Synaptic Paths to Neurodegeneration: The Emerging Role of TDP-43 and FUS in Synaptic Functions by Shuo-Chien Ling

“…Intriguingly, many of the RNA targets of TDP-43 and FUS are involved in synaptic transmission and plasticity, indicating that synaptic dysfunction could be an early event contributing to motor and cognitive deficits in ALS and FTD. …”
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Calcineurin, Synaptic Plasticity, and Memory by Carl Weitlauf, Danny Winder

“…A long-held hypothesis in neuroscience holds that learning and memory mechanisms involve lasting changes in synaptic weights. Multiple mechanisms for producing such changes exist, of which NMDA-receptor–dependent long-term potentiation (LTP) is the most widely studied. …”
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Synaptic motility and functional stability in the whisker cortex by Nimrod Sherf, Maoz Shamir

“…The high motility of synaptic weights raises the question of how the brain can retain its functionality in the face of constant synaptic remodeling. …”
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GABA Metabolism and Transport: Effects on Synaptic Efficacy by Fabian C. Roth, Andreas Draguhn

“…In addition, inhibitory synaptic signals contribute crucially to the organization of spatiotemporal patterns of network activity, especially during coherent oscillations. …”
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Role of MicroRNA in Governing Synaptic Plasticity by Yuqin Ye, Hongyu Xu, Xinhong Su, Xiaosheng He

“…Increasing evidence suggests that quite a few specific miRNAs play important roles in various respects of synaptic plasticity including synaptogenesis, synaptic morphology alteration, and synaptic function modification. …”
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Structural, Synaptic, and Epigenetic Dynamics of Enduring Memories by Ossama Khalaf, Johannes Gräff

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Molecular Mechanisms of Oxytocin Signaling at the Synaptic Connection by Jan Bakos, Annamaria Srancikova, Tomas Havranek, Zuzana Bacova

“…The ability of oxytocin to modulate neurogenesis, synaptic plasticity, and certain parameters of cytoskeletal arrangement is discussed in the present review.…”
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Synaptic Cell Adhesion Molecules in Alzheimer’s Disease by Iryna Leshchyns’ka, Vladimir Sytnyk

“…Alzheimer’s disease (AD) is a neurodegenerative brain disorder associated with the loss of synapses between neurons in the brain. Synaptic cell adhesion molecules are cell surface glycoproteins which are expressed at the synaptic plasma membranes of neurons. …”
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CGRP and Adrenomedullin Modulate Synaptic Transmission in Purkinje Cells by H. Cater, D. Poyner, N. Hartell

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Molecular mechanisms of autism as a form of synaptic dysfunction by E. A. Trifonova, T. M. Khlebodarova, N. E. Gruntenko

“…The most prominent forms of synaptic plasticity are accompanied by changes in protein biosynthesis, both in neuron body and in dendrites. …”
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Dopaminergic Suppression of Synaptic Transmission in the Lateral Entorhinal Cortex by Douglas A. Caruana, C. Andrew Chapman

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Synaptic Plasticity Changes: Hallmark for Neurological and Psychiatric Disorders by Giuseppina Martella, Paola Bonsi, Steven W. Johnson, Angelo Quartarone

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Hepatocyte Growth Factor in Synaptic Plasticity and Alzheimer's Disease by Shiv K. Sharma

“…This review describes the role of HGF in hippocampal neurons, synaptic plasticity, and the memory impairment condition, Alzheimer's disease.…”
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Microglia and Spinal Cord Synaptic Plasticity in Persistent Pain by Sarah Taves, Temugin Berta, Gang Chen, Ru-Rong Ji

“…In this review, we discuss the recent findings illustrating the importance of microglial mediators in regulating synaptic plasticity of the excitatory and inhibitory pain circuits in the spinal cord, leading to enhanced pain states. …”
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Synaptic Plasticity and Neurological Disorders in Neurotropic Viral Infections by Venkata Subba Rao Atluri, Melissa Hidalgo, Thangavel Samikkannu, Kesava Rao Venkata Kurapati, Madhavan Nair

“…In this review, we have discussed the neurotropic viruses, which play a major role in altered synaptic plasticity and neurological disorders.…”
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In Sickness and in Health: Perineuronal Nets and Synaptic Plasticity in Psychiatric Disorders by Harry Pantazopoulos, Sabina Berretta

“…In the context of the “quadripartite” synapse concept, that is, the functional unit composed of the pre- and postsynaptic terminals, glial processes, and ECM, and of the role that PNNs and ECM molecules play in regulating synaptic functions and plasticity, these findings resonate with one of the most well-replicated aspects of the pathology of psychiatric disorders, that is, synaptic abnormalities. …”
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Pinpointing Synaptic Loss Caused by Alzheimer’s Disease with fMRI by Adam M. Brickman, Scott A. Small, Adam Fleisher

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Behavioral Tagging: A Translation of the Synaptic Tagging and Capture Hypothesis by Diego Moncada, Fabricio Ballarini, Haydée Viola

“…Similar molecular machinery is activated in neurons following an electrical stimulus that induces synaptic changes and after learning sessions that trigger memory formation. …”
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Synaptic Wnt/GSK3β Signaling Hub in Autism by Mario O. Caracci, Miguel E. Ávila, Giancarlo V. De Ferrari

“…The convergence of these variants in networks of genes associated with synaptic function warrants the study of cell signaling pathways involved in the regulation of the synapse. …”
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Cortical Circuitry and Synaptic Dysfunctions in Alzheimer’s Disease and Other Dementias by Federico Ranieri, Alberto Benussi, Mariagiovanna Cantone, Florinda Ferreri, Javier Márquez-Ruiz

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