Jalalvand, Sara Hookari, Fatemeh Kazemisafa

“…Therefore, we aimed to calculate a pooled estimate of GDNF levels in patients with SCZ in comparison with healthy controls. Methods A systematic search was performed in PubMed, Scopus, Web of Science, and Science Direct for published studies from the first date available up to 17 June 2024. …”
Get full text

Need to clamp indwelling urinary catheters before removal after different durations: a systematic review and meta-analysis by Xiaoyan Fan, Sumin Ma, Jiayi Gu

“…Objective This meta-analysis aimed to evaluate the effect of bladder training by clamping on bladder urethral function in patients with indwelling urinary catheters used for different durations.Design Systematic review and meta-analysis.Data sources The UpToDate, Cochrane Library, OVID, PubMed, China National Knowledge Infrastructure, CINAHL and Embase were screened from 1 January 2000 to 28 February 2022.Eligibility criteria for selecting studies Randomised controlled trials (RCTs) or quasi-experimental designs comparing the efficacy of bladder training in patients with an indwelling urinary catheter by clamping or free drainage before urinary catheter removal were published in English or Chinese.Data extraction and synthesis Two reviewers independently extracted the data and assessed the quality of studies. …”
Get full text

Evaluation of the Urine POC-CCA Test Accuracy in the Detection of Schistosoma mansoni Infection: A Systematic Review and Meta-Analysis by Getaneh Alemu, Endalkachew Nibret

“…Studies published until May 2022 were searched from PubMed, Google Scholar, and grey literature for systematic review and meta-analysis following the PRISMA guideline. …”
Get full text

Metformin for Treating Gestational Diabetes: What Have We Learned During the Last Two Decades? A Systematic Review by Angeliki Gerede, Ekaterini Domali, Christos Chatzakis, Chrysoula Margioula-Siarkou, Stamatios Petousis, Sofoklis Stavros, Konstantinos Nikolettos, Evanthia Gouveri, Sotirios Sotiriou, Panagiotis Tsikouras, Konstantinos Dinas, Nikolaos Nikolettos, Nikolaos Papanas, Dimitrios G. Goulis, Alexandros Sotiriadis

Get full text

Menstrual disorders and associated factors among rural and tribal adolescent girls in India: A systematic review and meta-analysis by Rashni Chatterjee, Suman Chakrabarty

Subjects: Get full text

Efficacy of preoperative pulmonary rehabilitation in lung cancer patients: a systematic review and meta-analysis of randomized controlled trials by Yalun Guo, Mengdie Pan, Meidi Xiong, Miao Liu, Na Zhu, Haoxu Dong, Chunhua Zhang

Subjects: Get full text

Sustainability of healthcare system improvements, programmes and interventions in acute care settings: protocol for a mixed methods systematic review by Franz E Babl, Sandy Middleton, Julie Cowie, Catherine Wilson, Peter Wilson, Pauline Campbell, Emma Tavender, Lisa Kuhn, Nicola Straiton, Victoria Ramsden, Elizabeth McInnes

“…The aim of this review is to identify facilitators and barriers that influence the delivery of sustained healthcare interventions (eg, integration of clinical guidelines) within adult and paediatric hospital-based acute care settings.Methods and analysis A mixed methods systematic review updating Cowie et al’s (which included studies from 2008 to 2017) previously published systematic review will be conducted. …”
Get full text

Systematic identification and quantification of factors and their interactions with age, sex, and panel wave influencing cognitive function in Korean older adults by Eunmi Kim, Eunmi Kim, Jinkyung Oh, Jinkyung Oh, Jungsoo Gim, Jungsoo Gim, Jungsoo Gim, Iksoo Huh, Iksoo Huh

“…Thus, identifying these factors including their interactions with age, sex, and panel wave and conducting a systematic quantification of their influences on cognitive function are both necessary for developing efficient intervention strategies.MethodsTo identify the influencing factors and their interactions, we applied a systematic stepwise variable selection using 2,535 community-dwelling older adults who participated in the Korean Longitudinal Study of Aging from Wave 5 (2014) to Wave 8 (2020). …”
Get full text

The Effect of TNF-α on CHD and the Relationship between TNF-α Antagonist and CHD in Rheumatoid Arthritis: A Systematic Review by Yezhou Qian, Menghui Mao, Feige Nian

Get full text

Effect of Sodium Hypochlorite Concentration on the Outcome of Full Pulpotomy in Mature Permanent Teeth with Irreversible Pulpitis – A Systematic Review by Aakriti Saini, Amandeep Kaur, Sidhartha Sharma, Vijay Kumar, Amrita Chawla, Ajay Logani

Get full text

Impact of antiparasitic therapy on cardiovascular outcomes in chronic Chagas disease. A systematic review and meta-analysisResearch in context by Anis Rassi, Jr, Alyssa Grimshaw, Ashwin Sarwal, Ranjit Sah, Sangam Shah, Nelson I. Agudelo Higuita, Fabio Mahamed Rassi, Michaele Francesco Corbisiero, Hannah M. Kyllo, Jordan Stellern, Samantha Kaplan, Luis A. Marcos, Edgar A. Ramírez-García, Martin Casapia, Peter Hotez, Maria Elena Bottazzi, Shital Patel, Carlos Franco-Paredes, José Antonio Marin-Neto, Andrés F. Henao-Martínez

“…Methods: We performed a systematic review and meta-analysis of studies reporting the cardiovascular outcomes of antitrypanosomal therapy in patients with chronic Chagas disease. …”
Get full text

Is there a role for acromioclavicular (AC) joint capsular repair and reconstruction in high-grade AC separations? A systematic review by Al-Achraf Khoriati, Tony Antonios, Zien Alabdin Fozo, Aliya Choudhury, Magnus Arnander, Eyiyemi Pearse, Duncan Tennent

“…Methods: This is a systematic review of biomechanical and clinical studies that describe AC reconstructive or reparative techniques. …”
Get full text

Prognostic value of systemic immune-inflammation index for patients undergoing radical prostatectomy: a systematic review and meta-analysis by Zhan Chen, Yao Zhang, Wei Chen

“…However, the quality of the evidence provided by this study was low.Systematic Review Registrationhttps://www.crd.york.ac.uk/PROSPERO/, identifier CRD42024558431.…”
Get full text

A National Baseline Prevalence Survey of Schistosomiasis in the Philippines Using Stratified Two-Step Systematic Cluster Sampling Design by Lydia Leonardo, Pilarita Rivera, Ofelia Saniel, Elena Villacorte, May Antonnette Lebanan, Bobby Crisostomo, Leda Hernandez, Mario Baquilod, Edgardo Erce, Ruth Martinez, Raman Velayudhan

“…For the first time in the country, a national baseline prevalence survey using a well-defined sampling design such as a stratified two-step systematic cluster sampling was conducted in 2005 to 2008. …”
Get full text

Smartphone applications for physical activity and sedentary behaviour change in people with cardiovascular disease: A systematic review and meta-analysis. by Kacie Patterson, Rachel Davey, Richard Keegan, Nicole Freene

“…<h4>Background</h4>Smartphone applications provide new opportunities for secondary prevention healthcare. This systematic review and meta-analysis aimed to determine if smartphone applications are effective at changing physical activity and sedentary behaviour in people with cardiovascular disease.…”
Get full text

Vitamin D Supplementation Ameliorates Metabolic Dysfunction in Patients with PCOS: A SystematicReview of RCTs and Insight into the Underlying Mechanism by Shan Guo, Reshef Tal, Haoyu Jiang, Tao Yuan, Ying Liu

“…The effect of vitamin D supplementation alone on women with PCOS was compared with administration of placebo. The systematic review and meta-analysis protocol was registered in the International Prospective Register of Systematic Reviews (Prospero) as number CRD42020157444. …”
Get full text

Development and predictors of bipolar disorder in children and adolescents with depressive disorders: a systematic review, meta-analysis, and meta-regression by Gonzalo Salazar de Pablo, Violeta Perez-Rodriguez, Javier de Otazu Olivares, Javier Camacho-Rubio, Aditya Sharma, Ana Catalán, Josefien Breedvelt, Claudia Aymerich, Mihai Pop, Carmen Moreno, Ian Kelleher, Jane Anderson, Paolo Fusar-Poli, Christoph U Correll, Allan H. Young

“…We aimed to quantitatively examine the risk of developing BD from depressive disorders and identify factors which moderate this development. Methods In this systematic review and meta-analysis (PROSPERO:CRD42023431301), PubMed and Web-of-Science databases were searched for longitudinal studies reporting the percentage of C&A with ICD/DSM-defined depressive disorders who developed BD during follow-up. …”
Get full text