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The Cul3 ubiquitin ligase engages Insomniac as an adaptor to impact sleep and synaptic homeostasis.
Published 2025-01-01“…Here we implicate Insomniac (Inc), a conserved protein required for normal sleep and synaptic homeostasis in Drosophila, as a Cul3 adaptor. …”
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62
Wave fronts in neuronal fields with nonlocalpost-synaptic axonal connections and delayed nonlocal feedbackconnections
Published 2010-03-01“…The kernel in thefeedback channel is assumed to be a standard non-local one, while forthe kernel in the synaptic coupling, four types are considered.The main concern is the existence of travelling wave front. …”
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63
Intrusion detection using synaptic intelligent convolutional neural networks for dynamic Internet of Things environments
Published 2025-01-01Subjects: Get full text
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64
Large and Small Dendritic Spines Serve Different Interacting Functions in Hippocampal Synaptic Plasticity and Homeostasis
Published 2016-01-01“…The laying down of memory requires strong stimulation resulting in specific changes in synaptic strength and corresponding changes in size of dendritic spines. …”
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65
Comparative Study of Metaheuristics for the Curve-Fitting Problem: Modeling Neurotransmitter Diffusion and Synaptic Receptor Activation
Published 2015-01-01“…Based on the results of this analysis, we propose a set of mathematical equations and a methodology, adequate for modeling several aspects of biochemical synaptic behavior.…”
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66
Exercise‐Activated mPFC Tri‐Synaptic Pathway Ameliorates Depression‐Like Behaviors in Mouse
Published 2025-01-01Subjects: Get full text
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67
Tripchlorolide May Improve Spatial Cognition Dysfunction and Synaptic Plasticity after Chronic Cerebral Hypoperfusion
Published 2019-01-01“…Low cerebral blood flow (CBF) during CCH leads to disturbances in the homeostasis of hemodynamics and energy metabolism, which in turn results in oxidative stress, astroglia overactivation, and synaptic protein downregulation. These events contribute to synaptic plasticity and cognitive dysfunction after CCH. …”
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68
MCU expression in hippocampal CA2 neurons modulates dendritic mitochondrial morphology and synaptic plasticity
Published 2025-02-01Subjects: Get full text
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69
MicroRNA-33 regulates the synaptic plasticity-related gene ARC in temporal lobe epilepsy
Published 2025-01-01Get full text
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70
Ferroelectric Transistor-Based Synaptic Crossbar Arrays: The Impact of Ferroelectric Thickness and Device-Circuit Interactions
Published 2024-01-01“…First, based on a physics-based model of multidomain FeFETs calibrated to experiments, we analyze the impact of <inline-formula> <tex-math notation="LaTeX">$T_{\text {FE}}$ </tex-math></inline-formula> on the characteristics of FeFETs as synaptic devices, highlighting the connections between the multidomain physics and the synaptic attributes. …”
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71
S100A9 protein activates microglia and stimulates phagocytosis, resulting in synaptic and neuronal loss
Published 2025-03-01“…At lower concentrations, 10–100 nM S100A9 induced synaptic loss in the cultures. Depletion of microglia from the cultures prevented S100A9-induced neuronal and synaptic loss, indicating that neuronal and synaptic loss was mediated by microglia. …”
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72
Electroacupuncture Increases the Hippocampal Synaptic Transmission Efficiency and Long-Term Plasticity to Improve Vascular Cognitive Impairment
Published 2022-01-01“…EA at GV20 and GV24 acupoints increased the basic synaptic transmission efficiency and synaptic plasticity of the hippocampal CA3–CA1 circuit, thereby improving learning and memory ability in rats with VCI.…”
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73
Nerve root magnetic stimulation regulates the synaptic plasticity of injured spinal cord by ascending sensory pathway
Published 2025-12-01Subjects: Get full text
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74
Low-power artificial neuron networks with enhanced synaptic functionality using dual transistor and dual memristor.
Published 2025-01-01“…Recent literature has proposed memristors as a promising option for synaptic implementation. In contrast, implementing memristive circuitry through neuron hardware presents significant challenges and is a relevant research topic. …”
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75
Synaptic Structure and Function in the Mouse Somatosensory Cortex during Chronic Pain: In Vivo Two-Photon Imaging
Published 2012-01-01“…Long-term in vivo two-photon imaging studies have shown that some postsynaptic dendritic spines in the adult cortex are rapidly eliminated or newly generated, in response to altered sensory input or synaptic activity, resulting in experience/activity-dependent rewiring of neuronal circuits. …”
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76
Advances in synaptic PET imaging and intervention with synapse-targeted small-molecular drugs for dementia diagnosis and therapy
Published 2025-01-01Subjects: “…Synaptic density imaging…”
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77
CircSATB2 modulates fear extinction memory via Robo3-driven synaptic plasticity
Published 2025-01-01Subjects: Get full text
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78
From Abnormal Hippocampal Synaptic Plasticity in Down Syndrome Mouse Models to Cognitive Disability in Down Syndrome
Published 2012-01-01“…At the core of cognitive processes is the phenomenon of synaptic plasticity, a functional change in the strength at points of communication between neurons. …”
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79
Effect of Chronic Morphine Consumption on Synaptic Plasticity of Rat’s Hippocampus: A Transmission Electron Microscopy Study
Published 2013-01-01“…In the present study, we investigated the effects of chronic morphine consumption on synaptic plasticity, postsynaptic density thickness, and synaptic curvatures of hippocampus CA1 area of rats. …”
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Cellular Cholesterol Loss Impairs Synaptic Vesicle Mobility via the CAMK2/Synapsin-1 Signaling Pathway
Published 2025-01-01Subjects: Get full text
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