Potential Role of Synaptic Activity to Inhibit LTD Induction in Rat Visual Cortex by Matthew R. Stewart, Hans C. Dringenberg

“…Long-term depression (LTD), a widely studied form of activity-dependent synaptic plasticity, is typically induced by prolonged low-frequency stimulation (LFS). …”
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Modulating synaptic plasticity with metal−organic framework for information-filterable artificial retina by Seongchan Kim, Ohchan Kwon, Seonkwon Kim, Seonmin Jang, Seungho Yu, Choong Hoo Lee, Yoon Young Choi, Soo Young Cho, Ki Chul Kim, Cunjiang Yu, Dae Woo Kim, Jeong Ho Cho

“…Here, we present an information-filterable artificial retina system that integrates artificial synapses with a signal-integration device for signal perception and processing with attention. The synaptic weight modulation is rendered through metal–organic framework (MOF) layers, where distinct short-term and long-term properties are predominantly determined by MOF’s pore diameter and functionality. …”
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Protocol for generating human assembloids to investigate thalamocortical and corticothalamic synaptic transmission and plasticity by Anjana Nityanandam, Mary H. Patton, Ildar T. Bayazitov, Kyle D. Newman, Kristen T. Thomas, Stanislav S. Zakharenko

“…We detail the steps for using whole-cell patch-clamp electrophysiology to investigate the properties of synaptic transmission and synaptic plasticity in this model system.For complete details on the use and execution of this protocol, please refer to Patton et al.1 : Publisher’s note: Undertaking any experimental protocol requires adherence to local institutional guidelines for laboratory safety and ethics.…”
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Tau oligomers impair memory and synaptic plasticity through the cellular prion protein by Claudia Balducci, Franca Orsini, Milica Cerovic, Marten Beeg, Beatrice Rocutto, Letizia Dacomo, Antonio Masone, Eleonora Busani, Ilaria Raimondi, Giada Lavigna, Po-Tao Chen, Susanna Leva, Laura Colombo, Chiara Zucchelli, Giovanna Musco, Nicholas M. Kanaan, Marco Gobbi, Roberto Chiesa, Luana Fioriti, Gianluigi Forloni

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Synaptic behaviour in ZnO–rGO composites thin film memristor by G.M. Khanal, S. Acciarito, G.C. Cardarilli, A. Chakraborty, L.D. Nunzio, R. Fazzolari, A. Cristini, M. Re, G. Susi

Subjects: “…synaptic behaviour…”
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Dendritic growth and synaptic organization from activity-independent cues and local activity-dependent plasticity by Jan H Kirchner, Lucas Euler, Ingo Fritz, André Ferreira Castro, Julijana Gjorgjieva

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KV7 Channels Regulate Firing during Synaptic Integration in GABAergic Striatal Neurons by M. Belén Pérez-Ramírez, Antonio Laville, Dagoberto Tapia, Mariana Duhne, Esther Lara-González, José Bargas, Elvira Galarraga

“…Therefore, an important question is whether muscarinic G-protein coupled receptors and their signaling cascades are fast enough to intervene during synaptic responses to regulate synaptic integration and firing. …”
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Neurogranin in Alzheimer's Disease: Roles in synaptic function, pathology, and potential as a diagnostic biomarker by Rajkumar Bavaharini, Chaitanya Sree Somala, Konda Mani Saravanan, Thirunavukarasou Anand

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Bacterial cytolysin during meningitis disrupts the regulation of glutamate in the brain, leading to synaptic damage. by Carolin Wippel, Jana Maurer, Christina Förtsch, Sabrina Hupp, Alexandra Bohl, Jiangtao Ma, Timothy J Mitchell, Stephanie Bunkowski, Wolfgang Brück, Roland Nau, Asparouh I Iliev

“…Here, we demonstrate selective synaptic loss within the superficial layers of the frontal neocortex of post-mortem brain samples from individuals with pneumococcal meningitis. …”
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Neurons with larval synaptic targets pioneer the later nervous system in the annelid Malacoceros fuliginosus by Anna Seybold, Anna Seybold, Suman Kumar, Suman Kumar, Sharat Chandra Tumu, Harald Hausen, Harald Hausen

“…Although they are laying the paths for the later adult nervous system, they also make synaptic contact with the main ciliated ring of the larva. …”
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Inhibition of DNA Methylation Impairs Synaptic Plasticity during an Early Time Window in Rats by Pablo Muñoz, Carolina Estay, Paula Díaz, Claudio Elgueta, Álvaro O. Ardiles, Pablo A. Lizana

“…Although the importance of DNA methylation-dependent gene expression to neuronal plasticity is well established, the dynamics of methylation and demethylation during the induction and expression of synaptic plasticity have not been explored. Here, we combined electrophysiological, pharmacological, molecular, and immunohistochemical approaches to examine the contribution of DNA methylation and the phosphorylation of Methyl-CpG-binding protein 2 (MeCP2) to synaptic plasticity. …”
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Synaptic enrichment and dynamic regulation of the two opposing dopamine receptors within the same neurons by Shun Hiramatsu, Kokoro Saito, Shu Kondo, Hidetaka Katow, Nobuhiro Yamagata, Chun-Fang Wu, Hiromu Tanimoto

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P2Y Receptors in Synaptic Transmission and Plasticity: Therapeutic Potential in Cognitive Dysfunction by Segundo J. Guzman, Zoltan Gerevich

“…We show that P2Y receptors inhibit the release of neurotransmitters, modulate voltage- and ligand-gated ion channels, and differentially influence the induction of synaptic plasticity in the prefrontal cortex, hippocampus, and cerebellum. …”
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NMDA Receptor Subunits Change after Synaptic Plasticity Induction and Learning and Memory Acquisition by María Verónica Baez, Magalí Cecilia Cercato, Diana Alicia Jerusalinsky

“…NMDA ionotropic glutamate receptors (NMDARs) are crucial in activity-dependent synaptic changes and in learning and memory. NMDARs are composed of two GluN1 essential subunits and two regulatory subunits which define their pharmacological and physiological profile. …”
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Effects of Treadmill Exercise on Hippocampal Synaptic Plasticity and Expression of Related Proteins in Aging Mice by WANG Sinuo, CAO Yajun, XIANG Qing, YAN Jiamin, LIN Yanting, ZHUANG Yueyang, GUO Xiaoqin, LIU Weilin

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Localization of Presynaptic Plasticity Mechanisms Enables Functional Independence of Synaptic and Ectopic Transmission in the Cerebellum by Katharine L. Dobson, Tomas C. Bellamy

“…Stimulation of parallel fibre inputs at 16 Hz evoked LTP of synaptic transmission, but LTD of ectopic transmission. …”
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Proteomic Analysis Reveals the Vital Role of Synaptic Plasticity in the Pathogenesis of Temporal Lobe Epilepsy by Xu Qian, Ji-Qiang Ding, Xin Zhao, Xin-Wen Sheng, Zhao-Rui Wang, Qi-xing Yang, Jing-Jun Zheng, Jia-Gui Zhong, Teng-Yue Zhang, Shu-Qiao He, Wei-Dong Ji, Wei Li, Mei Zhang

“…Consequently, the synaptic plasticity-related proteins and synaptic structure were investigated to verify it. …”
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Nonapoptotic caspase-3 guides C1q-dependent synaptic phagocytosis by microglia by Megumi Andoh, Natsuki Shinoda, Yusuke Taira, Tasuku Araki, Yuka Kasahara, Haruki Takeuchi, Masayuki Miura, Yuji Ikegaya, Ryuta Koyama

“…However, here we show that nonapoptotic activation of caspase-3 at presynapses drives microglial synaptic phagocytosis. Real-time observation and spatiotemporal manipulation of synaptic caspase-3 in the newly established, mouse-derived culture system demonstrate that increased neuronal activity triggers localized presynaptic caspase-3 activation, facilitating synaptic tagging by complements. …”
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Mouse-derived Synaptosomes Trypsin Cleavage Assay to Characterize Synaptic Protein Sub-localization by Jasmeet Shergill, Domenico Azarnia Tehran

“…Each neuron forms numerous synaptic connections, consisting of presynaptic and postsynaptic terminals. …”
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Neuronal BDNF Signaling Is Necessary for the Effects of Treadmill Exercise on Synaptic Stripping of Axotomized Motoneurons by Joey Krakowiak, Caiyue Liu, Chandana Papudesu, P. Jillian Ward, Jennifer C. Wilhelm, Arthur W. English

“…The withdrawal of synaptic inputs from the somata and proximal dendrites of spinal motoneurons following peripheral nerve injury could contribute to poor functional recovery. …”
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