First-in-human exploratory trial assessing safety, feasibility, and efficacy of artificial protein (silk-elastin) in promoting healing in patients with meniscus injuries by Masakazu Ishikawa, Shunya Tsuji, Goki Kamei, Kyohei Nakata, Akinori Nekomoto, Naofumi Hashiguchi, Tomoyuki Nakasa, Atsuo Nakamae, Naosuke Kamei, Keiichiro Inoue, Shingo Kawabata, Keiko Ueda, Nobuo Adachi

“…No adverse events or reactions were attributed to SE. At 3 months post-surgery, clinical outcomes and repair sites were evaluated using MRI and arthroscopy. …”
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Nuclear farnesoid X receptor protects against bone loss by driving osteoblast differentiation through stabilizing RUNX2 by Qi Dong, Haoyuan Fu, Wenxiao Li, Xinyu Ji, Yingchao Yin, Yiran Zhang, Yanbo Zhu, Guoqiang Li, Huiyang Jia, Heng Zhang, Haofei Wang, Jinglue Hu, Ganggang Wang, Zhihao Wu, Yingze Zhang, Sujuan Xu, Zhiyong Hou

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Spina Bifida Occulta with Bilateral Spondylolysis at the Thoracolumbar Junction Presenting Cauda Equina Syndrome by Kentaro Mataki, Masao Koda, Yosuke Shibao, Hiroshi Kumagai, Katsuya Nagashima, Kousei Miura, Hiroshi Noguchi, Toru Funayama, Tetsuya Abe, Masashi Yamazaki

“…Posterior interbody fusion and decompression at L1-2 were performed. After surgery, his muscle power recovered to normal strength. …”
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Efficacy of PDD-guided tumor excision combined with photodynamic therapy in cutaneous squamous cell carcinoma by Nan Yang, Yunchuan Yang, Wanqi Zhang, Xinying Li, Hao Jiang, Huiling Kou, Junbo Zhang, Yuanyuan Wang, Liuchang Tan, Yuangang Lu

“…Both groups were subjected to frozen section analysis, and PDT was applied during and post-surgery. Results: The negative margin rate in the PDD group was 98.6 %, significantly higher than the 69.2 % observed in the non-PDD group. …”
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Sonographic Assessment of Intravascular Fluid Estimate (SAFE) Score by Using Bedside Ultrasound in the Intensive Care Unit by Keith Killu, Victor Coba, Dionne Blyden, Semeret Munie, Darlene Dereczyk, Pridvi Kandagatla, Amy Tang

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Necrotizing Fasciitis of the Chest in a Neonate in Southern Nigeria by Oluwafemi Olasupo Awe, Emeka B. Kesieme, Babatunde Kayode-Adedeji, Quinzy O. Aigbonoga

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Hybrid Solution for Mycotic Pseudoaneurysm of Carotid Bifurcation by Giuseppe Deiana, Antonio Baule, Genadi Genadiev Georgiev, Mario Moro, Francesco Spanu, Flavia Urru, Stefano Camparini

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Dedifferentiated Low-Grade Central Osteosarcoma of the Mandible by Kenji Yamagata, Naomi Ishibashi-Kanno, Ryota Matsuoka, Fumihiko Uchida, Satoshi Fukuzawa, Hiroki Bukawa

“…The patient showed no recurrence or lung metastasis 3 years after the final surgery.…”
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Open and Minimal Approaches to Pancreatic Adenocarcinoma by Ricky H. Bhogal, Stephanos Pericleous, Aamir Z. Khan

“…Whilst traditional open surgery remains the most frequent approach for surgery, the specific steps during surgery may need to be modified in light of the aforementioned neoadjuvant treatments. …”
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Exacerbation of Ulcerative Colitis following Administration of 5-ASA Enemas by Barbara A. Young, Robin S. McLeod, Zane Cohen

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Successful Treatment of Whole Coronary Artery Spasm after Off-Pump Coronary Artery Bypass Grafting by Akihiro Kobayashi, Yoshimori Araki, Takafumi Terada, Osamu Kawaguchi

“…Although coronary artery spasm after off-pump coronary artery bypass surgery is a rare condition, it must be suspected when sudden circulatory collapse occurs.…”
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Reconstructive Osteotomy for Ankle Malunion Improves Patient Satisfaction and Function by Fumiaki Inori, Masahiko Tohyama, Hiroyuki Yasuda, Sadahiko Konishi, Akeo Waseda

“…Treatment of chronic symptoms caused by a malunion is a difficult problem in orthopedic surgery. We encountered a case of ankle malunion at our hospital about 1 year after the first operation. …”
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Amalgam Tattoo Mimicking Mucosal Melanoma: A Diagnostic Dilemma Revisited by K. Lundin, G. Schmidt, C. Bonde

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Intra-Articular Dislocation of the Patella by Gavin McHugh, Ed Ryan, May Cleary, Paddy Kenny, Shea O'Flanagan, Peter Keogh

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Rare Appendicitis-Like Syndrome: The Case of the Obstructing Broccoli by Stephen Jones, Patrick Narh-Martey, Mitun Patel, Amanpreet Dhaliwal, Jessica Persson, Denis Orr

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Skeletal Muscle Metastases to the Flexor Digitorum Superficialis and Profundus from Urothelial Cell Carcinoma and Review of the Literature by Marco Guidi, Cesare Fusetti, Stefano Lucchina

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Pilot study of a comprehensive multidisciplinary inpatient-based approach to smoking cessation in patients with vascular disease by Tanner Kim, MD, Anand Brahmandam, MBBS, Dana Alameddine, MD, Rachel Forman, MD, Amin Hardik, MD, Lisa Fucito, PhD, Carlos Mena-Hurtado, MD, Raul Guzman, MD, Cassius Iyad Ochoa Chaar, MD, MS, MPH

“…Methods: Adult smokers with occlusive or aneurysmal arterial disease admitted after vascular surgery in a tertiary care center were enrolled. Patients received brief counselling sessions regarding smoking cessation from specialties including vascular surgery, cardiology, neurology, and the smoking cessation program during the hospitalization using the gain-frame approach. …”
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Dual-positive gastric cancer: an extremely malignant subtype of gastric cancer with high serum alpha-fetoprotein and carcinoembryonic antigen concentrations by Weixun Xie, Chengyu Hu, Hongming Liu, Zelai Wu, Bixian Luo, Xiaoying Wu, Xiaoying Wu, Chuanlei Tuo, Ziyin Deng, Han Liang, Yong Liu, Weihua Gong, Weihua Gong

“…Immunochemotherapy is a viable option for DPGC patients who cannot undergo surgery.…”
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Oncometabolite D-2HG drives tumor metastasis and protumoral macrophage polarization by targeting FTO/m6A/ANGPTL4/integrin axis in triple-negative breast cancer by Siyue Zhang, Ning Zhang, Tong Wan, Yinqiao He, Jie Hao, Yiwei Liu, Yidong Liu, Bing Chen, Wenjing Zhao, Lijuan Wang, Dan Luo, Chao Gao, Qifeng Yang

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Giant Malignant Phyllodes Tumour of Breast by Ramakrishnan Krishnamoorthy, Thejas Savasere, Vinod Kumar Prabhuswamy, Rajashekhara Babu, Sadashivaiah Shivaswamy

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