Role and modulation of various spinal pathways for human upper limb control in different gravity conditions. by Alice Bruel, Lina Bacha, Emma Boehly, Constance De Trogoff, Luca Represa, Gregoire Courtine, Auke Ijspeert

“…In the second optimisation context, the modulation of the spinal synaptic strengths also remarkably reproduced the target trajectory for the mild gravity changes. …”
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Olfactory transport efficiency of the manganese oxide nanoparticles (II) after their single or multiple intranasal administrations by A. V. Romashchenko, M. B. Sharapova, D. V. Petrovskii, M. P. Moshkin

“…In this case, the concentration of particles in the olfactory bulb was proportional to the volume of the structure, which in particular depends on the number of synaptic contacts between the mitral cell of the olfactory bulb (OB) and olfactory epithelium (OE). …”
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The molecular view of mechanical stress of brain cells, local translation, and neurodegenerative diseases by T. M. Khlebodarova

“…However, the molecular mechanisms that underlie the way from cell exposure to mechanical stress to disturbances in synaptic plasticity followed by changes in behavior, cognition, and memory are still poorly understood. …”
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Test-Retest Reliability of Homeostatic Plasticity in the Human Primary Motor Cortex by Tribikram Thapa, Siobhan M. Schabrun

“…Homeostatic plasticity regulates synaptic activity by preventing uncontrolled increases (long-term potentiation) or decreases (long-term depression) in synaptic efficacy. …”
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Investigating the Therapeutic Mechanisms of Total Saikosaponins in Alzheimer’s Disease: A Metabolomic and Proteomic Approach by Huiling Wei, Tianyi Du, Weiwei Zhang, Wei Ma, Yao Yao, Juan Li

“…<b>Conclusions</b>: Our findings suggest that TSS ameliorate cognitive decline through regulating neuroinflammatory pathways, cAMP and cGMP signaling, and synaptic plasticity pathways, providing insights into its therapeutic potential in AD.…”
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Projections from thalamic nucleus reuniens to hippocampal CA1 area participate in context fear extinction by affecting extinction-induced molecular remodeling of excitatory synapse... by Magdalena Ziółkowska, Narges Sotoudeh, Anna Cały, Monika Puchalska, Roberto Pagano, Malgorzata Alicja Śliwińska, Ahmad Salamian, Kasia Radwanska

“…We also observe CFE-specific structural changes of excitatory synapses and expression of the synaptic scaffold protein, PSD-95, in both strata innervated by RE, but not in SR. …”
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Novel histone deacetylase-5 inhibitor T2943 exerts an anti-depressive effect in mice by enhancing GRID1 expression by Juan Du, Ruyun Liu, Lin Ma, Yue Liu, Wei Wei, Ning Liu, Qiuhua Cao, Jianqiang Yu

“…Upregulated GRID1 mediates signal transmission in neural pathways, restores the regenerative ability of hippocampal nerve cells, promotes nerve growth and synaptic formation, increases synapse numbers, and enhances synaptic function. …”
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Exploratory analysis of a Novel RACK1 mutation and its potential role in epileptic seizures via Microglia activation by Sai Zhang, Zhaofei Dong, Jing Guo, Ze Li, Hong Wu, Linming Zhang, Fuli Min, Tao Zeng

“…Our findings reveal that the RACK1-p.L206P mutation significantly enhances proliferation, migration, phagocytic ability, and inflammatory activation in human microglia, which in turn affects neuronal excitability and synaptic function, culminating in typical seizure symptoms in the seizures. …”
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Electroacupuncture Alleviated Referral Hindpaw Hyperalgesia via Suppressing Spinal Long-Term Potentiation (LTP) in TNBS-Induced Colitis Rats by Pei-Ran Lv, Yang-Shuai Su, Wei He, Xiao-Yu Wang, Hong Shi, Xiao-Ning Zhang, Bing Zhu, Yu Kan, Li-Zhen Chen, Qiao-Feng Wu, Shu-Guang Yu, Xiang-Hong Jing

“…Spinal long-term potentiation (LTP) of nociceptive synaptic transmission plays a critical role in the development of somatic hyperalgesia in chronic pain conditions. …”
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Existence of Wave Front Solutions of an Integral Differential Equation in Nonlinear Nonlocal Neuronal Network by Lijun Zhang, Linghai Zhang, Jie Yuan, C. M. Khalique

“…The kernel functions we study here include pure excitations, lateral inhibition, lateral excitations, and more general synaptic couplings (e.g., oscillating kernel functions). …”
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Mammalian Cochlear Hair Cell Regeneration and Ribbon Synapse Reformation by Xiaoling Lu, Yilai Shu, Mingliang Tang, Huawei Li

“…In this review, we discuss the research progress in HC regeneration, the synaptic plasticity, and the reinnervation of new regenerated HCs in mammalian inner ear.…”
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Combination Therapy with Platelet-Rich Plasma and Epidermal Neural Crest Stem Cells Increases Treatment Efficacy in Vascular Dementia by Somayeh Akbari, Masoud Haghani, Mojtaba Ghobadi, Etrat Hooshmandi, Afshin Borhani Haghighi, Mohammad Saied Salehi, Sareh Pandamooz, Negar Azarpira, Afsoon Afshari, Shahrbanoo Zabihi, Marzieh Nemati, Mahnaz Bayat

“…The results demonstrated impaired learning, memory, and synaptic plasticity in the 2VO rats, along with a significant decrease in the expression of IGF-1, TGF-β1, PSD-95, and upregulation of GSK-3β. …”
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Transcriptomic and Functional Landscape of Adult Human Spinal Cord NSPCs Compared to iPSC-Derived Neural Progenitor Cells by Sasi Kumar Jagadeesan, Ahmad Galuta, Ryan Vimukthi Sandarage, Eve Chung Tsai

“…Enrichment of pathways related to neurogenesis, axon guidance, and synaptic signaling varied across donors, highlighting the impact of genetic and epigenetic individuality on NSPC behavior.…”
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Synapsis and recombination of autosomes and sex chromosomes in two terns (Sternidae, Charadriiformes, Aves) by A. P. Lisachov, L. P. Malinovskaya, A. V. Druzyaka, P. M. Borodin, A. A. Torgasheva

“…We investigated the synaptic patterns of the heteromor phic Z and W chromosomes, localized the pseudoautosomal regions and estimated their lengths. …”
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The role of CXCL12/CXCR4/CXCR7 axis in cognitive impairment associated with neurodegenerative diseases by Rojin Sarallah, Shima Jahani, Alireza Soltani Khaboushan, Amir Kian Moaveni, Maryam Amiri, Masoumeh Majidi Zolbin

“…Across these diseases, the axis influences neuroinflammation, synaptic plasticity, and neuronal survival through various signaling cascades, including PI3K/AKT, MAPK, and JAK/STAT pathways. …”
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Glia control experience-dependent plasticity in an olfactory critical period by Hans C Leier, Alexander J Foden, Darren A Jindal, Abigail J Wilkov, Paola Van der Linden Costello, Pamela J Vanderzalm, Jaeda Coutinho-Budd, Masashi Tabuchi, Heather T Broihier

“…EB exposure for the first 2 days post-eclosion drives large-scale reductions in glomerular volume, presynapse number, and post- synaptic activity. Crucially, pruning during the critical period has long-term consequences for circuit function since both OSN-PN synapse number and spontaneous activity of PNs remain persistently decreased following early-life odor exposure. …”
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Astrocytes and Developmental Plasticity in Fragile X by Connie Cheng, Mary Sourial, Laurie C. Doering

“…Alterations in the partnership between astrocytes and neurons have now emerged as important mechanisms that underlie neuropathology. With overall synaptic function standing as a prominent link to the expression of the disease phenotype in a number of neurodevelopmental disorders and knowing that astrocytes influence synapse development and function, this paper highlights the current knowledge of astrocyte biology with a focus on their involvement in fragile X syndrome.…”
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Noise-Induced Hearing Loss: Updates on Molecular Targets and Potential Interventions by Huanyu Mao, Yan Chen

“…Noise overexposure leads to hair cell loss, synaptic ribbon reduction, and auditory nerve deterioration, resulting in transient or permanent hearing loss depending on the exposure severity. …”
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Sleep Spindles as Facilitators of Memory Formation and Learning by Daniel Ulrich

“…Concomitant neurophysiological experiments showed a close relationship between sleep spindles and other sleep related EEG rhythms as well as a relationship between sleep spindles and synaptic plasticity. Together, there is growing evidence from several disciplines in neuroscience for a participation of sleep spindles in memory formation and learning.…”
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On the return process with refractoriness for a non-homogeneous Ornstein-Uhlenbeck neuronal model by Virginia Giorno, Serena Spina

“…We assume that the neuron is subject to a sequence of inhibitory and excitatory post-synaptic potentials that occur with time-dependent rates. …”
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