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301
Advanced ferroelectric oxide films and heterostructures for unconventional applications
Published 2025-12-01“…In addition, we also summarize the applications of ferroelectrics, including ferroelectric diodes and ferroelectric tunnel junctions, synaptic devices, domain-wall-based devices, and photoelectric devices, highlighting their significant potential for advanced electronic and optoelectronic devices. …”
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302
Optimization of Leaky Integrate-and-Fire Neuron Circuits Based on Nanoporous Graphene Memristors
Published 2024-01-01“…Circuit parameters like the synaptic resistance and membrane capacitance act as additional control parameters whereby the spike frequency of the circuit can be effectively controlled. …”
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303
Intestinal microbiome as effective regulator of enteral and central nervous system activity
Published 2018-08-01“…No evidence of direct involvement of these neurotransmitters in regulation of proximal enteral neurons synaptic activity is obtained. However the fact of neurotransmitter production in close proximity to intestinal wall creates a basis for the further studies. …”
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304
Role of serotonin in physiology and diseases of gastro-intestinal tract
Published 2012-04-01“…Authors discuss receptor-specific effects of serotonin on blood-tissue barriers of GIT, synaptic transmission, regulation of local and systemic afferentation, motility of the stomach and intestine, and mechanisms of defense. …”
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305
Neuropeptidomics: Mass Spectrometry-Based Identification and Quantitation of Neuropeptides
Published 2016-03-01“…Neuropeptides bind to post-synaptic receptors and elicit cellular effects like classical neurotransmitters. …”
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306
Mechanisms underlying CSD initiation implicated by genetic mouse models of migraine
Published 2025-01-01“…These models, all generated from families with hereditary migraine, allow the investigation of the functional consequences of disease-causing mutations at the molecular, cellular, synaptic and neural circuit levels. In this review, after describing the available genetic mouse models of migraine, which all share increased susceptibility to experimentally induced CSD, we will discuss the functional alterations in their cerebral cortex and the mechanisms underlying the facilitation of CSD initiation in their cortex, as well as the insights that these mechanisms may give into the mechanisms of initiation of spontaneous CSDs in migraine.…”
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307
Pathological Plasticity in Fragile X Syndrome
Published 2012-01-01“…These processes include synaptic, cell intrinsic, and homeostatic mechanisms both dependent on and independent of abnormal metabotropic glutamate receptor transmission. …”
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308
Neuroimaging Insights into Autism Spectrum Disorder: Structural and Functional Brain
Published 2024-09-01“…Postmortem research reveals cellular and synaptic changes, such as fewer Purkinje cells and altered neuron organization. …”
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309
Hodological patterning as an organizing principle in vertebrate motor circuitry
Published 2025-01-01“…Hodological patterning refers to developmental mechanisms that link the location of neurons in the brain or spinal cord to specific axonal trajectories that direct connectivity to synaptic targets either within the central nervous system or in the periphery. …”
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310
Fully Connected Neural Networks Ensemble with Signal Strength Clustering for Indoor Localization in Wireless Sensor Networks
Published 2015-12-01“…Sensor nodes have to store only the signal strength prototypes and synaptic weights of the ANNs in order to estimate their locations. …”
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311
Neuroprotection by chronic administration of Fluoroethylnormemantine (FENM) in mouse models of Alzheimer's disease
Published 2025-01-01“…Markers of neuroinflammation, apoptosis, oxidative stress, and amyloid burden in APP/PS1 mice, were quantified. Markers of synaptic plasticity such as PSD-95 and GluN2A/B/D subunits expression in hippocampus homogenates or synaptosomes were quantified in Aβ25–35-treated mice and synaptic long-term potentiation (LTP) in hippocampal slices was analysed in APP/PS1 mice. …”
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312
Presynaptic CRF1 Receptors Mediate the Ethanol Enhancement of GABAergic Transmission in the Mouse Central Amygdala
Published 2009-01-01“…These data indicate that presynaptic CRF1 receptors play a critical role in permitting or mediating ethanol enhancement of GABAergic synaptic transmission in CeA, via increased vesicular GABA release, and thus may be a rational target for the treatment of alcohol abuse and alcoholism.…”
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313
The Role of GABAergic Inhibition in Ocular Dominance Plasticity
Published 2011-01-01“…This brings the hope that novel treatments can be developed for brain injuries requiring renewed plasticity potential and neurodevelopmental brain disorders caused by defective synaptic plasticity. One of the central mechanisms responsible for opening the sensitive period is the maturation of inhibitory innervation. …”
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314
Calcium Signalling in Neurological Disorders, with Insights from Miniature Fluorescence Microscopy
Published 2024-12-01“…Additionally, calcium functions as a ubiquitous second messenger involved in diverse cellular processes, from synaptic activity to intercellular communication, making it a potential therapeutic target. …”
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315
Morphological and functional convergence of visual projection neurons from diverse neurogenic origins in Drosophila
Published 2025-01-01“…There are ~20 classes of LCNs forming non-overlapping synaptic optic glomeruli in the brain. To address their origin, we used single-cell mRNA sequencing to define the transcriptome of LCN subtypes and identified lines that are expressed throughout their development. …”
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316
Palmitoylation as a Functional Regulator of Neurotransmitter Receptors
Published 2018-01-01“…From the functional point of view, palmitoylation affects a wide span of neurotransmitter receptors activities including their trafficking, sorting, stability, residence lifetime at the cell surface, endocytosis, recycling, and synaptic clustering. This review summarizes the current knowledge on the palmitoylation of neurotransmitter receptors and its role in the regulation of receptors functions as well as in the control of different kinds of physiological and pathological behavior.…”
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317
Alzheimer’s Disease as a Result of Stimulus Reduction in a GABA-A-Deficient Brain: A Neurocomputational Model
Published 2020-01-01“…This model allows one to analyze the initial phases of Alzheimer’s disease by “aging” the artificial koniocortex through synaptic pruning, by the modification of acetylcholine and GABA-A signaling, and by reducing sensory stimuli, among other processes. …”
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318
Dopaminergic signaling to ventral striatum neurons initiates sniffing behavior
Published 2025-01-01“…Both the firing of individual neurons and the activity of post-synaptic D1 and D2 dopamine receptor-expressing neurons are coupled with sniffing and local antagonism of D1 and D2 receptors squelches sniffing. …”
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319
Microglial Dysregulation in Psychiatric Disease
Published 2013-01-01“…More recently, they have been shown to have a number of important roles beyond immune surveillance and response, including synaptic pruning during development and the support of adult neurogenesis. …”
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320
Minimally invasive exoscope-assisted coccygectomy: A novel approach for chronic refractory coccydynia
Published 2025-01-01“…Case Description: A 40-year-old female patient with persistent pain unresponsive to conservative treatments underwent this advanced procedure. Utilizing the Synaptive exoscope-microscope system, the surgery allowed for precise dissection and removal of affected coccygeal segments, with a focus on minimizing skin and soft tissue disruption to optimize wound healing and surgical site pain. …”
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