Auditory Stimulation Dishabituates Olfactory Responses via Noradrenergic Cortical Modulation by Jonathan J. Smith, Kiseko Shionoya, Regina M. Sullivan, Donald A. Wilson

“…In the mammalian olfactory system, metabotropic glutamate receptor mediated synaptic depression of cortical afferents underlies short-term habituation to odors. …”
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Proton-electron coupling and mixed conductivity in a hydrogen-bonded coordination polymer by Minju Park, Huiyeong Ju, Joohee Oh, Kwangmin Park, Hyunseob Lim, Seok Min Yoon, Intek Song

“…We demonstrate the practical implications of this mechanism by examining the humidity-dependent synaptic plasticity of Ni-BAND, showcasing how MPECs can expand into traditional MIEC applications while leveraging their unique proton-mediated advantages.…”
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Reconciling Homeostatic and Use-Dependent Plasticity in the Context of Somatosensory Deprivation by John J. Orczyk, Preston E. Garraghty

“…Plasticity is induced by changes in the strengths of synaptic inputs, as well as changes in temporal correlation of neuronal activity. …”
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From hypoxic pockets to daily routines: linking brain oxygenation and cognitive resilience by Dian Jiao

“…These transient oxygen-deprived microenvironments play a pivotal role in neurovascular coupling, synaptic plasticity, and angiogenesis, processes crucial for maintaining cognitive resilience and neuronal health. …”
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Sex-based differences in the long-term fate of hippocampal neurons born after a traumatic brain injury by Hannah C. Downing, Hannah C. Downing, Ashley B. Glover, Jessica E. Gebhardt, Jessica E. Gebhardt, Katherine L. Thompson, Kathryn E. Saatman, Kathryn E. Saatman, Kathryn E. Saatman

“…Neurons born after injury extended axons which formed synaptic terminals within the CA3 region. Numbers of mossy fiber boutons were significantly decreased in injured males compared to naïve males or to injured females. …”
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Control of Linear-Threshold Brain Networks via Reservoir Computing by Michael McCreesh, Jorge Cortes

“…We first formally design open- and closed-loop controllers that achieve reference tracking under suitable conditions on the synaptic connectivity. Given the impracticality of evaluating closed-form control signals, particularly with growing network complexity, we provide a framework where a reservoir of a larger size than the network is trained to drive the activity to the desired pattern. …”
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Cellular Programming and Reprogramming: Sculpting Cell Fate for the Production of Dopamine Neurons for Cell Therapy by Julio C. Aguila, Eva Hedlund, Rosario Sanchez-Pernaute

“…Because synapses are highly specific, only neurons with this precise identity will contribute, upon transplantation, to the synaptic reconstruction of the dorsal striatum. Thus, understanding the developmental cell program of the mesostriatal dopamine neurons is critical for the identification of the extrinsic signals and cell-intrinsic factors that instruct and, ultimately, determine cell identity. …”
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Emerging Roles of BAI Adhesion-GPCRs in Synapse Development and Plasticity by Joseph G. Duman, Yen-Kuei Tu, Kimberley F. Tolias

“…The sites of most excitatory synapses in the brain, dendritic spines, undergo rapid remodeling that is important for neural circuit formation and synaptic plasticity. Abnormalities in synapse and spine formation and plasticity are associated with a broad range of brain disorders, including intellectual disabilities, autism spectrum disorders (ASD), and schizophrenia. …”
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Catecholaminergic dysfunction drives postural and locomotor deficits in a mouse model of spinal muscular atrophy by John G. Pagiazitis, Nicolas Delestrée, Leonie Sowoidnich, Nandhini Sivakumar, Christian M. Simon, Athanasios Chatzisotiriou, Maria Albani, George Z. Mentis

“…These findings uncover the synaptic and cellular mechanisms responsible for the postural and motor symptoms in SMA and identify catecholaminergic neuromodulation as a potential therapeutic target.…”
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Platelets tune fear memory in mice by Stefano Garofalo, Alessandro Mormino, Letizia Mazzarella, Germana Cocozza, Arianna Rinaldi, Erika Di Pietro, Maria Amalia Di Castro, Eleonora De Felice, Laura Maggi, Giuseppina Chece, Diego Andolina, Rossella Ventura, Donald Ielpo, Roberto Piacentini, Myriam Catalano, Lucia Stefanini, Cristina Limatola

“…Both NK cells and platelet depletion reduce the activation of hippocampal inhibitory neurons and increase the long-term potentiation of synaptic transmission. Understanding the role of platelets in the modulation of neuro-immune interactions offers additional tools for the definition of the molecular and cellular elements involved in the growing field of brain-body communication.…”
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Self-Organizing Mapping Neural Network Implementation Based on 3-D NAND Flash for Competitive Learning by Anyi Zhu, Lei Jin, Wen Zhou, Tianchun Ye, Zongliang Huo

“…It is experimentally demonstrated that the differential pair in 3D NAND flash array possesses superior characteristics for neuromorphic computing during increasing and decreasing synaptic weight. Using the 3D NAND-based SOM, a competitive learning neural network is established and used for the unsupervised classification of a set of Gaussian distribution data points. …”
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Visual experience orthogonalizes visual cortical stimulus responses via population code transformation by Samuel W. Failor, Matteo Carandini, Kenneth D. Harris

“…The strength of the transformation varies across trials, suggesting a dynamic circuit mechanism rather than static synaptic plasticity. The transformation results in sparsening and orthogonalization of population codes for task stimuli. …”
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Daily oscillation of the excitation/inhibition ratio is disrupted in two mouse models of autism by Michelle C.D. Bridi, Nancy Luo, Grace Kim, Benjamin J. Menarchek, Rachel A. Lee, Bryan Rodriguez, Daniel Severin, Christian Wesselborg, Caroline O’Ferrall, Ruchit Patel, Sarah Bertrand, Sujatha Kannan, Alfredo Kirkwood, Cristian Moreno, Altagracia Contreras

“…Phenotypes in both models associate with differences the timing of excitatory and inhibitory synaptic transmission and endocannabinoid signaling compared to wild type mice, but not with altered sleep. …”
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Ethical Implications in the Use of Embryonic and Adult Neural Stem Cells by Rodrigo Ramos-Zúñiga, Oscar González-Pérez, Ana Macías-Ornelas, Vivian Capilla-González, Alfredo Quiñones-Hinojosa

“…We have just started to get a glimpse of the structural and functional role of neural stem cells in differentiation and migration processes, the origin of synaptic networks, and subsequent readjustments in specific circuits. …”
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PLGA scaffold combined with MSCs transplantation improved neural function and brain tissue structure in rats with traumatic brain injury by Na Xu, Zihuan Sun, Weikang Guan, Yiming Liu, Yun Gao, Chaoxian Yang

“…Furthermore, compared to PLGA transplantation alone, PLGA+MSCs transplantation further reduced brain injury and cell apoptosis, promoted neuron survival, and improved synaptic plasticity. Overall, the adhesion of MSCs to PLGA can enhance the therapeutic efficacy of PLGA in rats following TBI.…”
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Cholecystokinin facilitates the formation of long-term heterosynaptic plasticity in the distal subiculum by Fengwen Huang, Abdul Baset, Stephen Temitayo Bello, Xi Chen, Jufang He

“…Here, we uncover that exogenous CCK potentiates the excitatory synaptic transmission in the CA1-SUB projections via CCK-B receptor. …”
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Nucleolar PARP-1 Expression Is Decreased in Alzheimer’s Disease: Consequences for Epigenetic Regulation of rDNA and Cognition by Jianying Zeng, Jenny Libien, Fatima Shaik, Jason Wolk, A. Iván Hernández

“…Synaptic dysfunction is thought to play a major role in memory impairment in Alzheimer’s disease (AD). …”
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Relationship between enriched environment and neurodegeneration: a review from mechanism to therapy by Yuan-qiao Xu, Yanjiao Chen, Jia-xin Xing, Jun Yao

“…We discussed the molecular underpinnings of the effects of EE, including modulation of key signaling pathways such as extracellular regulated kinase 1/2 (ERK1/2), mitogen-activated protein kinases (MAPK), and AMPK/SIRT1, which were implicated in neuroprotection and synaptic plasticity. Additionally, we scrutinized the influence of EE on epigenetic modifications and autophagy, processes pivotal to ND pathogenesis. …”
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Rapid nongenomic estrogen signaling controls alcohol drinking behavior in mice by Lia J. Zallar, Jean K. Rivera-Irizarry, Peter U. Hamor, Irena Pigulevskiy, Ana-Sofia Rico Rozo, Hajar Mehanna, Dezhi Liu, Jacqueline P. Welday, Rebecca Bender, Joseph J. Asfouri, Olivia B. Levine, Mary Jane Skelly, Colleen K. Hadley, Kristopher M. Fecteau, Scottie Nelson, John Miller, Pasha Ghazal, Peter Bellotti, Ashna Singh, Lauren V. Hollmer, David W. Erikson, Jacob Geri, Kristen E. Pleil

“…The pro-drinking, but not anxiolytic, effect of high endogenous estrogen occurred via rapid signaling at membrane-associated estrogen receptor alpha in the bed nucleus of the stria terminalis, which promoted synaptic excitation of corticotropin-releasing factor neurons and facilitated their activity during alcohol drinking. …”
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Modulation of CREB in the Dorsal Lateral Geniculate Nucleus of Dark-Reared Mice by Thomas E. Krahe, Tania A. Seabrook, Ching-Kang J. Chen, Michael A. Fox, William Guido

“…DR disrupts retinogeniculate synaptic strength and pruning in mice, but only when DR starts one week after eye opening (delayed DR, DDR) and not after chronic DR (CDR) from birth. …”
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