Ripples Make Waves: Binding Structured Activity and Plasticity in Hippocampal Networks by Josef H. L. P. Sadowski, Matthew W. Jones, Jack R. Mellor

“…Such events facilitate memory formation by optimising the conditions for synaptic plasticity to occur between contingent neural elements. …”
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Developmental and Activity Dependent Regulation of Ionotropic Glutamate Receptors at Synapses by Elek Molnar, John T.R. Isaac

“…Here we discuss the evidence that these basic mechanisms are used during developmental synaptic plasticity.…”
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Direct engulfment of synapses by overactivated microglia due to cadmium exposure and the protective role of Nrf2 by Siyao Li, Mingdan You, Chengjie Chen, Jingqi Fu, Yuanyuan Xu, Jingbo Pi, Yi Wang

“…We aimed to explore the role of microglia in Cd-induced synaptic damages at environmentally relevant doses and whether microglia directly engulf synaptic structures. …”
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The Contribution of α-Synuclein Spreading to Parkinson’s Disease Synaptopathy by Francesca Longhena, Gaia Faustini, Cristina Missale, Marina Pizzi, PierFranco Spano, Arianna Bellucci

“…In sporadic PD, the most common age-related neurodegenerative movement disorder, nigrostriatal dopaminergic deficits are responsible for the onset of motor symptoms that have been related to α-synuclein deposition at synaptic sites. Indeed, α-synuclein accumulation can impair synaptic dopamine release and induces the death of nigrostriatal neurons. …”
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Chronic Rapamycin Prevents Electrophysiological and Morphological Alterations Produced by Conditional Pten Deletion in Mouse Cortex by Jason S. Hauptman, Joseph Antonios, Gary W. Mathern, Michael S. Levine, Carlos Cepeda

“…CPNs from normal mice chronically treated with rapamycin, compared with CPNs from naïve mice, showed reduced capacitance and time constant, increased input resistance, and changes in inhibitory synaptic inputs, consistent with increased pre-synaptic GABA release. …”
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Dopaminergic Modulation of Striatal Inhibitory Transmission and Long-Term Plasticity by Elizabeth Nieto Mendoza, Elizabeth Hernández Echeagaray

“…Our results showed that low and high DA concentrations mainly reduced the amplitude of inhibitory synaptic response; however detailed analysis of the D1 and D2 participation in this modulation displayed a wide variability in synaptic response. …”
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Spines, Plasticity, and Cognition in Alzheimer's Model Mice by Tara Spires-Jones, Shira Knafo

“…Here, we review work on transgenic AD models that investigate the degeneration of dendritic spine structure, synaptic function, and cognition. Together, these data support a model of AD pathogenesis in which soluble Aβ initiates synaptic dysfunction and loss, as well as pathological changes in tau, which contribute to both synaptic and neuronal loss. …”
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Cellular Signal Mechanisms of Reward-Related Plasticity in the Hippocampus by Masako Isokawa

“…Consequently, there is an intense interest in the mechanisms that underline learning and memory. Synaptic plasticity has been hypothesized to be the neuronal substrate for learning. …”
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Glia and TRPM2 Channels in Plasticity of Central Nervous System and Alzheimer’s Diseases by Jing Wang, Michael F. Jackson, Yu-Feng Xie

“…Synaptic plasticity refers to the ability of neurons to strengthen or weaken synaptic efficacy in response to activity and is the basis for learning and memory. …”
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Plasticity of Neuron-Glial Transmission: Equipping Glia for Long-Term Integration of Network Activity by Wayne Croft, Katharine L. Dobson, Tomas C. Bellamy

“…The capacity of synaptic networks to express activity-dependent changes in strength and connectivity is essential for learning and memory processes. …”
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Brain Plasticity and Cell Competition: Immediate Early Genes Are the Focus by Pavel P. Tregub, Yulia K. Komleva, Maria V. Kukla, Anton S. Averchuk, Anna S. Vetchinova, Natalia A. Rozanova, Sergey N. Illarioshkin, Alla B. Salmina

“…It includes several mechanisms of synaptic and extrasynaptic changes, neurogenesis, and the formation and elimination of synapses. …”
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Physiological Properties of Supragranular Cortical Inhibitory Interneurons Expressing Retrograde Persistent Firing by Barbara Imbrosci, Angela Neitz, Thomas Mittmann

“…The somatodendritic compartment receives and integrates synaptic inputs while the axon relays relevant synaptic information in form of action potentials (APs) across long distance. …”
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Large-scale high uniform optoelectronic synapses array for artificial visual neural network by Fanqing Zhang, Chunyang Li, Zhicheng Chen, Haiqiu Tan, Zhongyi Li, Chengzhai Lv, Shuai Xiao, Lining Wu, Jing Zhao

“…Various synaptic plasticity behaviors have been achieved owing to the switchable electronic storage performance. …”
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Emerging Roles of Synapse Organizers in the Regulation of Critical Periods by Adema Ribic, Thomas Biederer

“…Experience-dependent regulation of synaptic strength during these periods establishes circuit functions that are stabilized as critical period plasticity wanes. …”
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Investigation of Neuron Latency Modulated by Bilateral Inferior Collicular Interactions Using Whole-Cell Patch Clamp Recording in Brain Slices by Jinzhe Ma, Yangyang Han, Yiting Yao, Huimei Wang, Mengxia Chen, Ziying Fu, Qicai Chen, Jia Tang

“…We used whole-cell patch clamp recordings to assess synaptic responses in isolated brain slices of Kunming mice. …”
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Presynaptic Ionotropic Receptors Controlling and Modulating the Rules for Spike Timing-Dependent Plasticity by Matthijs B. Verhoog, Huibert D. Mansvelder

“…Furthermore, we will discuss how interaction between different types of ionotropic receptors may create “timing” windows during which particular timing rules lead to synaptic changes.…”
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GSK-3β at the Intersection of Neuronal Plasticity and Neurodegeneration by Tomasz Jaworski, Ewa Banach-Kasper, Katarzyna Gralec

“…Here, we provide an overview of how GSK-3β is regulated in physiological synaptic plasticity and how aberrant GSK-3β activity contributes to the development of dysfunctional synaptic plasticity in neuropsychiatric and neurodegenerative disorders.…”
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Aging Alters Olfactory Bulb Network Oscillations and Connectivity: Relevance for Aging-Related Neurodegeneration Studies by A. Ahnaou, D. Rodriguez-Manrique, S. Embrechts, R. Biermans, N. V. Manyakov, S. A. Youssef, W. H. I. M. Drinkenburg

“…The aging process eventually cause a breakdown in critical synaptic plasticity and connectivity leading to deficits in memory function. …”
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14-3-3 Proteins in Glutamatergic Synapses by Jiajing Zhang, Yi Zhou

“…A key challenge for the future is to delineate the 14-3-3-dependent molecular pathways involved in regulating synaptic functions.…”
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Thy1-YFP: an effective tool for single cell tracing from neuronal progenitors to mature functionally active neurons by Ante Plećaš, Katarina Kapuralin, Leonarda Grandverger, Dinko Mitrečić, Ivan Alić

“…Expression of synaptic markers were increased during differentiation in vitro. …”
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