Neuron-Glia Interactions in Neural Plasticity: Contributions of Neural Extracellular Matrix and Perineuronal Nets by Egor Dzyubenko, Christine Gottschling, Andreas Faissner

“…The components of the ECM have been detected near glial processes, which abut onto the CNS synaptic unit, where they are part of the specialized macromolecular assemblies, termed perineuronal nets (PNNs). …”
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An Area-Efficient Integrate-and-Fire Neuron Circuit with Enhanced Robustness against Synapse Variability in Hardware Neural Network by Arati Kumari Shah, Kannan Udaya Mohanan, Jisun Park, Hyungsoon Shin, Eou-Sik Cho, Seongjae Cho

“…Here, practical neuron circuits must overcome the variations arising from nonideal behaviors of synaptic devices, such as stuck-at-fault and conductance deviation. …”
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Immune Challenge Alters Reactivity of Hippocampal Noradrenergic System in Prenatally Stressed Aged Mice by Gayane Grigoryan, Niklas Lonnemann, Martin Korte

“…A PS-induced proinflammatory status of the organism may result in an impairment of both hippocampal synaptic plasticity and hippocampus-dependent memory formation in adults. …”
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Cochlear Synaptopathy and Noise-Induced Hidden Hearing Loss by Lijuan Shi, Ying Chang, Xiaowei Li, Steve Aiken, Lijie Liu, Jian Wang

“…Here, we provide a brief review to address several critical issues related to NIHHL: (1) the mechanism of noise induced synaptic damage, (2) reversibility of the synaptic damage, (3) the functional deficits as the nature of NIHHL in animal studies, (4) evidence of NIHHL in human subjects, and (5) peripheral and central contribution of NIHHL.…”
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Hippocampal Dendritic Spines Are Segregated Depending on Their Actin Polymerization by Nuria Domínguez-Iturza, María Calvo, Marion Benoist, José Antonio Esteban, Miguel Morales

“…Spines receive the majority of glutamatergic synaptic inputs. Their morphology, dynamics, and density have been related to synaptic plasticity and learning. …”
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Early-life stress induces persistent astrocyte dysfunction associated with fear generalisation by Mathias Guayasamin, Lewis R Depaauw-Holt, Ifeoluwa I Adedipe, Ossama Ghenissa, Juliette Vaugeois, Manon Duquenne, Benjamin Rogers, Jade Latraverse-Arquilla, Sarah Peyrard, Anthony Bosson, Ciaran Murphy-Royal

“…These behavioural changes were associated with impaired synaptic plasticity, increased neural excitability, and astrocyte hypofunction. …”
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Action inflexibility and compulsive-like behavior accompany neurobiological alterations in the anterior orbitofrontal cortex and associated striatal nuclei by Laura M. Butkovich, Sophie T. Yount, Aylet T. Allen, Esther H. Seo, Andrew M. Swanson, Shannon L. Gourley

“…They also display higher levels of the excitatory synaptic marker striatin in the nucleus accumbens and lower levels of the excitatory synaptic marker SAPAP3 in the dorsal striatum, striatal nuclei that receive input from the anterior OFC. …”
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Evidence of Maintenance Tagging in the Hippocampus for the Persistence of Long-Lasting Memory Storage by Micol Tomaiuolo, Cynthia Katche, Haydee Viola, Jorge H. Medina

“…The synaptic tagging and capture (STC) hypothesis provides a compelling explanation for synaptic specificity and facilitation of long-term potentiation. …”
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Comparative proteomic analysis of astrocytoma tissues from patients with and without seizures by Thanakorn Khaosuwan, Kittinun Leetanaporn, Pongsakorn Choochuen, Raphatphorn Navakanitworakul, Anukoon Kaewborisutsakul, Thara Tunthanatip, Surasak Sangkhathat, Wararat Chiangjong, Kanitpong Phabphal

“…Proteins downregulated in patients with seizures included those involved in trans-synaptic signalling and gamma-aminobutyric acid synaptic transmission. …”
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In Vivo Plasticity at Hippocampal Schaffer Collateral-CA1 Synapses: Replicability of the LTP Response and Pharmacology in the Long-Evans Rat by A. Ahnaou, E. White, R. Biermans, N. V. Manyakov, W. H. I. M. Drinkenburg

“…Results: (1) When compared to Sprague-Dawley (SD) rats, the HFS using a stimulus intensity of 50% of the maximum slope obtained from input/output (I/O) curves elicited lower and higher thresholds of synaptic plasticity responses in SD and LE rats, respectively. …”
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CREB Regulates Experience-Dependent Spine Formation and Enlargement in Mouse Barrel Cortex by Annabella Pignataro, Antonella Borreca, Martine Ammassari-Teule, Silvia Middei

“…Experience modifies synaptic connectivity through processes that involve dendritic spine rearrangements in neuronal circuits. …”
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Coincidence Detection Using Spiking Neurons with Application to Face Recognition by Fadhlan Kamaruzaman, Amir Akramin Shafie, Yasir M. Mustafah

“…We elucidate the practical implementation of Spiking Neural Network (SNN) as local ensembles of classifiers. Synaptic time constant τs is used as learning parameter in representing the variations learned from a set of training data at classifier level. …”
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Chronic Fluoxetine Treatment Suppresses Plasticity (Long-Term Potentiation) in the Mature Rodent Primary Auditory Cortex In Vivo by Hans C. Dringenberg, Leora R. Branfield Day, Deanna H. Choi

“…Several recent studies have provided evidence that chronic treatment with the selective serotonin reuptake inhibitor (SSRI) fluoxetine can facilitate synaptic plasticity (e.g., ocular dominance shifts) in the adult central nervous system. …”
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Neurophysiology of Drosophila Models of Parkinson’s Disease by Ryan J. H. West, Rebecca Furmston, Charles A. C. Williams, Christopher J. H. Elliott

“…We provide an insight into the role Drosophila has played in elucidating neurophysiological perturbations associated with Parkinson’s disease- (PD-) related genes. Synaptic signalling deficits are observed in motor, central, and sensory systems. …”
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Identification of Neurons Containing Calcium-Permeable AMPA and Kainate Receptors Using Ca2+ Imaging by Sergei Gaidin, Artem Kosenkov, Valery Zinchenko, Bakytzhan Kairat, Arailim Malibayeva, Sultan Tuleukhanov

“…Calcium-permeable AMPA receptors (CP-AMPARs) and kainate receptors (CP-KARs) play crucial roles in synaptic plasticity and are implicated in various neurological processes. …”
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A hypothesis about interrelations of epigenetic factors and transposable elements in memory formation by R. N. Mustafin

“…Therefore, long-term memory is preserved after elimination of synaptic connections. This is confirmed by the fact that the proteins involved in memory formation, including the transfer of genetic information through synapses between neurons (Arc protein), originate from transposons. …”
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Investigation of Cortical Signal Propagation and the Resulting Spatiotemporal Patterns in Memristor-Based Neuronal Network by Ke Ding, Zahra Rostami, Sajad Jafari, Boshra Hatef

“…It also is reported to be able to emulate synaptic long-term plasticity as well as short-term plasticity. …”
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Functional characterization of endocytic signals in the SynDIG/PRRT family members SynDIG1 and SynDIG4 in heterologous cells and neurons by David J. Speca, Chun-Wei He, Christina M. Meyer, Erin C. Scott, Erin C. Scott, Elva Díaz

“…The transmembrane protein Synapse Differentiation Induced Gene 4 (SynDIG4), also known as Proline-rich transmembrane protein 1 (PRRT1), is an AMPA-type glutamate receptor (AMPAR) auxiliary factor that is necessary for maintaining extra-synaptic pools of GluA1. Loss of SynDIG4, and the subsequent decrease in extra-synaptic GluA1, has been found to significantly impact synaptic plasticity in the hippocampus. …”
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Long-Standing Motor and Sensory Recovery following Acute Fibrin Sealant Based Neonatal Sciatic Nerve Repair by Natalia Perussi Biscola, Luciana Politti Cartarozzi, Rui Seabra Ferreira Junior, Benedito Barraviera, Alexandre Leite Rodrigues de Oliveira

“…Coaptation preserved synaptic covering on lesioned motoneurons and led to neuronal survival. …”
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Decoding HIV-associated neurocognitive disorders: a new perspective from multimodal connectomics by Zhongkai Zhou, Wei Wang, Hui Li, Ying Shi, Lingling Zhao, Yibo Lu, Xingchen Wei, Hongjun Li

“…HAND involves the vulnerability of neural circuits caused by synaptic degeneration and abnormal synaptic pruning. …”
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